Other Species / Isoforms
  HDAC5 (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

 HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
S3-p
_____MNsPNEsDGM
0 1
HDAC5 (human) _____MNsPNEsDGM S3-p
HDAC5 iso2 (human) gap -
HDAC5 iso3 (human) gap -
HDAC5 (mouse) gap -
HDAC5 (rat) gap -
S7-p
_MNsPNEsDGMSGRE
0 1
HDAC5 (human) _MNsPNEsDGMSGRE S7-p
HDAC5 iso2 (human) gap -
HDAC5 iso3 (human) gap -
HDAC5 (mouse) gap -
HDAC5 (rat) gap -
K35-sm
IPVTVEVkPVLPRAM
0 1
HDAC5 (human) IPVTVEVkPVLPRAM K35-sm
HDAC5 iso2 (human) IPVTVEVKPVLPRAM K35
HDAC5 iso3 (human) IPVTVEVKPVLPRAM K36
HDAC5 (mouse) IPVAVEVKPVLPGAM K35
HDAC5 (rat) gap -
S53-p
MGGGGGGsPsPVELR
0 6
HDAC5 (human) MGGGGGGsPsPVELR S53-p
HDAC5 iso2 (human) MGGGGGGSPSPVELR S53
HDAC5 iso3 (human) MGGGGGGSPSPVELR S54
HDAC5 (mouse) MGGGGGGsPSPVELR S53-p
HDAC5 (rat) gap -
S55-p
GGGGGsPsPVELRGA
0 2
HDAC5 (human) GGGGGsPsPVELRGA S55-p
HDAC5 iso2 (human) GGGGGSPSPVELRGA S55
HDAC5 iso3 (human) GGGGGSPSPVELRGA S56
HDAC5 (mouse) GGGGGsPSPVELRGA S55
HDAC5 (rat) gap -
S66-p
LRGALVGsVDPtLRE
0 1
HDAC5 (human) LRGALVGsVDPtLRE S66-p
HDAC5 iso2 (human) LRGALVGSVDPTLRE S66
HDAC5 iso3 (human) LRGALVGSVDPTLRE S67
HDAC5 (mouse) LRGALAGPMDPALRE P66
HDAC5 (rat) gap -
T70-p
LVGsVDPtLREQQLQ
0 1
HDAC5 (human) LVGsVDPtLREQQLQ T70-p
HDAC5 iso2 (human) LVGSVDPTLREQQLQ T70
HDAC5 iso3 (human) LVGSVDPTLREQQLQ T71
HDAC5 (mouse) LAGPMDPALREQQLQ A70
HDAC5 (rat) gap -
K84-ub
QQELLALkQQQQLQK
0 1
HDAC5 (human) QQELLALkQQQQLQK K84-ub
HDAC5 iso2 (human) QQELLALKQQQQLQK K84
HDAC5 iso3 (human) QQELLALKQQQQLQK K85
HDAC5 (mouse) QQELLVLKQQQQLQK K84
HDAC5 (rat) under review -
K115-ub
QHEVQLQkHLKQQQE
0 1
HDAC5 (human) QHEVQLQkHLKQQQE K115-ub
HDAC5 iso2 (human) QHEVQLQKHLKQQQE K115
HDAC5 iso3 (human) QHEVQLQKHLKQQQE K116
HDAC5 (mouse) QHEVQLQKHLKQQQE K115
HDAC5 (rat) under review -
K136-ub
QQEMLAAkRQQELEQ
0 1
HDAC5 (human) QQEMLAAkRQQELEQ K136-ub
HDAC5 iso2 (human) QQEMLAAKRQQELEQ K136
HDAC5 iso3 (human) QQEMLAAKRQQELEQ K137
HDAC5 (mouse) QQEMLAAKRQQELEQ K127
HDAC5 (rat) under review -
S180-p
SKESAIAstEVKLRL
0 1
HDAC5 (human) SKESAIAstEVKLRL S180-p
HDAC5 iso2 (human) SKESAIASTEVKLRL S180
HDAC5 iso3 (human) SKESAIASTEVKLRL S181
HDAC5 (mouse) SKESAIASTEVKLRL S171
HDAC5 (rat) ____AIASTEVKLRL S4
T181-p
KESAIAstEVKLRLQ
0 1
HDAC5 (human) KESAIAstEVKLRLQ T181-p
HDAC5 iso2 (human) KESAIASTEVKLRLQ T181
HDAC5 iso3 (human) KESAIASTEVKLRLQ T182
HDAC5 (mouse) KESAIASTEVKLRLQ T172
HDAC5 (rat) ___AIASTEVKLRLQ T5
S206-p
TPGGLNHsLPQHPKC
0 1
HDAC5 (human) TPGGLNHsLPQHPKC S206-p
HDAC5 iso2 (human) TPGGLNHSLPQHPKC S206
HDAC5 iso3 (human) TPGGLNHSLPQHPKC S207
HDAC5 (mouse) TPGGLNHSLPQHPKC S197
HDAC5 (rat) TPGGLNHSLPQHPKC S30
S220-p
CWGAHHAsLDQSSPP
0 1
HDAC5 (human) CWGAHHAsLDQSSPP S220-p
HDAC5 iso2 (human) CWGAHHASLDQSSPP S220
HDAC5 iso3 (human) CWGAHHASLDQSSPP S221
HDAC5 (mouse) CWGAHHASLDQSSPP S211
HDAC5 (rat) CWGAHHASLDQSSPP S44
T234-p
PQSGPPGtPPSYKLP
0 1
HDAC5 (human) PQSGPPGtPPSYKLP T234-p
HDAC5 iso2 (human) PQSGPPGTPPSYKLP T234
HDAC5 iso3 (human) PQSGPPGTPPSYKLP T235
HDAC5 (mouse) PQSGPPGTPPSYKLP T225
HDAC5 (rat) PQSGPPGTPPSYKLP T58
S259-p
FPLRKTAsEPNLKVR
Upstream
Downstream
24 46
HDAC5 (human)
S259-p
HDAC5 (mouse)
S250-p
Effects on Modified Protein
  • activity, induced
  • enzymatic activity, inhibited
  • intracellular localization
  • molecular association, regulation
Effects on Biological Processes:
  • apoptosis, induced
  • cell cycle regulation
  • cell differentiation, altered
  • cell motility, altered
  • chromatin organization, altered
  • transcription, altered
  • transcription, induced
Kinase, in vitro:
  • AMPKA1 (human)
  • CAMK4 (human)
  • PKCD (human)
Putative in vivo kinases:
  • AMPKA1 (human)
  • AMPKA2 (human)
  • CAMK1A (human)
  • CAMK2A (human)
  • CAMK4 (human)
  • MARK2 (human)
  • PRKD1 (human)
  • QIK (human)
  • TAK1 (human)
Putative upstream phosphatases:
  • PPP2R2A (human)
Treatment
  • acadesine
  • BDNF
  • bpkdi
  • cAMP_analog
  • CGP_20712A
  • colforsin
  • etoposide
  • GF109203X
  • Go_6976
  • isoproterenol
  • KN-92
  • KN-93
  • LY294002
  • N6-benzoyl-cAMP
  • okadaic_acid
  • phorbol_ester
  • Ro31-8425
  • staurosporine
  • tiron
  • U73122
  • VEGF
HDAC5 (human) FPLRKTAsEPNLKVR S259-p
HDAC5 iso2 (human) FPLRKTASEPNLKVR S259
HDAC5 iso3 (human) FPLRKTASEPNLKVR S260
HDAC5 (mouse) FPLRKTAsEPNLKVR S250-p
HDAC5 (rat) FPLRKTAsEPNLKVR S83-p
S278-p
QKVAERRssPLLRRK
Upstream
Downstream
2 14
Effects on Modified Protein
  • enzymatic activity, induced
  • molecular association, regulation
Kinase, in vitro:
  • AurB (human)
Putative in vivo kinases:
  • AurB (human)
Treatment
  • angiotensin_2
  • hesperadin
  • nocodazole
  • siRNA
HDAC5 (human) QKVAERRssPLLRRK S278-p
HDAC5 iso2 (human) QKVAERRSSPLLRRK S278
HDAC5 iso3 (human) QKVAERRSSPLLRRK S279
HDAC5 (mouse) QKVAERRssPLLRRK S269-p
HDAC5 (rat) QKVAERRSsPLLRRK S102
S279-p
KVAERRssPLLRRKD
Upstream
Downstream
6 20
Effects on Modified Protein
  • enzymatic activity, induced
  • intracellular localization
  • molecular association, regulation
  • protein conformation
Effects on Biological Processes:
  • neural plasticity
  • transcription, inhibited
Kinase, in vitro:
  • CDK5 (human)
  • PKACA (human)
Phosphatases, in vitro:
  • PPP2CA (human)
Putative in vivo kinases:
  • CDK5 (human)
  • PKACA (human)
Treatment
  • CGP_20712A
  • cocaine
  • colforsin
  • CP-681301
  • H-89
  • IBMX
  • isoproterenol
  • N6-benzoyl-cAMP
  • NKH_477
  • nocodazole
  • okadaic_acid
  • quinpirole
  • SB203580
  • seliciclib
  • SKF81297
  • tautomycetin
HDAC5 (human) KVAERRssPLLRRKD S279-p
HDAC5 iso2 (human) KVAERRSSPLLRRKD S279
HDAC5 iso3 (human) KVAERRSSPLLRRKD S280
HDAC5 (mouse) KVAERRssPLLRRKD S270-p
HDAC5 (rat) KVAERRSsPLLRRKD S103-p
T288-p
LLRRKDGtVIstFKK
0 1
HDAC5 (human) LLRRKDGtVIstFKK T288-p
HDAC5 iso2 (human) LLRRKDGTVISTFKK T288
HDAC5 iso3 (human) LLRRKDGTVISTFKK T289
HDAC5 (mouse) LLRRKDGTVISTFKK T279
HDAC5 (rat) LLRRKDGTVISTFKK T112
S291-p
RKDGtVIstFKKRAV
0 1
HDAC5 (human) RKDGtVIstFKKRAV S291-p
HDAC5 iso2 (human) RKDGTVISTFKKRAV S291
HDAC5 iso3 (human) RKDGTVISTFKKRAV S292
HDAC5 (mouse) RKDGTVISTFKKRAV S282
HDAC5 (rat) RKDGTVISTFKKRAV S115
T292-p
KDGtVIstFKKRAVE
Upstream
1 1
Kinase, in vitro:
  • PKN1 (human)
HDAC5 (human) KDGtVIstFKKRAVE T292-p
HDAC5 iso2 (human) KDGTVISTFKKRAVE T292
HDAC5 iso3 (human) KDGTVISTFKKRAVE T293
HDAC5 (mouse) KDGTVISTFKKRAVE T283
HDAC5 (rat) KDGTVISTFKKRAVE T116
S368-p
FSLYTSPsLPNISLG
0 1
HDAC5 (human) FSLYTSPsLPNISLG S368-p
HDAC5 iso2 (human) FSLYTSPSLPNISLG S368
HDAC5 iso3 (human) FSLYTSPSLPNISLG S369
HDAC5 (mouse) FSLYTSPSLPNISLG S359
HDAC5 (rat) FSLYTSPSLPNISLG S192
S469-p
AVPLHGQsPLVTGER
0 1
HDAC5 (human) AVPLHGQsPLVTGER S469-p
HDAC5 iso2 (human) AVPLHGQSPLVTGER S469
HDAC5 iso3 (human) AVPLHGQSPLVTGER S470
HDAC5 (mouse) AVPLHGQSPLVTGER S459
HDAC5 (rat) AVPLHGQSPLVTGER S293
T496-p
RHRPLSRtQsSPLPQ
0 2
HDAC5 (human) RHRPLSRtQsSPLPQ T496-p
HDAC5 iso2 (human) RHRPLSRTQSSPLPQ T496
HDAC5 iso3 (human) RHRPLSRTQSSPLPQ T497
HDAC5 (mouse) RHRPLSRtQsSPLPQ T486-p
HDAC5 (rat) RHRPLSRTQsSPLPQ T320
S498-p
RPLSRtQsSPLPQsP
Upstream
Downstream
24 9
HDAC5 (human)
S498-p
HDAC5 (mouse)
S488-p
Effects on Modified Protein
  • activity, induced
  • enzymatic activity, inhibited
  • intracellular localization
  • molecular association, regulation
Effects on Biological Processes:
  • apoptosis, induced
  • cell cycle regulation
  • cell differentiation, altered
  • cell motility, altered
  • chromatin organization, altered
  • transcription, altered
  • transcription, induced
Kinase, in vitro:
  • AMPKA1 (human)
  • CAMK4 (human)
  • PRKD1 (human)
  • PRKD2 (human)
  • PRKD3 (human)
Putative in vivo kinases:
  • AMPKA1 (human)
  • AMPKA2 (human)
  • CAMK1A (human)
  • CAMK2A (human)
  • CAMK4 (human)
  • PRKD1 (human)
Treatment
  • 6-Bnz cAMP
  • 8-Rp-cAMP
  • acadesine
  • bpkdi
  • cAMP_analog
  • CGP_20712A
  • colforsin
  • endothelin
  • etoposide
  • GF109203X
  • Go_6976
  • Go_6983
  • IBMX
  • isoproterenol
  • KN-92
  • KN-93
  • LY294002
  • N6-benzoyl-cAMP
  • NKH_477
  • okadaic_acid
  • phenylephrine
  • phorbol_ester
  • Ro31-8220
  • Ro31-8425
  • tiron
  • U73122
  • VEGF
HDAC5 (human) RPLSRtQsSPLPQsP S498-p
HDAC5 iso2 (human) RPLSRTQSSPLPQSP S498
HDAC5 iso3 (human) RPLSRTQSSPLPQSP S499
HDAC5 (mouse) RPLSRtQsSPLPQSP S488-p
HDAC5 (rat) RPLSRTQsSPLPQSP S322-p
S504-p
QsSPLPQsPQALQQL
0 1
HDAC5 (human) QsSPLPQsPQALQQL S504-p
HDAC5 iso2 (human) QSSPLPQSPQALQQL S504
HDAC5 iso3 (human) QSSPLPQSPQALQQL S505
HDAC5 (mouse) QsSPLPQSPQALQQL S494
HDAC5 (rat) QsSPLPQSPQALQQL S328
K533-ac
QQQLQLGkILTkTGE
Upstream
0 2
Treatment
  • MS275
HDAC5 (human) QQQLQLGkILTkTGE K533-ac
HDAC5 iso2 (human) QQQLQLGKILTKTGE K533
HDAC5 iso3 (human) QQQLQLGKILTKTGE K534
HDAC5 (mouse) QQQMQLGKILTKTGE K523
HDAC5 (rat) QQQMQLGKILTKTGE K357
K533-sm
QQQLQLGkILTkTGE
0 1
HDAC5 (human) QQQLQLGkILTkTGE K533-sm
HDAC5 iso2 (human) QQQLQLGKILTKTGE K533
HDAC5 iso3 (human) QQQLQLGKILTKTGE K534
HDAC5 (mouse) QQQMQLGKILTKTGE K523
HDAC5 (rat) QQQMQLGKILTKTGE K357
K537-ub
QLGkILTkTGELPRQ
0 1
HDAC5 (human) QLGkILTkTGELPRQ K537-ub
HDAC5 iso2 (human) QLGKILTKTGELPRQ K537
HDAC5 iso3 (human) QLGKILTKTGELPRQ K538
HDAC5 (mouse) QLGKILTKTGELSRQ K527
HDAC5 (rat) QLGKILTKTGELSRQ K361
T546-p
GELPRQPttHPEETE
0 9
HDAC5 (human) GELPRQPttHPEETE T546-p
HDAC5 iso2 (human) GELPRQPTTHPEETE T546
HDAC5 iso3 (human) GELPRQPTTHPEETE T547
HDAC5 (mouse) GELSRQPtTHPEETE T536-p
HDAC5 (rat) GELSRQPTTHPEETE T370
T547-p
ELPRQPttHPEETEE
0 4
HDAC5 (human) ELPRQPttHPEETEE T547-p
HDAC5 iso2 (human) ELPRQPTTHPEETEE T547
HDAC5 iso3 (human) ELPRQPTTHPEETEE T548
HDAC5 (mouse) ELSRQPtTHPEETEE T537
HDAC5 (rat) ELSRQPTTHPEETEE T371
K605-sm
EEDCIQVkDEEGEsG
0 1
HDAC5 (human) EEDCIQVkDEEGEsG K605-sm
HDAC5 iso2 (human) EEDCIQVKDEEGESG K605
HDAC5 iso3 (human) EEDCIQVKDEEGESG K606
HDAC5 (mouse) EEDCIQVKDEDGEsG K594
HDAC5 (rat) EEDCIQVKDEDGEsG K427
S611-p
VkDEEGEsGAEEGPD
Downstream
2 19
Effects on Modified Protein
  • molecular association, regulation
HDAC5 (human) VkDEEGEsGAEEGPD S611-p
HDAC5 iso2 (human) VKDEEGESGAEEGPD S611
HDAC5 iso3 (human) VKDEEGESGAEEGPD S612
HDAC5 (mouse) VKDEDGEsGPDEGPD S600-p
HDAC5 (rat) VKDEDGEsGPDEGAD S433-p
Y642-p
PLQPLQVyQAPLSLA
Upstream
Downstream
1 1
Effects on Modified Protein
  • intracellular localization
Kinase, in vitro:
  • FAK (human)
Putative in vivo kinases:
  • FAK (human)
Treatment
  • fluid_shear_stress
  • PF562271
HDAC5 (human) PLQPLQVyQAPLSLA Y642-p
HDAC5 iso2 (human) PLQPLQVYQAPLSLA Y642
HDAC5 iso3 (human) PLQPLQVYQAPLSLA Y643
HDAC5 (mouse) QLQPLQVYQAPLSLA Y631
HDAC5 (rat) QLQPLQVYQAPLSLA Y464
S661-p
QALGRTQsSPAAPGG
Upstream
Downstream
1 39
Effects on Modified Protein
  • intracellular localization
Treatment
  • ischemia
HDAC5 (human) QALGRTQsSPAAPGG S661-p
HDAC5 iso2 (human) QALGRTQSSPAAPGG S661
HDAC5 iso3 (human) QALGRTQSSPAAPGG S662
HDAC5 (mouse) QALGRTQsSPAAPGs S650-p
HDAC5 (rat) QALGRTQSSPAAPGS S483
G668
sSPAAPGGMKsPPDQ
0 1
HDAC5 (human) sSPAAPGGMKsPPDQ G668
HDAC5 iso2 (human) SSPAAPGGMKSPPDQ G668
HDAC5 iso3 (human) SSPAAPGGMKSPPDQ G669
HDAC5 (mouse) sSPAAPGsMKsPtDQ S657-p
HDAC5 (rat) SSPAAPGSMKSPTDH S490
S671-p
AAPGGMKsPPDQPVK
0 5
HDAC5 (human) AAPGGMKsPPDQPVK S671-p
HDAC5 iso2 (human) AAPGGMKSPPDQPVK S671
HDAC5 iso3 (human) AAPGGMKSPPDQPVK S672
HDAC5 (mouse) AAPGsMKsPtDQPTV S660-p
HDAC5 (rat) AAPGSMKSPTDHPTV S493
P673
PGGMKsPPDQPVKHL
0 1
HDAC5 (human) PGGMKsPPDQPVKHL P673
HDAC5 iso2 (human) PGGMKSPPDQPVKHL P673
HDAC5 iso3 (human) PGGMKSPPDQPVKHL P674
HDAC5 (mouse) PGsMKsPtDQPTVVK T662-p
HDAC5 (rat) PGSMKSPTDHPTVER T495
S755-p
HTLLYGTsPLNRQKL
2 2
HDAC5 (human) HTLLYGTsPLNRQKL S755-p
HDAC5 iso2 (human) gap -
HDAC5 iso3 (human) HTLLYGTSPLNRQKL S756
HDAC5 (mouse) HTLLYGTSPLNRQKL S746
HDAC5 (rat) HTLLYGTSPLNRQKL S579
Y776-p
GPISQKMyAVLPCGG
0 1
HDAC5 (human) GPISQKMyAVLPCGG Y776-p
HDAC5 iso2 (human) GPISQKMYAVLPCGG Y691
HDAC5 iso3 (human) GPISQKMYAVLPCGG Y777
HDAC5 (mouse) GPISQKMYAMLPCGG Y767
HDAC5 (rat) GPISQKMYAMLPCGG Y600
S798-p
VWNEMHSssAVRMAV
0 1
HDAC5 (human) VWNEMHSssAVRMAV S798-p
HDAC5 iso2 (human) VWNEMHSSSAVRMAV S713
HDAC5 iso3 (human) VWNEMHSSSAVRMAV S799
HDAC5 (mouse) VWNEMHSSSAVRMAV S789
HDAC5 (rat) VWNEMHSSSAVRMAV S622
S799-p
WNEMHSssAVRMAVG
0 1
HDAC5 (human) WNEMHSssAVRMAVG S799-p
HDAC5 iso2 (human) WNEMHSSSAVRMAVG S714
HDAC5 iso3 (human) WNEMHSSSAVRMAVG S800
HDAC5 (mouse) WNEMHSSSAVRMAVG S790
HDAC5 (rat) WNEMHSSSAVRMAVG S623
N1040
AVLQQKPNINAVATL
0 1
HDAC5 (human) AVLQQKPNINAVATL N1040
HDAC5 iso2 (human) AVLQQKPNINAVATL N955
HDAC5 iso3 (human) AVLQQKPNINAVATL N1041
HDAC5 (mouse) AVLQQKPsVNAVATL S1031-p
HDAC5 (rat) AVLQQKPSINAVATL S864
S1059
EIQSKHWSCVQKFAA
0 1
HDAC5 (human) EIQSKHWSCVQKFAA S1059
HDAC5 iso2 (human) EIQSKHWSCVQKFAA S974
HDAC5 iso3 (human) EIQSKHWSCVQKFAA S1060
HDAC5 (mouse) EIQSKHWsCVQRFAA S1050-p
HDAC5 (rat) EIQSKHWSCVQRFAT S883
S1071-p
FAAGLGRsLREAQAG
0 2
HDAC5 (human) FAAGLGRsLREAQAG S1071-p
HDAC5 iso2 (human) FAAGLGRSLREAQAG S986
HDAC5 iso3 (human) FAAGLGRSLREAQAG S1072
HDAC5 (mouse) FAAGLGCsLREAQTG S1062-p
HDAC5 (rat) FATGLGCSLREAQTG S895
S1108-p
AAAAREHsPRPAEEP
Downstream
2 25
Effects on Modified Protein
  • molecular association, regulation
HDAC5 (human) AAAAREHsPRPAEEP S1108-p
HDAC5 iso2 (human) AAAAREHSPRPAEEP S1023
HDAC5 iso3 (human) AAAAREHSPRPAEEP S1109
HDAC5 (mouse) AVATQEHSPRPAEEP S1099
HDAC5 (rat) AAATQEHSPRPAEEP S932