Other Species / Isoforms
  HDAC4 (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

 HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
T36-p
PSTVDVAtALPLQVA
0 1
HDAC4 (human) PSTVDVAtALPLQVA T36-p
HDAC4 (mouse) PSTVDVATALPLQVA T36
HDAC4 (rat) PSTVDVATALPLQVA T36
S45-p
LPLQVAPsAVPMDLR
0 1
HDAC4 (human) LPLQVAPsAVPMDLR S45-p
HDAC4 (mouse) LPLQVAPTAVPMDLR T45
HDAC4 (rat) LPLQVAPAAVPMDLR A45
S58-p
LRLDHQFsLPVAEPA
0 5
HDAC4 (human) LRLDHQFsLPVAEPA S58-p
HDAC4 (mouse) LRLDHQFSLPLEPAL S58
HDAC4 (rat) LRLDHQFSLPLEPAL S58
K79-ub
QQELLALkQKQQIQR
0 1
HDAC4 (human) QQELLALkQKQQIQR K79-ub
HDAC4 (mouse) QQELLALKQKQQIQR K78
HDAC4 (rat) QQELLALKQKQQIQR K78
K151-ub
EKQHREQkLQQLKNK
0 1
HDAC4 (human) EKQHREQkLQQLKNK K151-ub
HDAC4 (mouse) EKQHREQKLQQLKNK K150
HDAC4 (rat) EKQHREQKLQQLKNK K150
S168-p
GKESAVAsTEVKMKL
0 1
HDAC4 (human) GKESAVAsTEVKMKL S168-p
HDAC4 (mouse) GKESAVASTEVkMKL S167
HDAC4 (rat) GKESAVASTEVKMKL S167
K172
AVAsTEVKMKLQEFV
0 1
HDAC4 (human) AVAsTEVKMKLQEFV K172
HDAC4 (mouse) AVASTEVkMKLQEFV K171-ac
HDAC4 (rat) AVASTEVKMKLQEFV K171
S196-p
RNLNHCIsSDPRYWY
0 3
HDAC4 (human) RNLNHCIsSDPRYWY S196-p
HDAC4 (mouse) RNLNHCIsSDPRYWY S195-p
HDAC4 (rat) RNLNHCMSSDPRYWY S195
S210-p
YGKTQHSsLDQSsPP
Upstream
Downstream
1 4
Effects on Biological Processes:
  • transcription, altered
Kinase, in vitro:
  • CAMK2D (human)
Putative in vivo kinases:
  • CAMK2D (human)
HDAC4 (human) YGKTQHSsLDQSsPP S210-p
HDAC4 (mouse) YGKTQHSsLDQSsPP S209-p
HDAC4 (rat) YGKTQHSSLDQSSPP S209
S215-p
HSsLDQSsPPQSGVS
0 2
HDAC4 (human) HSsLDQSsPPQSGVS S215-p
HDAC4 (mouse) HSsLDQSsPPQSGVS S214-p
HDAC4 (rat) HSSLDQSSPPQSGVS S214
Y225-p
QSGVSTSyNHPVLGM
0 1
HDAC4 (human) QSGVSTSyNHPVLGM Y225-p
HDAC4 (mouse) QSGVSASYNHPVLGM Y224
HDAC4 (rat) QSGVSASYNHPVLGM Y224
Y233-p
NHPVLGMyDAkDDFP
0 1
HDAC4 (human) NHPVLGMyDAkDDFP Y233-p
HDAC4 (mouse) NHPVLGMYDAKDDFP Y232
HDAC4 (rat) NHPVLGMYDAKDDFP Y232
K236-ac
VLGMyDAkDDFPLRK
0 1
HDAC4 (human) VLGMyDAkDDFPLRK K236-ac
HDAC4 (mouse) VLGMYDAKDDFPLRK K235
HDAC4 (rat) VLGMYDAKDDFPLRK K235
S246-p
FPLRKTAsEPNLKLR
Upstream
Downstream
12 48
HDAC4 (human)
S246-p
HDAC4 (mouse)
S245-p
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
  • protein degradation
  • protein stabilization
Effects on Biological Processes:
  • apoptosis, inhibited
  • carcinogenesis, induced
  • cell cycle regulation
  • transcription, altered
  • transcription, induced
Kinase, in vitro:
  • MARK2 (human)
Putative in vivo kinases:
  • MARK2 (human)
  • TAK1 (human)
Regulatory protein:
  • NAC1 (human)
Treatment
  • cAMP_analog
  • Go_6976
  • hypoxia
  • KN-93
  • okadaic_acid
  • PTH
  • siRNA
  • staurosporine
  • VEGF
HDAC4 (human) FPLRKTAsEPNLKLR S246-p
HDAC4 (mouse) FPLRKTAsEPNLKLR S245-p
HDAC4 (rat) FPLRKTAsEPNLKLR S245-p
S265-p
QKVAERRssPLLRRK
Upstream
Downstream
4 15
Effects on Modified Protein
  • activity, induced
  • intracellular localization
Effects on Biological Processes:
  • transcription, inhibited
Kinase, in vitro:
  • PKACA (human)
Putative in vivo kinases:
  • PKACA (human)
  • PKACA (mouse)
Treatment
  • angiotensin_2
  • cAMP_analog
  • H-89
  • hesperadin
  • isoproterenol
  • N6-benzoyl-cAMP
  • NKH_477
  • nocodazole
  • propranolol
  • Rp-cAMPS
  • siRNA
HDAC4 (human) QKVAERRssPLLRRK S265-p
HDAC4 (mouse) QKVAERRssPLLRRk S264-p
HDAC4 (rat) QKVAERRSsPLLRRK S264
S266-p
KVAERRssPLLRRKD
Upstream
Downstream
4 21
Effects on Modified Protein
  • activity, induced
  • intracellular localization
Effects on Biological Processes:
  • transcription, inhibited
Kinase, in vitro:
  • PKACA (human)
Putative in vivo kinases:
  • PKACA (human)
  • PKACA (mouse)
Treatment
  • cAMP_analog
  • H-89
  • isoproterenol
  • N6-benzoyl-cAMP
  • NKH_477
  • nocodazole
  • propranolol
  • Rp-cAMPS
  • siRNA
HDAC4 (human) KVAERRssPLLRRKD S266-p
HDAC4 (mouse) KVAERRssPLLRRkD S265-p
HDAC4 (rat) KVAERRSsPLLRRKD S265-p
K272
ssPLLRRKDGPVVtA
0 1
HDAC4 (human) ssPLLRRKDGPVVtA K272
HDAC4 (mouse) ssPLLRRkDGPVATA K271-ub
HDAC4 (rat) SsPLLRRKDGPVATA K271
T278-p
RKDGPVVtALKKRPL
0 1
HDAC4 (human) RKDGPVVtALKKRPL T278-p
HDAC4 (mouse) RkDGPVATALkkRPL T277
HDAC4 (rat) RKDGPVATALKKRPL T277
K281
GPVVtALKKRPLDVT
0 1
HDAC4 (human) GPVVtALKKRPLDVT K281
HDAC4 (mouse) GPVATALkkRPLDVT K280-ub
HDAC4 (rat) GPVATALKKRPLDVT K280
K282
PVVtALKKRPLDVTD
0 1
HDAC4 (human) PVVtALKKRPLDVTD K282
HDAC4 (mouse) PVATALkkRPLDVTD K281-ub
HDAC4 (rat) PVATALKKRPLDVTD K281
S298-p
ACSSAPGsGPSsPNN
Upstream
Downstream
2 0
Effects on Modified Protein
  • intracellular localization
  • protein degradation
  • ubiquitination
Effects on Biological Processes:
  • cell motility, altered
Kinase, in vitro:
  • GSK3B (human)
Putative in vivo kinases:
  • GSK3B (human)
HDAC4 (human) ACSSAPGsGPSsPNN S298-p
HDAC4 (mouse) ACSSAPGSGPSSPNS S297
HDAC4 (rat) ACSSAPGSGPSSPNS S297
S302-p
APGsGPSsPNNSSGS
Upstream
Downstream
1 0
Effects on Modified Protein
  • intracellular localization
  • protein degradation
  • ubiquitination
Effects on Biological Processes:
  • cell motility, altered
Kinase, in vitro:
  • GSK3B (human)
Putative in vivo kinases:
  • GSK3B (human)
HDAC4 (human) APGsGPSsPNNSSGS S302-p
HDAC4 (mouse) APGSGPSSPNSSSGN S301
HDAC4 (rat) APGSGPSSPNSSSGN S301
S339-p
RLVAREGsAAPLPLY
0 1
HDAC4 (human) RLVAREGsAAPLPLY S339-p
HDAC4 (mouse) RLVTREGSVAPLPLY S338
HDAC4 (rat) RLVTREGSVAPLPLY S338
S348-p
APLPLYTsPsLPNIT
0 1
HDAC4 (human) APLPLYTsPsLPNIT S348-p
HDAC4 (mouse) APLPLYTSPSLPNIT S347
HDAC4 (rat) APLPLYTSPSLPNIT S347
S350-p
LPLYTsPsLPNITLG
Downstream
1 6
Effects on Modified Protein
  • molecular association, regulation
HDAC4 (human) LPLYTsPsLPNITLG S350-p
HDAC4 (mouse) LPLYTSPSLPNITLG S349
HDAC4 (rat) LPLYTSPSLPNITLG S349
T391-p
RLSLFPGtHLtPyLS
0 1
HDAC4 (human) RLSLFPGtHLtPyLS T391-p
HDAC4 (mouse) QRILFPGTHLTPYLS T389
HDAC4 (rat) RISLFPGTHLTPYLS T390
T394-p
LFPGtHLtPyLSTsP
0 2
HDAC4 (human) LFPGtHLtPyLSTsP T394-p
HDAC4 (mouse) LFPGTHLTPYLSTSP T392
HDAC4 (rat) LFPGTHLTPYLSTSP T393
Y396-p
PGtHLtPyLSTsPLE
0 1
HDAC4 (human) PGtHLtPyLSTsPLE Y396-p
HDAC4 (mouse) PGTHLTPYLSTSPLE Y394
HDAC4 (rat) PGTHLTPYLSTSPLE Y395
S400-p
LtPyLSTsPLERDGG
0 4
HDAC4 (human) LtPyLSTsPLERDGG S400-p
HDAC4 (mouse) LTPYLSTSPLERDGA S398
HDAC4 (rat) LTPYLSTSPLERDGG S399
T465-p
QHRPLGRtQsAPLPQ
0 3
HDAC4 (human) QHRPLGRtQsAPLPQ T465-p
HDAC4 (mouse) QHRPLGRtQsAPLPQ T463-p
HDAC4 (rat) QHRPLGRTQsAPLPQ T464
S467-p
RPLGRtQsAPLPQNA
Upstream
Downstream
6 40
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
Effects on Biological Processes:
  • apoptosis, inhibited
  • carcinogenesis, induced
  • cell cycle regulation
  • transcription, altered
  • transcription, induced
Kinase, in vitro:
  • MARK2 (human)
Treatment
  • cAMP_analog
  • EGF
  • Go_6976
  • ischemia
  • KN-93
  • VEGF
HDAC4 (human) RPLGRtQsAPLPQNA S467-p
HDAC4 (mouse) RPLGRtQsAPLPQNA S465-p
HDAC4 (rat) RPLGRTQsAPLPQNA S466-p
K494-ub
QQFLEKHkQQFQQQQ
0 1
HDAC4 (human) QQFLEKHkQQFQQQQ K494-ub
HDAC4 (mouse) QQFLEKHKQQFQQQQ K492
HDAC4 (rat) QQFLEKHKQQFQQQQ K493
Y540-p
QALLDEPyLDRLPGQ
0 1
HDAC4 (human) QALLDEPyLDRLPGQ Y540-p
HDAC4 (mouse) QALLDEPYLDRLPGQ Y538
HDAC4 (rat) QALLDEPYLDRLPGQ Y539
K548-ac
LDRLPGQkEAHAQAG
0 1
HDAC4 (human) LDRLPGQkEAHAQAG K548-ac
HDAC4 (mouse) LDRLPGQKEPSLAGV K546
HDAC4 (rat) LDRLPGQKEPSLAGV K547
K559-sm
AQAGVQVkQEPIEsD
Upstream
Downstream
2 1
Effects on Modified Protein
  • acetylation
  • enzymatic activity, induced
  • protein degradation
  • ubiquitination
Effects on Biological Processes:
  • apoptosis, inhibited
  • transcription, inhibited
Regulatory protein:
  • CAMK1A (human)
  • PIAS1 (human)
  • PIAS3 (human)
HDAC4 (human) AQAGVQVkQEPIEsD K559-sm
HDAC4 (mouse) SLAGVQVKQEPIEsE K556
HDAC4 (rat) SLAGVQVKQEPIEsE K557
S565-p
VkQEPIEsDEEEAEP
0 80
HDAC4 (human) VkQEPIEsDEEEAEP S565-p
HDAC4 (mouse) VKQEPIEsEEEEAEA S562-p
HDAC4 (rat) VKQEPIEsEEEEVEA S563-p
S584-p
EPGQRQPsEQELLFR
Upstream
Downstream
1 4
Effects on Modified Protein
  • activity, induced
Effects on Biological Processes:
  • transcription, inhibited
Kinase, in vitro:
  • PKACA (human)
Putative in vivo kinases:
  • PKACA (human)
Treatment
  • cAMP_analog
  • H-89
  • NKH_477
  • siRNA
HDAC4 (human) EPGQRQPsEQELLFR S584-p
HDAC4 (mouse) EPGQRPATEQELLFR T581
HDAC4 (rat) EPSQRPATEQELLFR T582
S611-p
QLRNYQAsMEAAGIP
0 2
HDAC4 (human) QLRNYQAsMEAAGIP S611-p
HDAC4 (mouse) QLRNYQASMEAAGIP S608
HDAC4 (rat) QLRNYQASMEAAGIP S609
S632-p
RPLSRAQssPAsAtF
Upstream
Downstream
11 110
HDAC4 (human)
S632-p
HDAC4 (mouse)
S629-p
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
  • protein stabilization
Effects on Biological Processes:
  • transcription, altered
Putative in vivo kinases:
  • PKCA (human)
Regulatory protein:
  • AMPKA2 (mouse)
  • PKD1 (human)
Treatment
  • cAMP_analog
  • exercise
  • Go_6976
  • KN-93
  • LRRK2-IN-1
  • okadaic_acid
  • PGE2
  • PTH
  • VEGF
HDAC4 (human) RPLSRAQssPAsAtF S632-p
HDAC4 (mouse) RPLSRAQssPASATF S629-p
HDAC4 (rat) RPLSRAQsSPASATF S630-p
S633-p
PLSRAQssPAsAtFP
0 12
HDAC4 (human) PLSRAQssPAsAtFP S633-p
HDAC4 (mouse) PLSRAQssPASATFP S630-p
HDAC4 (rat) PLSRAQsSPASATFP S631
S636-p
RAQssPAsAtFPVsV
0 6
HDAC4 (human) RAQssPAsAtFPVsV S636-p
HDAC4 (mouse) RAQssPASATFPMSV S633
HDAC4 (rat) RAQsSPASATFPMSV S634
T638-p
QssPAsAtFPVsVQE
0 1
HDAC4 (human) QssPAsAtFPVsVQE T638-p
HDAC4 (mouse) QssPASATFPMSVQE T635
HDAC4 (rat) QsSPASATFPMSVQE T636
S642-p
AsAtFPVsVQEPPtK
0 1
HDAC4 (human) AsAtFPVsVQEPPtK S642-p
HDAC4 (mouse) ASATFPMSVQEPPTK S639
HDAC4 (rat) ASATFPMSVQEPPTK S640
T648-p
VsVQEPPtKPRFTTG
0 1
HDAC4 (human) VsVQEPPtKPRFTTG T648-p
HDAC4 (mouse) MSVQEPPTKPRFTTG T645
HDAC4 (rat) MSVQEPPTKPRFTTG T646
K705-ub
CECIRGRkATLEELQ
0 1
HDAC4 (human) CECIRGRkATLEELQ K705-ub
HDAC4 (mouse) CECIRGRKATLEELQ K702
HDAC4 (rat) CECIRGRKAtLEELQ K703
T707
CIRGRkATLEELQTV
1 0
HDAC4 (human) CIRGRkATLEELQTV T707
HDAC4 (mouse) CIRGRKATLEELQTV T704
HDAC4 (rat) CIRGRKAtLEELQTV T705-p
K737-ub
RQKLDSKkLLGsLAs
0 1
HDAC4 (human) RQKLDSKkLLGsLAs K737-ub
HDAC4 (mouse) gap -
HDAC4 (rat) gap -
S741-p
DSKkLLGsLAsVFVR
0 2
HDAC4 (human) DSKkLLGsLAsVFVR S741-p
HDAC4 (mouse) NRQKLDSsLTsVFVR S733-p
HDAC4 (rat) NRQKLDSSLTSVFVR S734
S744-p
kLLGsLAsVFVRLPC
0 2
HDAC4 (human) kLLGsLAsVFVRLPC S744-p
HDAC4 (mouse) KLDSsLTsVFVRLPC S736-p
HDAC4 (rat) KLDSSLTSVFVRLPC S737
S1025-p
EKVMEIHskYWRCLQ
0 1
HDAC4 (human) EKVMEIHskYWRCLQ S1025-p
HDAC4 (mouse) EKVMDIHSKYWRCLQ S1017
HDAC4 (rat) EKVMGIHSEYWRCLQ S1018
K1026-ub
KVMEIHskYWRCLQR
0 2
HDAC4 (human) KVMEIHskYWRCLQR K1026-ub
HDAC4 (mouse) KVMDIHSKYWRCLQR K1018
HDAC4 (rat) KVMGIHSEYWRCLQR E1019
T1057-p
NEEAETVtAMAsLSV
0 1
HDAC4 (human) NEEAETVtAMAsLSV T1057-p
HDAC4 (mouse) KEEAETVTAMASLSV T1049
HDAC4 (rat) NEEAETVTAMASLSV T1050
S1061-p
ETVtAMAsLSVGVKP
0 1
HDAC4 (human) ETVtAMAsLSVGVKP S1061-p
HDAC4 (mouse) ETVTAMASLSVGVKP S1053
HDAC4 (rat) ETVTAMASLSVGVKP S1054