Other Species / Isoforms
  ERF (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

 HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
K2-m1
______MktPADtGF
0 1
ERF (human) ______MktPADtGF K2-m1
ERF iso2 (human) gap -
ERF (mouse) ______MKtPADTGF K2
ERF (rat) ______MKTPADTGF K2
K2-ub
______MktPADtGF
0 1
ERF (human) ______MktPADtGF K2-ub
ERF iso2 (human) gap -
ERF (mouse) ______MKtPADTGF K2
ERF (rat) ______MKTPADTGF K2
T3-p
_____MktPADtGFA
Upstream
0 19
Treatment
  • ischemia
  • selumetinib
  • vemurafenib
ERF (human) _____MktPADtGFA T3-p
ERF iso2 (human) gap -
ERF (mouse) _____MKtPADTGFA T3-p
ERF (rat) _____MKTPADTGFA T3
T7-p
_MktPADtGFAFPDW
0 2
ERF (human) _MktPADtGFAFPDW T7-p
ERF iso2 (human) gap -
ERF (mouse) _MKtPADTGFAFPDW T7
ERF (rat) _MKTPADTGFAFPDW T7
Y16-p
FAFPDWAykPEssPG
0 2
ERF (human) FAFPDWAykPEssPG Y16-p
ERF iso2 (human) gap -
ERF (mouse) FAFPDWAYKPEssPG Y16
ERF (rat) FAFPDWAYKPESSPG Y16
K17-ub
AFPDWAykPEssPGs
0 2
ERF (human) AFPDWAykPEssPGs K17-ub
ERF iso2 (human) gap -
ERF (mouse) AFPDWAYKPEssPGs K17
ERF (rat) AFPDWAYKPESSPGS K17
S20-p
DWAykPEssPGsRQI
0 3
ERF (human) DWAykPEssPGsRQI S20-p
ERF iso2 (human) gap -
ERF (mouse) DWAYKPEssPGsRQI S20-p
ERF (rat) DWAYKPESSPGSRQI S20
S21-p
WAykPEssPGsRQIQ
Upstream
0 8
Treatment
  • Y27632
ERF (human) WAykPEssPGsRQIQ S21-p
ERF iso2 (human) gap -
ERF (mouse) WAYKPEssPGsRQIQ S21-p
ERF (rat) WAYKPESSPGSRQIQ S21
S24-p
kPEssPGsRQIQLWH
0 5
ERF (human) kPEssPGsRQIQLWH S24-p
ERF iso2 (human) gap -
ERF (mouse) KPEssPGsRQIQLWH S24-p
ERF (rat) KPESSPGSRQIQLWH S24
N77
RKCKPQMNYDKLSRA
0 1
ERF (human) RKCKPQMNYDKLSRA N77
ERF iso2 (human) ______MnYDKLSRA N2-n-ub
ERF (mouse) RKCKPQMNYDKLSRA N77
ERF (rat) RKCKPQMNYDKLSRA N77
S131-p
AGGAVPQsAPPVPSG
Upstream
0 9
Treatment
  • selumetinib
  • vemurafenib
ERF (human) AGGAVPQsAPPVPSG S131-p
ERF iso2 (human) AGGAVPQSAPPVPSG S56
ERF (mouse) AGGAVPQsAPPVPSG S131-p
ERF (rat) AGGAVPQSAPPVPSG S131
S147-p
SHFRFPPstPsEVLs
0 2
ERF (human) SHFRFPPstPsEVLs S147-p
ERF iso2 (human) SHFRFPPSTPSEVLS S72
ERF (mouse) SHFRFPPSTPSEVLS S147
ERF (rat) SHFRFPPSTPSEVLS S147
T148-p
HFRFPPstPsEVLsP
0 3
ERF (human) HFRFPPstPsEVLsP T148-p
ERF iso2 (human) HFRFPPSTPSEVLSP T73
ERF (mouse) HFRFPPSTPSEVLSP T148
ERF (rat) HFRFPPSTPSEVLSP T148
S150-p
RFPPstPsEVLsPtE
0 7
ERF (human) RFPPstPsEVLsPtE S150-p
ERF iso2 (human) RFPPSTPSEVLSPTE S75
ERF (mouse) RFPPSTPSEVLSPtE S150
ERF (rat) RFPPSTPSEVLSPTE S150
S154-p
stPsEVLsPtEDPRs
Upstream
0 13
Treatment
  • selumetinib
ERF (human) stPsEVLsPtEDPRs S154-p
ERF iso2 (human) STPSEVLSPTEDPRS S79
ERF (mouse) STPSEVLSPtEDPRs S154
ERF (rat) STPSEVLSPTEDPRS S154
T156-p
PsEVLsPtEDPRsPP
0 12
ERF (human) PsEVLsPtEDPRsPP T156-p
ERF iso2 (human) PSEVLSPTEDPRSPP T81
ERF (mouse) PSEVLSPtEDPRsPP T156-p
ERF (rat) PSEVLSPTEDPRSPP T156
S161-p
sPtEDPRsPPACssS
Upstream
Downstream
1 15
Effects on Modified Protein
  • intracellular localization
Effects on Biological Processes:
  • cell cycle regulation
Kinase, in vitro:
  • ERK2 (human)
Putative in vivo kinases:
  • ERK2 (human)
Treatment
  • PD98059
  • selumetinib
  • serum
  • vemurafenib
ERF (human) sPtEDPRsPPACssS S161-p
ERF iso2 (human) SPTEDPRSPPACSSS S86
ERF (mouse) SPtEDPRsPPACSSS S161-p
ERF (rat) SPTEDPRSPPACSSS S161
S166-p
PRsPPACssSsssLF
0 1
ERF (human) PRsPPACssSsssLF S166-p
ERF iso2 (human) PRSPPACSSSSSSLF S91
ERF (mouse) PRsPPACSSSSSSLF S166
ERF (rat) PRSPPACSSSSSSLF S166
S167-p
RsPPACssSsssLFS
0 1
ERF (human) RsPPACssSsssLFS S167-p
ERF iso2 (human) RSPPACSSSSSSLFS S92
ERF (mouse) RsPPACSSSSSSLFS S167
ERF (rat) RSPPACSSSSSSLFS S167
S169-p
PPACssSsssLFSAV
0 3
ERF (human) PPACssSsssLFSAV S169-p
ERF iso2 (human) PPACSSSSSSLFSAV S94
ERF (mouse) PPACSSSSSSLFSAV S169
ERF (rat) PPACSSSSSSLFSAV S169
S170-p
PACssSsssLFSAVV
0 1
ERF (human) PACssSsssLFSAVV S170-p
ERF iso2 (human) PACSSSSSSLFSAVV S95
ERF (mouse) PACSSSSSSLFSAVV S170
ERF (rat) PACSSSSSSLFSAVV S170
S171-p
ACssSsssLFSAVVA
0 1
ERF (human) ACssSsssLFSAVVA S171-p
ERF iso2 (human) ACSSSSSSLFSAVVA S96
ERF (mouse) ACSSSSSSLFSAVVA S171
ERF (rat) ACSSSSSSLFSAVVA S171
R183-m1
VVARRLGrGsVsDCs
0 1
ERF (human) VVARRLGrGsVsDCs R183-m1
ERF iso2 (human) VVARRLGRGSVSDCS R108
ERF (mouse) VVARRLGRGsVsDCs R183
ERF (rat) VVARRLGRGSVSDCS R183
S185-p
ARRLGrGsVsDCsDG
Upstream
0 8
Treatment
  • selumetinib
  • vemurafenib
ERF (human) ARRLGrGsVsDCsDG S185-p
ERF iso2 (human) ARRLGRGSVSDCSDG S110
ERF (mouse) ARRLGRGsVsDCsDG S185-p
ERF (rat) ARRLGRGSVSDCSDG S185
S187-p
RLGrGsVsDCsDGTS
Upstream
0 4
Treatment
  • selumetinib
  • vemurafenib
ERF (human) RLGrGsVsDCsDGTS S187-p
ERF iso2 (human) RLGRGSVSDCSDGTS S112
ERF (mouse) RLGRGsVsDCsDGtS S187-p
ERF (rat) RLGRGSVSDCSDGTS S187
S190-p
rGsVsDCsDGTSELE
Upstream
0 5
Treatment
  • selumetinib
  • vemurafenib
ERF (human) rGsVsDCsDGTSELE S190-p
ERF iso2 (human) RGSVSDCSDGTSELE S115
ERF (mouse) RGsVsDCsDGtSELE S190-p
ERF (rat) RGSVSDCSDGTSELE S190
T193
VsDCsDGTSELEEPL
0 1
ERF (human) VsDCsDGTSELEEPL T193
ERF iso2 (human) VSDCSDGTSELEEPL T118
ERF (mouse) VsDCsDGtSELEEPL T193-p
ERF (rat) VSDCSDGTSELEEPL T193
R218-m1
PPDLGAFrGPPLArL
0 1
ERF (human) PPDLGAFrGPPLArL R218-m1
ERF iso2 (human) PPDLGAFRGPPLARL R143
ERF (mouse) PPELGAFRGPPLARL R218
ERF (rat) PPELGAFRGPPLARL R218
R224-m1
FrGPPLArLPHDPGV
0 3
ERF (human) FrGPPLArLPHDPGV R224-m1
ERF iso2 (human) FRGPPLARLPHDPGV R149
ERF (mouse) FRGPPLARLPHDPGV R224
ERF (rat) FRGPPLARLPHDPGV R224
R233-m1
PHDPGVFrVYPRPRG
0 1
ERF (human) PHDPGVFrVYPRPRG R233-m1
ERF iso2 (human) PHDPGVFRVYPRPRG R158
ERF (mouse) PHDPGVFRVYPRPRG R233
ERF (rat) PHDPGVFRVYPRPRG R233
S246-p
RGGPEPLsPFPVsPL
Upstream
Downstream
2 1
Effects on Modified Protein
  • intracellular localization
Effects on Biological Processes:
  • cell cycle regulation
Kinase, in vitro:
  • ERK2 (human)
Putative in vivo kinases:
  • ERK2 (human)
Treatment
  • EGF
  • PD98059
  • serum
ERF (human) RGGPEPLsPFPVsPL S246-p
ERF iso2 (human) RGGPEPLSPFPVSPL S171
ERF (mouse) RGGPEPLsPFPVsPL S246-p
ERF (rat) RGGPEPLSPFPVSPL S246
S251-p
PLsPFPVsPLAGPGS
Upstream
Downstream
2 3
Effects on Modified Protein
  • intracellular localization
Effects on Biological Processes:
  • cell cycle regulation
Kinase, in vitro:
  • ERK2 (human)
Putative in vivo kinases:
  • ERK2 (human)
Treatment
  • EGF
  • PD98059
  • serum
ERF (human) PLsPFPVsPLAGPGS S251-p
ERF iso2 (human) PLSPFPVSPLAGPGS S176
ERF (mouse) PLsPFPVsPLAGPGS S251-p
ERF (rat) PLSPFPVSPLAGPGS S251
S327-p
SVYNYHLsPrAFLHY
Upstream
0 19
Treatment
  • LRRK2-IN-1
ERF (human) SVYNYHLsPrAFLHY S327-p
ERF iso2 (human) SVYNYHLSPRAFLHY S252
ERF (mouse) SVYNYHLsPRAFLHY S327-p
ERF (rat) SVYNYHLSPRAFLHY S327
R329-m1
YNYHLsPrAFLHYPG
0 3
ERF (human) YNYHLsPrAFLHYPG R329-m1
ERF iso2 (human) YNYHLSPRAFLHYPG R254
ERF (mouse) YNYHLsPRAFLHYPG R329
ERF (rat) YNYHLSPRAFLHYPG R329
T357-p
LPPMAPEtPPVPSSA
Upstream
0 7
Treatment
  • ischemia
ERF (human) LPPMAPEtPPVPSSA T357-p
ERF iso2 (human) LPPMAPETPPVPSSA T282
ERF (mouse) LPPMAPEtPPVPSSA T357-p
ERF (rat) LPPMAPETPPVPSSA T357
S373
SSSSSSSSPFkFkLQ
0 1
ERF (human) SSSSSSSSPFkFkLQ S373
ERF iso2 (human) SSSSSSSSPFKFKLQ S298
ERF (mouse) SSSSSSSsPFKFKLQ S373-p
ERF (rat) SSSSSSSSPFKFKLQ S373
K376-m1
SSSSSPFkFkLQPPP
0 1
ERF (human) SSSSSPFkFkLQPPP K376-m1
ERF iso2 (human) SSSSSPFKFKLQPPP K301
ERF (mouse) SSSSsPFKFKLQPPP K376
ERF (rat) SSSSSPFKFKLQPPP K376
K378-sm
SSSPFkFkLQPPPLG
0 1
ERF (human) SSSPFkFkLQPPPLG K378-sm
ERF iso2 (human) SSSPFKFKLQPPPLG K303
ERF (mouse) SSsPFKFKLQPPPLG K378
ERF (rat) SSSPFKFKLQPPPLG K378
K394-ac
RQRAAGEkAVAGADK
0 1
ERF (human) RQRAAGEkAVAGADK K394-ac
ERF iso2 (human) RQRAAGEKAVAGADK K319
ERF (mouse) RQRAAGEKAPGGTDK K394
ERF (rat) RQRAAGEKAPGGTDK K394
S431-p
QIKVEPIsEGEsEEV
0 4
ERF (human) QIKVEPIsEGEsEEV S431-p
ERF iso2 (human) QIKVEPISEGESEEV S356
ERF (mouse) QIKVEPISEGESEEV S433
ERF (rat) QIKVEPISEGESEEV S434
S435-p
EPIsEGEsEEVEVtD
0 2
ERF (human) EPIsEGEsEEVEVtD S435-p
ERF iso2 (human) EPISEGESEEVEVTD S360
ERF (mouse) EPISEGESEEVEVTD S437
ERF (rat) EPISEGESEEVEVTD S438
T441-p
EsEEVEVtDIsDEDE
0 2
ERF (human) EsEEVEVtDIsDEDE T441-p
ERF iso2 (human) ESEEVEVTDISDEDE T366
ERF (mouse) ESEEVEVTDIsDEDE T443
ERF (rat) ESEEVEVTDISDEDE T444
S444-p
EVEVtDIsDEDEEDG
0 6
ERF (human) EVEVtDIsDEDEEDG S444-p
ERF iso2 (human) EVEVTDISDEDEEDG S369
ERF (mouse) EVEVTDIsDEDEEDG S446-p
ERF (rat) EVEVTDISDEDEEDG S447
T456-p
EDGEVFKtPRAPPAP
0 1
ERF (human) EDGEVFKtPRAPPAP T456-p
ERF iso2 (human) EDGEVFKTPRAPPAP T381
ERF (mouse) EDGEVFKTPRAPPAP T458
ERF (rat) EDGEVFKTPRAPPAP T459
K465-sm
RAPPAPPkPEPGEAP
0 1
ERF (human) RAPPAPPkPEPGEAP K465-sm
ERF iso2 (human) RAPPAPPKPEPGEAP K390
ERF (mouse) RAPPAPPKPEPGEAP K467
ERF (rat) RAPPAPPKPEPGEAP K468
S489-p
LRFKRRWsEDCRLEG
0 8
ERF (human) LRFKRRWsEDCRLEG S489-p
ERF iso2 (human) LRFKRRWSEDCRLEG S414
ERF (mouse) LRFKRRWsEDCRLEG S491-p
ERF (rat) LRFKRRWSEDCRLEG S492
K512-sm
EDEGEDKkVRGEGPG
0 1
ERF (human) EDEGEDKkVRGEGPG K512-sm
ERF iso2 (human) EDEGEDKKVRGEGPG K437
ERF (mouse) EDEGEDKKVRGDVGP K514
ERF (rat) EDEGEDKKVRGDMGP K515
A521
RGEGPGEAGGPLtPR
0 1
ERF (human) RGEGPGEAGGPLtPR A521
ERF iso2 (human) RGEGPGEAGGPLTPR A446
ERF (mouse) GDVGPGEsGGPLtPR S524-p
ERF (rat) GDMGPGEPGGPLTPR P525
T526-p
GEAGGPLtPRRVssD
Upstream
Downstream
3 164
Effects on Modified Protein
  • intracellular localization
Effects on Biological Processes:
  • cell cycle regulation
  • transcription, induced
Kinase, in vitro:
  • ERK2 (human)
Phosphatases, in vitro:
  • PPP1CA (human)
  • PPP2CA (human)
Putative in vivo kinases:
  • ERK2 (human)
Treatment
  • antibody
  • CXCL12
  • EGF
  • ionomycin
  • ischemia
  • OAG
  • okadaic_acid
  • PD98059
  • phorbol_ester
  • selumetinib
  • serum
  • vemurafenib
ERF (human) GEAGGPLtPRRVssD T526-p
ERF iso2 (human) GEAGGPLTPRRVSSD T451
ERF (mouse) GEsGGPLtPRRVssD T529-p
ERF (rat) GEPGGPLTPRRVSSD T530
S531-p
PLtPRRVssDLQHAT
Upstream
0 16
Treatment
  • BI2536
ERF (human) PLtPRRVssDLQHAT S531-p
ERF iso2 (human) PLTPRRVSSDLQHAT S456
ERF (mouse) PLtPRRVssDLQHAT S534-p
ERF (rat) PLTPRRVSSDLQHAT S535
S532-p
LtPRRVssDLQHATA
Upstream
0 5
Treatment
  • metastatic potential
ERF (human) LtPRRVssDLQHATA S532-p
ERF iso2 (human) LTPRRVSSDLQHATA S457
ERF (mouse) LtPRRVssDLQHATA S535-p
ERF (rat) LTPRRVSSDLQHATA S536
S542-p
QHATAQLsLEHRDs_
0 4
ERF (human) QHATAQLsLEHRDs_ S542-p
ERF iso2 (human) QHATAQLSLEHRDS_ S467
ERF (mouse) QHATAQLsLEHRDs_ S545-p
ERF (rat) QHATAQLSLEHRDS_ S546
S548-p
LsLEHRDs_______
Upstream
0 6
Treatment
  • BI2536
ERF (human) LsLEHRDs_______ S548-p
ERF iso2 (human) LSLEHRDS_______ S473
ERF (mouse) LsLEHRDs_______ S551-p
ERF (rat) LSLEHRDS_______ S552