Other Species / Isoforms
  HSP27 (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

 HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
R5-m1
___MTERrVPFsLLr
0 2
HSP27 (human) ___MTERrVPFsLLr R5-m1
HSP27 (mouse) ___MTERRVPFsLLr R5
HSP27 (rat) ___MTERRVPFsLLR R5
HSP27 (pig) ___MTERRVPFSLLR R5
HSP27 (hamster) ___MTERRVPFSLLR R5
HSP27 (chicken) ___MAERRVPFTFLT R5
HSP27 (dog) ___MTERRVPFSLLR R5
HSP27 (cow) ___MAERRVPFSLLR R5
S9-p
TERrVPFsLLrGPsW
1 8
HSP27 (human) TERrVPFsLLrGPsW S9-p
HSP27 (mouse) TERRVPFsLLrsPsW S9-p
HSP27 (rat) TERRVPFsLLRsPsW S9-p
HSP27 (pig) TERRVPFSLLRSPSW S9
HSP27 (hamster) TERRVPFSLLRSPsW S9
HSP27 (chicken) AERRVPFTFLTSPsW T9
HSP27 (dog) TERRVPFSLLRSPsW S9
HSP27 (cow) AERRVPFSLLRGPSW S9
R12-m1
rVPFsLLrGPsWDPF
0 36
HSP27 (human) rVPFsLLrGPsWDPF R12-m1
HSP27 (mouse) RVPFsLLrsPsWEPF R12-m1
HSP27 (rat) RVPFsLLRsPsWEPF R12
HSP27 (pig) RVPFSLLRSPSWDPF R12
HSP27 (hamster) RVPFSLLRSPsWEPF R12
HSP27 (chicken) RVPFTFLTSPsWEPF T12
HSP27 (dog) RVPFSLLRSPsWDPF R12
HSP27 (cow) RVPFSLLRGPSWDPF R12
G13
VPFsLLrGPsWDPFr
0 7
HSP27 (human) VPFsLLrGPsWDPFr G13
HSP27 (mouse) VPFsLLrsPsWEPFR S13-p
HSP27 (rat) VPFsLLRsPsWEPFR S13-p
HSP27 (pig) VPFSLLRSPSWDPFR S13
HSP27 (hamster) VPFSLLRSPsWEPFR S13
HSP27 (chicken) VPFTFLTSPsWEPFR S13
HSP27 (dog) VPFSLLRSPsWDPFR S13
HSP27 (cow) VPFSLLRGPSWDPFR G13
S15-p
FsLLrGPsWDPFrDW
Upstream
Downstream
40 106
HSP27 (human)
S15-p
Effects on Modified Protein
  • molecular association, regulation
  • phosphorylation
  • protein conformation
  • protein degradation
  • protein stabilization
  • sumoylation
Effects on Biological Processes:
  • apoptosis, altered
  • apoptosis, inhibited
  • cell growth, altered
  • cytoskeletal reorganization
  • transcription, altered
Kinase, in vitro:
  • MAPKAPK2 (human)
  • PKG1 iso2 (human)
Treatment
  • adriamycin
  • ADT
  • arsenite
  • bacterial infection
  • cisplatin
  • D3T
  • dasatinib
  • EGF
  • fluorouracil
  • IL-1b
  • ischemia
  • lapatinib
  • LRRK2-IN-1
  • menadione
  • MG132_withdrawal
  • MK2-I
  • mutation
  • OSU-03012
  • SB202190
  • SB203580
  • thiolutin
  • thrombin
  • U0126
  • ZK-Thiazolidinone
HSP27 (human) FsLLrGPsWDPFrDW S15-p
HSP27 (mouse) FsLLrsPsWEPFRDW S15-p
HSP27 (rat) FsLLRsPsWEPFRDW S15-p
HSP27 (pig) FSLLRSPSWDPFRDW S15
HSP27 (hamster) FSLLRSPsWEPFRDW S15-p
HSP27 (chicken) FTFLTSPsWEPFRDW S15-p
HSP27 (dog) FSLLRSPsWDPFRDW S15-p
HSP27 (cow) FSLLRGPSWDPFRDW S15
R20-m1
GPsWDPFrDWyPHsR
0 2
HSP27 (human) GPsWDPFrDWyPHsR R20-m1
HSP27 (mouse) sPsWEPFRDWYPAHS R20
HSP27 (rat) sPsWEPFRDWYPAHs R20
HSP27 (pig) SPSWDPFRDWYPAHS R20
HSP27 (hamster) SPsWEPFRDWYPAHS R20
HSP27 (chicken) SPsWEPFRDWYHGSR R20
HSP27 (dog) SPsWDPFRDWYPAHS R20
HSP27 (cow) GPSWDPFRDWYPAHS R20
Y23-p
WDPFrDWyPHsRLFD
0 13
HSP27 (human) WDPFrDWyPHsRLFD Y23-p
HSP27 (mouse) WEPFRDWYPAHSRLF Y23
HSP27 (rat) WEPFRDWYPAHsRLF Y23
HSP27 (pig) WDPFRDWYPAHSRLF Y23
HSP27 (hamster) WEPFRDWYPAHSRLF Y23
HSP27 (chicken) WEPFRDWYHGSRLFD Y23
HSP27 (dog) WDPFRDWYPAHSRLF Y23
HSP27 (cow) WDPFRDWYPAHSRLF Y23
S26-p
FrDWyPHsRLFDQAF
0 3
HSP27 (human) FrDWyPHsRLFDQAF S26-p
HSP27 (mouse) RDWYPAHSRLFDQAF S27
HSP27 (rat) RDWYPAHsRLFDQAF S27-p
HSP27 (pig) RDWYPAHSRLFDQAF S27
HSP27 (hamster) RDWYPAHSRLFDQAF S27
HSP27 (chicken) FRDWYHGSRLFDQSF S26
HSP27 (dog) RDWYPAHSRLFDQAF S27
HSP27 (cow) RDWYPAHSRLFDQAF S27
R37-m1
DQAFGLPrLPEEWSQ
0 2
HSP27 (human) DQAFGLPrLPEEWSQ R37-m1
HSP27 (mouse) DQAFGVPRLPDEWSQ R38
HSP27 (rat) DQAFGVPrFPDEWSQ R38-m1
HSP27 (pig) DQAFGLPRLPEEWSQ R38
HSP27 (hamster) DQAFGVPRLPDEWSQ R38
HSP27 (chicken) DQSFGMPHIPEDWYK H37
HSP27 (dog) DQAFGLPRLPEEWAQ R38
HSP27 (cow) DQAFGLPRLPEEWSQ R38
Y54-p
GGSSWPGyVrPLPPA
0 4
HSP27 (human) GGSSWPGyVrPLPPA Y54-p
HSP27 (mouse) SAAGWPGYVRPLPAA Y55
HSP27 (rat) SSAGWPGYVRPLPAA Y55
HSP27 (pig) SHSGWPGYVRPLPPP Y55
HSP27 (hamster) SAAGWPGYVRPLPAA Y55
HSP27 (chicken) SGSAWPGYFRLLPSE Y54
HSP27 (dog) GHSGWPGYVRPIPPA Y55
HSP27 (cow) SHSGWPGYVRALPAA Y55
R56-m1
SSWPGyVrPLPPAAI
0 2
HSP27 (human) SSWPGyVrPLPPAAI R56-m1
HSP27 (mouse) AGWPGYVRPLPAATA R57
HSP27 (rat) AGWPGYVRPLPAATA R57
HSP27 (pig) SGWPGYVRPLPPPAI R57
HSP27 (hamster) AGWPGYVRPLPAATA R57
HSP27 (chicken) SAWPGYFRLLPSESA R56
HSP27 (dog) SGWPGYVRPIPPAVE R57
HSP27 (cow) SGWPGYVRALPAAAI R57
S65-p
LPPAAIEsPAVAAPA
Upstream
0 22
Treatment
  • LRRK2-IN-1
  • nocodazole
  • selumetinib
  • vemurafenib
  • ZK-Thiazolidinone
HSP27 (human) LPPAAIEsPAVAAPA S65-p
HSP27 (mouse) gap -
HSP27 (rat) gap -
HSP27 (pig) gap -
HSP27 (hamster) gap -
HSP27 (chicken) LPSESALLPAPGSPY L65
HSP27 (dog) gap -
HSP27 (cow) gap -
-
gap
0 1
HSP27 (human) gap -
HSP27 (mouse) AEGPAAVtLAAPAFs T71-p
HSP27 (rat) AEGPAAVTLARPAFS T71
HSP27 (pig) gap -
HSP27 (hamster) AEGPAAVALAAPLAA A71
HSP27 (chicken) gap -
HSP27 (dog) VEGPAAAAAAAAPAY A70
HSP27 (cow) gap -
Y73-p
PAVAAPAysRALsRQ
0 13
HSP27 (human) PAVAAPAysRALsRQ Y73-p
HSP27 (mouse) VtLAAPAFsRALNRQ F77
HSP27 (rat) VTLARPAFSRALNRQ F77
HSP27 (pig) AAVAAPAYSRLLSRQ Y75
HSP27 (hamster) APLAAPAFHRALNRQ F81
HSP27 (chicken) LPAPGSPYGRALsEL Y72
HSP27 (dog) AAAAAPAYsRALSRQ Y77
HSP27 (cow) AAIEGPAYNRALSRQ Y69
S74-p
AVAAPAysRALsRQL
1 5
HSP27 (human) AVAAPAysRALsRQL S74-p
HSP27 (mouse) tLAAPAFsRALNRQL S78-p
HSP27 (rat) TLARPAFSRALNRQL S78
HSP27 (pig) AVAAPAYSRLLSRQL S76
HSP27 (hamster) PLAAPAFHRALNRQL H82
HSP27 (chicken) PAPGSPYGRALsELS G73
HSP27 (dog) AAAAPAYsRALSRQL S78-p
HSP27 (cow) AIEGPAYNRALSRQL N70
S78-p
PAysRALsRQLssGV
Upstream
Downstream
26 53
HSP27 (human)
S78-p
Effects on Modified Protein
  • activity, induced
  • intracellular localization
  • molecular association, regulation
  • phosphorylation
  • protein conformation
  • protein degradation
  • sumoylation
  • ubiquitination
Effects on Biological Processes:
  • apoptosis, altered
  • apoptosis, inhibited
  • cell cycle regulation
  • cell growth, altered
  • cytoskeletal reorganization
  • transcription, altered
Kinase, in vitro:
  • MAPKAPK2 (human)
  • PKACA (human)
  • PKG1 iso2 (human)
Putative in vivo kinases:
  • P70S6KB (human)
Regulatory protein:
  • AR (human)
  • MAPKAPK2 (human)
  • P38A (human)
Treatment
  • 5-iodotubercidin
  • ACh
  • adriamycin
  • ADT
  • ara-a
  • arsenite
  • bicalutamide
  • calyculin_A
  • cisplatin
  • D3T
  • diclofenac
  • FGF2
  • H2O2
  • heat_shock
  • heregulin
  • IL-1b
  • menadione
  • metribolone
  • mutation
  • nerve_damage
  • nocodazole
  • OSU-03012
  • PD98059
  • phorbol_ester
  • S-diclofenac
  • S-sulindac
  • S-valproate
  • SB202190
  • SB203347
  • SB203580
  • serum
  • siRNA
  • sodium_hydrosulfide
  • SP600125
  • spermine-NONOate
  • sulindac
  • taxol
  • thiolutin
  • thrombin
  • TNF
  • valproic acid
HSP27 (human) PAysRALsRQLssGV S78-p
HSP27 (mouse) PAFsRALNRQLssGV N82
HSP27 (rat) PAFSRALNRQLssGV N82
HSP27 (pig) PAYSRLLSRQLsSGV S80
HSP27 (hamster) PAFHRALNRQLsSGV N86
HSP27 (chicken) SPYGRALsELSsGIS S77-p
HSP27 (dog) PAYsRALSRQLsSGV S82
HSP27 (cow) PAYNRALSRQLsSGV S74
S82-p
RALsRQLssGVsEIr
Upstream
Downstream
57 388
HSP27 (human)
S82-p
HSP27 (mouse)
S86-p
HSP27 (rat)
S86-p
HSP27 (hamster)
S90-p
HSP27 (dog)
S86-p
Effects on Modified Protein
  • activity, induced
  • intracellular localization
  • molecular association, regulation
  • phosphorylation
  • protein conformation
  • protein degradation
  • sumoylation
  • ubiquitination
Effects on Biological Processes:
  • apoptosis, altered
  • apoptosis, inhibited
  • cell growth, altered
  • cytoskeletal reorganization
  • transcription, altered
Kinase, in vitro:
  • Akt1 (human)
  • MAPKAPK2 (human)
  • PKACA (human)
  • PKG1 iso2 (human)
  • PRKD1 (human)
Putative in vivo kinases:
  • Akt1 (human)
  • P70S6KB (human)
  • PRKD1 (human)
Regulatory protein:
  • AR (human)
  • Chk1 (human)
  • MAPKAPK2 (human)
  • PRKD1 (human)
Treatment
  • ACh
  • adriamycin
  • ADT
  • angiotensin-(1-7)
  • anisomycin
  • arsenite
  • bicalutamide
  • bombesin
  • bryostatin_1
  • cisplatin
  • D3T
  • EGF
  • FGF2
  • fluorouracil
  • Go_6976
  • H2O2
  • heat_shock
  • heregulin
  • IL-1b
  • ionizing_radiation
  • ischemia
  • lapatinib
  • menadione
  • metastatic potential
  • metribolone
  • MG132_withdrawal
  • microcystin-LR
  • MK2-I
  • mutation
  • neurotensin
  • nocodazole
  • OSU-03012
  • PD98059
  • PF3644022
  • phorbol_ester
  • SB202190
  • SB203347
  • SB203580
  • serum
  • siRNA
  • SP600125
  • taxol
  • thiolutin
  • thrombin
  • TNF
  • U0126
  • UCN-01
  • UV
HSP27 (human) RALsRQLssGVsEIr S82-p
HSP27 (mouse) RALNRQLssGVsEIR S86-p
HSP27 (rat) RALNRQLssGVsEIR S86-p
HSP27 (pig) RLLSRQLsSGVSEIQ S84-p
HSP27 (hamster) RALNRQLsSGVSEIR S90-p
HSP27 (chicken) GRALsELSsGISEIR S80
HSP27 (dog) RALSRQLsSGVSEIR S86-p
HSP27 (cow) RALSRQLsSGVSEIQ S78-p
S83-p
ALsRQLssGVsEIrH
Upstream
1 43
Treatment
  • ionizing_radiation
HSP27 (human) ALsRQLssGVsEIrH S83-p
HSP27 (mouse) ALNRQLssGVsEIRQ S87-p
HSP27 (rat) ALNRQLssGVsEIRQ S87-p
HSP27 (pig) LLSRQLsSGVSEIQQ S85
HSP27 (hamster) ALNRQLsSGVSEIRQ S91
HSP27 (chicken) RALsELSsGISEIRQ S81-p
HSP27 (dog) ALSRQLsSGVSEIRQ S87
HSP27 (cow) ALSRQLsSGVSEIQQ S79
S86-p
RQLssGVsEIrHtAD
2 14
HSP27 (human) RQLssGVsEIrHtAD S86-p
HSP27 (mouse) RQLssGVsEIRQTAD S90-p
HSP27 (rat) RQLssGVsEIRQTAD S90-p
HSP27 (pig) RQLsSGVSEIQQTAD S88
HSP27 (hamster) RQLsSGVSEIRQTAD S94
HSP27 (chicken) sELSsGISEIRQSAD S84
HSP27 (dog) RQLsSGVSEIRQTAD S90
HSP27 (cow) RQLsSGVSEIQQTAD S82
R89-m1
ssGVsEIrHtADRWR
0 2
HSP27 (human) ssGVsEIrHtADRWR R89-m1
HSP27 (mouse) ssGVsEIRQTADRWR R93
HSP27 (rat) ssGVsEIRQTADRWR R93
HSP27 (pig) sSGVSEIQQTADRWR Q91
HSP27 (hamster) sSGVSEIRQTADRWR R97
HSP27 (chicken) SsGISEIRQSADSWK R87
HSP27 (dog) sSGVSEIRQTADRWR R93
HSP27 (cow) sSGVSEIQQTADRWR Q85
T91-p
GVsEIrHtADRWRVs
0 1
HSP27 (human) GVsEIrHtADRWRVs T91-p
HSP27 (mouse) GVsEIRQTADRWRVS T95
HSP27 (rat) GVsEIRQTADRWRVs T95
HSP27 (pig) GVSEIQQTADRWRVS T93
HSP27 (hamster) GVSEIRQTADRWRVS T99
HSP27 (chicken) GISEIRQSADSWKVT S89
HSP27 (dog) GVSEIRQTADRWRVS T95
HSP27 (cow) GVSEIQQTADRWRVS T87
S98-p
tADRWRVsLDVNHFA
0 9
HSP27 (human) tADRWRVsLDVNHFA S98-p
HSP27 (mouse) TADRWRVSLDVNHFA S102
HSP27 (rat) TADRWRVsLDVNHFA S102-p
HSP27 (pig) TADRWRVSLDVNHFA S100
HSP27 (hamster) TADRWRVSLDVNHFA S106
HSP27 (chicken) SADSWKVTLDVNHFA T96
HSP27 (dog) TADRWRVSLDVNHFA S102
HSP27 (cow) TADRWRVSLDVNHFA S94
K112-ub
APDELTVktkDGVVE
0 36
HSP27 (human) APDELTVktkDGVVE K112-ub
HSP27 (mouse) APEELTVkTkEGVVE K116-ub
HSP27 (rat) APEELTVKtKEGVVE K116
HSP27 (pig) APEELTVKTKDGVVE K114
HSP27 (hamster) APEELTVKTKEGVVE K120
HSP27 (chicken) APEELVVKTKDNIVE K110
HSP27 (dog) APEELTVKTKDGVVE K116
HSP27 (cow) APEELTVKTKDGVVE K108
T113-p
PDELTVktkDGVVEI
1 2
HSP27 (human) PDELTVktkDGVVEI T113-p
HSP27 (mouse) PEELTVkTkEGVVEI T117
HSP27 (rat) PEELTVKtKEGVVEI T117-p
HSP27 (pig) PEELTVKTKDGVVEI T115
HSP27 (hamster) PEELTVKTKEGVVEI T121
HSP27 (chicken) PEELVVKTKDNIVEI T111
HSP27 (dog) PEELTVKTKDGVVEI T117
HSP27 (cow) PEELTVKTKDGVVEI T109
K114-ub
DELTVktkDGVVEIt
0 47
HSP27 (human) DELTVktkDGVVEIt K114-ub
HSP27 (mouse) EELTVkTkEGVVEIT K118-ub
HSP27 (rat) EELTVKtKEGVVEIT K118
HSP27 (pig) EELTVKTKDGVVEIT K116
HSP27 (hamster) EELTVKTKEGVVEIT K122
HSP27 (chicken) EELVVKTKDNIVEIT K112
HSP27 (dog) EELTVKTKDGVVEIT K118
HSP27 (cow) EELTVKTKDGVVEIT K110
K114-sm
DELTVktkDGVVEIt
0 1
HSP27 (human) DELTVktkDGVVEIt K114-sm
HSP27 (mouse) EELTVkTKEGVVEIT K118
HSP27 (rat) EELTVKtKEGVVEIT K118
HSP27 (pig) EELTVKTKDGVVEIT K116
HSP27 (hamster) EELTVKTKEGVVEIT K122
HSP27 (chicken) EELVVKTKDNIVEIT K112
HSP27 (dog) EELTVKTKDGVVEIT K118
HSP27 (cow) EELTVKTKDGVVEIT K110
T121-p
kDGVVEItGkHEERQ
0 3
HSP27 (human) kDGVVEItGkHEERQ T121-p
HSP27 (mouse) kEGVVEITGKHEERQ T125
HSP27 (rat) KEGVVEITGkHEERQ T125
HSP27 (pig) KDGVVEITGKHEERQ T123
HSP27 (hamster) KEGVVEITGKHEERQ T129
HSP27 (chicken) KDNIVEITGKHEEKQ T119
HSP27 (dog) KDGVVEITGKHEERQ T125
HSP27 (cow) KDGVVEITGKHEERQ T117
K123-ac
GVVEItGkHEERQDE
Upstream
0 11
Treatment
  • vorinostat
HSP27 (human) GVVEItGkHEERQDE K123-ac
HSP27 (mouse) GVVEITGKHEERQDE K127
HSP27 (rat) GVVEITGkHEERQDE K127-ac
HSP27 (pig) GVVEITGKHEERQDE K125
HSP27 (hamster) GVVEITGKHEERQDE K131
HSP27 (chicken) NIVEITGKHEEKQDE K121
HSP27 (dog) GVVEITGKHEERQDE K127
HSP27 (cow) GVVEITGKHEERQDE K119
K123-ub
GVVEItGkHEERQDE
0 16
HSP27 (human) GVVEItGkHEERQDE K123-ub
HSP27 (mouse) GVVEITGKHEERQDE K127
HSP27 (rat) GVVEITGKHEERQDE K127
HSP27 (pig) GVVEITGKHEERQDE K125
HSP27 (hamster) GVVEITGKHEERQDE K131
HSP27 (chicken) NIVEITGKHEEKQDE K121
HSP27 (dog) GVVEITGKHEERQDE K127
HSP27 (cow) GVVEITGKHEERQDE K119
Y133-p
ERQDEHGyIsRCFtR
0 27
HSP27 (human) ERQDEHGyIsRCFtR Y133-p
HSP27 (mouse) ERQDEHGYIsRCFTR Y137
HSP27 (rat) ERQDEHGYISRCFTR Y137
HSP27 (pig) ERQDEHGFISRCFTR F135
HSP27 (hamster) ERQDEHGYISRCFTR Y141
HSP27 (chicken) EKQDEHGFISRCFTR F131
HSP27 (dog) ERQDEHGYISRRLTP Y137
HSP27 (cow) ERQDEHGYISRCFTR Y129
S135-p
QDEHGyIsRCFtRky
Upstream
0 6
Treatment
  • EGF
  • U0126
HSP27 (human) QDEHGyIsRCFtRky S135-p
HSP27 (mouse) QDEHGYIsRCFTRkY S139-p
HSP27 (rat) QDEHGYISRCFTRKY S139
HSP27 (pig) QDEHGFISRCFTRKY S137
HSP27 (hamster) QDEHGYISRCFTRKY S143
HSP27 (chicken) QDEHGFISRCFTRKY S133
HSP27 (dog) QDEHGYISRRLTPKY S139
HSP27 (cow) QDEHGYISRCFTRKY S131
T139-p
GyIsRCFtRkytLPP
0 5
HSP27 (human) GyIsRCFtRkytLPP T139-p
HSP27 (mouse) GYIsRCFTRkYtLPP T143
HSP27 (rat) GYISRCFTRKYtLPP T143
HSP27 (pig) GFISRCFTRKYTLPP T141
HSP27 (hamster) GYISRCFTRKYTLPP T147
HSP27 (chicken) GFISRCFTRKYTLPP T137
HSP27 (dog) GYISRRLTPKYTLPP T143
HSP27 (cow) GYISRCFTRKYTLPP T135
K141-ub
IsRCFtRkytLPPGV
0 2
HSP27 (human) IsRCFtRkytLPPGV K141-ub
HSP27 (mouse) IsRCFTRkYtLPPGV K145-ub
HSP27 (rat) ISRCFTRKYtLPPGV K145
HSP27 (pig) ISRCFTRKYTLPPGV K143
HSP27 (hamster) ISRCFTRKYTLPPGV K149
HSP27 (chicken) ISRCFTRKYTLPPGV K139
HSP27 (dog) ISRRLTPKYTLPPGV K145
HSP27 (cow) ISRCFTRKYTLPPGV K137
K141-ac
IsRCFtRkytLPPGV
0 2
HSP27 (human) IsRCFtRkytLPPGV K141-ac
HSP27 (mouse) IsRCFTRKYtLPPGV K145
HSP27 (rat) ISRCFTRKYtLPPGV K145
HSP27 (pig) ISRCFTRKYTLPPGV K143
HSP27 (hamster) ISRCFTRKYTLPPGV K149
HSP27 (chicken) ISRCFTRKYTLPPGV K139
HSP27 (dog) ISRRLTPKYTLPPGV K145
HSP27 (cow) ISRCFTRKYTLPPGV K137
Y142-p
sRCFtRkytLPPGVD
0 3
HSP27 (human) sRCFtRkytLPPGVD Y142-p
HSP27 (mouse) sRCFTRkYtLPPGVD Y146
HSP27 (rat) SRCFTRKYtLPPGVD Y146
HSP27 (pig) SRCFTRKYTLPPGVD Y144
HSP27 (hamster) SRCFTRKYTLPPGVD Y150
HSP27 (chicken) SRCFTRKYTLPPGVE Y140
HSP27 (dog) SRRLTPKYTLPPGVD Y146
HSP27 (cow) SRCFTRKYTLPPGVD Y138
T143-p
RCFtRkytLPPGVDP
Upstream
1 15
Kinase, in vitro:
  • PKACA (human)
  • PKG1 iso2 (human)
HSP27 (human) RCFtRkytLPPGVDP T143-p
HSP27 (mouse) RCFTRkYtLPPGVDP T147-p
HSP27 (rat) RCFTRKYtLPPGVDP T147-p
HSP27 (pig) RCFTRKYTLPPGVDP T145
HSP27 (hamster) RCFTRKYTLPPGVDP T151
HSP27 (chicken) RCFTRKYTLPPGVEA T141
HSP27 (dog) RRLTPKYTLPPGVDP T147
HSP27 (cow) RCFTRKYTLPPGVDP T139
T162-p
SSLSPEGtLtVEAPM
0 1
HSP27 (human) SSLSPEGtLtVEAPM T162-p
HSP27 (mouse) SSLSPEGTLTVEAPL T166
HSP27 (rat) SSLSPEGTLTVEAPL T166
HSP27 (pig) SSLSPEGTLSVEAPL T164
HSP27 (hamster) SSLSPEGTLTVEAPL T170
HSP27 (chicken) SSLSPDGMLTVEAPL M160
HSP27 (dog) SSLSPEGTLTVEAPM T166
HSP27 (cow) SSLSPEGTLTVEAPL T158
T164-p
LSPEGtLtVEAPMPk
0 1
HSP27 (human) LSPEGtLtVEAPMPk T164-p
HSP27 (mouse) LSPEGTLTVEAPLPK T168
HSP27 (rat) LSPEGTLTVEAPLPK T168
HSP27 (pig) LSPEGTLSVEAPLPK S166
HSP27 (hamster) LSPEGTLTVEAPLPK T172
HSP27 (chicken) LSPDGMLTVEAPLPK T162
HSP27 (dog) LSPEGTLTVEAPMPK T168
HSP27 (cow) LSPEGTLTVEAPLPK T160
K171-ub
tVEAPMPkLAtQsNE
0 1
HSP27 (human) tVEAPMPkLAtQsNE K171-ub
HSP27 (mouse) TVEAPLPKAVTQsAE K175
HSP27 (rat) TVEAPLPKAVTQSAE K175
HSP27 (pig) SVEAPLPKPATQSAE K173
HSP27 (hamster) TVEAPLPKTATQSAE K179
HSP27 (chicken) TVEAPLPKPAIQSSE K169
HSP27 (dog) TVEAPMPKPATQSAE K175
HSP27 (cow) TVEAPLPKSATQSAE K167
T174-p
APMPkLAtQsNEItI
0 9
HSP27 (human) APMPkLAtQsNEItI T174-p
HSP27 (mouse) APLPKAVTQsAEITI T178
HSP27 (rat) APLPKAVTQSAEITI T178
HSP27 (pig) APLPKPATQSAEITI T176
HSP27 (hamster) APLPKTATQSAEITI T182
HSP27 (chicken) APLPKPAIQSSEITI I172
HSP27 (dog) APMPKPATQSAEITI T178
HSP27 (cow) APLPKSATQSAEITI T170
S176-p
MPkLAtQsNEItIPV
Upstream
1 8
Kinase, in vitro:
  • P38A (human)
Treatment
  • ischemia
HSP27 (human) MPkLAtQsNEItIPV S176-p
HSP27 (mouse) LPKAVTQsAEITIPV S180-p
HSP27 (rat) LPKAVTQSAEITIPV S180
HSP27 (pig) LPKPATQSAEITIPV S178
HSP27 (hamster) LPKTATQSAEITIPV S184
HSP27 (chicken) LPKPAIQSSEITIPV S174
HSP27 (dog) MPKPATQSAEITIPV S180
HSP27 (cow) LPKSATQSAEITIPV S172
T180-p
AtQsNEItIPVtFEs
0 1
HSP27 (human) AtQsNEItIPVtFEs T180-p
HSP27 (mouse) VTQsAEITIPVTFEA T184
HSP27 (rat) VTQSAEITIPVTFEA T184
HSP27 (pig) ATQSAEITIPVTFEA T182
HSP27 (hamster) ATQSAEITIPVTFEA T188
HSP27 (chicken) AIQSSEITIPVTVEA T178
HSP27 (dog) ATQSAEITIPVTFEA T184
HSP27 (cow) ATQSAEITIPVTFQA T176
T184-p
NEItIPVtFEsRAQL
0 3
HSP27 (human) NEItIPVtFEsRAQL T184-p
HSP27 (mouse) AEITIPVTFEARAQI T188
HSP27 (rat) AEITIPVTFEARAQI T188
HSP27 (pig) AEITIPVTFEARAQL T186
HSP27 (hamster) AEITIPVTFEARAQI T192
HSP27 (chicken) SEITIPVTVEAKKEE T182
HSP27 (dog) AEITIPVTFEARAQI T188
HSP27 (cow) AEITIPVTFQARAQL T180
S187-p
tIPVtFEsRAQLGGP
0 3
HSP27 (human) tIPVtFEsRAQLGGP S187-p
HSP27 (mouse) TIPVTFEARAQIGGP A191
HSP27 (rat) TIPVTFEARAQIGGP A191
HSP27 (pig) TIPVTFEARAQLGGT A189
HSP27 (hamster) TIPVTFEARAQIGGQ A195
HSP27 (chicken) TIPVTVEAKKEEPAK A185
HSP27 (dog) TIPVTFEARAQIGGP A191
HSP27 (cow) TIPVTFQARAQLGGP A183
K198-ub
LGGPEAAksDEtAAk
0 53
HSP27 (human) LGGPEAAksDEtAAk K198-ub
HSP27 (mouse) IGGPEAGksEQsGAK K202-ub
HSP27 (rat) IGGPESEQSGAK___ Q202
HSP27 (pig) LGGTEAGKSEKPGTK K200
HSP27 (hamster) IGGQEAGKSEQSGAK K206
HSP27 (chicken) IPVTVEAKKEEPAKK K186
HSP27 (dog) IGGPEAGKSEQSGAK K202
HSP27 (cow) LGGPEAGKSEQPENK K194
K198-sm
LGGPEAAksDEtAAk
0 2
HSP27 (human) LGGPEAAksDEtAAk K198-sm
HSP27 (mouse) IGGPEAGKsEQsGAK K202
HSP27 (rat) IGGPESEQSGAK___ Q202
HSP27 (pig) LGGTEAGKSEKPGTK K200
HSP27 (hamster) IGGQEAGKSEQSGAK K206
HSP27 (chicken) IPVTVEAKKEEPAKK K186
HSP27 (dog) IGGPEAGKSEQSGAK K202
HSP27 (cow) LGGPEAGKSEQPENK K194
S199-p
GGPEAAksDEtAAk_
Upstream
0 23
Treatment
  • EGF
  • ZK-Thiazolidinone
HSP27 (human) GGPEAAksDEtAAk_ S199-p
HSP27 (mouse) GGPEAGksEQsGAK_ S203-p
HSP27 (rat) GGPESEQSGAK____ S203
HSP27 (pig) GGTEAGKSEKPGTK_ S201
HSP27 (hamster) GGQEAGKSEQSGAK_ S207
HSP27 (chicken) PVTVEAKKEEPAKK_ K187
HSP27 (dog) GGPEAGKSEQSGAK_ S203
HSP27 (cow) GGPEAGKSEQPENK_ S195
T202-p
EAAksDEtAAk____
0 3
HSP27 (human) EAAksDEtAAk____ T202-p
HSP27 (mouse) EAGksEQsGAK____ S206-p
HSP27 (rat) gap -
HSP27 (pig) EAGKSEKPGTK____ P204
HSP27 (hamster) EAGKSEQSGAK____ S210
HSP27 (chicken) gap -
HSP27 (dog) EAGKSEQSGAK____ S206
HSP27 (cow) EAGKSEQPENK____ P198
K205-ac
ksDEtAAk_______
0 53
HSP27 (human) ksDEtAAk_______ K205-ac
HSP27 (mouse) ksEQsGAK_______ K209
HSP27 (rat) ESEQSGAK_______ K206
HSP27 (pig) KSEKPGTK_______ K207
HSP27 (hamster) KSEQSGAK_______ K213
HSP27 (chicken) KKEEPAKK_______ K193
HSP27 (dog) KSEQSGAK_______ K209
HSP27 (cow) KSEQPENK_______ K201
K205-ub
ksDEtAAk_______
0 4
HSP27 (human) ksDEtAAk_______ K205-ub
HSP27 (mouse) ksEQsGAK_______ K209
HSP27 (rat) ESEQSGAK_______ K206
HSP27 (pig) KSEKPGTK_______ K207
HSP27 (hamster) KSEQSGAK_______ K213
HSP27 (chicken) KKEEPAKK_______ K193
HSP27 (dog) KSEQSGAK_______ K209
HSP27 (cow) KSEQPENK_______ K201