Putative in vivo kinases: 

An enzyme-substrate reaction that occurs within living cells; includes cultured cells, ex vivo samples, and intact organisms. In the case of kinases, the large number of protein kinases in intact cells makes exact identification of the responsible kinase challenging.

BCKDK S337-p , S347-p
Putative upstream phosphatases:
PPM1K S337-p
Treatment:
metastatic potential S337-p , T338-p