Kinase, in vitro: 

An enzyme-substrate reaction that occurs in non-living experimental conditions such as a test tube. For example, a purified enzyme is reacted with a substrate protein or mixture of proteins or peptides.

MEK1 T183-p , Y185-p
MEK1 T183-p , Y185-p
 Putative in vivo kinases: 

An enzyme-substrate reaction that occurs within living cells; includes cultured cells, ex vivo samples, and intact organisms. In the case of kinases, the large number of protein kinases in intact cells makes exact identification of the responsible kinase challenging.

ERK2 Y185-p
ERK2 Y185-p
Lck Y185-p
MEK1 T183-p , Y185-p
MEK1 T183-p , Y185-p
MEK1 T183-p , Y185-p
MEK1 T183-p , Y185-p
Phosphatases, in vitro:
PPP2CA T183-p , Y185-p
Regulatory protein:
AIF1 T183-p , Y185-p
Akt1 T183-p , Y185-p
ALK T183-p , Y185-p
ARAF T183-p , Y185-p
ARAF T183-p , Y185-p
ARHGEF7 T183-p , Y185-p
ARRB1 T183-p , Y185-p
BAG1 T183-p , Y185-p
Bcl-10 T183-p , Y185-p
BCR-ABL1 T183-p , Y185-p
BRAF iso1 T183-p , Y185-p
BRAF T183-p , Y185-p
Brk T183-p , Y185-p
CAMK2D T183-p , Y185-p
CARD11 T183-p , Y185-p
CARD9 T183-p , Y185-p
Cbl-b T183-p , Y185-p
CBL T183-p , Y185-p
CD151 T183-p , Y185-p
CD44 T183-p , Y185-p
CD74 T183-p , Y185-p
CDC42 iso1 T183-p , Y185-p
CDC42 T183-p
CDK5R1 T183-p , Y185-p
Cot T183-p , Y185-p
Cot T183-p , Y185-p
dectin-1 T183-p , Y185-p
DLG3 T183-p , Y185-p
DOK3 T183-p , Y185-p
DRD1 T183-p , Y185-p
DUSP19 T183-p , Y185-p
DUSP3 T183-p , Y185-p
DUSP6 T183-p , Y185-p
EAR-2 T183-p , Y185-p
EGFR T183-p , Y185-p
eNOS Y185-p
ERG T183-p , Y185-p
ERK2 T183-p , Y185-p
FADD T183-p , Y185-p
FAK iso2 T183-p , Y185-p
FAK iso9 T183-p , Y185-p
FCER1A T183-p , Y185-p
Fes T183-p , Y185-p
FGFR1 T183-p , Y185-p
FGFR2 Y185-p
FLT3 Y185-p
FLT3 T183-p , Y185-p
FMR1 T183-p , Y185-p
FOXO1A T183-p , Y185-p
FOXP1 T183-p , Y185-p
G-alpha i2 T183-p , Y185-p
G-beta 1 T183-p , Y185-p
GAB2 T183-p , Y185-p
GIPC1 T183-p , Y185-p
GIT1 T183-p , Y185-p
GLRX1 T183-p , Y185-p
GRB10 T183-p , Y185-p
GRB10 T183-p , Y185-p
HePTP T183-p , Y185-p
HRas T183-p , Y185-p
ICMT T183-p , Y185-p
IGF1R T183-p , Y185-p
IL17RD T183-p , Y185-p
IRS1 T183-p , Y185-p
ITGA9 T183-p , Y185-p
JAK2 T183-p , Y185-p
JNK2 T183-p , Y185-p
KRas T183-p , Y185-p
KSR T183-p , Y185-p
LAB T183-p , Y185-p
LAT T183-p , Y185-p
MAPKAPK2 T183-p , Y185-p
MAPKAPK3 T183-p , Y185-p
MEK1 T183-p , Y185-p
MEKK1 T183-p , Y185-p
mGluR5 T183-p , Y185-p
MIEN1 T183-p , Y185-p
MRas T183-p , Y185-p
MSK1 T183-p , Y185-p
MSK1 T183-p , Y185-p
MSK2 T183-p , Y185-p
MST1 T183-p , Y185-p
neurogranin T183-p , Y185-p
NPC1 T183-p , Y185-p
NPM1 T183-p , Y185-p
NYAP2 T183-p , Y185-p
PAG T183-p , Y185-p
PAK1 T183-p , Y185-p
PAK4 T183-p
PDGFRA T183-p , Y185-p
PDK1 T183-p , Y185-p
PELI1 T183-p , Y185-p
PHLPP2 T183-p , Y185-p
PHLPP T183-p , Y185-p
PKCA T183-p , Y185-p
PKCT T183-p , Y185-p
PPP1CC T183-p , Y185-p
PRKD1 T183-p , Y185-p
PRMT5 T183-p , Y185-p
PRMT5 T183-p , Y185-p
PRMT5 T183-p , Y185-p
PTEN T183-p , Y185-p
PTP1B T183-p , Y185-p
PTPRB T183-p , Y185-p
PTPRJ T183-p , Y185-p
PTPRM T183-p , Y185-p
RAB11A T183-p , Y185-p
Rab7 T183-p , Y185-p
RAC1 T183-p , Y185-p
RAF1 T183-p , Y185-p
RAF1 T183-p , Y185-p
RAIG1 T183-p , Y185-p
Ret T183-p , Y185-p
RHOC T183-p , Y185-p
RICTOR T183-p
ROCK1 T183-p , Y185-p
SGPL1 T183-p , Y185-p
SH3BP2 T183-p , Y185-p
SHC1 iso2 T183-p , Y185-p
SHP-2 T183-p , Y185-p
Src iso1 T183-p , Y185-p
Src T183-p , Y185-p
Syk T183-p , Y185-p
syndecan-4 T183-p , Y185-p
TAK1 T183-p , Y185-p
TBK1 T183-p , Y185-p
Tel T183-p , Y185-p
TSC2 T183-p , Y185-p
UCP2 T183-p , Y185-p
VEGFR3 T183-p , Y185-p
Vinculin T183-p , Y185-p
ZAP70 T183-p , Y185-p
Treatment:
15d-PGJ2 T183-p , Y185-p
17-beta-estradiol T183-p , Y185-p
1Na-PP1 T183-p , Y185-p
22-hydroxycholesterol T183-p , Y185-p
5'-methylthioadenosine T183-p , Y185-p
8-(3-chlorostyryl) caffeine T183-p , Y185-p
9d T183-p , Y185-p
A23187 T183-p , Y185-p
acadesine T183-p , Y185-p
adriamycin T183-p , Y185-p
AG1296 T183-p , Y185-p
AG1478 T183-p , Y185-p
AG490 T183-p , Y185-p
AGEs T183-p , Y185-p
Akt-I-1 T183-p , Y185-p
Akt_activator_compound_11 T183-p , Y185-p
Akt_inhibitor_VIII T183-p , Y185-p
alloxazine T183-p , Y185-p
alpha-lipoic_acid T183-p , Y185-p
amino_acid_starvation T183-p , Y185-p
amino_acids T183-p , Y185-p
amphoterin T183-p , Y185-p
angiopoietin-1 T183-p , Y185-p
angiopoietin-2 T183-p , Y185-p
anisomycin T183-p , Y185-p
anti-CD3 T183-p , Y185-p
anti-CD3/CD28 T183-p , Y185-p
anti-CD4 T183-p , Y185-p
anti-CD8 T183-p , Y185-p
anti-Fas T183-p , Y185-p
anti-IgB T183-p , Y185-p
anti-IgE T183-p , Y185-p
anti-IgM T183-p , Y185-p
anti-ITGA4 T183-p , Y185-p
anti-ITGA6 T183-p , Y185-p
anti-ITGB3 T183-p , Y185-p
antichymotrypsin T183-p , Y185-p
antigenic stimulation T183-p , Y185-p
antitrypsin T183-p , Y185-p
aphidicolin T183-p , Y185-p
apigenin T183-p , Y185-p
apomorphine T183-p , Y185-p
atorvastatin T183-p , Y185-p
bacterial infection T183-p , Y185-p
BAPTA-AM T183-p , Y185-p
Bay61-3606 T183-p , Y185-p
BDNF T183-p , Y185-p
benzo(a)pyrene T183-p , Y185-p
beta-amyloid_40 T183-p , Y185-p
betaxolol T183-p , Y185-p
BFD-22 T183-p , Y185-p
BI-D1870 T183-p , Y185-p
bicuculline T183-p , Y185-p
BIRA766 T183-p , Y185-p
BIRB-0796 T183-p , Y185-p
bisindolylmaleimide T183-p , Y185-p
black_tea_polyphenols T183-p , Y185-p
bombesin T183-p , Y185-p
bradykinin T183-p , Y185-p
brefeldin_A Y185-p
BRL37344 T183-p , Y185-p
caffeine T183-p , Y185-p
calphostin_C T183-p , Y185-p
calyculin_A T183-p , Y185-p
cAMP_analog T183-p , Y185-p
cell_adhesion T183-p , Y185-p
cell_detachment T183-p , Y185-p
CGP77675 T183-p , Y185-p
CGS_21680 T183-p , Y185-p
chelerythrine T183-p , Y185-p
ciclopirox_olamine T183-p , Y185-p
cocaine T183-p , Y185-p
cold_water_stress T183-p , Y185-p
colforsin T183-p , Y185-p
compound_56 T183-p , Y185-p
compound_6 T183-p , Y185-p
ConA T183-p , Y185-p
curcumin T183-p , Y185-p
curdlan T183-p , Y185-p
CXCL12 T183-p , Y185-p
cyclic_stretch T183-p , Y185-p
cycloheximide T183-p , Y185-p
cytochalasin_D T183-p , Y185-p
dactolisib T183-p , Y185-p
DDA T183-p , Y185-p
depolarization T183-p , Y185-p
desmopressin T183-p , Y185-p
DETA-NONOate Y185-p
dexamethasone T183-p , Y185-p
DHPG T183-p , Y185-p
differentiation T183-p , Y185-p
DMNQ T183-p , Y185-p
DNP T183-p , Y185-p
DPCPX T183-p , Y185-p
DPDPE Y185-p
dronabinol T183-p , Y185-p
DTLET Y185-p
EDTA T183-p , Y185-p
EGF T183-p , Y185-p
EGTA T183-p , Y185-p
Epo T183-p , Y185-p
epoxomicin T183-p , Y185-p
estradiol T183-p , Y185-p
ethanol T183-p , Y185-p
ether T183-p , Y185-p
faslodex T183-p , Y185-p
fedratinib T183-p , Y185-p
FGF1 T183-p , Y185-p
FGF2 T183-p , Y185-p
fibronectin T183-p , Y185-p
fingolimod T183-p , Y185-p
fisetin T183-p , Y185-p
FL T183-p , Y185-p
fluid_shear_stress T183-p , Y185-p
food deprivation T183-p , Y185-p
G-CSF T183-p , Y185-p
GDNF T183-p , Y185-p
gefitinib T183-p , Y185-p
gelatin T183-p , Y185-p
GF109203X T183-p , Y185-p
GH T183-p , Y185-p
GLP-1 T183-p , Y185-p
glucose T183-p , Y185-p
GM-CSF T179-p , T183-p
GnRH T183-p , Y185-p
Go_6976 T183-p , Y185-p
guanosine T183-p , Y185-p
GW4869 T183-p , Y185-p
H-89 T183-p , Y185-p
H2O2 T183-p , Y185-p
haloperidol T183-p , Y185-p
heart failure T188-p
heparin sodium T183-p , Y185-p
herstatin T183-p , Y185-p
HGF T183-p , Y185-p
honokiol T183-p , Y185-p
hypertonic_buffer T183-p , Y185-p
hypoxia T183-p , Y185-p
IBMX T183-p , Y185-p
ICI-118,551 T183-p , Y185-p
IFN-alpha T183-p , Y185-p
IFN-gamma T183-p , Y185-p
IgE T183-p , Y185-p
IGF-1 T183-p , Y185-p
IGF-2 T183-p , Y185-p
IL-18 T183-p , Y185-p
IL-1b T183-p , Y185-p
IL-3 T183-p , Y185-p
IL-33 T183-p , Y185-p
IL-4 T183-p , Y185-p
IL-6 T183-p , Y185-p
IL-9 T183-p , Y185-p
imatinib T183-p , Y185-p
insulin T183-p , Y185-p , T188-p
ionomycin T183-p , Y185-p
ischemia/reperfusion T183-p , Y185-p
isoflurane T183-p
isoproterenol T183-p , Y185-p
iturelix T183-p , Y185-p
JNK_inhibitor_I T183-p , Y185-p
kainic_acid T183-p , Y185-p
ketamine T183-p
KGF Y185-p
KN-93 T183-p , Y185-p
KT5823 T183-p , Y185-p
L-744,832 T183-p , Y185-p
L-NAME T183-p , Y185-p
laminin-1 T183-p , Y185-p
leptin T183-p , Y185-p
leucine T183-p , Y185-p
levamfetamine T183-p , Y185-p
licochalcone_A T183-p , Y185-p
licochalcone_B T183-p , Y185-p
licochalcone_C T183-p , Y185-p
licochalcone_D T183-p , Y185-p
LIF T183-p , Y185-p
LIF withdrawal T183-p , Y185-p
light T183-p , Y185-p
lonafarnib T183-p , Y185-p
long-term_potentiation T183-p , Y185-p
low_glucose T183-p , Y185-p
LPA T179-p , T183-p , Y185-p
LPS T183-p , Y185-p
LY294002 T183-p , Y185-p
M-CSF T183-p , Y185-p
methotrexate T183-p , Y185-p
methyl-beta-cyclodextrin T183-p , Y185-p
methylphenidate T183-p , Y185-p
MG132 T183-p , Y185-p
midazolam T183-p , Y185-p
MIF T183-p , Y185-p
miR-181a T183-p , Y185-p
MK801 T183-p , Y185-p
MMS T183-p , Y185-p
MnTBAP T183-p , Y185-p
morphine Y185-p
MPTP T183-p , Y185-p
MRS-1523 T183-p , Y185-p
MSH T183-p , Y185-p
muramyl_dipeptide T183-p , Y185-p
NAC T183-p , Y185-p
nicotine T183-p , Y185-p
nifedipine T183-p , Y185-p
NMDA T183-p , Y185-p
nocodazole T183-p , Y185-p
nomifensine T183-p , Y185-p
NP68 T183-p , Y185-p
NSC697923 T183-p , Y185-p
NTCU T183-p , Y185-p
NVP-BKM120 T183-p , Y185-p
ODQ T183-p , Y185-p
OH-BBN T183-p , Y185-p
okadaic_acid T183-p , Y185-p
orantinib T183-p , Y185-p
OVA T183-p , Y185-p
PACAP T183-p , Y185-p
palmitate T183-p , Y185-p
Pam3CSK4 T183-p , Y185-p
papaverine T183-p , Y185-p
PAR1-activating_peptide T183-p , Y185-p
PD0325901 T183-p , Y185-p
PD169316 T183-p , Y185-p
PD184352 T183-p , Y185-p
PD90059 T183-p , Y185-p
PD98059 T183-p , Y185-p
PDGF T183-p , Y185-p
peptones T183-p , Y185-p
PGE2 T183-p , Y185-p
phorbol_ester T183-p , Y185-p
pilocarpine T183-p , Y185-p
PKC-theta_pseudosubstrate T183-p , Y185-p
PKC412 Y185-p
poly-L-lysine T183-p , Y185-p
pomegranate_wine T183-p , Y185-p
PP1 T183-p , Y185-p
PP2 T183-p , Y185-p
prazosin T183-p , Y185-p
progestin_R5020 T183-p , Y185-p
propofol T183-p
propranolol T183-p , Y185-p
PTH(1-34) Y185-p
PTX T183-p , Y185-p
racepinefrine T183-p , Y185-p
Raf1_kinase_inhibitor_I T183-p , Y185-p
RANKL T183-p , Y185-p
rapamycin T183-p , Y185-p
refeeding T183-p , Y185-p
restraint stress T183-p , Y185-p
resveratrol T183-p , Y185-p
retinoic_acid T183-p , Y185-p
RGD T183-p , Y185-p
RGE T183-p , Y185-p
rimonabant T183-p , Y185-p
rolipram T183-p , Y185-p
rosiglitazone T183-p , Y185-p
rottlerin T183-p , Y185-p
S107 T183-p , Y185-p
SB202190 T183-p , Y185-p
SB203580 T183-p , Y185-p
SCF T183-p , Y185-p
SCH_23390 T183-p , Y185-p
seliciclib T183-p , Y185-p
semaxanib T183-p , Y185-p
serum T183-p , Y185-p
serum_withdrawal T183-p , Y185-p
silibinin T183-p , Y185-p
silymarin T183-p , Y185-p
siRNA T183-p , Y185-p
SKF82958 T183-p , Y185-p
SL0101 T183-p , Y185-p
SL327 T183-p , Y185-p
SMI11293 T183-p , Y185-p
sorbitol T183-p , Y185-p
SP600125 T183-p , Y185-p
sphingomyelin T183-p , Y185-p
sphingosine_1-phosphate T183-p , Y185-p
SPT T183-p , Y185-p
staurosporine T183-p , Y185-p
streptozotocin T183-p , Y185-p
SU5402 T183-p , Y185-p
SU6656 T183-p , Y185-p
sunitinib T183-p , Y185-p
TAK1_inhibitor T183-p , Y185-p
TCAP-1 T183-p , Y185-p
TCDD T183-p , Y185-p
TDZD-8 T183-p , Y185-p
TGF-alpha T183-p , Y185-p
TGF-beta T183-p , Y185-p
Theophylline T183-p , Y185-p
thrombin T183-p , Y185-p
thrombospondin T183-p , Y185-p
TNF T183-p , Y185-p
Torin1 T183-p , Y185-p
triciribine T183-p , Y185-p
TTX T183-p , Y185-p
TUG-891 T183-p , Y185-p
tunicamycin Y185-p
U0126 T183-p , Y185-p
urethane T183-p , Y185-p
UV T183-p , Y185-p
vasopressin T183-p , Y185-p
VEGF T183-p , Y185-p
visual experience T183-p , Y185-p
vitronectin T183-p , Y185-p
WIN T183-p , Y185-p
wortmannin T183-p , Y185-p
Y27632 T183-p , Y185-p
YM-254890 T183-p , Y185-p
yohimbine T183-p , Y185-p
Zn(2+) T183-p , Y185-p
zymosan T183-p , Y185-p