Kinase, in vitro: 

An enzyme-substrate reaction that occurs in non-living experimental conditions such as a test tube. For example, a purified enzyme is reacted with a substrate protein or mixture of proteins or peptides.

P38G S459-p
 Putative in vivo kinases: 

An enzyme-substrate reaction that occurs within living cells; includes cultured cells, ex vivo samples, and intact organisms. In the case of kinases, the large number of protein kinases in intact cells makes exact identification of the responsible kinase challenging.

P38G S459-p
TAK1 S359-p
arsenite S459-p
EGF S459-p
ischemia S357-p , S359-p , S372-p
MKK6DD S459-p
phorbol_ester S459-p
pirfenidone S459-p
rapamycin S455-p
SB203580 S459-p
selumetinib S357-p , S359-p
siRNA S459-p
sorbitol S459-p
vemurafenib S357-p , S359-p