Other Species / Isoforms
  FOXO4 (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

 HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
S26-p
DPDFEPQsRPRsCtW
0 1
FOXO4 (human) DPDFEPQsRPRsCtW S26-p
FOXO4 (mouse) DPDFEPQSRPRSCtW S26
FOXO4 (rat) DPDFEPQSRPRSCTW S26
S30-p
EPQsRPRsCtWPLPR
0 3
FOXO4 (human) EPQsRPRsCtWPLPR S30-p
FOXO4 (mouse) EPQSRPRSCtWPLPR S30
FOXO4 (rat) EPQSRPRSCTWPLPR S30
T32-p
QsRPRsCtWPLPRPE
Upstream
Downstream
6 41
FOXO4 (human)
T32-p
Effects on Modified Protein
  • intracellular localization
Effects on Biological Processes:
  • transcription, inhibited
Kinase, in vitro:
  • Akt1 (human)
Putative in vivo kinases:
  • Akt1 (human)
Treatment
  • Akt-I-1
  • Epo
  • gefitinib
  • insulin
  • LY294002
  • SCF
  • wortmannin
FOXO4 (human) QsRPRsCtWPLPRPE T32-p
FOXO4 (mouse) QSRPRSCtWPLPRPD T32-p
FOXO4 (rat) QSRPRSCTWPLPRPE T32
S111-p
QSYAELIsQAIESAP
0 1
FOXO4 (human) QSYAELIsQAIESAP S111-p
FOXO4 (mouse) QSYAELISQAIESAP S111
FOXO4 (rat) QSYAELISQAIESAP S111
K186-ac
MLNPEGGkSGkAPRR
Upstream
Downstream
2 0
Effects on Modified Protein
  • activity, inhibited
Effects on Biological Processes:
  • transcription, inhibited
Treatment
  • trichostatin_A
FOXO4 (human) MLNPEGGkSGkAPRR K186-ac
FOXO4 (mouse) MLNPDGGkGGkAPRR K186-ac
FOXO4 (rat) MLNPDGGKGGKAPRR K186
K189-ac
PEGGkSGkAPRRRAA
Upstream
Downstream
2 1
Effects on Modified Protein
  • activity, inhibited
Effects on Biological Processes:
  • transcription, inhibited
Regulatory protein:
  • SIRT1 (human)
Treatment
  • resveratrol
  • trichostatin_A
FOXO4 (human) PEGGkSGkAPRRRAA K189-ac
FOXO4 (mouse) PDGGkGGkAPRRRAA K189-ac
FOXO4 (rat) PDGGKGGKAPRRRAA K189
S197-p
APRRRAAsMDsSSKL
Upstream
Downstream
14 10
FOXO4 (human)
S197-p
FOXO4 (mouse)
S197-p
Effects on Modified Protein
  • intracellular localization
Effects on Biological Processes:
  • apoptosis, altered
  • transcription, inhibited
Kinase, in vitro:
  • Akt1 (human)
Putative in vivo kinases:
  • Akt1 (human)
Regulatory protein:
  • DNAPK (human)
  • LKB1 (human)
Treatment
  • adriamycin
  • Akt-I-1
  • EGF
  • HGF
  • insulin
  • IQA
  • leptomycin_B
  • LY294002
  • PDGF
  • siRNA
  • TBB
  • wortmannin
FOXO4 (human) APRRRAAsMDsSSKL S197-p
FOXO4 (mouse) APRRRAAsMDSSSKL S197-p
FOXO4 (rat) APRRRAASMDSSSKL S197
S200-p
RRAAsMDsSSKLLRG
0 1
FOXO4 (human) RRAAsMDsSSKLLRG S200-p
FOXO4 (mouse) RRAAsMDSSSKLLRG S200
FOXO4 (rat) RRAASMDSSSKLLRG S200
T227-p
PAPPEGAtPTsPVGH
Upstream
Downstream
1 2
Effects on Biological Processes:
  • carcinogenesis, altered
  • transcription, altered
Kinase, in vitro:
  • JNK1 (human)
Putative in vivo kinases:
  • JNK1 (human)
Regulatory protein:
  • BRAF (human)
Treatment
  • anisomycin
  • EGF
  • H2O2
  • phorbol_ester
  • SP600125
  • U0126
FOXO4 (human) PAPPEGAtPTsPVGH T227-p
FOXO4 (mouse) PAPPEGATPRsPLGH T227
FOXO4 (rat) PAPPEGATPRsPLGH T227
S230-p
PEGAtPTsPVGHFAK
Upstream
Downstream
1 13
Effects on Biological Processes:
  • carcinogenesis, altered
  • transcription, altered
Kinase, in vitro:
  • JNK1 (human)
Regulatory protein:
  • BRAF (human)
FOXO4 (human) PEGAtPTsPVGHFAK S230-p
FOXO4 (mouse) PEGATPRsPLGHFAK S230-p
FOXO4 (rat) PEGATPRsPLGHFAK S230-p
S241-p
HFAKWSGsPCsRNRE
0 2
FOXO4 (human) HFAKWSGsPCsRNRE S241-p
FOXO4 (mouse) HFAKWSSSPCPRNRE S241
FOXO4 (rat) HFAKWSSSPCPRNRE S241
S244-p
KWSGsPCsRNREEAD
0 1
FOXO4 (human) KWSGsPCsRNREEAD S244-p
FOXO4 (mouse) KWSSSPCPRNREEAD P244
FOXO4 (rat) KWSSSPCPRNREEAD P244
S261-p
TTFRPRSssNAsSVs
0 7
FOXO4 (human) TTFRPRSssNAsSVs S261-p
FOXO4 (mouse) TTFRPRSSSNASTVS S261
FOXO4 (rat) TTFRPRSSSNASTVS S261
S262-p
TFRPRSssNAsSVsT
Upstream
Downstream
5 2
Effects on Modified Protein
  • intracellular localization
Effects on Biological Processes:
  • transcription, inhibited
Kinase, in vitro:
  • Akt1 (human)
Putative in vivo kinases:
  • Akt1 (human)
Treatment
  • EGF
  • insulin
  • leptomycin_B
  • LY294002
  • PDGF
  • wortmannin
FOXO4 (human) TFRPRSssNAsSVsT S262-p
FOXO4 (mouse) TFRPRSSSNASTVST S262
FOXO4 (rat) TFRPRSSSNASTVST S262
S265-p
PRSssNAsSVsTRLs
Upstream
Downstream
1 0
Effects on Modified Protein
  • phosphorylation
  • protein degradation
Kinase, in vitro:
  • CK1A (human)
Putative in vivo kinases:
  • CK1A (human)
FOXO4 (human) PRSssNAsSVsTRLs S265-p
FOXO4 (mouse) PRSSSNASTVSTRLS S265
FOXO4 (rat) PRSSSNASTVSTRLS S265
S268-p
ssNAsSVsTRLsPLR
Upstream
Downstream
1 0
Effects on Modified Protein
  • phosphorylation
  • protein degradation
Kinase, in vitro:
  • CK1A (human)
Putative in vivo kinases:
  • CK1A (human)
FOXO4 (human) ssNAsSVsTRLsPLR S268-p
FOXO4 (mouse) SSNASTVSTRLSPMR S268
FOXO4 (rat) SSNASTVSTRLSPMR S268
S272-p
sSVsTRLsPLRPEsE
0 2
FOXO4 (human) sSVsTRLsPLRPEsE S272-p
FOXO4 (mouse) STVSTRLSPMRPESE S272
FOXO4 (rat) STVSTRLSPMRPESE S272
S278-p
LsPLRPEsEVLAEEI
0 1
FOXO4 (human) LsPLRPEsEVLAEEI S278-p
FOXO4 (mouse) LSPMRPESEVLAEEE S278
FOXO4 (rat) LSPMRPESEVLAEEE S278
S288-p
LAEEIPAsVSSyAGG
0 1
FOXO4 (human) LAEEIPAsVSSyAGG S288-p
FOXO4 (mouse) AEEEMPASASSYAGG S289
FOXO4 (rat) AEEEMPASASSYAGG S289
Y292-p
IPAsVSSyAGGVPPT
0 1
FOXO4 (human) IPAsVSSyAGGVPPT Y292-p
FOXO4 (mouse) MPASASSYAGGVPPT Y293
FOXO4 (rat) MPASASSYAGGVPPT Y293
K407-ac
GGLPSSSkLATGVGL
Upstream
Downstream
2 0
Effects on Modified Protein
  • activity, inhibited
Effects on Biological Processes:
  • transcription, inhibited
Treatment
  • trichostatin_A
FOXO4 (human) GGLPSSSkLATGVGL K407-ac
FOXO4 (mouse) GGMPSSSkLGTGVSL K408-ac
FOXO4 (rat) GGMPSSSKLATGVSL K408
T451-p
PIPKALGtPVLtPPt
Upstream
Downstream
3 3
Effects on Modified Protein
  • intracellular localization
Effects on Biological Processes:
  • cell cycle regulation
  • transcription, induced
Kinase, in vitro:
  • JNK1 (human)
Putative in vivo kinases:
  • JNK1 (human)
  • JNK2 (human)
Regulatory protein:
  • BRAF (human)
Treatment
  • H2O2
FOXO4 (human) PIPKALGtPVLtPPt T451-p
FOXO4 (mouse) PIPKVLGtPVLAsPt T452-p
FOXO4 (rat) PIPKVLGTPVLASPT T452
T455-p
ALGtPVLtPPtEAAS
Upstream
Downstream
3 2
Effects on Modified Protein
  • intracellular localization
Effects on Biological Processes:
  • cell cycle regulation
  • transcription, induced
Kinase, in vitro:
  • JNK1 (human)
Putative in vivo kinases:
  • JNK1 (human)
  • JNK2 (human)
Regulatory protein:
  • BRAF (human)
  • RALA (human)
Treatment
  • H2O2
  • LY294002
  • PD98059
  • SB203580
FOXO4 (human) ALGtPVLtPPtEAAS T455-p
FOXO4 (mouse) VLGtPVLAsPtEDSS A456
FOXO4 (rat) VLGTPVLASPTEDFS A456
P456
LGtPVLtPPtEAASQ
0 1
FOXO4 (human) LGtPVLtPPtEAASQ P456
FOXO4 (mouse) LGtPVLAsPtEDSSH S457-p
FOXO4 (rat) LGTPVLASPTEDFSH S457
T458-p
tPVLtPPtEAASQDR
0 2
FOXO4 (human) tPVLtPPtEAASQDR T458-p
FOXO4 (mouse) tPVLAsPtEDSSHDR T459-p
FOXO4 (rat) TPVLASPTEDFSHDR T459