Kinase, in vitro: 

An enzyme-substrate reaction that occurs in non-living experimental conditions such as a test tube. For example, a purified enzyme is reacted with a substrate protein or mixture of proteins or peptides.

Abl Y1016-p , Y1092-p , Y1197-p
Akt1 S229-p
Akt2 S229-p
EGFR Y869-p , Y1016-p , Y1092-p , Y1110-p , Y1172-p , Y1197-p
ERK1 T693-p
ERK2 T693-p
P38A S1039-p , T1041-p
P38B S1039-p , T1041-p
PKCA T678-p
PKCA T678-p
PKCD T678-p
PKCE T678-p
PKG2 T430-p , T693-p
PKN1 T678-p
Src iso1 Y869-p , Y1092-p
Src Y869-p , Y915-p , Y944-p , Y1016-p , Y1092-p , Y1110-p
 Putative in vivo kinases: 

An enzyme-substrate reaction that occurs within living cells; includes cultured cells, ex vivo samples, and intact organisms. In the case of kinases, the large number of protein kinases in intact cells makes exact identification of the responsible kinase challenging.

Akt1 S229-p
AMPKA1 T892-p
CAMK2A S768-p , S1070-p , S1071-p , S1081-p , S1166-p
CDK1 S1026-p
EGFR Y1016-p , Y1092-p , Y1110-p , Y1172-p , Y1197-p
ERK1 T693-p
ERK2 T693-p
P38A T693-p
PKCA T678-p
PKG2 T430-p
PKN1 T678-p
PKN3 T678-p
Src Y727-p , Y764-p , Y869-p , Y915-p , Y944-p , Y1016-p , Y1125-p
Phosphatases, in vitro:
PTP1B Y1092-p
PTPN3 Y1197-p
PTPRG Y1092-p
SHP-2 Y869-p , Y1016-p
Putative upstream phosphatases:
DUSP3 Y869-p
PTPRA Y1016-p
SHP-2 Y1016-p
Regulatory protein:
14-3-3 sigma Y1069-p , Y1092-p
ACE Y1110-p
ADAM12 Y1197-p
AMPKA1 Y1197-p
BTG2 Y1110-p
CAMP Y869-p , Y1069-p
CASP8 Y869-p , Y1125-p
caveolin-1 Y1197-p
Cbl-b Y1197-p
CBL Y1197-p
CDCP1 Y1092-p
CDH1 Y1110-p
CENPJ Y1092-p
CSFR Y1172-p , Y1197-p
CXCL1 Y1092-p
CXCL5 Y1092-p
CYBA Y1092-p
DAPK3 Y869-p , Y1016-p , Y1092-p , Y1197-p
DFNA5 Y1069-p , Y1197-p
DGKD Y869-p , Y1016-p , Y1092-p , Y1197-p
DLX3 Y1092-p , Y1197-p
DSG2 Y1172-p , Y1197-p
DSG3 S695-p , Y1092-p , Y1110-p
DUOX1 Y869-p , Y1092-p
DYN1 T693-p
EGFR Y727-p , Y869-p , Y998-p , Y1016-p , S1039-p , T1041-p , Y1069-p , Y1092-p , Y1110-p , Y1138-p , S1162-p , Y1172-p , Y1197-p
EGF Y869-p , Y1092-p
Epiregulin Y869-p , Y1092-p , Y1197-p
EXTL2 Y1092-p , Y1110-p
EXTL3 Y1092-p , Y1110-p
FGF7 Y1092-p
FGFR1 T693-p
FGFR2 T693-p
FLOT1 Y1197-p
FLOT2 Y1092-p , Y1197-p
GAS6 Y1197-p
GPNMB Y869-p
GRP78 Y869-p , Y1092-p
H2AX Y869-p
HER2 Y869-p , Y1092-p
HRas Y1110-p
HSP70 Y1092-p
HUNK Y869-p , Y1016-p , Y1092-p
IL2RA Y1110-p
ITGB4 Y869-p , Y1092-p
LRRK1 Y1092-p
Mer Y869-p , Y1016-p , Y1092-p , Y1197-p
MKK3 Y1092-p
MKK6 Y1092-p
Musashi-2 Y869-p , Y1016-p , Y1092-p
NDRG1 Y1092-p , Y1172-p
NUMB Y1069-p
P130Cas Y869-p
P38A Y869-p , Y1092-p , Y1197-p
P38B Y869-p , Y1092-p , Y1197-p
P38D Y869-p , Y1092-p , Y1197-p
P38G Y869-p , Y1092-p , Y1197-p
PAK4 Y869-p
PFKFB1 Y869-p , Y1016-p , Y1092-p , Y1197-p
PINK1 Y1092-p
PKCA T678-p
PKG2 Y1092-p , Y1197-p
PTEN Y1092-p
PTPRJ Y869-p , Y1092-p
PTPRK Y869-p
RAB11A T693-p
RAB11FIP1 T693-p
Rab4 Y1092-p
S100A7 Y1092-p , Y1197-p
SHC4 Y1092-p
SIAT1 Y1092-p
SOCS2 Y869-p
SQSTM1 Y1197-p
Src Y869-p , Y1016-p , Y1092-p , Y1110-p
SRXN1 Y869-p , Y1016-p , K1061-ac , Y1092-p , Y1110-p , Y1172-p , Y1197-p
ST3GAL4 Y1092-p
ST3GAL5 T678-p
TBCK Y869-p , Y1016-p , Y1092-p , Y1197-p
TBK1 T993-p , Y1172-p , Y1197-p
TGFalpha T693-p , Y869-p , Y1092-p
TNK1 Y869-p , Y1016-p , Y1092-p
TPD52L3 Y869-p , Y1016-p , Y1092-p , Y1197-p
TSPAN6 Y1197-p
TTP T693-p
TXLNA Y869-p , S1070-p , S1071-p
UCK1 Y869-p , Y1016-p , Y1092-p , Y1197-p
uPAR Y869-p
WHSC1L1 Y869-p , Y1172-p , Y1197-p
YAP1 Y1092-p
Treatment:
19H6-Hu Y869-p
2-deoxyglucose Y1110-p
4-phenylpyridine Y869-p , Y1069-p , Y1092-p
8pCPT-cGMP T678-p , T693-p , S1070-p , S1071-p , Y1092-p , Y1197-p
9,10-Phenanthrenequinone T693-p , S1039-p , Y1092-p
acadesine Y1069-p , S1070-p , S1071-p , Y1092-p , Y1197-p
actinomycin_D Y869-p , Y1092-p
AEE788 Y1069-p , Y1092-p
afatinib Y1092-p , Y1110-p
AG1024 Y869-p , Y1092-p
AG1478 T693-p , Y869-p , Y1016-p , Y1069-p , Y1092-p , Y1110-p , Y1172-p , Y1197-p
AG490 Y1092-p , Y1197-p
Akt_inhibitor_VIII S229-p
alpha2-macroglobulin Y869-p , Y1092-p
amivantamab Y1092-p
amphiregulin Y1092-p , Y1197-p
androstanolone Y869-p
angiotensin Y1016-p , Y1092-p , Y1110-p , Y1172-p , Y1197-p
angiotensin_2 Y1069-p , Y1172-p
antibody Y869-p , Y1016-p , Y1092-p
API-2 S229-p
arsenite Y1110-p , Y1197-p
ATP T678-p
AZD1152 S1057-p , S1081-p
BAPTA-AM Y1069-p , Y1092-p , Y1197-p
betacellulin Y1092-p , Y1110-p , Y1197-p
BI2536 S1057-p , S1064-p
binimetinib T693-p
BIRB-0796 Y869-p , S1070-p , S1071-p , Y1092-p , Y1197-p
bisindolylmaleimide Y1092-p
BMS582949 T693-p
bradykinin Y1092-p , Y1197-p
Ca(2+) T678-p , Y869-p , Y1092-p , Y1110-p , Y1172-p , Y1197-p
calphostin_C T693-p , S695-p , S1070-p , S1071-p , S1190-p
Candidalysin T693-p , Y869-p , S1070-p , S1071-p , Y1092-p , Y1197-p
canertinib Y1092-p
capmatinib Y1197-p
cell_adhesion T693-p , Y869-p , S991-p , S1026-p , Y1069-p , Y1092-p , Y1110-p , S1166-p , Y1172-p , Y1197-p
cetuximab T693-p , Y869-p , Y1092-p , Y1197-p
cholera_toxin Y1016-p
cisplatin T693-p , Y869-p , Y1069-p , Y1092-p
CL387,785 Y869-p
compound_5 Y869-p , Y1092-p
conditioned medium Y869-p , Y1110-p
CRM197 Y869-p , Y1092-p
cryptotanshinone Y1069-p
cycloheximide Y869-p , Y1092-p
D-t-EtDO-P4 Y1092-p , Y1110-p , Y1172-p , Y1197-p
dacomitinib Y1092-p , Y1110-p
dasatinib Y869-p , Y1092-p , Y1110-p , Y1172-p , Y1197-p
depolarization Y1092-p
diesel_exhaust Y869-p , Y1016-p , Y1092-p , Y1197-p
dronabinol Y1197-p
EGF S229-p , T678-p , T693-p , S695-p , K716-ub , T725-p , K737-ub , K757-ub , Y764-p , Y801-p , K867-ub , Y869-p , K875-ub , K970-ub , Y978-p , S991-p , S995-p , Y998-p , Y1016-p , S1025-p , S1026-p , S1039-p , T1041-p , S1057-p , K1061-ub , Y1069-p , S1070-p , S1071-p , S1081-p , Y1092-p , S1104-p , Y1110-p , Y1125-p , Y1138-p , S1166-p , Y1172-p , K1179-ac , K1182-ac , K1188-ac , S1190-p , Y1197-p
EGTA Y869-p , Y1092-p , Y1110-p , Y1172-p , Y1197-p
Enkamin-E T693-p
ephrin_B1 Y1172-p , Y1197-p
erlotinib T678-p , T693-p , Y869-p , Y998-p , Y1016-p , Y1069-p , S1070-p , S1071-p , S1081-p , Y1092-p , Y1110-p , Y1138-p , S1166-p , Y1172-p , Y1197-p
FGF1 T693-p
FGF10 T693-p
FGF2 Y1110-p , Y1172-p , Y1197-p
FGF7 T693-p
fibronectin Y869-p , Y1092-p , Y1110-p , Y1172-p , Y1197-p
fMLP Y869-p , Y1016-p , Y1092-p , Y1197-p
galardin Y869-p , Y1172-p
ganglioside Y869-p , Y1092-p , Y1172-p
gastrin Y1197-p
gefitinib S768-p , Y869-p , Y1016-p , S1039-p , Y1069-p , S1070-p , S1071-p , Y1092-p , Y1110-p , Y1125-p , Y1138-p , Y1172-p , Y1197-p
genistein Y1092-p , Y1197-p
Go_6976 T678-p
Go_6983 T678-p
gomisin_A T693-p , S1070-p , S1071-p
gomisin_N T693-p , S1070-p , S1071-p
H2O2 T678-p , T693-p , S695-p , Y869-p , Y1069-p , S1070-p , S1071-p , Y1092-p , Y1197-p
HB-EGF Y1016-p , Y1069-p , Y1092-p
HDM Y1092-p
heregulin Y869-p , Y1016-p , Y1069-p
HGF Y869-p , Y1092-p , S1166-p , Y1172-p , Y1197-p
HKI-357 Y1092-p
hypoxia Y869-p , Y1110-p , Y1197-p
IGF-1 T693-p
IGF-2 Y869-p , Y1092-p
IGFBP-3 Y1092-p
IL-33 Y869-p , Y1092-p
imatinib Y1092-p , Y1197-p
INCB3619 Y1092-p , Y1197-p
INCB4298 Y1092-p
INCB8765 Y1092-p
integrin Y1092-p , Y1110-p , Y1197-p
ionizing_radiation T678-p , Y869-p , Y1016-p , Y1069-p , Y1092-p , Y1110-p , Y1197-p
ischemia T693-p , S1166-p
lapatinib S1039-p , S1042-p , S1045-p , S1064-p , Y1092-p , Y1110-p , S1166-p , Y1172-p , Y1197-p
lenvatinib Y1092-p
LL-37 Y869-p , Y1069-p
LL-8 Y869-p , Y1069-p
LPA Y1092-p , S1162-p , S1166-p
LPS Y1092-p , Y1110-p
LY294002 S229-p , Y869-p , Y1016-p , Y1092-p , Y1110-p , Y1172-p , Y1197-p
magnetic_field,_coherent Y1197-p
magnetic_field,_incoherent Y1197-p
medium change Y1197-p
metastatic potential T693-p
metformin Y1092-p
methyl-beta-cyclodextrin Y869-p , Y1016-p , Y1069-p , Y1092-p , Y1197-p
MG132 S1162-p , S1166-p
MLN8054 S1045-p
Mn(2+) Y1197-p
neratinib Y1016-p , Y1092-p
neurotensin Y869-p
nifedipine Y1092-p
nocodazole T693-p , S991-p , S995-p , S1064-p , S1081-p
osimertinib Y1092-p , Y1110-p , Y1172-p
osmotic_stress Y869-p , Y1197-p
p-Tyr T678-p
P25 Y869-p
PD153035 Y869-p , Y1069-p , Y1092-p
PD158780 Y1172-p
PD168393 Y869-p , Y1092-p , Y1110-p , Y1172-p , Y1197-p
PD173074 T693-p , Y1110-p
PD173952 Y869-p , Y1172-p
PD98059 Y869-p , Y1016-p , Y1092-p , Y1110-p , Y1172-p , Y1197-p
PDGF T678-p , T693-p , Y1197-p
peptide Y1092-p , Y1197-p
peptide inhibitor Y869-p , Y1092-p , Y1172-p
pertuzumab Y869-p
PHA-665752 Y869-p , Y1092-p
phorbol_ester T678-p , T693-p , S695-p , S1070-p , S1071-p , Y1092-p , Y1172-p , S1190-p , Y1197-p
picropodophyllin Y869-p
PP1 Y869-p , Y1092-p , Y1172-p
PP2 Y869-p , Y1016-p , Y1092-p , Y1197-p
PP3 Y869-p , Y1092-p
pressure Y869-p
progestin_R5020 Y1197-p
PTX Y1016-p
quercetin Y1092-p
RAD001 T678-p , Y1092-p
rapamycin Y1092-p
RMC-4550 Y1092-p
rociletinib Y1172-p
rottlerin Y1092-p
rucaparib S1081-p , Y1197-p
S0859 Y1016-p
saracatinib Y869-p , Y1092-p
SB202190 S229-p , T693-p , S1039-p , T1041-p , Y1172-p
SB203580 Y869-p , S1039-p , S1070-p , S1071-p , Y1092-p , Y1197-p
SB600125 T693-p
serum T693-p , S695-p , Y869-p , S1070-p , S1071-p , Y1092-p , Y1110-p , Y1172-p , Y1197-p
siRNA S229-p , T678-p , K745-m1 , Y869-p , Y1069-p , Y1092-p
SK-29 Y869-p , Y1069-p
SKI-1 Y869-p
sorafenib Y1197-p
sotrastaurin T678-p
ST1926 Y1110-p
staurosporine T678-p , T693-p , S695-p , S1070-p , S1071-p , S1190-p
streptolysin O Y869-p , Y1016-p , Y1069-p , Y1092-p , Y1197-p
Su11274 Y869-p , Y998-p , Y1016-p , Y1069-p , Y1092-p , Y1110-p , Y1125-p , Y1138-p , Y1172-p , Y1197-p
SU6656 Y869-p , Y1092-p , Y1197-p
testosterone Y1092-p
TGF-alpha Y869-p , Y1016-p , Y1069-p , Y1092-p , Y1197-p
TGF-beta Y869-p
thrombin Y1092-p
thymidine S1064-p , S1081-p
TNF T693-p , S1039-p , S1070-p , S1071-p , Y1092-p
Trametinib T693-p , Y1092-p
U0126 T693-p , Y869-p , Y1016-p , Y1092-p , Y1110-p , Y1172-p , Y1197-p
UV Y869-p , Y1016-p , Y1069-p , Y1092-p , Y1110-p , Y1125-p , Y1172-p , Y1197-p
UVB S695-p , Y869-p , Y1069-p , Y1092-p , Y1110-p
vanadate T693-p , Y869-p , S991-p , Y1016-p , S1026-p , Y1069-p , Y1092-p , Y1110-p , Y1172-p , Y1197-p
vorinostat K875-ub
wounding Y1092-p
ZM447439 S1057-p , S1081-p
Zn(2+) Y869-p , Y1092-p