Other Species / Isoforms
  SQSTM1 (mouse)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

 HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
K7
_MASFTVKAYLLGkE
1 0
SQSTM1 (human) _MASLTVkAyLLGkE K7-ub
SQSTM1 iso2 (human) gap -
SQSTM1 (mouse) _MASFTVKAYLLGkE K7
SQSTM1 (rat) _MASLTVKAYLLGKE K7
Y9
ASFTVKAYLLGkEEA
0 2
SQSTM1 (human) ASLTVkAyLLGkEDA Y9-p
SQSTM1 iso2 (human) gap -
SQSTM1 (mouse) ASFTVKAYLLGkEEA Y9
SQSTM1 (rat) ASLTVKAYLLGKEEA Y9
K13
VKAYLLGKEEATREI
0 1
SQSTM1 (human) VkAyLLGkEDAAREI K13-ac
SQSTM1 iso2 (human) gap -
SQSTM1 (mouse) VKAYLLGKEEATREI K13
SQSTM1 (rat) VKAYLLGKEEAAREI K13
K13-ub
VKAYLLGkEEATREI
1 54
SQSTM1 (human) VkAyLLGkEDAAREI K13-ub
SQSTM1 iso2 (human) gap -
SQSTM1 (mouse) VKAYLLGkEEATREI K13-ub
SQSTM1 (rat) VKAYLLGKEEAAREI K13
S24-p
TREIRRFsFCFsPEP
Upstream
0 87
Regulatory protein:
  • KRas (mouse)
SQSTM1 (human) AREIRRFsFCCsPEP S24-p
SQSTM1 iso2 (human) gap -
SQSTM1 (mouse) TREIRRFsFCFsPEP S24-p
SQSTM1 (rat) AREIRRFsFCFSPEP S24-p
S28-p
RRFsFCFsPEPEAEA
0 16
SQSTM1 (human) RRFsFCCsPEPEAEA S28-p
SQSTM1 iso2 (human) gap -
SQSTM1 (mouse) RRFsFCFsPEPEAEA S28-p
SQSTM1 (rat) RRFsFCFSPEPEAEA S28
S49
GPCERLLSRVAVLFP
0 2
SQSTM1 (human) GPCERLLsRVAALFP S49-p
SQSTM1 iso2 (human) gap -
SQSTM1 (mouse) GPCERLLSRVAVLFP S49
SQSTM1 (rat) GPCERLLSRVAVLFP S47
Y67
PGGFQAHYRDEDGDL
0 2
SQSTM1 (human) PGGFQAHyRDEDGDL Y67-p
SQSTM1 iso2 (human) gap -
SQSTM1 (mouse) PGGFQAHYRDEDGDL Y67
SQSTM1 (rat) PGGFQAHYRDEDGDL Y65
K91-ub
TMAMSYVkDDIFRIY
1 31
SQSTM1 (human) TMAMSYVkDDIFRIY K91-ub
SQSTM1 iso2 (human) _MAMSYVKDDIFRIY K7
SQSTM1 (mouse) TMAMSYVkDDIFRIY K91-ub
SQSTM1 (rat) TMAMSYVKDDIFRIY K89
T138
CNGPVVGTRYkCSVC
1 1
SQSTM1 (human) CNGPVVGtRYkCsVC T138-p
SQSTM1 iso2 (human) CNGPVVGTRYKCSVC T54
SQSTM1 (mouse) CNGPVVGTRYkCSVC T138
SQSTM1 (rat) CNGPVVGTRYKCSVC T135
K141-ub
PVVGTRYkCSVCPDy
0 38
SQSTM1 (human) PVVGtRYkCsVCPDy K141-ub
SQSTM1 iso2 (human) PVVGTRYKCSVCPDY K57
SQSTM1 (mouse) PVVGTRYkCSVCPDy K141-ub
SQSTM1 (rat) PVVGTRYKCSVCPDY K138
S143
VGTRYkCSVCPDyDL
0 1
SQSTM1 (human) VGtRYkCsVCPDyDL S143-p
SQSTM1 iso2 (human) VGTRYKCSVCPDYDL S59
SQSTM1 (mouse) VGTRYkCSVCPDyDL S143
SQSTM1 (rat) VGTRYKCSVCPDYDL S140
Y148-p
kCSVCPDyDLCsVCE
0 46
SQSTM1 (human) kCsVCPDyDLCsVCE Y148-p
SQSTM1 iso2 (human) KCSVCPDYDLCSVCE Y64
SQSTM1 (mouse) kCSVCPDyDLCsVCE Y148-p
SQSTM1 (rat) KCSVCPDYDLCSVCE Y145
S152-p
CPDyDLCsVCEGkGL
Upstream
0 9
Treatment
  • insulin
SQSTM1 (human) CPDyDLCsVCEGkGL S152-p
SQSTM1 iso2 (human) CPDYDLCSVCEGKGL S68
SQSTM1 (mouse) CPDyDLCsVCEGkGL S152-p
SQSTM1 (rat) CPDYDLCSVCEGKGL S149
K157-ub
LCsVCEGkGLHREHS
0 69
SQSTM1 (human) LCsVCEGkGLHRGHT K157-ub
SQSTM1 iso2 (human) LCSVCEGKGLHRGHT K73
SQSTM1 (mouse) LCsVCEGkGLHREHS K157-ub
SQSTM1 (rat) LCSVCEGKGLHREHS K154
K165-ub
GLHREHSkLIFPNPF
0 28
SQSTM1 (human) GLHRGHTkLAFPsPF K165-ub
SQSTM1 iso2 (human) GLHRGHTKLAFPSPF K81
SQSTM1 (mouse) GLHREHSkLIFPNPF K165-ub
SQSTM1 (rat) GLHREHSKLIFPNPF K162
N170
HSkLIFPNPFGHLSD
0 12
SQSTM1 (human) HTkLAFPsPFGHLsE S170-p
SQSTM1 iso2 (human) HTKLAFPSPFGHLSE S86
SQSTM1 (mouse) HSkLIFPNPFGHLSD N170
SQSTM1 (rat) HSKLIFPNPFGHLSD N167
S176
PNPFGHLSDsFSHSR
0 7
SQSTM1 (human) PsPFGHLsEGFSHsr S176-p
SQSTM1 iso2 (human) PSPFGHLSEGFSHSR S92
SQSTM1 (mouse) PNPFGHLSDsFSHSR S176
SQSTM1 (rat) PNPFGHLSDSFSHSR S173
S178-p
PFGHLSDsFSHSRWL
Upstream
0 5
Treatment
  • refeeding
SQSTM1 (human) PFGHLsEGFSHsrWL G178
SQSTM1 iso2 (human) PFGHLSEGFSHSRWL G94
SQSTM1 (mouse) PFGHLSDsFSHSRWL S178-p
SQSTM1 (rat) PFGHLSDSFSHSRWL S175
S182
LSDsFSHSRWLRKLK
0 3
SQSTM1 (human) LsEGFSHsrWLRkVk S182-p
SQSTM1 iso2 (human) LSEGFSHSRWLRKVK S98
SQSTM1 (mouse) LSDsFSHSRWLRKLK S182
SQSTM1 (rat) LSDSFSHSRWLRKLK S179
R183
SDsFSHSRWLRKLKH
0 2
SQSTM1 (human) sEGFSHsrWLRkVkH R183-m1
SQSTM1 iso2 (human) SEGFSHSRWLRKVKH R99
SQSTM1 (mouse) SDsFSHSRWLRKLKH R183
SQSTM1 (rat) SDSFSHSRWLRKLKH R180
K187
SHSRWLRKLKHGHFG
0 5
SQSTM1 (human) SHsrWLRkVkHGHFG K187-ub
SQSTM1 iso2 (human) SHSRWLRKVKHGHFG K103
SQSTM1 (mouse) SHSRWLRKLKHGHFG K187
SQSTM1 (rat) SHSRWLRKLKHGHFG K184
K189
SRWLRKLKHGHFGWP
1 13
SQSTM1 (human) srWLRkVkHGHFGWP K189-ub
SQSTM1 iso2 (human) SRWLRKVKHGHFGWP K105
SQSTM1 (mouse) SRWLRKLKHGHFGWP K189
SQSTM1 (rat) SRWLRKLKHGHFGWP K186
S207-p
MGPPGNWsPRPPRAG
Upstream
0 24
Treatment
  • insulin
SQSTM1 (human) MGPPGNWsPrPPRAG S207-p
SQSTM1 iso2 (human) MGPPGNWSPRPPRAG S123
SQSTM1 (mouse) MGPPGNWsPRPPRAG S207-p
SQSTM1 (rat) MGPPGNWSPRPPRAG S204
R209
PPGNWsPRPPRAGDG
0 1
SQSTM1 (human) PPGNWsPrPPRAGEA R209-m1
SQSTM1 iso2 (human) PPGNWSPRPPRAGEA R125
SQSTM1 (mouse) PPGNWsPRPPRAGDG R209
SQSTM1 (rat) PPGNWSPRPPRAGDG R206
T221
GDGRPCPTAESAsAP
0 1
SQSTM1 (human) GEARPGPtAEsAsGP T221-p
SQSTM1 iso2 (human) GEARPGPTAESASGP T137
SQSTM1 (mouse) GDGRPCPTAESAsAP T221
SQSTM1 (rat) GDGRPCPTAESASAP T218
S224
RPCPTAESAsAPPED
0 2
SQSTM1 (human) RPGPtAEsAsGPSED S224-p
SQSTM1 iso2 (human) RPGPTAESASGPSED S140
SQSTM1 (mouse) RPCPTAESAsAPPED S224
SQSTM1 (rat) RPCPTAESASAPSED S221
S226-p
CPTAESAsAPPEDPN
0 4
SQSTM1 (human) GPtAEsAsGPSEDPs S226-p
SQSTM1 iso2 (human) GPTAESASGPSEDPS S142
SQSTM1 (mouse) CPTAESAsAPPEDPN S226-p
SQSTM1 (rat) CPTAESASAPSEDPN S223
N233
sAPPEDPNVNFLKNV
0 7
SQSTM1 (human) sGPSEDPsVNFLKNV S233-p
SQSTM1 iso2 (human) SGPSEDPSVNFLKNV S149
SQSTM1 (mouse) sAPPEDPNVNFLKNV N233
SQSTM1 (rat) SAPSEDPNVNFLKNV N230
S249-p
ESVAAALsPLGIEVD
0 6
SQSTM1 (human) ESVAAALsPLGIEVD S249-p
SQSTM1 iso2 (human) ESVAAALSPLGIEVD S165
SQSTM1 (mouse) ESVAAALsPLGIEVD S249-p
SQSTM1 (rat) ESVAAALSPLGIEVD S246
K264
IDVEHGGKRsRLtPt
0 24
SQSTM1 (human) IDVEHGGkRsRLtPV K264-ub
SQSTM1 iso2 (human) IDVEHGGKRSRLTPV K180
SQSTM1 (mouse) IDVEHGGKRsRLtPt K264
SQSTM1 (rat) IDVEHGGKRSRLtPT K261
S266-p
VEHGGKRsRLtPttP
0 27
SQSTM1 (human) VEHGGkRsRLtPVsP S266-p
SQSTM1 iso2 (human) VEHGGKRSRLTPVSP S182
SQSTM1 (mouse) VEHGGKRsRLtPttP S266-p
SQSTM1 (rat) VEHGGKRSRLtPTSA S263
T269-p
GGKRsRLtPttPEss
Upstream
Downstream
2 205
SQSTM1 (human)
T269-p
SQSTM1 (mouse)
T269-p
SQSTM1 (rat)
T266-p
Effects on Biological Processes:
  • carcinogenesis, altered
  • cell cycle regulation
Regulatory protein:
  • Raptor (mouse)
Treatment
  • LPS
SQSTM1 (human) GGkRsRLtPVsPEss T269-p
SQSTM1 iso2 (human) GGKRSRLTPVSPESS T185
SQSTM1 (mouse) GGKRsRLtPttPEss T269-p
SQSTM1 (rat) GGKRSRLtPTSAESS T266-p
T271-p
KRsRLtPttPEssst
0 9
SQSTM1 (human) kRsRLtPVsPEssst V271
SQSTM1 iso2 (human) KRSRLTPVSPESSST V187
SQSTM1 (mouse) KRsRLtPttPEssst T271-p
SQSTM1 (rat) KRSRLtPTSAESSST T268
T272-p
RsRLtPttPEssstG
Upstream
Downstream
2 351
SQSTM1 (human)
S272-p
SQSTM1 (mouse)
T272-p
SQSTM1 (rat)
S269-p
Effects on Biological Processes:
  • carcinogenesis, altered
  • cell cycle regulation
Treatment
  • insulin
  • LPS
  • NAG-thiazoline
  • okadaic_acid
  • PUGNAc
SQSTM1 (human) RsRLtPVsPEssstE S272-p
SQSTM1 iso2 (human) RSRLTPVSPESSSTE S188
SQSTM1 (mouse) RsRLtPttPEssstG T272-p
SQSTM1 (rat) RSRLtPTSAESSSTG S269
S275-p
LtPttPEssstGTED
Upstream
0 35
Treatment
  • LPS
SQSTM1 (human) LtPVsPEssstEEks S275-p
SQSTM1 iso2 (human) LTPVSPESSSTEEKS S191
SQSTM1 (mouse) LtPttPEssstGTED S275-p
SQSTM1 (rat) LtPTSAESSSTGTED S272
S276-p
tPttPEssstGTEDK
0 37
SQSTM1 (human) tPVsPEssstEEksS S276-p
SQSTM1 iso2 (human) TPVSPESSSTEEKSS S192
SQSTM1 (mouse) tPttPEssstGTEDK S276-p
SQSTM1 (rat) tPTSAESSSTGTEDK S273
S277-p
PttPEssstGTEDKS
0 44
SQSTM1 (human) PVsPEssstEEksSs S277-p
SQSTM1 iso2 (human) PVSPESSSTEEKSSS S193
SQSTM1 (mouse) PttPEssstGTEDKS S277-p
SQSTM1 (rat) PTSAESSSTGTEDKS S274
T278-p
ttPEssstGTEDKSN
0 13
SQSTM1 (human) VsPEssstEEksSsQ T278-p
SQSTM1 iso2 (human) VSPESSSTEEKSSSQ T194
SQSTM1 (mouse) ttPEssstGTEDKSN T278-p
SQSTM1 (rat) TSAESSSTGTEDKSG T275
K283
sstGTEDKSNtQPSS
0 2
SQSTM1 (human) EssstEEksSsQPss K281-ub
SQSTM1 iso2 (human) ESSSTEEKSSSQPSS K197
SQSTM1 (mouse) sstGTEDKSNtQPSS K283
SQSTM1 (rat) SSTGTEDKSGTQPSS K280
S284
stGTEDKSNtQPSSC
0 5
SQSTM1 (human) ssstEEksSsQPssC S282-p
SQSTM1 iso2 (human) SSSTEEKSSSQPSSC S198
SQSTM1 (mouse) stGTEDKSNtQPSSC S284
SQSTM1 (rat) STGTEDKSGTQPSSC S281
T286-p
GTEDKSNtQPSSCSS
0 7
SQSTM1 (human) stEEksSsQPssCCs S284-p
SQSTM1 iso2 (human) STEEKSSSQPSSCCS S200
SQSTM1 (mouse) GTEDKSNtQPSSCSS T286-p
SQSTM1 (rat) GTEDKSGTQPSSCSS T283
S289
DKSNtQPSSCSSEVs
0 2
SQSTM1 (human) EksSsQPssCCsDPs S287-p
SQSTM1 iso2 (human) EKSSSQPSSCCSDPS S203
SQSTM1 (mouse) DKSNtQPSSCSSEVs S289
SQSTM1 (rat) DKSGTQPSSCSSEVs S286
S290
KSNtQPSSCSSEVsk
0 4
SQSTM1 (human) ksSsQPssCCsDPsk S288-p
SQSTM1 iso2 (human) KSSSQPSSCCSDPSK S204
SQSTM1 (mouse) KSNtQPSSCSSEVsk S290
SQSTM1 (rat) KSGTQPSSCSSEVsK S287
S293
tQPSSCSSEVskPDG
0 6
SQSTM1 (human) sQPssCCsDPskPGG S291-p
SQSTM1 iso2 (human) SQPSSCCSDPSKPGG S207
SQSTM1 (mouse) tQPSSCSSEVskPDG S293
SQSTM1 (rat) TQPSSCSSEVsKPDG S290
S296-p
SSCSSEVskPDGAGE
1 2
SQSTM1 (human) ssCCsDPskPGGNVE S294-p
SQSTM1 iso2 (human) SSCCSDPSKPGGNVE S210
SQSTM1 (mouse) SSCSSEVskPDGAGE S296-p
SQSTM1 (rat) SSCSSEVsKPDGAGE S293-p
K297-ub
SCSSEVskPDGAGEG
0 25
SQSTM1 (human) sCCsDPskPGGNVEG K295-ub
SQSTM1 iso2 (human) SCCSDPSKPGGNVEG K211
SQSTM1 (mouse) SCSSEVskPDGAGEG K297-ub
SQSTM1 (rat) SCSSEVsKPDGAGEG K294
S308-p
AGEGPAQsLTEQMkk
0 6
SQSTM1 (human) NVEGATQsLAEQMRk S306-p
SQSTM1 iso2 (human) NVEGATQSLAEQMRK S222
SQSTM1 (mouse) AGEGPAQsLTEQMkk S308-p
SQSTM1 (rat) AGEGPAQsLTEQMKK S305-p
K314-ub
QsLTEQMkkIALEsV
0 2
SQSTM1 (human) QsLAEQMRkIALEsE R312
SQSTM1 iso2 (human) QSLAEQMRKIALESE R228
SQSTM1 (mouse) QsLTEQMkkIALEsV K314-ub
SQSTM1 (rat) QsLTEQMKKIALESV K311
K315-ub
sLTEQMkkIALEsVG
0 19
SQSTM1 (human) sLAEQMRkIALEsEG K313-ub
SQSTM1 iso2 (human) SLAEQMRKIALESEG K229
SQSTM1 (mouse) sLTEQMkkIALEsVG K315-ub
SQSTM1 (rat) sLTEQMKKIALESVG K312
S320-p
MkkIALEsVGQPEEQ
Upstream
0 3
Regulatory protein:
  • MPRIP (mouse)
SQSTM1 (human) MRkIALEsEGRPEEQ S318-p
SQSTM1 iso2 (human) MRKIALESEGRPEEQ S234
SQSTM1 (mouse) MkkIALEsVGQPEEQ S320-p
SQSTM1 (rat) MKKIALESVGQPEEL S317
S330-p
QPEEQMEsGNCsGGD
0 23
SQSTM1 (human) RPEEQMEsDNCsGGD S328-p
SQSTM1 iso2 (human) RPEEQMESDNCSGGD S244
SQSTM1 (mouse) QPEEQMEsGNCsGGD S330-p
SQSTM1 (rat) QPEELMESDNCSGGD S327
S334-p
QMEsGNCsGGDDDWt
Upstream
0 36
Treatment
  • IFN-gamma
  • refeeding
SQSTM1 (human) QMEsDNCsGGDDDWt S332-p
SQSTM1 iso2 (human) QMESDNCSGGDDDWT S248
SQSTM1 (mouse) QMEsGNCsGGDDDWt S334-p
SQSTM1 (rat) LMESDNCSGGDDDWT S331
T341-p
sGGDDDWtHLSsKEV
0 4
SQSTM1 (human) sGGDDDWtHLsskEV T339-p
SQSTM1 iso2 (human) SGGDDDWTHLSSKEV T255
SQSTM1 (mouse) sGGDDDWtHLSsKEV T341-p
SQSTM1 (rat) SGGDDDWTHLSSKEV T338
S344
DDDWtHLSsKEVDPs
0 5
SQSTM1 (human) DDDWtHLsskEVDPs S342-p
SQSTM1 iso2 (human) DDDWTHLSSKEVDPS S258
SQSTM1 (mouse) DDDWtHLSsKEVDPs S344
SQSTM1 (rat) DDDWTHLSSKEVDPs S341
S345-p
DDWtHLSsKEVDPsT
0 4
SQSTM1 (human) DDWtHLsskEVDPst S343-p
SQSTM1 iso2 (human) DDWTHLSSKEVDPST S259
SQSTM1 (mouse) DDWtHLSsKEVDPsT S345-p
SQSTM1 (rat) DDWTHLSSKEVDPsT S342
K346
DWtHLSsKEVDPsTG
0 1
SQSTM1 (human) DWtHLsskEVDPstG K344-ac
SQSTM1 iso2 (human) DWTHLSSKEVDPSTG K260
SQSTM1 (mouse) DWtHLSsKEVDPsTG K346
SQSTM1 (rat) DWTHLSSKEVDPsTG K343
K346
DWtHLSsKEVDPsTG
0 1
SQSTM1 (human) DWtHLsskEVDPstG K344-ub
SQSTM1 iso2 (human) DWTHLSSKEVDPSTG K260
SQSTM1 (mouse) DWtHLSsKEVDPsTG K346
SQSTM1 (rat) DWTHLSSKEVDPsTG K343
S351-p
SsKEVDPsTGELQsL
Upstream
Downstream
23 1
SQSTM1 (human)
S349-p
SQSTM1 iso2 (human)
S265-p
SQSTM1 (mouse)
S351-p
SQSTM1 (rat)
S348-p
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
Effects on Biological Processes:
  • autophagy, induced
  • transcription, induced
  • transcription, inhibited
Kinase, in vitro:
  • mTOR (human)
Putative in vivo kinases:
  • AMPKA1 (human)
  • TAK1 (mouse)
Regulatory protein:
  • AMPKA1 (mouse)
  • RPT2 (mouse)
Treatment
  • bacterial infection
  • bafilomycin_A
  • deferoxamine
  • ezetimibe
  • glucose_oxidase
  • high-fat diet
  • methionine- and choline-deficient diet
  • oleic_acid
  • palmitoleic_acid
SQSTM1 (human) sskEVDPstGELQsL S349-p
SQSTM1 iso2 (human) SSKEVDPSTGELQSL S265
SQSTM1 (mouse) SsKEVDPsTGELQsL S351-p
SQSTM1 (rat) SSKEVDPsTGELQsL S348-p
T352
sKEVDPsTGELQsLQ
0 1
SQSTM1 (human) skEVDPstGELQsLQ T350-p
SQSTM1 iso2 (human) SKEVDPSTGELQSLQ T266
SQSTM1 (mouse) sKEVDPsTGELQsLQ T352
SQSTM1 (rat) SKEVDPsTGELQsLQ T349
S357-p
PsTGELQsLQMPEsE
Upstream
0 16
Treatment
  • insulin
  • LY294002
  • refeeding
SQSTM1 (human) PstGELQsLQMPEsE S355-p
SQSTM1 iso2 (human) PSTGELQSLQMPESE S271
SQSTM1 (mouse) PsTGELQsLQMPEsE S357-p
SQSTM1 (rat) PsTGELQsLQMPEsE S354-p
S363-p
QsLQMPEsEGPssLD
0 13
SQSTM1 (human) QsLQMPEsEGPssLD S361-p
SQSTM1 iso2 (human) QSLQMPESEGPSSLD S277
SQSTM1 (mouse) QsLQMPEsEGPssLD S363-p
SQSTM1 (rat) QsLQMPEsEGPSsLD S360-p
S367-p
MPEsEGPssLDPsQE
0 10
SQSTM1 (human) MPEsEGPssLDPsQE S365-p
SQSTM1 iso2 (human) MPESEGPSSLDPSQE S281
SQSTM1 (mouse) MPEsEGPssLDPsQE S367-p
SQSTM1 (rat) MPEsEGPSsLDPSQE S364
S368-p
PEsEGPssLDPsQEG
Upstream
1 28
Treatment
  • refeeding
SQSTM1 (human) PEsEGPssLDPsQEG S366-p
SQSTM1 iso2 (human) PESEGPSSLDPSQEG S282
SQSTM1 (mouse) PEsEGPssLDPsQEG S368-p
SQSTM1 (rat) PEsEGPSsLDPSQEG S365-p
S372-p
GPssLDPsQEGPTGL
0 10
SQSTM1 (human) GPssLDPsQEGPtGL S370-p
SQSTM1 iso2 (human) GPSSLDPSQEGPTGL S286
SQSTM1 (mouse) GPssLDPsQEGPTGL S372-p
SQSTM1 (rat) GPSsLDPSQEGPTGL S369
T377
DPsQEGPTGLKEAAL
0 3
SQSTM1 (human) DPsQEGPtGLkEAAL T375-p
SQSTM1 iso2 (human) DPSQEGPTGLKEAAL T291
SQSTM1 (mouse) DPsQEGPTGLKEAAL T377
SQSTM1 (rat) DPSQEGPTGLKEAAL T374
K380
QEGPTGLKEAALYPH
0 2
SQSTM1 (human) QEGPtGLkEAALyPH K378-ac
SQSTM1 iso2 (human) QEGPTGLKEAALYPH K294
SQSTM1 (mouse) QEGPTGLKEAALYPH K380
SQSTM1 (rat) QEGPTGLKEAALYPH K377
K380
QEGPTGLKEAALYPH
0 1
SQSTM1 (human) QEGPtGLkEAALyPH K378-ub
SQSTM1 iso2 (human) QEGPTGLKEAALYPH K294
SQSTM1 (mouse) QEGPTGLKEAALYPH K380
SQSTM1 (rat) QEGPTGLKEAALYPH K377
Y385
GLKEAALYPHLPPEA
0 3
SQSTM1 (human) GLkEAALyPHLPPEA Y383-p
SQSTM1 iso2 (human) GLKEAALYPHLPPEA Y299
SQSTM1 (mouse) GLKEAALYPHLPPEA Y385
SQSTM1 (rat) GLKEAALYPHLPPEA Y382
S405-p
ESLSQMLsMGFsDEG
Upstream
Downstream
12 5
SQSTM1 (human)
S403-p
SQSTM1 (mouse)
S405-p
SQSTM1 (rat)
S402-p
Effects on Biological Processes:
  • autophagy, induced
Regulatory protein:
  • Huntingtin (human)
SQSTM1 (human) ESLSQMLsMGFsDEG S403-p
SQSTM1 iso2 (human) ESLSQMLSMGFSDEG S319
SQSTM1 (mouse) ESLSQMLsMGFsDEG S405-p
SQSTM1 (rat) ESLSQMLsMGFSDEG S402-p
S409-p
QMLsMGFsDEGGWLT
Upstream
Downstream
3 1
Effects on Modified Protein
  • protein degradation
  • ubiquitination
Effects on Biological Processes:
  • autophagy, induced
Kinase, in vitro:
  • ULK1 (human)
Putative in vivo kinases:
  • ULK1 (human)
Regulatory protein:
  • Huntingtin (human)
Treatment
  • MG132
SQSTM1 (human) QMLsMGFsDEGGWLT S407-p
SQSTM1 iso2 (human) QMLSMGFSDEGGWLT S323
SQSTM1 (mouse) QMLsMGFsDEGGWLT S409-p
SQSTM1 (rat) QMLsMGFSDEGGWLT S406
K422-ub
LTRLLQTkNYDIGAA
2 30
SQSTM1 (human) LTRLLQTkNYDIGAA K420-ub
SQSTM1 iso2 (human) LTRLLQTKNYDIGAA K336
SQSTM1 (mouse) LTRLLQTkNYDIGAA K422-ub
SQSTM1 (rat) LTRLLQTKNYDIGAA K419
T432
DIGAALDTIQYSkHP
0 1
SQSTM1 (human) DIGAALDtIQyskHP T430-p
SQSTM1 iso2 (human) DIGAALDTIQYSKHP T346
SQSTM1 (mouse) DIGAALDTIQYSkHP T432
SQSTM1 (rat) DIGAALDTIQYSKHP T429
Y435
AALDTIQYSkHPPPL
1 3
SQSTM1 (human) AALDtIQyskHPPPL Y433-p
SQSTM1 iso2 (human) AALDTIQYSKHPPPL Y349
SQSTM1 (mouse) AALDTIQYSkHPPPL Y435
SQSTM1 (rat) AALDTIQYSKHPPPL Y432
S436
ALDTIQYSkHPPPL_
0 2
SQSTM1 (human) ALDtIQyskHPPPL_ S434-p
SQSTM1 iso2 (human) ALDTIQYSKHPPPL_ S350
SQSTM1 (mouse) ALDTIQYSkHPPPL_ S436
SQSTM1 (rat) ALDTIQYSKHPPPL_ S433
K437-ub
LDTIQYSkHPPPL__
0 103
SQSTM1 (human) LDtIQyskHPPPL__ K435-ub
SQSTM1 iso2 (human) LDTIQYSKHPPPL__ K351
SQSTM1 (mouse) LDTIQYSkHPPPL__ K437-ub
SQSTM1 (rat) LDTIQYSKHPPPL__ K434