Other Species / Isoforms
  IDH2 (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

  HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
K45
HYADKRIKVAkPVVE
0 3
IDH2 (human) HYADKRIKVAkPVVE K45
IDH2 (mouse) HYAEKRIkVEkPVVE K45-ac
IDH2 (rat) HYAEKRIkVEkPVVE K45-ac
K48-ac
DKRIKVAkPVVEMDG
0 4
IDH2 (human) DKRIKVAkPVVEMDG K48-ac
IDH2 (mouse) EKRIkVEkPVVEMDG K48-ac
IDH2 (rat) EKRIkVEkPVVEMDG K48-ac
K48
DKRIKVAKPVVEMDG
0 1
IDH2 (human) DKRIKVAKPVVEMDG K48
IDH2 (mouse) EKRIkVEkPVVEMDG K48-ub
IDH2 (rat) EKRIkVEKPVVEMDG K48
K67-ac
RIIWQFIkEkLILPH
0 3
IDH2 (human) RIIWQFIkEkLILPH K67-ac
IDH2 (mouse) RIIWQFIkEkLILPH K67-ac
IDH2 (rat) RIIWQFIkEkLILPH K67-ac
K67
RIIWQFIKEkLILPH
0 1
IDH2 (human) RIIWQFIKEkLILPH K67
IDH2 (mouse) RIIWQFIkEkLILPH K67-ub
IDH2 (rat) RIIWQFIKEkLILPH K67
K69-ac
IWQFIkEkLILPHVD
0 6
IDH2 (human) IWQFIkEkLILPHVD K69-ac
IDH2 (mouse) IWQFIkEkLILPHVD K69-ac
IDH2 (rat) IWQFIkEkLILPHVD K69-ac
K69-ub
IWQFIkEkLILPHVD
0 1
IDH2 (human) IWQFIkEkLILPHVD K69-ub
IDH2 (mouse) IWQFIkEKLILPHVD K69
IDH2 (rat) IWQFIkEKLILPHVD K69
K80-ac
PHVDIQLkYFDLGLP
1 75
IDH2 (human) PHVDIQLkYFDLGLP K80-ac
IDH2 (mouse) PHVDVQLkYFDLGLP K80-ac
IDH2 (rat) PHVDVQLkYFDLGLP K80-ac
K80
PHVDIQLKYFDLGLP
0 1
IDH2 (human) PHVDIQLKYFDLGLP K80
IDH2 (mouse) PHVDVQLkYFDLGLP K80-sc
IDH2 (rat) PHVDVQLKYFDLGLP K80
K80-ub
PHVDIQLkYFDLGLP
0 1
IDH2 (human) PHVDIQLkYFDLGLP K80-ub
IDH2 (mouse) PHVDVQLKYFDLGLP K80
IDH2 (rat) PHVDVQLKYFDLGLP K80
T97-p
DQTDDQVtIDsALAT
0 2
IDH2 (human) DQTDDQVtIDsALAT T97-p
IDH2 (mouse) DQTNDQVTIDSALAT T97
IDH2 (rat) DQTNDQVTIDSALAT T97
S100-p
DDQVtIDsALATQky
0 2
IDH2 (human) DDQVtIDsALATQky S100-p
IDH2 (mouse) NDQVTIDSALATQkY S100
IDH2 (rat) NDQVTIDSALATQkY S100
K106-ac
DsALATQkysVAVkC
Downstream
2 47
Effects on Modified Protein
  • enzymatic activity, inhibited
IDH2 (human) DsALATQkysVAVkC K106-ac
IDH2 (mouse) DSALATQkYSVAVKC K106-ac
IDH2 (rat) DSALATQkYSVAVKC K106-ac
K106-ub
DsALATQkysVAVkC
0 2
IDH2 (human) DsALATQkysVAVkC K106-ub
IDH2 (mouse) DSALATQkYSVAVKC K106-ub
IDH2 (rat) DSALATQKYSVAVKC K106
K106
DsALATQKysVAVkC
0 2
IDH2 (human) DsALATQKysVAVkC K106
IDH2 (mouse) DSALATQkYSVAVKC K106-sc
IDH2 (rat) DSALATQKYSVAVKC K106
Y107-p
sALATQkysVAVkCA
Upstream
Downstream
1 6
Effects on Modified Protein
  • intracellular localization
Kinase, in vitro:
  • FLT3 (human)
IDH2 (human) sALATQkysVAVkCA Y107-p
IDH2 (mouse) SALATQkYSVAVKCA Y107
IDH2 (rat) SALATQkYSVAVKCA Y107
S108-p
ALATQkysVAVkCAt
0 5
IDH2 (human) ALATQkysVAVkCAt S108-p
IDH2 (mouse) ALATQkYSVAVKCAT S108
IDH2 (rat) ALATQkYSVAVKCAT S108
K112-ub
QkysVAVkCAtItPD
0 2
IDH2 (human) QkysVAVkCAtItPD K112-ub
IDH2 (mouse) QkYSVAVKCATITPD K112
IDH2 (rat) QkYSVAVKCATITPD K112
T115-p
sVAVkCAtItPDEAR
0 1
IDH2 (human) sVAVkCAtItPDEAR T115-p
IDH2 (mouse) SVAVKCATITPDEAR T115
IDH2 (rat) SVAVKCATITPDEAR T115
T117-p
AVkCAtItPDEARVE
0 1
IDH2 (human) AVkCAtItPDEARVE T117-p
IDH2 (mouse) AVKCATITPDEARVE T117
IDH2 (rat) AVKCATITPDEARVE T117
K127-ub
EARVEEFkLKKMWks
0 4
IDH2 (human) EARVEEFkLKKMWks K127-ub
IDH2 (mouse) EARVEEFkLKKMWks K127-ub
IDH2 (rat) EARVEEFKLkKMWkS K127
K127-ac
EARVEEFkLKKMWks
0 2
IDH2 (human) EARVEEFkLKKMWks K127-ac
IDH2 (mouse) EARVEEFKLKKMWks K127
IDH2 (rat) EARVEEFkLkKMWkS K127-ac
K129
RVEEFkLKKMWksPN
0 1
IDH2 (human) RVEEFkLKKMWksPN K129
IDH2 (mouse) RVEEFkLKKMWksPN K129
IDH2 (rat) RVEEFkLkKMWkSPN K129-ac
K133-ac
FkLKKMWksPNGTIR
Upstream
0 10
Treatment
  • MS275
IDH2 (human) FkLKKMWksPNGTIR K133-ac
IDH2 (mouse) FkLKKMWksPNGTIR K133-ac
IDH2 (rat) FkLkKMWkSPNGTIR K133-ac
S134-p
kLKKMWksPNGTIRN
0 5
IDH2 (human) kLKKMWksPNGTIRN S134-p
IDH2 (mouse) kLKKMWksPNGTIRN S134-p
IDH2 (rat) kLkKMWkSPNGTIRN S134
K155-ac
FREPIICkNIPRLVP
1 9
IDH2 (human) FREPIICkNIPRLVP K155-ac
IDH2 (mouse) FREPIICkNIPRLVP K155-ac
IDH2 (rat) FREPIICkNIPRLVP K155-ac
K155-ub
FREPIICkNIPRLVP
0 1
IDH2 (human) FREPIICkNIPRLVP K155-ub
IDH2 (mouse) FREPIICKNIPRLVP K155
IDH2 (rat) FREPIICKNIPRLVP K155
K166-ac
RLVPGWTkPITIGRH
Downstream
2 20
Effects on Modified Protein
  • enzymatic activity, inhibited
IDH2 (human) RLVPGWTkPITIGRH K166-ac
IDH2 (mouse) RLVPGWTkPITIGRH K166-ac
IDH2 (rat) RLVPGWTkPITIGRH K166-ac
K166-ub
RLVPGWTkPITIGRH
0 5
IDH2 (human) RLVPGWTkPITIGRH K166-ub
IDH2 (mouse) RLVPGWTkPITIGRH K166-ub
IDH2 (rat) RLVPGWTKPITIGRH K166
K166
RLVPGWTKPITIGRH
0 2
IDH2 (human) RLVPGWTKPITIGRH K166
IDH2 (mouse) RLVPGWTkPITIGRH K166-sc
IDH2 (rat) RLVPGWTKPITIGRH K166
Y179-p
RHAHGDQykAtDFVA
0 11
IDH2 (human) RHAHGDQykAtDFVA Y179-p
IDH2 (mouse) RHAHGDQYkATDFVV Y179
IDH2 (rat) RHAHGDQykATDFVV Y179-p
K180-ac
HAHGDQykAtDFVAD
Upstream
1 49
Treatment
  • vorinostat
IDH2 (human) HAHGDQykAtDFVAD K180-ac
IDH2 (mouse) HAHGDQYkATDFVVD K180-ac
IDH2 (rat) HAHGDQykATDFVVD K180-ac
K180-ub
HAHGDQykAtDFVAD
0 2
IDH2 (human) HAHGDQykAtDFVAD K180-ub
IDH2 (mouse) HAHGDQYkATDFVVD K180-ub
IDH2 (rat) HAHGDQyKATDFVVD K180
K180-sc
HAHGDQykAtDFVAD
0 2
IDH2 (human) HAHGDQykAtDFVAD K180-sc
IDH2 (mouse) HAHGDQYkATDFVVD K180-sc
IDH2 (rat) HAHGDQyKATDFVVD K180
T182-p
HGDQykAtDFVADrA
0 1
IDH2 (human) HGDQykAtDFVADrA T182-p
IDH2 (mouse) HGDQYkATDFVVDRA T182
IDH2 (rat) HGDQykATDFVVDRA T182
R188-m1
AtDFVADrAGtFkMV
0 1
IDH2 (human) AtDFVADrAGtFkMV R188-m1
IDH2 (mouse) ATDFVVDRAGTFkLV R188
IDH2 (rat) ATDFVVDRAGMFkLV R188
T191-p
FVADrAGtFkMVFtP
0 1
IDH2 (human) FVADrAGtFkMVFtP T191-p
IDH2 (mouse) FVVDRAGTFkLVFTP T191
IDH2 (rat) FVVDRAGMFkLVFTP M191
K193-ac
ADrAGtFkMVFtPkD
0 5
IDH2 (human) ADrAGtFkMVFtPkD K193-ac
IDH2 (mouse) VDRAGTFkLVFTPkD K193-ac
IDH2 (rat) VDRAGMFkLVFTPkD K193-ac
K193-ub
ADrAGtFkMVFtPkD
0 2
IDH2 (human) ADrAGtFkMVFtPkD K193-ub
IDH2 (mouse) VDRAGTFKLVFTPkD K193
IDH2 (rat) VDRAGMFKLVFTPkD K193
T197-p
GtFkMVFtPkDGSGV
0 1
IDH2 (human) GtFkMVFtPkDGSGV T197-p
IDH2 (mouse) GTFkLVFTPkDGSSA T197
IDH2 (rat) GMFkLVFTPkDGSGA T197
K199
FkMVFtPKDGSGVKE
0 5
IDH2 (human) FkMVFtPKDGSGVKE K199
IDH2 (mouse) FkLVFTPkDGSSAKE K199-ac
IDH2 (rat) FkLVFTPkDGSGAKE K199-ac
K199-ub
FkMVFtPkDGSGVKE
0 2
IDH2 (human) FkMVFtPkDGSGVKE K199-ub
IDH2 (mouse) FkLVFTPkDGSSAKE K199-ub
IDH2 (rat) FkLVFTPKDGSGAKE K199
K199-sc
FkMVFtPkDGSGVKE
0 2
IDH2 (human) FkMVFtPkDGSGVKE K199-sc
IDH2 (mouse) FkLVFTPkDGSSAKE K199-sc
IDH2 (rat) FkLVFTPKDGSGAKE K199
K242-ac
CFQYAIQkkWPLyMS
0 1
IDH2 (human) CFQYAIQkkWPLyMS K242-ac
IDH2 (mouse) CFQYSIQKkWPLYLS K242
IDH2 (rat) CFQYSIQKkWPLYLS K242
K243
FQYAIQkKWPLyMST
0 1
IDH2 (human) FQYAIQkKWPLyMST K243
IDH2 (mouse) FQYSIQKkWPLYLST K243-sc
IDH2 (rat) FQYSIQKKWPLYLST K243
K243-ac
FQYAIQkkWPLyMST
1 3
IDH2 (human) FQYAIQkkWPLyMST K243-ac
IDH2 (mouse) FQYSIQKkWPLYLST K243-ac
IDH2 (rat) FQYSIQKkWPLYLST K243-ac
Y247-p
IQkkWPLyMSTKNTI
0 1
IDH2 (human) IQkkWPLyMSTKNTI Y247-p
IDH2 (mouse) IQKkWPLYLSTkNTI Y247
IDH2 (rat) IQKkWPLYLSTkNTI Y247
K251
WPLyMSTKNTILkAY
1 1
IDH2 (human) WPLyMSTKNTILkAY K251
IDH2 (mouse) WPLYLSTkNTILkAY K251-ac
IDH2 (rat) WPLYLSTkNTIMkAY K251-ac
K256-ac
STKNTILkAYDGRFk
1 4
IDH2 (human) STKNTILkAYDGRFk K256-ac
IDH2 (mouse) STkNTILkAYDGRFk K256-ac
IDH2 (rat) STkNTIMkAYDGRFk K256-ac
K256-ub
STKNTILkAYDGRFk
0 3
IDH2 (human) STKNTILkAYDGRFk K256-ub
IDH2 (mouse) STkNTILkAYDGRFk K256-ub
IDH2 (rat) STkNTIMKAYDGRFk K256
K256-sc
STKNTILkAYDGRFk
0 2
IDH2 (human) STKNTILkAYDGRFk K256-sc
IDH2 (mouse) STkNTILkAYDGRFk K256-sc
IDH2 (rat) STkNTIMKAYDGRFk K256
K263-ac
kAYDGRFkDIFQEIF
1 23
IDH2 (human) kAYDGRFkDIFQEIF K263-ac
IDH2 (mouse) kAYDGRFkDIFQEIF K263-ac
IDH2 (rat) kAYDGRFkDIFQEIF K263-ac
K263-ub
kAYDGRFkDIFQEIF
0 3
IDH2 (human) kAYDGRFkDIFQEIF K263-ub
IDH2 (mouse) kAYDGRFkDIFQEIF K263-ub
IDH2 (rat) kAYDGRFKDIFQEIF K263
K272-ac
IFQEIFDkHYkTDFD
Upstream
1 13
Treatment
  • vorinostat
IDH2 (human) IFQEIFDkHYkTDFD K272-ac
IDH2 (mouse) IFQEIFDkHYkTDFD K272-ac
IDH2 (rat) IFQEIFDkHYkTDFD K272-ac
K272-ub
IFQEIFDkHYkTDFD
0 3
IDH2 (human) IFQEIFDkHYkTDFD K272-ub
IDH2 (mouse) IFQEIFDkHYkTDFD K272-ub
IDH2 (rat) IFQEIFDKHYkTDFD K272
K275-ac
EIFDkHYkTDFDkNk
Upstream
1 3
Treatment
  • vorinostat
IDH2 (human) EIFDkHYkTDFDkNk K275-ac
IDH2 (mouse) EIFDkHYkTDFDkNk K275-ac
IDH2 (rat) EIFDkHYkTDFDkNk K275-ac
K275-sc
EIFDkHYkTDFDkNk
0 1
IDH2 (human) EIFDkHYkTDFDkNk K275-sc
IDH2 (mouse) EIFDkHYkTDFDkNk K275-sc
IDH2 (rat) EIFDkHYKTDFDkNk K275
K275-ub
EIFDkHYkTDFDkNk
0 1
IDH2 (human) EIFDkHYkTDFDkNk K275-ub
IDH2 (mouse) EIFDkHYKTDFDkNk K275
IDH2 (rat) EIFDkHYKTDFDkNk K275
K280-ac
HYkTDFDkNkIWYEH
1 3
IDH2 (human) HYkTDFDkNkIWYEH K280-ac
IDH2 (mouse) HYkTDFDkNkIWYEH K280-ac
IDH2 (rat) HYkTDFDkNkIWYEH K280-ac
K280
HYkTDFDKNkIWYEH
0 2
IDH2 (human) HYkTDFDKNkIWYEH K280
IDH2 (mouse) HYkTDFDkNkIWYEH K280-sc
IDH2 (rat) HYkTDFDKNkIWYEH K280
K282-ac
kTDFDkNkIWYEHRL
1 6
IDH2 (human) kTDFDkNkIWYEHRL K282-ac
IDH2 (mouse) kTDFDkNkIWYEHRL K282-ac
IDH2 (rat) kTDFDkNkIWYEHRL K282-ac
K282
kTDFDkNKIWYEHRL
0 1
IDH2 (human) kTDFDkNKIWYEHRL K282
IDH2 (mouse) kTDFDkNkIWYEHRL K282-sc
IDH2 (rat) kTDFDkNKIWYEHRL K282
K282
kTDFDkNKIWYEHRL
0 1
IDH2 (human) kTDFDkNKIWYEHRL K282
IDH2 (mouse) kTDFDkNkIWYEHRL K282-sm
IDH2 (rat) kTDFDkNKIWYEHRL K282
K282-ub
kTDFDkNkIWYEHRL
0 1
IDH2 (human) kTDFDkNkIWYEHRL K282-ub
IDH2 (mouse) kTDFDkNKIWYEHRL K282
IDH2 (rat) kTDFDkNKIWYEHRL K282
S301-p
VAQVLKSsGGFVWAC
0 1
IDH2 (human) VAQVLKSsGGFVWAC S301-p
IDH2 (mouse) VAQVLKSSGGFVWAC S301
IDH2 (rat) VAQVLKSSGGFVWAC S301
T350-p
EAEAAHGtVTrHYRE
0 1
IDH2 (human) EAEAAHGtVTrHYRE T350-p
IDH2 (mouse) EAEAAHGTVTrHYRE T350
IDH2 (rat) EAEAAHGTVTRHYRE T350
R353-m2
AAHGtVTrHYREHQK
Downstream
1 0
Effects on Modified Protein
  • enzymatic activity, induced
Effects on Biological Processes:
  • cell growth, induced
IDH2 (human) AAHGtVTrHYREHQK R353-m2
IDH2 (mouse) AAHGTVTrHYREHQk R353-m2
IDH2 (rat) AAHGTVTRHYREHQK R353
K360
rHYREHQKGRPTSTN
1 1
IDH2 (human) rHYREHQKGRPTSTN K360
IDH2 (mouse) rHYREHQkGRPTSTN K360-ac
IDH2 (rat) RHYREHQKGRPTSTN K360
K360
rHYREHQKGRPTSTN
0 1
IDH2 (human) rHYREHQKGRPTSTN K360
IDH2 (mouse) rHYREHQkGRPTSTN K360-sc
IDH2 (rat) RHYREHQKGRPTSTN K360
K384-ac
RGLEHRGkLDGNQDL
Downstream
2 18
Effects on Modified Protein
  • enzymatic activity, inhibited
IDH2 (human) RGLEHRGkLDGNQDL K384-ac
IDH2 (mouse) RGLEHRGkLDGnQDL K384-ac
IDH2 (rat) RGLEHRGkLDGNQDL K384-ac
K384-ub
RGLEHRGkLDGNQDL
0 3
IDH2 (human) RGLEHRGkLDGNQDL K384-ub
IDH2 (mouse) RGLEHRGkLDGnQDL K384-ub
IDH2 (rat) RGLEHRGKLDGNQDL K384
K384
RGLEHRGKLDGNQDL
0 1
IDH2 (human) RGLEHRGKLDGNQDL K384
IDH2 (mouse) RGLEHRGkLDGnQDL K384-sc
IDH2 (rat) RGLEHRGKLDGNQDL K384
N388
HRGkLDGNQDLIRFA
0 1
IDH2 (human) HRGkLDGNQDLIRFA N388
IDH2 (mouse) HRGkLDGnQDLIRFA N388-ng
IDH2 (rat) HRGkLDGNQDLIRFA N388
K400
RFAQMLEKVCVETVE
0 4
IDH2 (human) RFAQMLEKVCVETVE K400
IDH2 (mouse) RFAQTLEkVCVQTVE K400-ac
IDH2 (rat) RFAQTLEkVCVQTVE K400-ac
K400
RFAQMLEKVCVETVE
0 1
IDH2 (human) RFAQMLEKVCVETVE K400
IDH2 (mouse) RFAQTLEkVCVQTVE K400-sc
IDH2 (rat) RFAQTLEKVCVQTVE K400
K400-ub
RFAQMLEkVCVETVE
0 1
IDH2 (human) RFAQMLEkVCVETVE K400-ub
IDH2 (mouse) RFAQTLEKVCVQTVE K400
IDH2 (rat) RFAQTLEKVCVQTVE K400
K413-ac
VESGAMTkDLAGCIH
Upstream
Downstream
6 8
Effects on Modified Protein
  • enzymatic activity, inhibited
  • molecular association, regulation
Effects on Biological Processes:
  • carcinogenesis, induced
  • cell growth, induced
Treatment
  • quizartinib
  • siRNA
IDH2 (human) VESGAMTkDLAGCIH K413-ac
IDH2 (mouse) VESGAMTkDLAGCIH K413-ac
IDH2 (rat) VESGAMTkDLAGCIH K413-ac
K413-ub
VESGAMTkDLAGCIH
0 2
IDH2 (human) VESGAMTkDLAGCIH K413-ub
IDH2 (mouse) VESGAMTKDLAGCIH K413
IDH2 (rat) VESGAMTKDLAGCIH K413
S423-p
AGCIHGLsNVkLNEH
0 12
IDH2 (human) AGCIHGLsNVkLNEH S423-p
IDH2 (mouse) AGCIHGLsNVKLNEH S423-p
IDH2 (rat) AGCIHGLSNVKLNEH S423
K426-ub
IHGLsNVkLNEHFLN
0 1
IDH2 (human) IHGLsNVkLNEHFLN K426-ub
IDH2 (mouse) IHGLsNVKLNEHFLN K426
IDH2 (rat) IHGLSNVKLNEHFLN K426
K442-ac
TDFLDTIkSNLDRAL
1 8
IDH2 (human) TDFLDTIkSNLDRAL K442-ac
IDH2 (mouse) TDFLDTIkSNLDRAL K442-ac
IDH2 (rat) TDFLDTIkSNLDRAL K442-ac
K442-ub
TDFLDTIkSNLDRAL
0 1
IDH2 (human) TDFLDTIkSNLDRAL K442-ub
IDH2 (mouse) TDFLDTIKSNLDRAL K442
IDH2 (rat) TDFLDTIKSNLDRAL K442
R451
NLDRALGRQ______
0 1
IDH2 (human) NLDRALGRQ______ R451
IDH2 (mouse) NLDRALGkQ______ K451-ac
IDH2 (rat) NLDRALGKQ______ K451