Other Species / Isoforms
  GJA1 (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

 HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
S5
___MGDWSALGkLLD
0 3
GJA1 (human) ___MGDWSALGkLLD S5
GJA1 (mouse) ___MGDWsALGkLLD S5-p
GJA1 (rat) ___MGDWsALGKLLD S5-p
GJA1 (rabbit) ___MGDWSALGKLLD S5
GJA1 (pig) ___MGDWSALGKLLD S5
GJA1 (hamster) ___MGDWSALGKLLD S5
GJA1 (cow) ___MGDWSALGKLLD S5
K9-ub
GDWSALGkLLDKVQA
0 2
GJA1 (human) GDWSALGkLLDKVQA K9-ub
GJA1 (mouse) GDWsALGkLLDKVQA K9-ub
GJA1 (rat) GDWsALGKLLDKVQA K9
GJA1 (rabbit) GDWSALGKLLDKVQA K9
GJA1 (pig) GDWSALGKLLDKVQA K9
GJA1 (hamster) GDWSALGKLLDKVQA K9
GJA1 (cow) GDWSALGKLLDKVQA K9
K108
RKEEKLNKkEEELKV
0 1
GJA1 (human) RKEEKLNKkEEELKV K108
GJA1 (mouse) RKEEKLNkkEEELKV K108-ub
GJA1 (rat) RKEEKLNKkEEELKV K108
GJA1 (rabbit) RKEEKLNKKEEELKV K108
GJA1 (pig) RKEEKLNKKEEELKV K108
GJA1 (hamster) RKEEKLNKKEEELKV K108
GJA1 (cow) RKEEKLNKKEEELKV K108
K109-ub
KEEKLNKkEEELKVA
0 17
GJA1 (human) KEEKLNKkEEELKVA K109-ub
GJA1 (mouse) KEEKLNkkEEELKVA K109-ub
GJA1 (rat) KEEKLNKkEEELKVA K109-ub
GJA1 (rabbit) KEEKLNKKEEELKVA K109
GJA1 (pig) KEEKLNKKEEELKVA K109
GJA1 (hamster) KEEKLNKKEEELKVA K109
GJA1 (cow) KEEKLNKKEEELKVV K109
K128-ub
VNVDMHLkQIEIKKF
Upstream
0 10
Treatment
  • vorinostat
GJA1 (human) VNVDMHLkQIEIKKF K128-ub
GJA1 (mouse) VNVEMHLkQIEIkKF K128-ub
GJA1 (rat) VNVEMHLkQIEIkkF K128-ub
GJA1 (rabbit) VNVEMHLKQIEIKKF K128
GJA1 (pig) VNVEMHLKQIEIKKF K128
GJA1 (hamster) ANVDMHLKQIEIKKF K128
GJA1 (cow) ANVDMHLKQIEIKKF K129
K133
HLkQIEIKKFkyGIE
0 1
GJA1 (human) HLkQIEIKKFkyGIE K133
GJA1 (mouse) HLkQIEIkKFkyGIE K133-ub
GJA1 (rat) HLkQIEIKkFkyGIE K133
GJA1 (rabbit) HLKQIEIKKFKYGIE K133
GJA1 (pig) HLKQIEIKKFKYGIE K133
GJA1 (hamster) HLKQIEIKKFKYGIE K133
GJA1 (cow) HLKQIEIKKFKYGIE K134
K133
HLkQIEIKKFkyGIE
0 1
GJA1 (human) HLkQIEIKKFkyGIE K133
GJA1 (mouse) HLkQIEIKKFkyGIE K133
GJA1 (rat) HLkQIEIkkFkyGIE K133-ac
GJA1 (rabbit) HLKQIEIKKFKYGIE K133
GJA1 (pig) HLKQIEIKKFKYGIE K133
GJA1 (hamster) HLKQIEIKKFKYGIE K133
GJA1 (cow) HLKQIEIKKFKYGIE K134
K134
LkQIEIKKFkyGIEE
0 1
GJA1 (human) LkQIEIKKFkyGIEE K134
GJA1 (mouse) LkQIEIkKFkyGIEE K134
GJA1 (rat) LkQIEIkkFkyGIEE K134-ub
GJA1 (rabbit) LKQIEIKKFKYGIEE K134
GJA1 (pig) LKQIEIKKFKYGIEE K134
GJA1 (hamster) LKQIEIKKFKYGIEE K134
GJA1 (cow) LKQIEIKKFKYGIEE K135
K136-ub
QIEIKKFkyGIEEHG
0 5
GJA1 (human) QIEIKKFkyGIEEHG K136-ub
GJA1 (mouse) QIEIkKFkyGIEEHG K136-ub
GJA1 (rat) QIEIkkFkyGIEEHG K136-ub
GJA1 (rabbit) QIEIKKFKYGIEEHG K136
GJA1 (pig) QIEIKKFKYGIEEHG K136
GJA1 (hamster) QIEIKKFKYGIEEHG K136
GJA1 (cow) QIEIKKFKYGIEEHG K137
Y137-p
IEIKKFkyGIEEHGk
0 22
GJA1 (human) IEIKKFkyGIEEHGk Y137-p
GJA1 (mouse) IEIkKFkyGIEEHGk Y137-p
GJA1 (rat) IEIkkFkyGIEEHGK Y137-p
GJA1 (rabbit) IEIKKFKYGIEEHGK Y137
GJA1 (pig) IEIKKFKYGIEEHGK Y137
GJA1 (hamster) IEIKKFKYGIEEHGK Y137
GJA1 (cow) IEIKKFKYGIEEHGK Y138
K144-ub
yGIEEHGkVKMRGGL
0 2
GJA1 (human) yGIEEHGkVKMRGGL K144-ub
GJA1 (mouse) yGIEEHGkVKMRGGL K144-ub
GJA1 (rat) yGIEEHGKVKMRGGL K144
GJA1 (rabbit) YGIEEHGKVKMRGGL K144
GJA1 (pig) YGIEEHGKVKMRGGL K144
GJA1 (hamster) YGIEEHGKVKMRGGL K144
GJA1 (cow) YGIEEHGKVKMRGGL K145
K243-ub
VKDRVKGksDPyHAt
0 4
GJA1 (human) VKDRVKGksDPyHAt K243-ub
GJA1 (mouse) VKDRVKGRSDPyHAt R243
GJA1 (rat) VKDRVKGRsDPyHAT R243
GJA1 (rabbit) VKDRVKGKSDPYHAT K243
GJA1 (pig) VKDRVKGKSDPYHAT K243
GJA1 (hamster) VKDRVKGRSDPYHAT R243
GJA1 (cow) VKDRVKGKSDPYHTT K244
S244-p
KDRVKGksDPyHAts
0 8
GJA1 (human) KDRVKGksDPyHAts S244-p
GJA1 (mouse) KDRVKGRSDPyHAtT S244
GJA1 (rat) KDRVKGRsDPyHATT S244-p
GJA1 (rabbit) KDRVKGKSDPYHATT S244
GJA1 (pig) KDRVKGKSDPYHATT S244
GJA1 (hamster) KDRVKGRSDPYHATT S244
GJA1 (cow) KDRVKGKSDPYHTTT S245
Y247-p
VKGksDPyHAtsGAL
Upstream
Downstream
12 254
Effects on Modified Protein
  • intracellular localization
  • protein conformation
Kinase, in vitro:
  • Src (human)
Putative in vivo kinases:
  • Src (human)
GJA1 (human) VKGksDPyHAtsGAL Y247-p
GJA1 (mouse) VKGRSDPyHAtTGPL Y247-p
GJA1 (rat) VKGRsDPyHATTGPL Y247-p
GJA1 (rabbit) VKGKSDPYHATTGPL Y247
GJA1 (pig) VKGKSDPYHATTGPL Y247
GJA1 (hamster) VKGRSDPYHATTGPL Y247
GJA1 (cow) VKGKSDPYHTTTGPL Y248
T250-p
ksDPyHAtsGALsPA
0 6
GJA1 (human) ksDPyHAtsGALsPA T250-p
GJA1 (mouse) RSDPyHAtTGPLsPs T250-p
GJA1 (rat) RsDPyHATTGPLsPs T250
GJA1 (rabbit) KSDPYHATTGPLSPS T250
GJA1 (pig) KSDPYHATTGPLsPS T250
GJA1 (hamster) RSDPYHATTGPLNPS T250
GJA1 (cow) KSDPYHTTTGPLSPS T251
S251-p
sDPyHAtsGALsPAk
0 5
GJA1 (human) sDPyHAtsGALsPAk S251-p
GJA1 (mouse) SDPyHAtTGPLsPsk T251
GJA1 (rat) sDPyHATTGPLsPsk T251
GJA1 (rabbit) SDPYHATTGPLSPSK T251
GJA1 (pig) SDPYHATTGPLsPSK T251
GJA1 (hamster) SDPYHATTGPLNPSK T251
GJA1 (cow) SDPYHTTTGPLSPSK T252
S255-p
HAtsGALsPAkDCGs
Upstream
Downstream
19 20
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
  • protein conformation
Effects on Biological Processes:
  • endocytosis, induced
Kinase, in vitro:
  • CDK1 (human)
  • MAPKAPK2 (human)
Regulatory protein:
  • HSP70 (human)
Treatment
  • cAMP_analog
  • colforsin
  • EGF
  • levonorgestrel/norgestrel
  • phorbol_ester
GJA1 (human) HAtsGALsPAkDCGs S255-p
GJA1 (mouse) HAtTGPLsPskDCGs S255-p
GJA1 (rat) HATTGPLsPskDCGs S255-p
GJA1 (rabbit) HATTGPLSPSKDCGS S255
GJA1 (pig) HATTGPLsPSKDCGs S255-p
GJA1 (hamster) HATTGPLNPSKDCGS N255
GJA1 (cow) HTTTGPLSPSKDCGS S256
A257
tsGALsPAkDCGsQk
1 8
GJA1 (human) tsGALsPAkDCGsQk A257
GJA1 (mouse) tTGPLsPskDCGsPk S257-p
GJA1 (rat) TTGPLsPskDCGsPk S257-p
GJA1 (rabbit) TTGPLSPSKDCGSPK S257
GJA1 (pig) TTGPLsPSKDCGsPK S257
GJA1 (hamster) TTGPLNPSKDCGSPK S257
GJA1 (cow) TTGPLSPSKDCGSPK S258
K258-ub
sGALsPAkDCGsQky
0 38
GJA1 (human) sGALsPAkDCGsQky K258-ub
GJA1 (mouse) TGPLsPskDCGsPky K258-ub
GJA1 (rat) TGPLsPskDCGsPky K258-ub
GJA1 (rabbit) TGPLSPSKDCGSPKY K258
GJA1 (pig) TGPLsPSKDCGsPKY K258
GJA1 (hamster) TGPLNPSKDCGSPKY K258
GJA1 (cow) TGPLSPSKDCGSPKY K259
S262-p
sPAkDCGsQkyAyFN
Upstream
Downstream
27 9
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
  • protein conformation
Effects on Biological Processes:
  • apoptosis, inhibited
  • cell growth, altered
  • endocytosis, induced
Kinase, in vitro:
  • CDK1 (human)
Regulatory protein:
  • HSP70 (human)
  • PKCE (human)
Treatment
  • ATP
  • colforsin
  • EGF
  • hypoxia
  • phorbol_ester
  • PKC_inhibitor
  • pregnancy
  • U0126
  • VEGF
GJA1 (human) sPAkDCGsQkyAyFN S262-p
GJA1 (mouse) sPskDCGsPkyAyFN S262-p
GJA1 (rat) sPskDCGsPkyAyFN S262-p
GJA1 (rabbit) SPSKDCGSPKYAYFN S262
GJA1 (pig) sPSKDCGsPKYAYFN S262-p
GJA1 (hamster) NPSKDCGSPKYAYFN S262
GJA1 (cow) SPSKDCGSPKYAYFN S263
K264-ub
AkDCGsQkyAyFNGC
0 16
GJA1 (human) AkDCGsQkyAyFNGC K264-ub
GJA1 (mouse) skDCGsPkyAyFNGC K264-ub
GJA1 (rat) skDCGsPkyAyFNGC K264-ub
GJA1 (rabbit) SKDCGSPKYAYFNGC K264
GJA1 (pig) SKDCGsPKYAYFNGC K264
GJA1 (hamster) SKDCGSPKYAYFNGC K264
GJA1 (cow) SKDCGSPKYAYFNGC K265
Y265-p
kDCGsQkyAyFNGCs
Upstream
Downstream
21 13
Effects on Modified Protein
  • activity, inhibited
  • intracellular localization
  • molecular association, regulation
  • phosphorylation
  • protein conformation
  • protein processing
Effects on Biological Processes:
  • signaling pathway regulation
Kinase, in vitro:
  • Src (human)
Putative in vivo kinases:
  • Src (human)
  • Src (rat)
Treatment
  • 3-Methyladenine
  • ATP
  • ionizing_radiation
  • KX2-391
  • NAC
  • phorbol_ester
  • PP2
  • pregnancy
  • U0126
  • VEGF
GJA1 (human) kDCGsQkyAyFNGCs Y265-p
GJA1 (mouse) kDCGsPkyAyFNGCS Y265-p
GJA1 (rat) kDCGsPkyAyFNGCS Y265-p
GJA1 (rabbit) KDCGSPKYAYFNGCS Y265
GJA1 (pig) KDCGsPKYAYFNGCS Y265
GJA1 (hamster) KDCGSPKYAYFNGCS Y265
GJA1 (cow) KDCGSPKYAYFNGCS Y266
Y267-p
CGsQkyAyFNGCsSP
2 11
GJA1 (human) CGsQkyAyFNGCsSP Y267-p
GJA1 (mouse) CGsPkyAyFNGCSsP Y267-p
GJA1 (rat) CGsPkyAyFNGCSSP Y267-p
GJA1 (rabbit) CGSPKYAYFNGCSSP Y267
GJA1 (pig) CGsPKYAYFNGCSSP Y267
GJA1 (hamster) CGSPKYAYFNGCSSP Y267
GJA1 (cow) CGSPKYAYFNGCSSP Y268
S272-p
yAyFNGCsSPtAPLs
0 1
GJA1 (human) yAyFNGCsSPtAPLs S272-p
GJA1 (mouse) yAyFNGCSsPtAPLs S272
GJA1 (rat) yAyFNGCSSPTAPLs S272
GJA1 (rabbit) YAYFNGCSSPTAPLS S272
GJA1 (pig) YAYFNGCSSPTAPLs S272
GJA1 (hamster) YAYFNGCSSPTAPLS S272
GJA1 (cow) YAYFNGCSSPTAPLS S273
S273
AyFNGCsSPtAPLsP
0 2
GJA1 (human) AyFNGCsSPtAPLsP S273
GJA1 (mouse) AyFNGCSsPtAPLsP S273-p
GJA1 (rat) AyFNGCSSPTAPLsP S273
GJA1 (rabbit) AYFNGCSSPTAPLSP S273
GJA1 (pig) AYFNGCSSPTAPLsP S273
GJA1 (hamster) AYFNGCSSPTAPLSP S273
GJA1 (cow) AYFNGCSSPTAPLSP S274
T275-p
FNGCsSPtAPLsPMs
0 2
GJA1 (human) FNGCsSPtAPLsPMs T275-p
GJA1 (mouse) FNGCSsPtAPLsPMs T275-p
GJA1 (rat) FNGCSSPTAPLsPMs T275
GJA1 (rabbit) FNGCSSPTAPLSPMS T275
GJA1 (pig) FNGCSSPTAPLsPMs T275
GJA1 (hamster) FNGCSSPTAPLSPMS T275
GJA1 (cow) FNGCSSPTAPLSPMS T276
S279-p
sSPtAPLsPMsPPGy
Upstream
Downstream
38 6
Effects on Modified Protein
  • activity, inhibited
  • intracellular localization
  • molecular association, regulation
  • protein conformation
  • protein degradation
  • protein stabilization
  • ubiquitination
Effects on Biological Processes:
  • apoptosis, induced
  • carcinogenesis, inhibited
  • cytoskeletal reorganization
  • endocytosis, induced
  • signaling pathway regulation
Kinase, in vitro:
  • MAPKAPK2 (human)
Putative in vivo kinases:
  • P38A (human)
Treatment
  • ATP
  • cAMP_analog
  • CXCL12
  • EGF
  • phorbol_ester
  • PP2
  • pregnancy
  • pressure
  • SB202190
  • SB203580
  • sulforaphane
  • U0126
  • UV
  • VEGF
GJA1 (human) sSPtAPLsPMsPPGy S279-p
GJA1 (mouse) SsPtAPLsPMsPPGy S279-p
GJA1 (rat) SSPTAPLsPMsPPGY S279-p
GJA1 (rabbit) SSPTAPLSPMSPPGY S279
GJA1 (pig) SSPTAPLsPMsPPGY S279-p
GJA1 (hamster) SSPTAPLSPMSPPGY S279
GJA1 (cow) SSPTAPLSPMSPPGY S280
S282-p
tAPLsPMsPPGykLV
Upstream
Downstream
37 7
Effects on Modified Protein
  • activity, inhibited
  • intracellular localization
  • molecular association, regulation
  • protein conformation
  • protein degradation
  • protein stabilization
  • ubiquitination
Effects on Biological Processes:
  • apoptosis, induced
  • carcinogenesis, inhibited
  • cytoskeletal reorganization
  • endocytosis, induced
  • signaling pathway regulation
Kinase, in vitro:
  • MAPKAPK2 (human)
Putative in vivo kinases:
  • P38A (human)
Treatment
  • ATP
  • EGF
  • phorbol_ester
  • PP2
  • pregnancy
  • pressure
  • SB202190
  • SB203580
  • sulforaphane
  • U0126
  • UV
  • VEGF
GJA1 (human) tAPLsPMsPPGykLV S282-p
GJA1 (mouse) tAPLsPMsPPGykLV S282-p
GJA1 (rat) TAPLsPMsPPGYkLV S282-p
GJA1 (rabbit) TAPLSPMSPPGYKLV S282
GJA1 (pig) TAPLsPMsPPGYKLV S282-p
GJA1 (hamster) TAPLSPMSPPGYKLV S282
GJA1 (cow) TAPLSPMSPPGYKLV S283
Y286-p
sPMsPPGykLVtGDR
Downstream
1 12
Effects on Modified Protein
  • protein degradation
  • ubiquitination
GJA1 (human) sPMsPPGykLVtGDR Y286-p
GJA1 (mouse) sPMsPPGykLVtGDR Y286-p
GJA1 (rat) sPMsPPGYkLVTGDR Y286
GJA1 (rabbit) SPMSPPGYKLVTGDR Y286
GJA1 (pig) sPMsPPGYKLVTGDR Y286
GJA1 (hamster) SPMSPPGYKLVTGDR Y286
GJA1 (cow) SPMSPPGYKLVTGDR Y287
K287-ub
PMsPPGykLVtGDRN
0 7
GJA1 (human) PMsPPGykLVtGDRN K287-ub
GJA1 (mouse) PMsPPGykLVtGDRN K287-ub
GJA1 (rat) PMsPPGYkLVTGDRN K287-ub
GJA1 (rabbit) PMSPPGYKLVTGDRN K287
GJA1 (pig) PMsPPGYKLVTGDRN K287
GJA1 (hamster) PMSPPGYKLVTGDRN K287
GJA1 (cow) PMSPPGYKLVTGDRN K288
T290-p
PPGykLVtGDRNNss
0 5
GJA1 (human) PPGykLVtGDRNNss T290-p
GJA1 (mouse) PPGykLVtGDRNNss T290-p
GJA1 (rat) PPGYkLVTGDRNNss T290
GJA1 (rabbit) PPGYKLVTGDRNNSS T290
GJA1 (pig) PPGYKLVTGDRNNSS T290
GJA1 (hamster) PPGYKLVTGDRNNSS T290
GJA1 (cow) PPGYKLVTGDRNNSs T291
S296-p
VtGDRNNssCRNyNk
1 14
GJA1 (human) VtGDRNNssCRNyNk S296-p
GJA1 (mouse) VtGDRNNssCRNyNk S296-p
GJA1 (rat) VTGDRNNssCRNYNk S296-p
GJA1 (rabbit) VTGDRNNSSCRNYNK S296
GJA1 (pig) VTGDRNNSSCRNYNK S296
GJA1 (hamster) VTGDRNNSSCRNYNK S296
GJA1 (cow) VTGDRNNSsCRNYNK S297
S297-p
tGDRNNssCRNyNkQ
2 12
GJA1 (human) tGDRNNssCRNyNkQ S297-p
GJA1 (mouse) tGDRNNssCRNyNkQ S297-p
GJA1 (rat) TGDRNNssCRNYNkQ S297-p
GJA1 (rabbit) TGDRNNSSCRNYNKQ S297
GJA1 (pig) TGDRNNSSCRNYNKQ S297
GJA1 (hamster) TGDRNNSSCRNYNKQ S297
GJA1 (cow) TGDRNNSsCRNYNKQ S298-p
Y301-p
NNssCRNyNkQAsEQ
0 8
GJA1 (human) NNssCRNyNkQAsEQ Y301-p
GJA1 (mouse) NNssCRNyNkQAsEQ Y301-p
GJA1 (rat) NNssCRNYNkQAsEQ Y301
GJA1 (rabbit) NNSSCRNYNKQASEQ Y301
GJA1 (pig) NNSSCRNYNKQASEQ Y301
GJA1 (hamster) NNSSCRNYNKQASEQ Y301
GJA1 (cow) NNSsCRNYNKQASEQ Y302
K303-ub
ssCRNyNkQAsEQNW
0 30
GJA1 (human) ssCRNyNkQAsEQNW K303-ub
GJA1 (mouse) ssCRNyNkQAsEQNW K303-ub
GJA1 (rat) ssCRNYNkQAsEQNW K303-ub
GJA1 (rabbit) SSCRNYNKQASEQNW K303
GJA1 (pig) SSCRNYNKQASEQNW K303
GJA1 (hamster) SSCRNYNKQASEQNW K303
GJA1 (cow) SsCRNYNKQASEQNW K304
S306-p
RNyNkQAsEQNWANy
Upstream
1 22
Treatment
  • ischemia
GJA1 (human) RNyNkQAsEQNWANy S306-p
GJA1 (mouse) RNyNkQAsEQNWANy S306-p
GJA1 (rat) RNYNkQAsEQNWANy S306-p
GJA1 (rabbit) RNYNKQASEQNWANY S306
GJA1 (pig) RNYNKQASEQNWANY S306
GJA1 (hamster) RNYNKQASEQNWANY S306
GJA1 (cow) RNYNKQASEQNWANY S307
Y313-p
sEQNWANysAEQNRM
Upstream
Downstream
4 315
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
Kinase, in vitro:
  • Src (human)
Putative in vivo kinases:
  • Src (human)
Regulatory protein:
  • EGFR (human)
Treatment
  • ephrin_B1
  • FGF1
  • PD173074
GJA1 (human) sEQNWANysAEQNRM Y313-p
GJA1 (mouse) sEQNWANysAEQNRM Y313-p
GJA1 (rat) sEQNWANysAEQNRM Y313-p
GJA1 (rabbit) SEQNWANYSAEQNRM Y313
GJA1 (pig) SEQNWANYSAEQNRM Y313
GJA1 (hamster) SEQNWANYSAEQNRM Y313
GJA1 (cow) SEQNWANYSAEQNRM Y314
S314-p
EQNWANysAEQNRMG
0 12
GJA1 (human) EQNWANysAEQNRMG S314-p
GJA1 (mouse) EQNWANysAEQNRMG S314-p
GJA1 (rat) EQNWANysAEQNRMG S314-p
GJA1 (rabbit) EQNWANYSAEQNRMG S314
GJA1 (pig) EQNWANYSAEQNRMG S314
GJA1 (hamster) EQNWANYSAEQNRMG S314
GJA1 (cow) EQNWANYSAEQNRMG S315
S325-p
NRMGQAGstIsNsHA
Upstream
Downstream
8 13
Effects on Modified Protein
  • protein conformation
Kinase, in vitro:
  • CK1A (human)
GJA1 (human) NRMGQAGstIsNsHA S325-p
GJA1 (mouse) NRMGQAGstIsNsHA S325-p
GJA1 (rat) NRMGQAGstIsNsHA S325-p
GJA1 (rabbit) NRMGQAGSTISNSHA S325
GJA1 (pig) NRMGQAGSTISNSHA S325
GJA1 (hamster) NRMGQAGSTISNSHA S325
GJA1 (cow) NRMGQAGSTISNSHA S326
T326-p
RMGQAGstIsNsHAQ
0 11
GJA1 (human) RMGQAGstIsNsHAQ T326-p
GJA1 (mouse) RMGQAGstIsNsHAQ T326-p
GJA1 (rat) RMGQAGstIsNsHAQ T326-p
GJA1 (rabbit) RMGQAGSTISNSHAQ T326
GJA1 (pig) RMGQAGSTISNSHAQ T326
GJA1 (hamster) RMGQAGSTISNSHAQ T326
GJA1 (cow) RMGQAGSTISNSHAQ T327
S328-p
GQAGstIsNsHAQPF
Upstream
Downstream
8 12
Effects on Modified Protein
  • protein conformation
Kinase, in vitro:
  • CK1A (human)
GJA1 (human) GQAGstIsNsHAQPF S328-p
GJA1 (mouse) GQAGstIsNsHAQPF S328-p
GJA1 (rat) GQAGstIsNsHAQPF S328-p
GJA1 (rabbit) GQAGSTISNSHAQPF S328
GJA1 (pig) GQAGSTISNSHAQPF S328
GJA1 (hamster) GQAGSTISNSHAQPF S328
GJA1 (cow) GQAGSTISNSHAQPF S329
S330-p
AGstIsNsHAQPFDF
Upstream
Downstream
8 13
Effects on Modified Protein
  • protein conformation
Kinase, in vitro:
  • CK1A (human)
GJA1 (human) AGstIsNsHAQPFDF S330-p
GJA1 (mouse) AGstIsNsHAQPFDF S330-p
GJA1 (rat) AGstIsNsHAQPFDF S330-p
GJA1 (rabbit) AGSTISNSHAQPFDF S330
GJA1 (pig) AGSTISNSHAQPFDF S330
GJA1 (hamster) AGSTISNSHAQPFDF S330
GJA1 (cow) AGSTISNSHAQPFDF S331
N341
PFDFPDDNQNskkLA
0 2
GJA1 (human) PFDFPDDNQNskkLA N341
GJA1 (mouse) PFDFPDDsQNAkkVA S341-p
GJA1 (rat) PFDFPDDNQNAKKVA N341
GJA1 (rabbit) PFDFPDDNQNSKKLA N341
GJA1 (pig) PFDFPDDNQNSKKLD N341
GJA1 (hamster) PFDFPDDNQNAKKIA N341
GJA1 (cow) PFDFPDDHQNSKKLD H342
S344-p
FPDDNQNskkLAAGH
0 2
GJA1 (human) FPDDNQNskkLAAGH S344-p
GJA1 (mouse) FPDDsQNAkkVAAGH A344
GJA1 (rat) FPDDNQNAKKVAAGH A344
GJA1 (rabbit) FPDDNQNSKKLAAGH S344
GJA1 (pig) FPDDNQNSKKLDAGH S344
GJA1 (hamster) FPDDNQNAKKIAAGH A344
GJA1 (cow) FPDDHQNSKKLDAGH S345
K345-ub
PDDNQNskkLAAGHE
0 12
GJA1 (human) PDDNQNskkLAAGHE K345-ub
GJA1 (mouse) PDDsQNAkkVAAGHE K345-ub
GJA1 (rat) PDDNQNAKKVAAGHE K345
GJA1 (rabbit) PDDNQNSKKLAAGHE K345
GJA1 (pig) PDDNQNSKKLDAGHE K345
GJA1 (hamster) PDDNQNAKKIAAGHE K345
GJA1 (cow) PDDHQNSKKLDAGHE K346
K346-ub
DDNQNskkLAAGHEL
0 7
GJA1 (human) DDNQNskkLAAGHEL K346-ub
GJA1 (mouse) DDsQNAkkVAAGHEL K346-ub
GJA1 (rat) DDNQNAKKVAAGHEL K346
GJA1 (rabbit) DDNQNSKKLAAGHEL K346
GJA1 (pig) DDNQNSKKLDAGHEL K346
GJA1 (hamster) DDNQNAKKIAAGHEL K346
GJA1 (cow) DDHQNSKKLDAGHEL K347
S364-p
AIVDQRPssRAssRA
Upstream
Downstream
6 6
Effects on Modified Protein
  • protein conformation
Kinase, in vitro:
  • PKACA (human)
GJA1 (human) AIVDQRPssRAssRA S364-p
GJA1 (mouse) AIVDQRPssRAssRA S364-p
GJA1 (rat) AIVDQRPssRAssRA S364-p
GJA1 (rabbit) AIVDQRPSSRASsRA S364
GJA1 (pig) AIVDQRPSSRAsSRA S364
GJA1 (hamster) AIVDQRPSSRASSRA S364
GJA1 (cow) AIVDQRPSSRASSRA S365
S365-p
IVDQRPssRAssRAs
Upstream
Downstream
14 15
Effects on Modified Protein
  • protein conformation
Kinase, in vitro:
  • PKACA (human)
Treatment
  • CAIP
  • ciclosporin
  • low Na
  • metastatic potential
  • tautomycin
  • Tyrode's
GJA1 (human) IVDQRPssRAssRAs S365-p
GJA1 (mouse) IVDQRPssRAssRAs S365-p
GJA1 (rat) IVDQRPssRAssRAs S365-p
GJA1 (rabbit) IVDQRPSSRASsRAS S365
GJA1 (pig) IVDQRPSSRAsSRAS S365
GJA1 (hamster) IVDQRPSSRASSRAS S365
GJA1 (cow) IVDQRPSSRASSRAS S366
S368-p
QRPssRAssRAssRP
Upstream
Downstream
40 7
GJA1 (human)
S368-p
GJA1 (mouse)
S368-p
GJA1 (rat)
S368-p
Effects on Modified Protein
  • activity, inhibited
  • molecular association, regulation
  • protein conformation
  • protein stabilization
Effects on Biological Processes:
  • apoptosis, induced
  • carcinogenesis, inhibited
  • cell motility, altered
  • endocytosis, induced
Kinase, in vitro:
  • PKCA (human)
  • PKCE (human)
Putative in vivo kinases:
  • PKCE (human)
Regulatory protein:
  • HSP70 (human)
Treatment
  • AMP-PNP
  • ATP
  • BIO
  • bisindolylmaleimide
  • CAIP
  • chelerythrine
  • ciclosporin
  • EGF
  • Go_6976
  • hypoxia
  • levonorgestrel/norgestrel
  • low Na
  • phorbol_ester
  • PP2
  • Ro31-8220
  • SP600125
  • staurosporine
  • sulforaphane
  • tautomycin
  • Tyrode's
  • U0126
  • VEGF
  • wounding
GJA1 (human) QRPssRAssRAssRP S368-p
GJA1 (mouse) QRPssRAssRAssRP S368-p
GJA1 (rat) QRPssRAssRAssRP S368-p
GJA1 (rabbit) QRPSSRASsRASSRP S368
GJA1 (pig) QRPSSRAsSRASSRP S368-p
GJA1 (hamster) QRPSSRASSRASSRP S368
GJA1 (cow) QRPSSRASSRASSRP S369
S369-p
RPssRAssRAssRPR
Upstream
Downstream
14 9
Effects on Modified Protein
  • intracellular localization
  • protein conformation
Kinase, in vitro:
  • PKACA (human)
Putative in vivo kinases:
  • PKACA (human)
Treatment
  • cAMP_analog
GJA1 (human) RPssRAssRAssRPR S369-p
GJA1 (mouse) RPssRAssRAssRPR S369-p
GJA1 (rat) RPssRAssRAssRPR S369-p
GJA1 (rabbit) RPSSRASsRASSRPR S369-p
GJA1 (pig) RPSSRAsSRASSRPR S369
GJA1 (hamster) RPSSRASSRASSRPR S369
GJA1 (cow) RPSSRASSRASSRPR S370
S372-p
sRAssRAssRPRPDD
Upstream
Downstream
4 6
Effects on Modified Protein
  • protein conformation
Kinase, in vitro:
  • PKCA (human)
Treatment
  • cAMP_analog
GJA1 (human) sRAssRAssRPRPDD S372-p
GJA1 (mouse) sRAssRAssRPRPDD S372-p
GJA1 (rat) sRAssRAssRPRPDD S372-p
GJA1 (rabbit) SRASsRASSRPRPDD S372
GJA1 (pig) SRAsSRASSRPRPDD S372
GJA1 (hamster) SRASSRASSRPRPDD S372
GJA1 (cow) SRASSRASSRPRPDD S373
S373-p
RAssRAssRPRPDDL
Upstream
Downstream
15 6
Effects on Modified Protein
  • activity, induced
  • intracellular localization
  • molecular association, regulation
  • protein conformation
Kinase, in vitro:
  • Akt1 (human)
  • PKACA (human)
Putative in vivo kinases:
  • Akt1 (human)
  • PKACA (human)
Treatment
  • Akt_inhibitor_IV
  • cAMP_analog
  • deoxygenation
  • hypoxia
  • mechanical stress
  • phorbol_ester
  • scratch wound
GJA1 (human) RAssRAssRPRPDDL S373-p
GJA1 (mouse) RAssRAssRPRPDDL S373-p
GJA1 (rat) RAssRAssRPRPDDL S373-p
GJA1 (rabbit) RASsRASSRPRPDDL S373
GJA1 (pig) RAsSRASSRPRPDDL S373
GJA1 (hamster) RASSRASSRPRPDDL S373
GJA1 (cow) RASSRASSRPRPDDL S374