Kinase, in vitro: 

An enzyme-substrate reaction that occurs in non-living experimental conditions such as a test tube. For example, a purified enzyme is reacted with a substrate protein or mixture of proteins or peptides.

ERK1 T699-p , S1051-p
 Putative in vivo kinases: 

An enzyme-substrate reaction that occurs within living cells; includes cultured cells, ex vivo samples, and intact organisms. In the case of kinases, the large number of protein kinases in intact cells makes exact identification of the responsible kinase challenging.

HER4 Y1056-p , Y1162-p , Y1284-p
Treatment:
lapatinib Y1162-p , Y1284-p
phorbol_ester T699-p , S1051-p , Y1284-p
Trametinib T699-p , Y1284-p