Kinase, in vitro: 

An enzyme-substrate reaction that occurs in non-living experimental conditions such as a test tube. For example, a purified enzyme is reacted with a substrate protein or mixture of proteins or peptides.

ATM S15-p , S20-p , S46-p
ATM S15-p
ATR S15-p
AurA S106-p , S215-p , S315-p
AurB S183-p , T211-p , S215-p , S269-p , T284-p
Btk S15-p
CDK1 S315-p
CDK4 R249-p
CDK5 S20-p , S46-p
CDK6 R249-p
CDK9 S33-p
Chk1 S15-p , S20-p , T387-p
Chk2 S20-p , S366-p
CK1A T18-p , S20-p
CK2B S392-p
DAPK1 S20-p
DNAPK S15-p
DYRK1A S15-p
DYRK2 S46-p
ERK1 S15-p
ERK2 S15-p , T55-p
GRK2 T55-p
GRK5 T55-p
HIPK2 S46-p
JNK1 S20-p , T81-p
JNK2 S20-p
LKB1 S15-p , S392-p
LRRK2 T304-p , T377-p
MAPKAPK5 S37-p
NEK2 S315-p
NuaK1 S15-p , S392-p
P38A S15-p , S33-p , S46-p
P38G S33-p
PAK4 S215-p
PKCD S46-p
PLK3 S20-p
PRPK S15-p
SMG1 S15-p
Src Y126-p , Y220-p
TAF1 T55-p
VRK1 T18-p
 Putative in vivo kinases: 

An enzyme-substrate reaction that occurs within living cells; includes cultured cells, ex vivo samples, and intact organisms. In the case of kinases, the large number of protein kinases in intact cells makes exact identification of the responsible kinase challenging.

AMPKA1 T18-p , S20-p
ATM S15-p , S46-p
ATR S15-p , S37-p
AurA S106-p , S215-p , S315-p
AurB S183-p , T211-p , S215-p , S269-p , T284-p
Btk S15-p
CDK1 S315-p
CDK2 S315-p
CDK4 R249-p
CDK5 S15-p , S33-p , S46-p
CDK7 S33-p , S371-p , S376-p , S378-p , S392-p
CDK9 S33-p , S315-p , S392-p
Chk1 S15-p , T18-p , S20-p , S37-p , S378-p , T387-p
Chk2 S15-p , T18-p , S20-p , S37-p , S366-p , S378-p
CK1A S20-p , S37-p
CK1D S9-p , T18-p , S20-p
CK2A1 S149-p , T150-p , T155-p , S392-p
CK2B S392-p
DAPK1 T18-p , S20-p , S269-p
DAPK3 S20-p
DNAPK S9-p , S15-p , T18-p , S20-p , S37-p , S46-p
DRAK1 S20-p
DYRK1A S15-p
DYRK2 S46-p
ERK1 S392-p
ERK2 S15-p
ERK2 S15-p , T55-p
GRK5 T55-p
GSK3B S376-p
HIPK2 S46-p
JNK1 S20-p , T81-p
JNK2 S20-p , S46-p
LKB1 S15-p , S392-p
LRRK2 T304-p , T377-p
MAPKAPK2 S20-p
MAPKAPK5 S37-p
NEK2 S315-p
P38A S15-p , S33-p , S46-p
P38G S33-p
PAK4 S215-p
PKACA S378-p
PKCA S371-p , S376-p , T377-p , S378-p
PKCD S46-p
PKR S392-p
PLK3 S20-p
PRPK S15-p
Src Y126-p , Y220-p
TAF1 T55-p
VRK1 T18-p
Phosphatases, in vitro:
CDC14A S315-p
DUSP26 S20-p , S37-p
PPM1D S15-p
PPP1CA S15-p , S37-p
PPP2CA T55-p
PPP2CB S366-p
PPP2R5C T55-p
Putative upstream phosphatases:
CDC14A S315-p
CDC14B S315-p
DUSP26 S20-p , S37-p
PPM1D S15-p
PPP1CA S15-p , S37-p
PPP2CA S37-p
PPP2CB S366-p
PPP2R5C T55-p
Regulatory protein:
Abl S392-p
ADA K373-ac , K382-ac
Akt1 S15-p
ALOX15 S15-p
AML2 S15-p
AMPKA1 S15-p , S46-p , K382-ac
AMPKA2 S46-p
ARF1 K382-ac
ASK1 S15-p , S33-p
ATM S15-p , S20-p , S37-p , S46-p , T55-p
ATR S15-p , S37-p , S46-p
axin 1 S46-p
axin 1 S46-p
BARD1 S15-p
Bcl-2 S15-p
BMI1 S15-p
BRCA1 S15-p , S20-p
CBFB K382-ac
CCDC8 K120-ac
CCNB1 S15-p , S315-p
CCNG1 S15-p
CD44 S15-p
CD74 S15-p
CDK5R1 S15-p , S33-p , S46-p
CDK5 S15-p , S33-p , S46-p
CLK2 S15-p
COPS5 T150-p , T155-p
DAXX S46-p
DEK S15-p
DNAPK S15-p
DUSP26 S9-p , S15-p , S20-p , S37-p , S315-p , S392-p
DYRK1A K382-ac
DYRK3 K382-ac
E1B, small T-antigen K320-ac
E2F1 S15-p , S20-p
EGFR S15-p
ERK1 S15-p , S392-p
ERK2 S15-p
FAAP24 S15-p
FAM189B S46-p
FANCM S15-p
FBXW7 S15-p
GJB1 K373-ac , K382-ac
HDAC1 K373-ac , K382-ac
HDAC2 K382-ac
HDAC8 K373-ac , K382-ac
HIPK2 S15-p , S46-p
HRas S15-p , S33-p , S37-p , S46-p , K382-ac
HSPA2 S15-p
Huntingtin S15-p , S46-p
ID4 K320-ac , K373-ac
IGF1R S46-p
IHPK2 S15-p
IL23A K382-ac
ING1 iso2 K373-ac , K382-ac
ING1 K382-ac
ING2 K373-ac , K382-ac
ING4 K382-ac
ING5 K120-ac , K373-ac , K382-ac
ITGA5 S15-p
ITGB3 S15-p
lamin A/C S15-p
LATS1 S15-p , S315-p
LATS2 S15-p , S315-p
LKB1 S6-p , S9-p , S15-p , T18-p , S392-p
MAPKAPK5 S37-p
MDC1 S15-p
MDM2 S15-p , S46-p , K382-ac , K386-sm
MKK3 S15-p , S37-p
MKK6 S33-p
MLL5 S15-p , S392-p
MRPL11 K382-ac
Myc S15-p , S20-p , S33-p , S37-p , S46-p
MYH11 K382-ac
MYST2 K120-ac
NBS1 S15-p , S20-p , S46-p
NEDD8 K382-ac
NKX3-1 S15-p
NPM1 S15-p
OGA K382-ac
OGT K382-ac
p16-INK4A iso5 S392-p
p16-INK4A S15-p , K120-ac
P38A S15-p , S33-p
P38B S33-p
P38G S15-p , S33-p
p53 S15-p , S20-p , K320-ac , K382-ac
p63 S15-p
PAF K382-ac
PCAF K382-ac
PDCD5 K120-ac
PHF1 S15-p , K382-ac
PIN1 S46-p
PKCD S46-p
PKM S15-p
PLA2G6 S15-p
plakophilin 2 T18-p
PLK3 S20-p
PML iso4 S46-p , K382-ac
PML S15-p , S46-p , K382-ac
POLR2A S15-p
PPM1D S15-p , S33-p , S46-p
PPP1CA S15-p , S37-p
PPP2CA S46-p , T55-p
PPP2CB S366-p
PPP2R5A T55-p
PPP2R5C S37-p , T55-p
PPP4C S15-p
RACK1 S15-p , S33-p
RASSF5 S46-p , K382-ac
RPA1 S15-p
RPL11 K382-ac
RPS3 S15-p , S33-p
SIAH1 S46-p
SIRT1 S15-p , K382-ac
SIRT2 K373-ac , K382-ac
SIRT6 S15-p
SKP2 K382-ac
small T antigen T55-p
SMARCA4 K382-ac
SMEK2 S15-p
SOCS1 S15-p
STAT5A S15-p
TAF1 T55-p
TAT K320-ac , K373-ac
Tax S15-p , S20-p
TERT S15-p , T18-p , S376-p , S392-p
TRIM29 K120-ac
TTI1 S15-p
TWIST1 S15-p , K373-ac , K382-ac , S392-p
UBC9 K386-sm
UHRF1 K120-ac
USP22 K382-ac
VRK1 T18-p
WIPF1 S15-p
ZBTB8 K320-ac , K382-ac
ZNHIT1 S15-p , S46-p
Treatment:
1,2,3-triazole-dithiocarbamate hybrid compound 3a K382-ac
11,11'-dideoxyverticillin S20-p
15d-PGJ2 S15-p , S20-p , S33-p , S37-p , T81-p , S392-p
2-deoxyglucose S6-p , S315-p
4-AN T55-p
4-AP S15-p
4-HT S15-p , S46-p
5-aza-CdR S15-p
acadesine S15-p
aciclovir S15-p
actinomycin_D S15-p , S46-p , K120-ac , K305-ac , K373-ac , K382-ac , K386-sm
adriamycin S6-p , S9-p , S15-p , T18-p , S20-p , S33-p , S37-p , S46-p , T55-p , K120-ac , T155-p , S315-p , K320-ac , K372-m1 , K373-ac , K382-ac , K386-sm , S392-p
AG1433 S15-p
AG1478 S15-p
alpha-dendrotoxin S15-p
alvocidib S15-p
amanitin S15-p
aminoflavone S15-p
aminothiazole_compound_25 S15-p
androsterone S15-p
anisomycin S392-p
anti-IgM S15-p
anti-ITGAv S15-p
anti-ITGB3 S15-p
aphidicolin S15-p
apigenin S15-p , T55-p
arsenite S392-p
As2O3 S15-p , T18-p , S20-p
asbestos S6-p , S9-p , S15-p , S20-p , S37-p , S46-p , S392-p
ascorbic_acid S15-p
AZD1152 S183-p , T211-p , S215-p
Ba(2+) S15-p
BDS-I S15-p
BEL S15-p
beta-D-(3,4-di-sinapoyl)fructofuranosyl-alpha-D-(6-sinapoyl)glucopyranoside S15-p
beta-lapachone S392-p
bleomycin S15-p , T18-p , S392-p
bortezomib S15-p , S20-p , S46-p , S392-p
BPDE S15-p , S20-p
butyrate K120-ac , K305-ac
C-1027 S15-p
C646 K382-ac
cadmium_chloride S15-p
caffeine S15-p , S20-p , S37-p , S46-p , T55-p , S366-p , T387-p , S392-p
calyculin_A S15-p , S37-p , T55-p , K386-sm
cAMP_analog S15-p , S20-p , S46-p , S392-p
camptothecin S15-p , S366-p , K373-ac , S378-p , T387-p , S392-p
catalase S15-p
Cd(2+) S15-p
Cdk2/5_inhibitor S20-p , S46-p
Cdk2_inhibitor_II S15-p , S33-p
celecoxib S15-p , S46-p
cell_adhesion S15-p
cell_detachment S46-p
CG-1521 K373-ac
chlorpromazine K382-ac
cisplatin S15-p , S20-p , S46-p , K120-ac
colforsin S6-p , S9-p , S15-p , S20-p , S37-p , S46-p , S392-p
compound_C S15-p , T55-p , K382-ac
CPT K120-ac , K373-ac , K382-ac
cycloheximide S15-p , S20-p
D4476 S20-p
DAMGO S15-p
DDATHF S6-p , S15-p , S20-p , K373-ac , K382-ac
decursin S15-p
deferoxamine S15-p , K320-ac , K382-ac , S392-p
depsipeptide T18-p , S37-p , S46-p , K373-ac , K382-ac
desferoxamine S15-p , S37-p , S46-p
development S15-p , T18-p , S376-p , S392-p
dexamethasone S6-p , S15-p , S37-p , S392-p
doxycycline S15-p , S20-p , S46-p
DPN S15-p
DRB S15-p , S392-p
DSBs S15-p
DWP0016 K382-ac
eeyarestatin_1 S15-p
EF24 S15-p
EGF S15-p
estradiol S15-p
etoposide S6-p , S15-p , S20-p , S33-p , S37-p , S46-p , K120-ac , K164-ac , K320-ac , K370-ac , K372-ac , K373-ac , K381-ac , K382-ac , S392-p
ETS S15-p
faslodex S15-p
FK866 K382-ac
fluorouracil S15-p , S392-p
genistein S15-p
ginsenoside K373-ac , K382-ac
glucose S15-p , S392-p
glucose_starvation S15-p , S46-p
Go_6976 S9-p , S15-p , S20-p , S37-p
granzyme_B S15-p , S37-p
grape_seed_extract S15-p , S20-p
GW_9662 S392-p
H2O2 S9-p , S15-p , S20-p , S33-p , S37-p , K305-ac , K320-ac , K373-ac , K382-ac , K386-sm , S392-p
heat_shock S6-p , S9-p , S15-p , S20-p , S37-p , S46-p , S392-p
heating K382-ac
herbimycin_A S15-p
HGF S392-p
high-fat diet K382-ac
high_glucose S15-p , T18-p , S20-p , T55-p , K382-ac
hydroxyurea S15-p , S37-p
hyperoxia S15-p , S20-p , S37-p , S392-p
hypertonic_buffer S15-p
hypoxia S15-p , S37-p , S46-p , S392-p
hypoxia/reoxygenation S15-p , K373-ac , K382-ac
IBMX S6-p , S9-p , S15-p , S20-p , S37-p , S46-p , S392-p
IC261 S15-p , T18-p
ICRF-193 S15-p
idarubicin S15-p , S20-p , S37-p , S46-p , S392-p
imatinib S15-p , S46-p , S392-p
ionizing_radiation S6-p , S9-p , S15-p , T18-p , S20-p , S33-p , S37-p , S46-p , T55-p , K120-ac , S269-p , K305-ac , S315-p , K320-ac , S366-p , K373-ac , S376-p , S378-p , K382-ac , T387-p , S392-p
KN-92 K120-ac
KN-93 K120-ac
KU-55933 S15-p , S20-p , S46-p , T55-p , S392-p
KU-60019 S15-p
laminar flow K320-ac , K373-ac , K382-ac
LAQ824 K382-ac
lenalidomide S46-p , T55-p
leptomycin_B S15-p , T18-p , T55-p , K382-ac
linsitinib K120-ac
LLnL S15-p , S33-p , S46-p , T81-p , S315-p
LLY-507 K370-m1
low_glucose T18-p
low_pH S15-p
LY294002 S15-p , S46-p
MBA S315-p
melatonin S15-p
melphalan S15-p
metastatic potential S315-p
metformin K382-ac
methotrexate S15-p
methylcholanthrene S15-p
MG115 K382-ac
MG132 S15-p , S20-p , S33-p , S46-p , T55-p , S149-p , T150-p , T155-p , K370-ub , K372-ub , K373-ub , K381-ub , K382-ac , K386-ub , S392-p
MI-63 S15-p , S37-p , S392-p
MIF S15-p
miR-16 S15-p
miR-34a K382-ac
mitomycin_C S15-p , S33-p , S46-p
MLN4924 S15-p
MNNG S15-p
MnTMPyP S15-p
morphine S9-p
MS275 K292-ac , K305-ac , K373-ac , K381-ac , K382-ac
Na(2)CrO(4) S15-p
NAC S15-p
NAD_zwitterion K373-ac , K382-ac
NaF S15-p
naphthoflavone S15-p
neocarzinostatin S15-p , K382-m2
NGF K382-ac
nicotinamide K120-ac , K164-ac , K370-ac , K372-ac , K373-ac , K381-ac , K382-ac , K386-ac
nicotine R249-p
nitric_oxide S15-p
nocodazole S6-p , S9-p , S15-p , T18-p , S20-p , S33-p , S37-p , S46-p , S315-p , K320-ac , K382-ac , S392-p
NSC348884 S15-p
NSC59984 T55-p
NU7441 S15-p , S392-p
nutlin-3 S15-p , S37-p , S46-p , T55-p , K120-ac , S315-p , K373-ac , K382-ac , S392-p
ODQ S15-p
okadaic_acid S15-p , S20-p , S33-p , S37-p , S46-p , T55-p , S315-p
olomoucine S15-p
osmotic_stress S33-p , K382-ac
PALA S6-p , S9-p , S15-p , T18-p , S20-p , S33-p , S37-p , S46-p , S315-p , K320-ac , K382-ac , S392-p
PD0332991 R249-p
PD153035 S15-p
PD169316 S15-p , S46-p
PD98059 S6-p , S9-p , S15-p , S20-p , T55-p , K382-ac
PGE2 S15-p , S37-p
phorbol_ester S15-p
phosphatidylcholine S15-p
pifithrin-alpha S15-p , S37-p
plicamycin S15-p
plumbagin S15-p , K320-ac , K373-ac , S392-p
polyunsaturated_fatty_acid S15-p
PP2 S15-p
PPT S15-p
PTPI S392-p
PUGNAc T155-p
quercetin S15-p
quinacrine S15-p , S392-p
quisinostat K373-ac , K382-ac
R03306 S315-p
raltitrexed S15-p
rapamycin S15-p
resveratrol S15-p , K382-ac
retinoic_acid S315-p
RGD S15-p
RITA S15-p , S46-p
rottlerin S46-p
S17834 K382-ac
SB202190 S15-p , S20-p , S33-p , S392-p
SB203580 S15-p , S20-p , S33-p , S37-p , S46-p , T81-p , K382-ac , S392-p
selenite S15-p
seliciclib S15-p , S33-p , S46-p , S315-p
selisistat K373-ac , K382-ac
serum_starvation S15-p , T18-p , S46-p , S392-p
silibinin S6-p , S15-p , S392-p
siRNA S6-p , S9-p , S15-p , T18-p , S20-p , S33-p , S37-p , S46-p , T55-p , K120-ac , R249-p , S315-p , S366-p , K370-m1 , K373-ac , K382-m1
SJG-136 S15-p , S20-p , S392-p
SN-38 S15-p
SN-50 S15-p
SNP S6-p , S9-p , S15-p , S33-p , S46-p
SOD S15-p
sorbitol S15-p
SP600125 S6-p , S15-p , S20-p , S33-p , S37-p , T81-p , K382-ac , S392-p
staurosporine S46-p
streptozotocin S149-gl , T155-p
Su11274 S392-p
T-oligo S15-p
tamoxifen S15-p
Tat S15-p , S46-p
taxol S6-p , S9-p , S15-p , T18-p , S20-p , S33-p , S37-p , S46-p , S315-p , K320-ac , K382-ac , S392-p
Tenovin-1 K382-ac
tenovin-6 K382-ac
thapsigargin S315-p , S376-p
THIF S15-p
THSG K373-ac
thymidine S315-p
tiron K120-ac
TMZ S9-p , S15-p , S20-p , S37-p , S46-p , S392-p
TNF K382-ac , S392-p
topotecan S15-p , S46-p
TRAIL S15-p
trichostatin_A K120-ac , K164-ac , K320-ac , K370-ac , K372-ac , K373-ac , K381-ac , K382-ac , K386-ac
triphala S15-p
troglitazone S392-p
tunicamycin S315-p , S376-p
U0126 S15-p , T55-p , S392-p
UCN-01 S15-p , S20-p
UV S6-p , S9-p , S15-p , T18-p , S20-p , S33-p , S37-p , S46-p , T55-p , T81-p , K120-ac , S269-p , S315-p , K320-ac , S366-p , S371-p , K372-ac , K373-ac , S378-p , K382-ac , T387-p , S392-p
UVB K382-ac
UVC S15-p , K305-ac , K382-ac
valproic acid K120-ac
valproic_acid S46-p , K382-ac
VE822 S15-p
vinorelbine S15-p , S20-p
virus infection S9-p , S15-p , S20-p , S33-p , S37-p , S46-p , T55-p , K320-ac , K373-ac , K381-ac
vorinostat K292-ac , K305-ac , K381-ac , K382-ac
VRX0466617 S15-p , S20-p
wortmannin S15-p , S20-p , S33-p , S46-p , T55-p
WR1065 T81-p
ZM447439 S315-p