Other Species / Isoforms human rat

BAD (mouse)

LTP

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

HTP

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

S20-p

HALGLRKsDPGIRsL

0

1

BAD (human)	gap	-
BAD (mouse)	HALGLRKsDPGIRsL	S20-p
BAD (rat)	HALGLRKSDPGIRSL	S20

S26-p

KsDPGIRsLGSDAGG

Upstream

Downstream

1

1

Effects on Modified Protein

activity, inhibited
intracellular localization
molecular association, regulation
phosphorylation

Effects on Biological Processes:

apoptosis, inhibited

Kinase, in vitro:

IKKB (mouse)

Putative in vivo kinases:

IKKB (mouse)

Regulatory protein:

NFkB-p65 (mouse)

Treatment

siRNA
TNF

BAD (human)	gap	-
BAD (mouse)	KsDPGIRsLGSDAGG	S26-p
BAD (rat)	KSDPGIRSLGSDAGG	S26

S67

TDRGLGPSLTEDQPG

0

11

BAD (human)	AERGLGPsPAGDGPs	S25-p
BAD (mouse)	TDRGLGPSLTEDQPG	S67
BAD (rat)	TDRGLGPSLTEDQPG	S67

-

gap

0

2

BAD (human)	sPAGDGPsGsGkHHR	S32-p
BAD (mouse)	gap	-
BAD (rat)	gap	-

-

gap

0

3

BAD (human)	AGDGPsGsGkHHRQA	S34-p
BAD (mouse)	gap	-
BAD (rat)	gap	-

P75

LTEDQPGPyLAPGLL

0

1

BAD (human)	DGPsGsGkHHRQAPG	K36-ac
BAD (mouse)	LTEDQPGPyLAPGLL	P75
BAD (rat)	LTEDQPGPYLAPGLL	P75

Y76-p

TEDQPGPyLAPGLLG

0

2

BAD (human)	GPsGsGkHHRQAPGL	H37
BAD (mouse)	TEDQPGPyLAPGLLG	Y76-p
BAD (rat)	TEDQPGPYLAPGLLG	Y76

T94-p

HQQGRAAtNsHHGGA

Upstream

1

0

Kinase, in vitro:

Pim3 (mouse)

BAD (human)	HQQEQPTSSSHHGGA	S57
BAD (mouse)	HQQGRAAtNsHHGGA	T94-p
BAD (rat)	QQPGQAANNSHHGGA	N95

S96-p

QGRAAtNsHHGGAGA

Upstream

1

2

Kinase, in vitro:

Pim3 (mouse)

Treatment

insulin

BAD (human)	QEQPTSSSHHGGAGA	S59
BAD (mouse)	QGRAAtNsHHGGAGA	S96-p
BAD (rat)	PGQAANNSHHGGAGT	S97

S108-p

AGAMETRsRHssyPA

Upstream

0

31

Treatment

antibody

BAD (human)	AGAVEIRsRHssyPA	S71-p
BAD (mouse)	AGAMETRsRHssyPA	S108-p
BAD (rat)	AGTMETRSRHssYPA	S109

S111-p

METRsRHssyPAGtE

2

80

BAD (human)	VEIRsRHssyPAGtE	S74-p
BAD (mouse)	METRsRHssyPAGtE	S111-p
BAD (rat)	METRSRHssYPAGtE	S112-p

S112-p

ETRsRHssyPAGtEE

Upstream

Downstream

135

193

BAD (human)
S75-p

BAD (mouse)
S112-p

BAD (rat)
S113-p

Effects on Modified Protein

activity, induced
intracellular localization
molecular association, regulation

Effects on Biological Processes:

apoptosis, altered
apoptosis, inhibited

Kinase, in vitro:

Akt1 (human)
Akt1 (mouse)
JNK1 (mouse)
MSK1 (mouse)
p90RSK (human)
p90RSK (mouse)
PAK1 (human)
PAK5 (mouse)
Pim1 (human)
Pim1 (mouse)
Pim2 (human)
Pim3 (mouse)
PKACA (cow)
PKACA (human)
PKACA (mouse)
RAF1 (human)
RSK2 (mouse)

Putative in vivo kinases:

Akt1 (mouse)
JNK1 (mouse)
MSK1 (mouse)
p90RSK (human)
p90RSK (mouse)
PAK5 (mouse)
Pim1 (human)
Pim1 (mouse)
Pim2 (human)
Pim3 (human)
PKACA (mouse)
RSK2 (mouse)

Putative upstream phosphatases:

PPP2CA (mouse)

Regulatory protein:

ARRB1 (mouse)
BAFF (mouse)
BAG1 (mouse)
BCR-ABL1 (human)
DUSP1 (mouse)
FGFR1 (human)
FLT3 (human)
GILZ (human)
GRB10 (mouse)
IKKA (mouse)
IKKB (mouse)
JNK1 (mouse)
Kit (human)
Kit (mouse)
NFkB-p100 (mouse)
NFkB-p105 (mouse)
p90RSK (human)
p90RSK (mouse)
Pim1 (human)
Pim2 (human)
Pim3 (human)
PKACA (human)
PKIA (human)
PPP2CA (mouse)
RAF1 (mouse)
RICTOR (mouse)
RSK2 (human)
RSK3 (human)
TCL1A (mouse)
TFEB (human)

Treatment

BAD (human)	EIRsRHssyPAGtED	S75-p
BAD (mouse)	ETRsRHssyPAGtEE	S112-p
BAD (rat)	ETRSRHssYPAGtEE	S113-p

Y113-p

TRsRHssyPAGtEED

0

52

BAD (human)	IRsRHssyPAGtEDD	Y76-p
BAD (mouse)	TRsRHssyPAGtEED	Y113-p
BAD (rat)	TRSRHssYPAGtEED	Y114

T117-p

HssyPAGtEEDEGME

Upstream

1

32

Kinase, in vitro:

CK2A1 (rat)

Treatment

insulin

BAD (human)	HssyPAGtEDDEGMG	T80-p
BAD (mouse)	HssyPAGtEEDEGME	T117-p
BAD (rat)	HssYPAGtEEDEGME	T118-p

S128-p

EGMEEELsPFRGRsR

Upstream

Downstream

8

46

Effects on Modified Protein

molecular association, regulation

Effects on Biological Processes:

apoptosis, induced

Kinase, in vitro:

CDK1 (human)
CDK1 (mouse)
JNK1 (mouse)

Regulatory protein:

MEKK1 (mouse)

Treatment

anisomycin
aphidicolin
insulin
nocodazole
okadaic_acid
SB203580
seliciclib
SP600125
staurosporine
taxol

BAD (human)	EGMGEEPsPFrGrsR	S91-p
BAD (mouse)	EGMEEELsPFRGRsR	S128-p
BAD (rat)	EGMEEELsPFRGRsR	S129-p

R131

EEELsPFRGRsRsAP

1

0

BAD (human)	GEEPsPFrGrsRsAP	R94-m2
BAD (mouse)	EEELsPFRGRsRsAP	R131
BAD (rat)	EEELsPFRGRsRsAP	R132

R133

ELsPFRGRsRsAPPN

1

0

BAD (human)	EPsPFrGrsRsAPPN	R96-m2
BAD (mouse)	ELsPFRGRsRsAPPN	R133
BAD (rat)	ELsPFRGRsRsAPPN	R134

S134-p

LsPFRGRsRsAPPNL

1

25

BAD (human)	PsPFrGrsRsAPPNL	S97-p
BAD (mouse)	LsPFRGRsRsAPPNL	S134-p
BAD (rat)	LsPFRGRsRsAPPNL	S135-p

S136-p

PFRGRsRsAPPNLWA

Upstream

Downstream

136

267

BAD (human)
S99-p

BAD (mouse)
S136-p

BAD (rat)
S137-p

Effects on Modified Protein

activity, induced
activity, inhibited
intracellular localization
molecular association, regulation
phosphorylation

Effects on Biological Processes:

apoptosis, altered
apoptosis, inhibited
cell growth, altered

Kinase, in vitro:

Akt1 (human)
Akt1 (mouse)
p90RSK (human)
PAK1 (human)
Pim1 (human)
Pim1 (mouse)
Pim3 (mouse)
PKACA (cow)
PKACA (human)
PKACA (mouse)

Putative in vivo kinases:

Akt1 (human)
Akt1 (mouse)
Pim1 (human)
Pim2 (human)
Pim3 (human)
PKACA (mouse)

Putative upstream phosphatases:

PPP2CA (mouse)

Regulatory protein:

ASK1 (human)
BAG1 (mouse)
BCR-ABL1 (human)
BRAF iso1 (mouse)
ERK5 (human)
FLT3 (human)
FLT3 (mouse)
GILZ (human)
GRB10 (mouse)
IGF1 (mouse)
IKKB (mouse)
Kit (human)
MCF2 (human)
MEK5 (human)
NOX4 (human)
NRas (mouse)
Pim1 (human)
PTGER4 (mouse)
RAF1 (mouse)
TCL1A (mouse)

Treatment

BAD (human)	PFrGrsRsAPPNLWA	S99-p
BAD (mouse)	PFRGRsRsAPPNLWA	S136-p
BAD (rat)	PFRGRsRsAPPNLWA	S137-p

Y147

NLWAAQRYGRELRRM

0

1

BAD (human)	NLWAAQRyGRELRRM	Y110-p
BAD (mouse)	NLWAAQRYGRELRRM	Y147
BAD (rat)	NLWAAQRYGRELRRM	Y148

S155-p

GRELRRMsDEFEGsF

Upstream

Downstream

48

229

BAD (human)
S118-p

9297 : Phospho-Bad (Ser155) Antibody

BAD (mouse)
S155-p

9297 : Phospho-Bad (Ser155) Antibody

Effects on Modified Protein

intracellular localization
molecular association, regulation

Effects on Biological Processes:

apoptosis, altered
apoptosis, inhibited

Kinase, in vitro:

Akt1 (mouse)
MSK1 (human)
p90RSK (human)
p90RSK (mouse)
Pim1 (human)
Pim3 (mouse)
PKACA (cow)
PKACA (human)
PKACA (mouse)
PKG1 (human)

Putative in vivo kinases:

Akt1 (mouse)
Pim1 (human)
Pim2 (human)
Pim3 (human)
PKACA (human)
PKACA (mouse)
PKG1 (mouse)

Regulatory protein:

BAG1 (mouse)
GRB10 (mouse)
IKKB (mouse)
p90RSK (human)
p90RSK (rat)
PKACA (human)
PKAR1A (mouse)
PTGER4 (mouse)
RAF1 (mouse)
RSK2 (human)
RSK3 (human)

Treatment

BAD (human)	GRELRRMsDEFVDsF	S118-p
BAD (mouse)	GRELRRMsDEFEGsF	S155-p
BAD (rat)	GRELRRMsDEFEGSF	S156-p

S161-p

MsDEFEGsFKGLPRP

1

4

BAD (human)	MsDEFVDsFKKGLPR	S124-p
BAD (mouse)	MsDEFEGsFKGLPRP	S161-p
BAD (rat)	MsDEFEGSFKGLPRP	S162

S170-p

KGLPRPKsAGtATQM

Upstream

Downstream

6

27

Effects on Biological Processes:

apoptosis, inhibited
cell cycle regulation
cell growth, inhibited

Kinase, in vitro:

CAMK2G (human)
Pim3 (mouse)

Treatment

insulin
LY294002

BAD (human)	KGLPRPKsAGtAtQM	S134-p
BAD (mouse)	KGLPRPKsAGtATQM	S170-p
BAD (rat)	KGLPRPKSAGTATQM	S171

T173-p

PRPKsAGtATQMRQS

Upstream

2

0

Kinase, in vitro:

Pim3 (mouse)

BAD (human)	PRPKsAGtAtQMRQS	T137-p
BAD (mouse)	PRPKsAGtATQMRQS	T173-p
BAD (rat)	PRPKSAGTATQMRQs	T174

T175

PKsAGtATQMRQSAG

0

1

BAD (human)	PKsAGtAtQMRQSSs	T139-p
BAD (mouse)	PKsAGtATQMRQSAG	T175
BAD (rat)	PKSAGTATQMRQsAs	T176

S180

tATQMRQSAGWTRII

0

1

BAD (human)	tAtQMRQSSsWTRVF	S144
BAD (mouse)	tATQMRQSAGWTRII	S180
BAD (rat)	TATQMRQsAsWTRII	S181-p

G182

TQMRQSAGWTRIIQS

0

3

BAD (human)	tQMRQSSsWTRVFQS	S146-p
BAD (mouse)	TQMRQSAGWTRIIQS	G182
BAD (rat)	TQMRQsAsWTRIIQS	S183-p

K197

WWDRNLGKGGStPSQ

0

22

BAD (human)	WWDRNLGrGSSAPSQ	R161-m1
BAD (mouse)	WWDRNLGKGGStPSQ	K197
BAD (rat)	WWDRNLGKGGSTPSQ	K198

T201-p

NLGKGGStPSQ____

Upstream

Downstream

3

0

Effects on Modified Protein

activity, induced
molecular association, regulation

Effects on Biological Processes:

apoptosis, inhibited

Kinase, in vitro:

JNK1 (human)
JNK1 (mouse)

Putative in vivo kinases:

JNK1 (human)
JNK1 (mouse)

Treatment

IL-3
serum
UV

BAD (human)	NLGrGSSAPSQ____	A165
BAD (mouse)	NLGKGGStPSQ____	T201-p
BAD (rat)	NLGKGGSTPSQ____	T202