Other Species / Isoforms
  C/EBP-alpha (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

  HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
S21-p
PMSSHLQsPPHAPSS
Upstream
Downstream
10 1
C/EBP-alpha (human)
S21-p
C/EBP-alpha (mouse)
S21-p
C/EBP-alpha (rat)
S21-p
Effects on Modified Protein
  • activity, induced
  • activity, inhibited
  • molecular association, regulation
  • protein conformation
Effects on Biological Processes:
  • cell differentiation, altered
  • cell differentiation, inhibited
  • transcription, altered
  • transcription, inhibited
Kinase, in vitro:
  • ERK1 (human)
  • ERK2 (human)
Putative in vivo kinases:
  • ERK1 (human)
  • ERK2 (human)
Regulatory protein:
  • CD34 (human)
  • FUT4 (human)
  • TfR (human)
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Treatment
  • AG1296
  • butyrate
  • FL
  • hemin
  • imatinib
  • insulin
  • IRC-084864
  • MLN-518
  • PD98059
  • PDGF
  • phorbol_ester
  • serum
  • U0126
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C/EBP-alpha (human) PMSSHLQsPPHAPSS S21-p
C/EBP-alpha (mouse) PMSSHLQsPPHAPSN S21-p
C/EBP-alpha (rat) PMSSHLQsPPHAPSN S21-p
K161-ac
ALRPLVIkQEPREED
Upstream
0 2
Treatment
  • vorinostat
C/EBP-alpha (human) ALRPLVIkQEPREED K161-ac
C/EBP-alpha (mouse) ALRPLVIKQEPREED K159
C/EBP-alpha (rat) ALRPLVIkQEPREED K159-ac
K161-ub
ALRPLVIkQEPREED
Upstream
0 1
Treatment
  • MG132
C/EBP-alpha (human) ALRPLVIkQEPREED K161-ub
C/EBP-alpha (mouse) ALRPLVIKQEPREED K159
C/EBP-alpha (rat) ALRPLVIKQEPREED K159
K161-sm
ALRPLVIkQEPREED
Upstream
Downstream
3 1
Effects on Biological Processes:
  • cell differentiation, inhibited
  • transcription, inhibited
Regulatory protein:
  • C/EBP-alpha (human)
Treatment
  • siRNA
C/EBP-alpha (human) ALRPLVIkQEPREED K161-sm
C/EBP-alpha (mouse) ALRPLVIkQEPREED K159-sm
C/EBP-alpha (rat) ALRPLVIkQEPREED K159-sm
S190-p
PPPPPPPsHPHPHPP
Downstream
1 0
Effects on Biological Processes:
  • carcinogenesis, inhibited
  • cell differentiation, induced
  • cell growth, inhibited
C/EBP-alpha (human) PPPPPPPsHPHPHPP S190-p
C/EBP-alpha (mouse) gap -
C/EBP-alpha (rat) gap -
P197
sHPHPHPPPAHLAAP
13 0
C/EBP-alpha (human) sHPHPHPPPAHLAAP P197
C/EBP-alpha (mouse) PPPHPHAsPAHLAAP S193-p
C/EBP-alpha (rat) PPPHPHAsPAHLAAP S193-p
T226
HLQPGHPTPPPTPVP
8 0
C/EBP-alpha (human)
T226-p
C/EBP-alpha (mouse)
T222-p
C/EBP-alpha (rat)
T222-p
C/EBP-alpha (human) HLQPGHPTPPPTPVP T226
C/EBP-alpha (mouse) HLQPGHPtPPPtPVP T222-p
C/EBP-alpha (rat) HLQPGHPtPPPtPVP T222-p
T230
GHPTPPPTPVPsPHP
8 0
C/EBP-alpha (human)
T230-p
C/EBP-alpha (mouse)
T226-p
C/EBP-alpha (rat)
T226-p
C/EBP-alpha (human) GHPTPPPTPVPsPHP T230
C/EBP-alpha (mouse) GHPtPPPtPVPsPHA T226-p
C/EBP-alpha (rat) GHPtPPPtPVPsPHP T226-p
S234-p
PPPTPVPsPHPAPAL
4 0
C/EBP-alpha (human) PPPTPVPsPHPAPAL S234-p
C/EBP-alpha (mouse) PPPtPVPsPHAAPAL S230-p
C/EBP-alpha (rat) PPPtPVPsPHPAPAM S230-p
A252
GLPGPGSALKGLGAA
4 0
C/EBP-alpha (human) GLPGPGSALKGLGAA A252
C/EBP-alpha (mouse) GLPGPGSALKGLAGA A248
C/EBP-alpha (rat) GLPGPGGsLKGLAGP S248-p
S266-p
AHPDLRAsGGSGAGK
0 1
C/EBP-alpha (human) AHPDLRAsGGSGAGK S266-p
C/EBP-alpha (mouse) AHPDLRTGGGGGGSG G262
C/EBP-alpha (rat) PHPDLRTGGGGGGGA G262
K298-ac
RNNIAVRkSRDkAKQ
Upstream
Downstream
1 0
Effects on Modified Protein
  • molecular association, regulation
Effects on Biological Processes:
  • cell differentiation, inhibited
  • transcription, inhibited
Treatment
  • G-CSF
C/EBP-alpha (human) RNNIAVRkSRDkAKQ K298-ac
C/EBP-alpha (mouse) RNNIAVRKSRDKAKQ K299
C/EBP-alpha (rat) RNNIAVRKSRDKAKQ K298
K302-ac
AVRkSRDkAKQRNVE
Upstream
Downstream
1 0
Effects on Modified Protein
  • molecular association, regulation
Effects on Biological Processes:
  • cell differentiation, inhibited
  • transcription, inhibited
Treatment
  • G-CSF
C/EBP-alpha (human) AVRkSRDkAKQRNVE K302-ac
C/EBP-alpha (mouse) AVRKSRDKAKQRNVE K303
C/EBP-alpha (rat) AVRKSRDKAKQRNVE K302
K313-ub
RNVETQQkVLELTSD
0 1
C/EBP-alpha (human) RNVETQQkVLELTSD K313-ub
C/EBP-alpha (mouse) RNVETQQKVLELTSD K314
C/EBP-alpha (rat) RNVETQQKVLELTSD K313
K326-ac
SDNDRLRkRVEQLsR
Downstream
1 0
Effects on Biological Processes:
  • cell differentiation, inhibited
C/EBP-alpha (human) SDNDRLRkRVEQLsR K326-ac
C/EBP-alpha (mouse) SDNDRLRKRVEQLSR K327
C/EBP-alpha (rat) SDNDRLRKRVEQLSR K326
S332-p
RkRVEQLsRELDTLR
0 1
C/EBP-alpha (human) RkRVEQLsRELDTLR S332-p
C/EBP-alpha (mouse) RKRVEQLSRELDTLR S333
C/EBP-alpha (rat) RKRVEQLSRELDTLR S332