Other Species / Isoforms
  PROX1 (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

  HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
S79-p
KLLKRANsyEDAMMP
Upstream
Downstream
1 16
Effects on Modified Protein
  • molecular association, regulation
  • protein degradation
  • ubiquitination
Effects on Biological Processes:
  • carcinogenesis, inhibited
  • cell growth, inhibited
  • signaling pathway regulation
  • transcription, induced
Kinase, in vitro:
  • AMPKA2 (human)
  • AMPKB1 (human)
Putative in vivo kinases:
  • AMPKA2 (human)
Treatment
  • fasting
  • glucose_starvation
  • metformin
  • siRNA
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PROX1 (human) KLLKRANsyEDAMMP S79-p
PROX1 (mouse) KLLKRANsYEDAMMP S79-p
PROX1 (rat) KLLKRANsYEDAMMP S79-p
Y80-p
LLKRANsyEDAMMPF
0 1
PROX1 (human) LLKRANsyEDAMMPF Y80-p
PROX1 (mouse) LLKRANsYEDAMMPF Y80
PROX1 (rat) LLKRANsYEDAMMPF Y80
T91-p
MMPFPGAtIIsQLLK
0 1
PROX1 (human) MMPFPGAtIIsQLLK T91-p
PROX1 (mouse) MMPFPGATIISQLLK T91
PROX1 (rat) MMPFPGATIISQLLK T91
S94-p
FPGAtIIsQLLKNNM
0 1
PROX1 (human) FPGAtIIsQLLKNNM S94-p
PROX1 (mouse) FPGATIISQLLKNNM S94
PROX1 (rat) FPGATIISQLLKNNM S94
S142
DSPPECLSPFGRPTM
0 1
PROX1 (human) DSPPECLSPFGRPTM S142
PROX1 (mouse) DSPPECLsPFGRPTM S142-p
PROX1 (rat) DSPPECLSPFGRPTM S142
S177-p
ENIIRGMsHsPsVAL
0 6
PROX1 (human) ENIIRGMsHsPsVAL S177-p
PROX1 (mouse) ENIIRGMsHsPsVAL S177-p
PROX1 (rat) ENIIRGMsHsPSVAL S177-p
S179-p
IIRGMsHsPsVALRG
0 13
PROX1 (human) IIRGMsHsPsVALRG S179-p
PROX1 (mouse) IIRGMsHsPsVALRG S179-p
PROX1 (rat) IIRGMsHsPSVALRG S179-p
S181-p
RGMsHsPsVALRGNE
0 3
PROX1 (human) RGMsHsPsVALRGNE S181-p
PROX1 (mouse) RGMsHsPsVALRGNE S181-p
PROX1 (rat) RGMsHsPSVALRGNE S181
S197-p
EREMAPQsVsPRESY
0 8
PROX1 (human) EREMAPQsVsPRESY S197-p
PROX1 (mouse) EREMAPQsVsPRESY S197-p
PROX1 (rat) EREMAPQSVsPRESY S197
S199-p
EMAPQsVsPRESYRE
0 25
PROX1 (human) EMAPQsVsPRESYRE S199-p
PROX1 (mouse) EMAPQsVsPRESYRE S199-p
PROX1 (rat) EMAPQSVsPRESYRE S199-p
K212
RENKRKQKLPQQQQQ
0 1
PROX1 (human) RENKRKQKLPQQQQQ K212
PROX1 (mouse) RENKRKQkLPQQQQQ K212-ub
PROX1 (rat) RENKRKQKLPQQQQQ K212
S291-p
LDARAQDsVGRsDNE
0 5
PROX1 (human) LDARAQDsVGRsDNE S291-p
PROX1 (mouse) LDARAQDsVGRsDNE S291-p
PROX1 (rat) LDARAQDsVGRsDNE S291-p
S295-p
AQDsVGRsDNEMCEL
0 8
PROX1 (human) AQDsVGRsDNEMCEL S295-p
PROX1 (mouse) AQDsVGRsDNEMCEL S295-p
PROX1 (rat) AQDsVGRsDNEMCEL S295-p
K353-sm
KHLAETLkQELNTAM
Downstream
1 0
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
Effects on Biological Processes:
  • transcription, induced
PROX1 (human) KHLAETLkQELNTAM K353-sm
PROX1 (mouse) KHLAETLKQELNTAM K353
PROX1 (rat) KHLAETLKQELNTAM K353
S372-p
DTVVKVFsAKPSRQV
0 1
PROX1 (human) DTVVKVFsAKPSRQV S372-p
PROX1 (mouse) DTVVKVFSAKPSRQV S372
PROX1 (rat) DTVVKVFSAKPSRQV S372
R392
PLQIPQARFAVNGEN
0 1
PROX1 (human) PLQIPQARFAVNGEN R392
PROX1 (mouse) PLQIPQArFAVNGEN R392-m1
PROX1 (rat) PLQIPQARFAVNGEN R392
S432
GNVQMASSTDQTEAL
0 1
PROX1 (human) GNVQMASSTDQTEAL S432
PROX1 (mouse) GSVQMPSsTDQTEAL S432-p
PROX1 (rat) GNVQMPSSTDQTEAL S432
T472
HQSPLSATTGFTTST
0 1
PROX1 (human) HQSPLSATTGFTTST T472
PROX1 (mouse) HQSPLSAtAGFTTPS T472-p
PROX1 (rat) HQSPLSATAGFTTPS T472
S495
LMAYPFQSPLGAPSG
0 10
PROX1 (human) LMAYPFQSPLGAPSG S495
PROX1 (mouse) LMAYPFQsPLGAPSG S495-p
PROX1 (rat) LMAYPFQSPLGAPSG S495
S511-p
FSGKDRAsPEsLDLT
0 31
PROX1 (human) FSGKDRAsPEsLDLT S511-p
PROX1 (mouse) FSGKDRAsPEsLDLt S511-p
PROX1 (rat) FSGKDRAsPEsLDLT S511-p
S514-p
KDRAsPEsLDLTRDT
0 12
PROX1 (human) KDRAsPEsLDLTRDT S514-p
PROX1 (mouse) KDRAsPEsLDLtRDT S514-p
PROX1 (rat) KDRAsPEsLDLTRDT S514-p
T518
sPEsLDLTRDTTSLR
0 1
PROX1 (human) sPEsLDLTRDTTSLR T518
PROX1 (mouse) sPEsLDLtRDTTSLR T518-p
PROX1 (rat) sPEsLDLTRDTTSLR T518
S529
TSLRTKMSSHHLSHH
0 1
PROX1 (human) TSLRTKMSSHHLSHH S529
PROX1 (mouse) TSLRTKMssHHLSHH S529-p
PROX1 (rat) TSLRTKMSSHHLSHH S529
S530
SLRTKMSSHHLSHHP
0 1
PROX1 (human) SLRTKMSSHHLSHHP S530
PROX1 (mouse) SLRTKMssHHLSHHP S530-p
PROX1 (rat) SLRTKMSSHHLSHHP S530
S539-p
HLSHHPCsPAHPPST
0 7
PROX1 (human) HLSHHPCsPAHPPST S539-p
PROX1 (mouse) HLSHHPCsPAHPPsT S539-p
PROX1 (rat) HLSHHPCSPAHPPST S539
S545
CsPAHPPSTAEGLSL
0 1
PROX1 (human) CsPAHPPSTAEGLSL S545
PROX1 (mouse) CsPAHPPsTAEGLSL S545-p
PROX1 (rat) CSPAHPPSTAEGLSL S545
S553-p
TAEGLSLsLIksECG
0 1
PROX1 (human) TAEGLSLsLIksECG S553-p
PROX1 (mouse) TAEGLSLSLIkSECG S553
PROX1 (rat) TAEGLSLSLIKSECG S553
K556-sm
GLSLsLIksECGDLQ
Downstream
3 1
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
Effects on Biological Processes:
  • cell growth, induced
  • transcription, induced
PROX1 (human) GLSLsLIksECGDLQ K556-sm
PROX1 (mouse) GLSLSLIkSECGDLQ K556-sm
PROX1 (rat) GLSLSLIKSECGDLQ K556
S557-p
LSLsLIksECGDLQD
0 2
PROX1 (human) LSLsLIksECGDLQD S557-p
PROX1 (mouse) LSLSLIkSECGDLQD S557
PROX1 (rat) LSLSLIKSECGDLQD S557
S569
LQDMSEISPYSGSAM
0 4
PROX1 (human) LQDMSEISPYSGSAM S569
PROX1 (mouse) LQDMSDIsPySGsAM S569-p
PROX1 (rat) LQDMSDISPYSGSAM S569
Y571
DMSEISPYSGSAMQE
0 2
PROX1 (human) DMSEISPYSGSAMQE Y571
PROX1 (mouse) DMSDIsPySGsAMQE Y571-p
PROX1 (rat) DMSDISPYSGSAMKG Y571
S574
EISPYSGSAMQEGLS
0 1
PROX1 (human) EISPYSGSAMQEGLS S574
PROX1 (mouse) DIsPySGsAMQEGLS S574-p
PROX1 (rat) DISPYSGSAMKGYHP S574
K611
KTYFSDVKFNRCITS
0 1
PROX1 (human) KTYFSDVKFNRCITS K611
PROX1 (mouse) KTYFSDVkFNRCITS K611-ub
PROX1 (rat) gap -
T650
INDGVTSTEELSITR
0 1
PROX1 (human) INDGVTSTEELSITR T650
PROX1 (mouse) INDGVTStEELSITR T650-p
PROX1 (rat) gap -
K700
FNAIIAGKDVDPSWk
0 1
PROX1 (human) FNAIIAGKDVDPSWk K700
PROX1 (mouse) FNAIIAGkDVDPSWK K700-ub
PROX1 (rat) gap -
K707-ac
KDVDPSWkkAIYKVI
0 1
PROX1 (human) KDVDPSWkkAIYKVI K707-ac
PROX1 (mouse) kDVDPSWKKAIYKVI K707
PROX1 (rat) gap -
K708-ac
DVDPSWkkAIYKVIC
0 1
PROX1 (human) DVDPSWkkAIYKVIC K708-ac
PROX1 (mouse) DVDPSWKKAIYKVIC K708
PROX1 (rat) gap -
K716
AIYKVICKLDSEVPE
0 1
PROX1 (human) AIYKVICKLDSEVPE K716
PROX1 (mouse) AIYKVICkLDSEVPE K716-ub
PROX1 (rat) gap -