Other Species / Isoforms
  MEF2C (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

  HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
K4
____MGRKKIQITRI
1 1
MEF2C (human) ____MGRKKIQITRI K4
MEF2C iso3 (human) ____MGRKKIQITRI K4
MEF2C iso6 (human) ____MGRKKIQITRI K4
MEF2C (mouse) ____MGRkKIQITRI K4-ac
MEF2C iso4 (mouse) ____MGRKKIQITRI K4
MEF2C (rat) ____MGRKKIQITRI K4
T20
DERNRQVTFTKRKFG
1 0
MEF2C (human) DERNRQVTFTKRKFG T20
MEF2C iso3 (human) DERNRQVTFTKRKFG T20
MEF2C iso6 (human) DERNRQVTFTKRKFG T20
MEF2C (mouse) DERNRQVtFTKRKFG T20-p
MEF2C iso4 (mouse) DERNRQVTFTKRKFG T20
MEF2C (rat) DERNRQVTFTKRKFG T20
S59
NKLFQYASTDMDKVL
2 0
MEF2C (human) NKLFQYASTDMDKVL S59
MEF2C iso3 (human) NKLFQYAsTDMDKVL S59-p
MEF2C iso6 (human) NKLFQYASTDMDKVL S59
MEF2C (mouse) NKLFQYAsTDMDKVL S59-p
MEF2C iso4 (mouse) NKLFQYASTDMDKVL S59
MEF2C (rat) NKLFQYASTDMDKVL S59
T80-p
NEPHESRtNsDIVET
Upstream
Downstream
1 1
Effects on Modified Protein
  • molecular association, regulation
Effects on Biological Processes:
  • cell differentiation, induced
Kinase, in vitro:
  • caMLCK (human)
Putative in vivo kinases:
  • skMLCK (human)
Treatment
  • ML-7
MEF2C (human) NEPHESRtNsDIVET T80-p
MEF2C iso3 (human) NEPHESRTNSDIVET T80
MEF2C iso6 (human) NEPHESRTNSDIVEA T80
MEF2C (mouse) NEPHESRTNsDIVET T80
MEF2C iso4 (mouse) NEPHESRTNSDIVEA T80
MEF2C (rat) NEPHESRTNSDIVEA T80
S82-p
PHESRtNsDIVETLR
0 2
MEF2C (human) PHESRtNsDIVETLR S82-p
MEF2C iso3 (human) PHESRTNSDIVETLR S82
MEF2C iso6 (human) PHESRTNSDIVEALN S82
MEF2C (mouse) PHESRTNsDIVETLR S82-p
MEF2C iso4 (mouse) PHESRTNSDIVEALN S82
MEF2C (rat) PHESRTNSDIVEALN S82
S98-p
KGLNGCDsPDPDADD
1 12
MEF2C (human) KGLNGCDsPDPDADD S98-p
MEF2C iso3 (human) KGLNGCDSPDPDADD S98
MEF2C iso6 (human) gap -
MEF2C (mouse) KGLNGCDsPDPDADD S98-p
MEF2C iso4 (mouse) gap -
MEF2C (rat) gap -
S106-p
PDPDADDsVGHsPES
0 6
MEF2C (human) PDPDADDsVGHsPES S106-p
MEF2C iso3 (human) PDPDADDSVGHSPES S106
MEF2C iso6 (human) gap -
MEF2C (mouse) PDPDADDsVGHsPES S106-p
MEF2C iso4 (mouse) gap -
MEF2C (rat) gap -
S110-p
ADDsVGHsPESEDkY
1 7
MEF2C (human) ADDsVGHsPESEDkY S110-p
MEF2C iso3 (human) ADDSVGHSPESEDKY S110
MEF2C iso6 (human) gap -
MEF2C (mouse) ADDsVGHsPESEDKY S110-p
MEF2C iso4 (mouse) gap -
MEF2C (rat) gap -
K116-ac
HsPESEDkYRkINED
Upstream
Downstream
1 0
Effects on Modified Protein
  • molecular association, regulation
Effects on Biological Processes:
  • cell differentiation, induced
  • transcription, induced
Treatment
  • siRNA
MEF2C (human) HsPESEDkYRkINED K116-ac
MEF2C iso3 (human) HSPESEDKYRKINED K116
MEF2C iso6 (human) gap -
MEF2C (mouse) HsPESEDKYRKINED K116
MEF2C iso4 (mouse) gap -
MEF2C (rat) gap -
K119-ac
ESEDkYRkINEDIDL
Upstream
Downstream
1 0
Effects on Modified Protein
  • molecular association, regulation
Effects on Biological Processes:
  • cell differentiation, induced
  • transcription, induced
Treatment
  • siRNA
MEF2C (human) ESEDkYRkINEDIDL K119-ac
MEF2C iso3 (human) ESEDKYRKINEDIDL K119
MEF2C iso6 (human) gap -
MEF2C (mouse) ESEDKYRKINEDIDL K119
MEF2C iso4 (mouse) gap -
MEF2C (rat) gap -
-
gap
0 2
MEF2C (human) gap -
MEF2C iso3 (human) gap -
MEF2C iso6 (human) NKKENKGCEsPDPDS C96
MEF2C (mouse) gap -
MEF2C iso4 (mouse) NKKENKGsEsPDPDS S96-p
MEF2C (rat) NKKEHRGCDsPDPDT C96
-
gap
0 9
MEF2C (human) gap -
MEF2C iso3 (human) gap -
MEF2C iso6 (human) KENKGCEsPDPDSSy S98-p
MEF2C (mouse) gap -
MEF2C iso4 (mouse) KENKGsEsPDPDSSY S98-p
MEF2C (rat) KEHRGCDsPDPDTSY S98-p
-
gap
0 1
MEF2C (human) gap -
MEF2C iso3 (human) gap -
MEF2C iso6 (human) sPDPDSSyALtPRTE Y105-p
MEF2C (mouse) gap -
MEF2C iso4 (mouse) sPDPDSSYALtPRTE Y105
MEF2C (rat) sPDPDTSYVLtPHTE Y105
-
gap
0 7
MEF2C (human) gap -
MEF2C iso3 (human) gap -
MEF2C iso6 (human) PDSSyALtPRTEEKY T108-p
MEF2C (mouse) gap -
MEF2C iso4 (mouse) PDSSYALtPRTEEKY T108-p
MEF2C (rat) PDTSYVLtPHTEEKY T108-p
S181-p
HPSLQRNsMsPGVTH
0 1
MEF2C (human) HPSLQRNsMsPGVTH S181-p
MEF2C iso3 (human) HPSLQRNSMSPGVTH S181
MEF2C iso6 (human) HPSLQRNSMSPGVTH S179
MEF2C (mouse) HPSLQRNSMsPGVTH S181
MEF2C iso4 (mouse) HPSLQRNSMSPGVTH S179
MEF2C (rat) gap -
S183-p
SLQRNsMsPGVTHRP
1 2
MEF2C (human) SLQRNsMsPGVTHRP S183-p
MEF2C iso3 (human) SLQRNSMSPGVTHRP S183
MEF2C iso6 (human) SLQRNSMSPGVTHRP S181
MEF2C (mouse) SLQRNSMsPGVTHRP S183-p
MEF2C iso4 (mouse) SLQRNSMSPGVTHRP S181
MEF2C (rat) ATLHRNVsPGAPQRP S192-p
S192
GVTHRPPSAGNTGGL
0 1
MEF2C (human) GVTHRPPSAGNTGGL S192
MEF2C iso3 (human) GVTHRPPSAGNTGGL S192
MEF2C iso6 (human) GVTHRPPSAGNTGGL S190
MEF2C (mouse) GVTHRPPsAGNTGGL S192-p
MEF2C iso4 (mouse) GVTHRPPSAGNTGGL S190
MEF2C (rat) GAPQRPPSTGSAGGM S201
S206
LMGGDLTSGAGTSAG
0 1
MEF2C (human) LMGGDLTSGAGTSAG S206
MEF2C iso3 (human) LMGGDLTSGAGTSAG S206
MEF2C iso6 (human) LMGGDLTSGAGTSAG S204
MEF2C (mouse) LMGGDLTsGAGTSAG S206-p
MEF2C iso4 (mouse) LMGGDLTSGAGTSAG S204
MEF2C (rat) TTDLTVPNGAGNGPV N218
S222-p
GYGNPRNsPGLLVsP
Upstream
Downstream
1 34
Effects on Biological Processes:
  • apoptosis, inhibited
  • cell cycle regulation
  • transcription, induced
Kinase, in vitro:
  • MARK3 (human)
MEF2C (human) GYGNPRNsPGLLVsP S222-p
MEF2C iso3 (human) GYGNPRNSPGLLVSP S222
MEF2C iso6 (human) GYGNPRNSPGLLVSP S220
MEF2C (mouse) GYGNPRNsPGLLVsP S222-p
MEF2C iso4 (mouse) GYGNPRNSPGLLVSP S220
MEF2C (rat) GFVDSRAsPNLIGNT S235-p
S228-p
NsPGLLVsPGNLNkN
0 12
MEF2C (human) NsPGLLVsPGNLNkN S228-p
MEF2C iso3 (human) NSPGLLVSPGNLNKN S228
MEF2C iso6 (human) NSPGLLVSPGNLNKN S226
MEF2C (mouse) NsPGLLVsPGNLNKN S228-p
MEF2C iso4 (mouse) NSPGLLVSPGNLNKN S226
MEF2C (rat) AsPNLIGNTGANSVG N241
K234-ac
VsPGNLNkNMQAksP
Upstream
Downstream
1 1
Effects on Modified Protein
  • molecular association, regulation
Effects on Biological Processes:
  • cell differentiation, induced
  • transcription, induced
Treatment
  • siRNA
MEF2C (human) VsPGNLNkNMQAksP K234-ac
MEF2C iso3 (human) VSPGNLNKNMQAKSP K234
MEF2C iso6 (human) VSPGNLNKNMQAKSP K232
MEF2C (mouse) VsPGNLNKNIQAKsP K234
MEF2C iso4 (mouse) VSPGNLNKNIQAKSP K232
MEF2C (rat) TGANSVGkVMPTKsP K249-ac
K239-ac
LNkNMQAksPPPMNL
Upstream
Downstream
1 0
Effects on Modified Protein
  • molecular association, regulation
Effects on Biological Processes:
  • cell differentiation, induced
  • transcription, induced
Treatment
  • siRNA
MEF2C (human) LNkNMQAksPPPMNL K239-ac
MEF2C iso3 (human) LNKNMQAKSPPPMNL K239
MEF2C iso6 (human) LNKNMQAKSPPPMNL K237
MEF2C (mouse) LNKNIQAKsPPPMNL K239
MEF2C iso4 (mouse) LNKNIQAKSPPPMNL K237
MEF2C (rat) VGkVMPTKsPPPPGG K254
S240-p
NkNMQAksPPPMNLG
Upstream
1 20
Treatment
  • dasatinib
MEF2C (human) NkNMQAksPPPMNLG S240-p
MEF2C iso3 (human) NKNMQAKSPPPMNLG S240
MEF2C iso6 (human) NKNMQAKSPPPMNLG S238
MEF2C (mouse) NKNIQAKsPPPMNLG S240-p
MEF2C iso4 (mouse) NKNIQAKSPPPMNLG S238
MEF2C (rat) GkVMPTKsPPPPGGG S255-p
R251
MNLGMNNRkPDLRVL
0 1
MEF2C (human) MNLGMNNRkPDLRVL R251
MEF2C iso3 (human) MNLGMNNRKPDLRVL R251
MEF2C iso6 (human) MNLGMNNRKPDLRVL R249
MEF2C (mouse) MNLGMNNrKPDLRVL R251-m1
MEF2C iso4 (mouse) MNLGMNNRKPDLRVL R249
MEF2C (rat) GSVGMNSRKPDLRVV R269
K252-ac
NLGMNNRkPDLRVLI
Upstream
Downstream
1 0
Effects on Modified Protein
  • molecular association, regulation
Effects on Biological Processes:
  • cell differentiation, induced
  • transcription, induced
Treatment
  • siRNA
MEF2C (human) NLGMNNRkPDLRVLI K252-ac
MEF2C iso3 (human) NLGMNNRKPDLRVLI K252
MEF2C iso6 (human) NLGMNNRKPDLRVLI K250
MEF2C (mouse) NLGMNNrKPDLRVLI K252
MEF2C iso4 (mouse) NLGMNNRKPDLRVLI K250
MEF2C (rat) SVGMNSRKPDLRVVI K270
K264-ac
VLIPPGSkNTMPSVS
Upstream
Downstream
1 0
Effects on Modified Protein
  • molecular association, regulation
Effects on Biological Processes:
  • cell differentiation, induced
  • transcription, induced
Treatment
  • siRNA
MEF2C (human) VLIPPGSkNTMPSVS K264-ac
MEF2C iso3 (human) VLIPPGSKNTMPSVS K264
MEF2C iso6 (human) VLIPPGSKNTMPSVN K262
MEF2C (mouse) VLIPPGSKNTMPSVS K264
MEF2C iso4 (mouse) VLIPPGSKNTMPSVN K262
MEF2C (rat) VVIPPSSKGMMPPLN K282
T293
QSAQSLATPVVSVAT
2 0
MEF2C (human) QSAQSLATPVVSVAT T293
MEF2C iso3 (human) QSAQSLAtPVVSVAt T293-p
MEF2C iso6 (human) QSAQSLATPVVSVAT T283
MEF2C (mouse) QSAQSLATPVVSVAT T293
MEF2C iso4 (mouse) QSAQSLATPVVSVAT T283
MEF2C (rat) QATQPLATPVVSVTT T304
T300
TPVVSVATPTLPGQG
2 0
MEF2C (human) TPVVSVATPTLPGQG T300
MEF2C iso3 (human) tPVVSVAtPTLPGQG T300-p
MEF2C iso6 (human) TPVVSVATPTLPGQG T290
MEF2C (mouse) TPVVSVATPTLPGQG T300
MEF2C iso4 (mouse) TPVVSVATPTLPGQG T290
MEF2C (rat) TPVVSVTTPSLPPQG T311
K391-sm
STQSLNIkSEPVsPP
Upstream
Downstream
1 0
Effects on Biological Processes:
  • transcription, inhibited
Regulatory protein:
  • PIAS2 (human)
MEF2C (human) STQSLNIkSEPVsPP K391-sm
MEF2C iso3 (human) gap -
MEF2C iso6 (human) STQSLNIKSEPVSPP K381
MEF2C (mouse) STQSLSIKSEPVsPP K391
MEF2C iso4 (mouse) gap -
MEF2C (rat) TNQNINIKTEPISPP K395
S396-p
NIkSEPVsPPRDRTT
Upstream
Downstream
3 9
Effects on Modified Protein
  • protein processing
  • sumoylation
Effects on Biological Processes:
  • transcription, induced
Kinase, in vitro:
  • CDK1 (human)
MEF2C (human) NIkSEPVsPPRDRTT S396-p
MEF2C iso3 (human) gap -
MEF2C iso6 (human) NIKSEPVSPPRDRTT S386
MEF2C (mouse) SIKSEPVsPPRDRTT S396-p
MEF2C iso4 (mouse) gap -
MEF2C (rat) NIKTEPISPPRDRMT S400
S419-p
TRHEAGRsPVDSLSS
3 2
MEF2C (human) TRHEAGRsPVDSLSS S419-p
MEF2C iso3 (human) TRHEAGRsPVDSLSS S387-p
MEF2C iso6 (human) TRHEAGRSPVDSLSS S409
MEF2C (mouse) TRHEAGRSPVDSLSS S420
MEF2C iso4 (mouse) TRHEAGRSPVDSLSS S378
MEF2C (rat) PRQEMGRSPVDSLSS S441
S445-p
DHRNEFHsPIGLTRP
0 3
MEF2C (human) DHRNEFHsPIGLTRP S445-p
MEF2C iso3 (human) DHRNEFHSPIGLTRP S413
MEF2C iso6 (human) DHRNEFHSPIGLTRP S435
MEF2C (mouse) DHRNEFHSPIGLTRP S446
MEF2C iso4 (mouse) DHRNEFHSPIGLTRP S404
MEF2C (rat) DPRGDFHSPIVLGRP S467
S453-p
PIGLTRPsPDEREsP
0 2
MEF2C (human) PIGLTRPsPDEREsP S453-p
MEF2C iso3 (human) PIGLTRPSPDERESP S421
MEF2C iso6 (human) PIGLTRPSPDERESP S443
MEF2C (mouse) PIGLTRPSPDERESP S454
MEF2C iso4 (mouse) PIGLTRPSPDERESP S412
MEF2C (rat) IVLGRPPNAEDREsP N476
S459-p
PsPDEREsPsVKRMR
0 4
MEF2C (human) PsPDEREsPsVKRMR S459-p
MEF2C iso3 (human) PSPDERESPSVKRMR S427
MEF2C iso6 (human) PSPDERESPSVKRMR S449
MEF2C (mouse) PSPDERESPsVKRMR S460
MEF2C iso4 (mouse) PSPDERESPSVKRMR S418
MEF2C (rat) PNAEDREsPSVkRMR S482-p
S461-p
PDEREsPsVKRMRLS
0 3
MEF2C (human) PDEREsPsVKRMRLS S461-p
MEF2C iso3 (human) PDERESPSVKRMRLS S429
MEF2C iso6 (human) PDERESPSVKRMRLS S451
MEF2C (mouse) PDERESPsVKRMRLs S462-p
MEF2C iso4 (mouse) PDERESPSVKRMRLS S420
MEF2C (rat) AEDREsPSVkRMRMD S484
K463
EREsPsVKRMRLSEG
0 1
MEF2C (human) EREsPsVKRMRLSEG K463
MEF2C iso3 (human) ERESPSVKRMRLSEG K431
MEF2C iso6 (human) ERESPSVKRMRLSEG K453
MEF2C (mouse) ERESPsVKRMRLsEG K464
MEF2C iso4 (mouse) ERESPSVKRMRLSEG K422
MEF2C (rat) DREsPSVkRMRMDTW K486-ac
S468
sVKRMRLSEGWAT__
0 1
MEF2C (human) sVKRMRLSEGWAT__ S468
MEF2C iso3 (human) SVKRMRLSEGWAT__ S436
MEF2C iso6 (human) SVKRMRLSEGWAT__ S458
MEF2C (mouse) sVKRMRLsEGWAT__ S469-p
MEF2C iso4 (mouse) SVKRMRLSEGWAT__ S427
MEF2C (rat) gap -