Other Species / Isoforms
  FANCD2 (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

 HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
S8-p
MVSKRRLsKSEDKEs
Upstream
0 2
Treatment
  • ischemia
FANCD2 (human) MVSKRRLsKSEDKEs S8-p
FANCD2 iso1 (human) MVSKRRLSKSEDKES S8
FANCD2 iso3 (human) MVSKRRLSKSEDKES S8
FANCD2 (mouse) MISKRRRLDsEDKEN L8
FANCD2 (rat) MVSKRSRLDFEDKET L8
FANCD2 (chicken) MVSKRKLSKIDAAEE S8
S10
SKRRLsKSEDKEsLT
0 39
FANCD2 (human) SKRRLsKSEDKEsLT S10
FANCD2 iso1 (human) SKRRLSKSEDKESLT S10
FANCD2 iso3 (human) SKRRLSKSEDKESLT S10
FANCD2 (mouse) SKRRRLDsEDKENLt S10-p
FANCD2 (rat) SKRSRLDFEDKETLA F10
FANCD2 (chicken) SKRKLSKIDAAEESS I10
S15-p
sKSEDKEsLTEDASK
0 2
FANCD2 (human) sKSEDKEsLTEDASK S15-p
FANCD2 iso1 (human) SKSEDKESLTEDASK S15
FANCD2 iso3 (human) SKSEDKESLTEDASK S15
FANCD2 (mouse) LDsEDKENLtEDASK N15
FANCD2 (rat) LDFEDKETLAEDASK T15
FANCD2 (chicken) gap -
T17
SEDKEsLTEDASKTR
0 1
FANCD2 (human) SEDKEsLTEDASKTR T17
FANCD2 iso1 (human) SEDKESLTEDASKTR T17
FANCD2 iso3 (human) SEDKESLTEDASKTR T17
FANCD2 (mouse) sEDKENLtEDASKTM T17-p
FANCD2 (rat) FEDKETLAEDASKIM A17
FANCD2 (chicken) KLSKIDAAEESSKTD A13
K33-ub
QPLSKKTkkSHIANE
0 1
FANCD2 (human) QPLSKKTkkSHIANE K33-ub
FANCD2 iso1 (human) QPLSKKTKKSHIANE K33
FANCD2 iso3 (human) QPLSKKTKKSHIANE K33
FANCD2 (mouse) MPLSKLAKKSHNSHE K31
FANCD2 (rat) QPLSKLAKKSCGSHE K33
FANCD2 (chicken) QSRCPETKRSRISDK K29
K34-ub
PLSKKTkkSHIANEV
0 1
FANCD2 (human) PLSKKTkkSHIANEV K34-ub
FANCD2 iso1 (human) PLSKKTKKSHIANEV K34
FANCD2 iso3 (human) PLSKKTKKSHIANEV K34
FANCD2 (mouse) PLSKLAKKSHNSHEV K32
FANCD2 (rat) PLSKLAKKSCGSHEV K34
FANCD2 (chicken) SRCPETKRSRISDKR R30
K50-ub
ENDSIFVkLLkISGI
0 1
FANCD2 (human) ENDSIFVkLLkISGI K50-ub
FANCD2 iso1 (human) ENDSIFVKLLKISGI K50
FANCD2 iso3 (human) ENDSIFVKLLKISGI K50
FANCD2 (mouse) ENGSVFVKLLKASGL K48
FANCD2 (rat) ENGSVFVRLLKASGL R50
FANCD2 (chicken) under review -
K53-ub
SIFVkLLkISGIILk
0 3
FANCD2 (human) SIFVkLLkISGIILk K53-ub
FANCD2 iso1 (human) SIFVKLLKISGIILK K53
FANCD2 iso3 (human) SIFVKLLKISGIILK K53
FANCD2 (mouse) SVFVKLLKASGLTLK K51
FANCD2 (rat) SVFVRLLKASGLTLK K53
FANCD2 (chicken) GVFEELLRTSGIILK R55
K60-ub
kISGIILkTGESQNQ
0 3
FANCD2 (human) kISGIILkTGESQNQ K60-ub
FANCD2 iso1 (human) KISGIILKTGESQNQ K60
FANCD2 iso3 (human) KISGIILKTGESQNQ K60
FANCD2 (mouse) KASGLTLKTGENQNQ K58
FANCD2 (rat) KASGLTLKTGDNQNQ K60
FANCD2 (chicken) RTSGIILKVGEGQNE K62
K77-ub
VDQIAFQkkLFQTLR
0 2
FANCD2 (human) VDQIAFQkkLFQTLR K77-ub
FANCD2 iso1 (human) VDQIAFQKKLFQTLR K77
FANCD2 iso3 (human) VDQIAFQKKLFQTLR K77
FANCD2 (mouse) VDQVIFQRKLFQALR R75
FANCD2 (rat) VDQIIFQRKLFQALR R77
FANCD2 (chicken) VDQTAFQKKLRVALE K79
K78-ub
DQIAFQkkLFQTLRR
0 2
FANCD2 (human) DQIAFQkkLFQTLRR K78-ub
FANCD2 iso1 (human) DQIAFQKKLFQTLRR K78
FANCD2 iso3 (human) DQIAFQKKLFQTLRR K78
FANCD2 (mouse) DQVIFQRKLFQALRK K76
FANCD2 (rat) DQIIFQRKLFQALRK K78
FANCD2 (chicken) DQTAFQKKLRVALEK K80
K133-ub
SMGASYSkSLIKLLL
0 4
FANCD2 (human) SMGASYSkSLIKLLL K133-ub
FANCD2 iso1 (human) SMGASYSKSLIKLLL K133
FANCD2 iso3 (human) SMGASYSKSLIKLLL K133
FANCD2 (mouse) SMGTFYSKSLIKLLL K131
FANCD2 (rat) SMGTFYSKSLIKLLL K133
FANCD2 (chicken) TLVHSYCESLIKLLL E136
K156-ub
IIKTLFEkLPEYFFE
0 3
FANCD2 (human) IIKTLFEkLPEYFFE K156-ub
FANCD2 iso1 (human) IIKTLFEKLPEYFFE K156
FANCD2 iso3 (human) IIKTLFEKLPEYFFE K156
FANCD2 (mouse) IIKMLFEKVPQFLFE K154
FANCD2 (rat) IIKMLFEKVPQFLFE K156
FANCD2 (chicken) VVTLLLEKIPEFFFD K159
K165-ub
PEYFFENkNsDEINI
0 5
FANCD2 (human) PEYFFENkNsDEINI K165-ub
FANCD2 iso1 (human) PEYFFENKNSDEINI K165
FANCD2 iso3 (human) PEYFFENKNSDEINI K165
FANCD2 (mouse) PQFLFESENRDGINM E163
FANCD2 (rat) PQFLFESESRDGISM E165
FANCD2 (chicken) PEFFFDVVGTFGTNF V168
S167-p
YFFENkNsDEINIPR
0 1
FANCD2 (human) YFFENkNsDEINIPR S167-p
FANCD2 iso1 (human) YFFENKNSDEINIPR S167
FANCD2 iso3 (human) YFFENKNSDEINIPR S167
FANCD2 (mouse) FLFESENRDGINMAR R165
FANCD2 (rat) FLFESESRDGISMPR R167
FANCD2 (chicken) FFFDVVGTFGTNFPR T170
S178-p
NIPRLIVsQLkWLDR
0 1
FANCD2 (human) NIPRLIVsQLkWLDR S178-p
FANCD2 iso1 (human) NIPRLIVSQLKWLDR S178
FANCD2 iso3 (human) NIPRLIVSQLKWLDR S178
FANCD2 (mouse) NMARLIINQLKWLDR N176
FANCD2 (rat) SMPRLIISQLKWLDR S178
FANCD2 (chicken) NFPRLIVNQFKWLDG N181
K181-ub
RLIVsQLkWLDRVVD
0 4
FANCD2 (human) RLIVsQLkWLDRVVD K181-ub
FANCD2 iso1 (human) RLIVSQLKWLDRVVD K181
FANCD2 iso3 (human) RLIVSQLKWLDRVVD K181
FANCD2 (mouse) RLIINQLKWLDRIVD K179
FANCD2 (rat) RLIISQLKWLDRIVD K181
FANCD2 (chicken) RLIVNQFKWLDGLLD K184
K190-ub
LDRVVDGkDLTTKIM
0 1
FANCD2 (human) LDRVVDGkDLTTKIM K190-ub
FANCD2 iso1 (human) LDRVVDGKDLTTKIM K190
FANCD2 iso3 (human) LDRVVDGKDLTTKIM K190
FANCD2 (mouse) LDRIVDGKDLTAQMM K188
FANCD2 (rat) LDRIVDSKDLTTQMM K190
FANCD2 (chicken) under review -
S201-p
TKIMQLIsIAPENLQ
0 1
FANCD2 (human) TKIMQLIsIAPENLQ S201-p
FANCD2 iso1 (human) TKIMQLISIAPENLQ S201
FANCD2 iso3 (human) TKIMQLISIAPENLQ S201
FANCD2 (mouse) AQMMQLISVAPVNLQ S199
FANCD2 (rat) TQMMQLISVAPVNLQ S201
FANCD2 (chicken) KKLMQMLSVSPVPIQ S204
S222-p
LPEILGDsQHADVGK
Upstream
Downstream
3 2
Effects on Biological Processes:
  • cell cycle regulation
Kinase, in vitro:
  • ATM (human)
Putative in vivo kinases:
  • ATM (human)
Treatment
  • ionizing_radiation
  • mitomycin_C
FANCD2 (human) LPEILGDsQHADVGK S222-p
FANCD2 iso1 (human) LPEILGDSQHADVGK S222
FANCD2 iso3 (human) LPEILGDSQHADVGK S222
FANCD2 (mouse) LPEILGDSQHANVGK S220
FANCD2 (rat) LPEILGDSQHANVGK S222
FANCD2 (chicken) LPEILEDSQQNEVAR S225
K261-ub
LDPNFLLkVRQLVMD
0 2
FANCD2 (human) LDPNFLLkVRQLVMD K261-ub
FANCD2 iso1 (human) LDPNFLLKVRQLVMD K261
FANCD2 iso3 (human) LDPNFLLKVRQLVMD K261
FANCD2 (mouse) LDPNFLSKIRQLVMG K259
FANCD2 (rat) LDPNFLSEIRQLVMG E261
FANCD2 (chicken) LDAELLAEVRQSAMT E264
S319-p
LPSRLQAsQVkLKSK
0 13
FANCD2 (human) LPSRLQAsQVkLKSK S319-p
FANCD2 iso1 (human) LPSRLQASQVKLKSK S319
FANCD2 iso3 (human) LPSRLQASQVKLKSK S319
FANCD2 (mouse) LPSRIQASQSKLKSK S317
FANCD2 (rat) LPSRIQASQSKLKSK S319
FANCD2 (chicken) LPLQLLGSQRKLKSQ S322
K322-ub
RLQAsQVkLKSKGRA
0 3
FANCD2 (human) RLQAsQVkLKSKGRA K322-ub
FANCD2 iso1 (human) RLQASQVKLKSKGRA K322
FANCD2 iso3 (human) RLQASQVKLKSKGRA K322
FANCD2 (mouse) RIQASQSKLKSKGLA K320
FANCD2 (rat) RIQASQSKLKSKGLA K322
FANCD2 (chicken) QLLGSQRKLKSQAQA K325
S331-p
KSKGRASsSGNQESS
Upstream
Downstream
1 1
Effects on Modified Protein
  • molecular association, regulation
  • ubiquitination
Kinase, in vitro:
  • Chk1 (human)
Putative in vivo kinases:
  • Chk1 (human)
Treatment
  • mitomycin_C
  • SB218078
FANCD2 (human) KSKGRASsSGNQESS S331-p
FANCD2 iso1 (human) KSKGRASSSGNQESS S331
FANCD2 iso3 (human) KSKGRASSSGNQESS S331
FANCD2 (mouse) KSKGLASSSGNQENS S329
FANCD2 (rat) KSKGLASSSGNQENS S331
FANCD2 (chicken) KSQAQASSSMSQVTT S334
K358-ub
KSAIRYEkTISEAWI
0 2
FANCD2 (human) KSAIRYEkTISEAWI K358-ub
FANCD2 iso1 (human) KSAIRYEKTISEAWI K358
FANCD2 iso3 (human) KSAIRYEKTISEAWI K358
FANCD2 (mouse) KSAIRYEKTISEAWF K356
FANCD2 (rat) KSAIRYEKTISEAWI K358
FANCD2 (chicken) KQAVRFQKDVSEAWI K361
K366-ub
TISEAWIkAIENTAS
0 1
FANCD2 (human) TISEAWIkAIENTAS K366-ub
FANCD2 iso1 (human) TISEAWIKAIENTAS K366
FANCD2 iso3 (human) TISEAWIKAIENTAS K366
FANCD2 (mouse) TISEAWFKAIERIES K364
FANCD2 (rat) TISEAWIKAIERIQS K366
FANCD2 (chicken) DVSEAWIKAIENSTS K369
Y458-p
ISFGSLLyKYAFKFF
0 1
FANCD2 (human) ISFGSLLyKYAFKFF Y458-p
FANCD2 iso1 (human) ISFGSLLYKYAFKFF Y458
FANCD2 iso3 (human) ISFGSLLYKYAFKFF Y458
FANCD2 (mouse) ILFGSLLYKYAFKFF Y456
FANCD2 (rat) ILFGSLLCKYAFKFF C458
FANCD2 (chicken) VSFGSCMYKQAFAVF Y461
S483
ALVTHICSGNEAEVD
0 1
FANCD2 (human) ALVTHICSGNEAEVD S483
FANCD2 iso1 (human) ALVTHICSGNEAEVD S483
FANCD2 iso3 (human) ALVTHICSGNEAEVD S483
FANCD2 (mouse) ALVTHVCsGTEAEVD S481-p
FANCD2 (rat) ALVTHVCSGNEAEVD S483
FANCD2 (chicken) ALVTHVCSGNETELD S486
K561-ub
DMHLVIRkQLSSTVF
Upstream
10 63
Treatment
  • MG132
  • vorinostat
FANCD2 (human) DMHLVIRkQLSSTVF K561-ub
FANCD2 iso1 (human) DMHLVIRKQLSSTVF K561
FANCD2 iso3 (human) DMHLVIRKQLSSTVF K561
FANCD2 (mouse) DMHLVIRkQLSSTVF K559-ub
FANCD2 (rat) DMHLVIRKQLSSTVF K561
FANCD2 (chicken) DMHMVIRkWLSSSVP K563-ub
K569-ub
QLSSTVFkYKLIGII
0 1
FANCD2 (human) QLSSTVFkYKLIGII K569-ub
FANCD2 iso1 (human) QLSSTVFKYKLIGII K569
FANCD2 iso3 (human) QLSSTVFKYKLIGII K569
FANCD2 (mouse) QLSSTVFKYKLIGII K567
FANCD2 (rat) QLSSTVFKYKLIGII K569
FANCD2 (chicken) under review -
S590-p
GIMAADRsEsPsLtQ
0 1
FANCD2 (human) GIMAADRsEsPsLtQ S590-p
FANCD2 iso1 (human) GIMAADRSESPSLTQ S590
FANCD2 iso3 (human) GIMAADRSESPSLTQ S590
FANCD2 (mouse) GIMAEDRSVPSNSSQ S588
FANCD2 (rat) GIMAEDRTMPSNSTQ T590
FANCD2 (chicken) GSVALKRNEADGGLL N592
S592-p
MAADRsEsPsLtQER
Upstream
0 27
Regulatory protein:
  • PLK1 (human)
Treatment
  • BI2536
  • MLN8054
  • UV
FANCD2 (human) MAADRsEsPsLtQER S592-p
FANCD2 iso1 (human) MAADRSESPSLTQER S592
FANCD2 iso3 (human) MAADRSESPSLTQER S592
FANCD2 (mouse) MAEDRSVPSNSSQRS P590
FANCD2 (rat) MAEDRTMPSNSTQRS P592
FANCD2 (chicken) VALKRNEADGGLLER A594
S594-p
ADRsEsPsLtQERAN
0 1
FANCD2 (human) ADRsEsPsLtQERAN S594-p
FANCD2 iso1 (human) ADRSESPSLTQERAN S594
FANCD2 iso3 (human) ADRSESPSLTQERAN S594
FANCD2 (mouse) EDRSVPSNSSQRSAN N592
FANCD2 (rat) EDRTMPSNSTQRSAS N594
FANCD2 (chicken) LKRNEADGGLLERPE G596
T596-p
RsEsPsLtQERANLS
Upstream
1 11
Kinase, in vitro:
  • ATR (human)
Treatment
  • UV
FANCD2 (human) RsEsPsLtQERANLS T596-p
FANCD2 iso1 (human) RSESPSLTQERANLS T596
FANCD2 iso3 (human) RSESPSLTQERANLS T596
FANCD2 (mouse) RSVPSNSSQRSANVS S594
FANCD2 (rat) RTMPSNSTQRSASVS T596
FANCD2 (chicken) RNEADGGLLERPELS L598
T608-p
NLSDEQCtQVTSLLQ
Upstream
1 0
Kinase, in vitro:
  • ATR (human)
FANCD2 (human) NLSDEQCtQVTSLLQ T608-p
FANCD2 iso1 (human) NLSDEQCTQVTSLLQ T608
FANCD2 iso3 (human) NLSDEQCTQVTSLLQ T608
FANCD2 (mouse) NVSSEQRTQVTSLLQ T606
FANCD2 (rat) SVSSEQHTQVTSLLQ T608
FANCD2 (chicken) ELSIECDGQLSTLLD G610
Y684-p
PFPVKALyGLEEYDt
0 1
FANCD2 (human) PFPVKALyGLEEYDt Y684-p
FANCD2 iso1 (human) PFPVKALYGLEEYDT Y684
FANCD2 iso3 (human) PFPVKALYGLEEYDT Y684
FANCD2 (mouse) PFPVKALYGLEEYST Y682
FANCD2 (rat) PFPVKALYGLEECNT Y684
FANCD2 (chicken) LFPVKSLYNLDEDET Y688
T691-p
yGLEEYDtQDGIAIN
Upstream
Downstream
1 4
Effects on Modified Protein
  • activity, induced
Effects on Biological Processes:
  • cell cycle regulation
Kinase, in vitro:
  • ATR (human)
Putative in vivo kinases:
  • ATM (human)
  • ATR (human)
Treatment
  • hydroxyurea
  • ionizing_radiation
  • UV
FANCD2 (human) yGLEEYDtQDGIAIN T691-p
FANCD2 iso1 (human) YGLEEYDTQDGIAIN T691
FANCD2 iso3 (human) YGLEEYDTQDGIAIN T691
FANCD2 (mouse) YGLEEYSTQDGIVIN T689
FANCD2 (rat) YGLEECNTQDGIVIN T691
FANCD2 (chicken) YNLDEDETQGAIAIN T695
S717-p
KDGGPVTsQESGQkL
Upstream
Downstream
1 8
Effects on Modified Protein
  • activity, induced
Effects on Biological Processes:
  • cell cycle regulation
Kinase, in vitro:
  • ATR (human)
Putative in vivo kinases:
  • ATM (human)
  • ATR (human)
Treatment
  • ionizing_radiation
  • UV
FANCD2 (human) KDGGPVTsQESGQkL S717-p
FANCD2 iso1 (human) KDGGPVTSQESGQKL S717
FANCD2 iso3 (human) KDGGPVTSQESGQKL S717
FANCD2 (mouse) KDASRATSQESSQRS S714
FANCD2 (rat) KDVSQVTSQESSQKS S716
FANCD2 (chicken) RVADEMSNSRKRVVS N721
K723-ub
TsQESGQkLVSPLCL
0 3
FANCD2 (human) TsQESGQkLVSPLCL K723-ub
FANCD2 iso1 (human) TSQESGQKLVSPLCL K723
FANCD2 iso3 (human) TSQESGQKLVSPLCL K723
FANCD2 (mouse) TSQESSQRSMSSLCL R720
FANCD2 (rat) TSQESSQKSMSPLCL K722
FANCD2 (chicken) EMSNSRKRVVSPICL R725
K878-ub
KQKTDGSkTSSsDtL
0 1
FANCD2 (human) KQKTDGSkTSSsDtL K878-ub
FANCD2 iso1 (human) KQKTDGSKTSSSDTL K878
FANCD2 iso3 (human) KQKTDGSKTSSSDTL K878
FANCD2 (mouse) KQKADSNKASCSDTL K876
FANCD2 (rat) KQKADSSTASCTDTL T878
FANCD2 (chicken) KRKSDSSKACSAERT K876
S882-p
DGSkTSSsDtLsEEk
Upstream
Downstream
1 1
Effects on Modified Protein
  • activity, inhibited
  • intracellular localization
  • molecular association, regulation
  • ubiquitination
Effects on Biological Processes:
  • DNA repair, inhibited
  • cell cycle regulation
  • signaling pathway regulation
Putative in vivo kinases:
  • CK2A1 (human)
Treatment
  • silmitasertib
FANCD2 (human) DGSkTSSsDtLsEEk S882-p
FANCD2 iso1 (human) under review -
FANCD2 iso3 (human) under review -
FANCD2 (mouse) under review -
FANCD2 (rat) under review -
FANCD2 (chicken) under review -
T884-p
SkTSSsDtLsEEkNs
Upstream
Downstream
1 1
Effects on Modified Protein
  • activity, inhibited
  • intracellular localization
  • molecular association, regulation
  • ubiquitination
Effects on Biological Processes:
  • DNA repair, inhibited
  • cell cycle regulation
  • signaling pathway regulation
Putative in vivo kinases:
  • CK2A1 (human)
Treatment
  • silmitasertib
FANCD2 (human) SkTSSsDtLsEEkNs T884-p
FANCD2 iso1 (human) under review -
FANCD2 iso3 (human) under review -
FANCD2 (mouse) under review -
FANCD2 (rat) under review -
FANCD2 (chicken) under review -
S886-p
TSSsDtLsEEkNsEC
Upstream
Downstream
1 3
Effects on Modified Protein
  • activity, inhibited
  • intracellular localization
  • molecular association, regulation
  • ubiquitination
Effects on Biological Processes:
  • DNA repair, inhibited
  • cell cycle regulation
  • signaling pathway regulation
Kinase, in vitro:
  • CK2A1 (human)
Putative in vivo kinases:
  • CK2A1 (human)
Treatment
  • silmitasertib
FANCD2 (human) TSSsDtLsEEkNsEC S886-p
FANCD2 iso1 (human) TSSSDTLSEEKNSEC S886
FANCD2 iso3 (human) TSSSDTLSEEKNSEC S886
FANCD2 (mouse) ASCSDTLLTEDTSEC L884
FANCD2 (rat) ASCTDTLLTEDTSEC L886
FANCD2 (chicken) ACSAERTQADESSDG Q884
K889-ub
sDtLsEEkNsECDPt
0 1
FANCD2 (human) sDtLsEEkNsECDPt K889-ub
FANCD2 iso1 (human) SDTLSEEKNSECDPT K889
FANCD2 iso3 (human) SDTLSEEKNSECDPT K889
FANCD2 (mouse) SDTLLTEDTSECDMA D887
FANCD2 (rat) TDTLLTEDTSECDVA D889
FANCD2 (chicken) AERTQADESSDGNQP E887
S891-p
tLsEEkNsECDPtPs
Upstream
Downstream
1 1
Effects on Modified Protein
  • activity, inhibited
  • intracellular localization
  • molecular association, regulation
  • ubiquitination
Effects on Biological Processes:
  • DNA repair, inhibited
  • cell cycle regulation
  • signaling pathway regulation
Putative in vivo kinases:
  • CK2A1 (human)
Treatment
  • silmitasertib
FANCD2 (human) tLsEEkNsECDPtPs S891-p
FANCD2 iso1 (human) under review -
FANCD2 iso3 (human) under review -
FANCD2 (mouse) under review -
FANCD2 (rat) under review -
FANCD2 (chicken) under review -
T896-p
kNsECDPtPsHRGQL
Upstream
Downstream
1 4
Effects on Modified Protein
  • activity, inhibited
  • intracellular localization
  • molecular association, regulation
  • ubiquitination
Effects on Biological Processes:
  • DNA repair, inhibited
  • cell cycle regulation
  • signaling pathway regulation
Kinase, in vitro:
  • CK2A1 (human)
Putative in vivo kinases:
  • CK2A1 (human)
Treatment
  • silmitasertib
FANCD2 (human) kNsECDPtPsHRGQL T896-p
FANCD2 iso1 (human) KNSECDPTPSHRGQL T896
FANCD2 iso3 (human) KNSECDPTPSHRGQL T896
FANCD2 (mouse) DTSECDMAPSGRSHV A894
FANCD2 (rat) DTSECDVAPSGKSQV A896
FANCD2 (chicken) ESSDGNQPDTELSEL P894
S898-p
sECDPtPsHRGQLNk
Upstream
Downstream
1 1
Effects on Modified Protein
  • activity, inhibited
  • intracellular localization
  • molecular association, regulation
  • ubiquitination
Effects on Biological Processes:
  • DNA repair, inhibited
  • cell cycle regulation
  • signaling pathway regulation
Putative in vivo kinases:
  • CK2A1 (human)
Treatment
  • silmitasertib
FANCD2 (human) sECDPtPsHRGQLNk S898-p
FANCD2 iso1 (human) under review -
FANCD2 iso3 (human) under review -
FANCD2 (mouse) under review -
FANCD2 (rat) under review -
FANCD2 (chicken) under review -
K905-ub
sHRGQLNkEFTGKEE
0 3
FANCD2 (human) sHRGQLNkEFTGKEE K905-ub
FANCD2 iso1 (human) SHRGQLNKEFTGKEE K905
FANCD2 iso3 (human) SHRGQLNKEFTGKEE K905
FANCD2 (mouse) SGRSHVDKESTGKEG K903
FANCD2 (rat) SGKSQVDKESTGKEG K905
FANCD2 (chicken) TELSELEKSATEKET K903
K913-ub
EFTGKEEkTSLLLHN
0 1
FANCD2 (human) EFTGKEEkTSLLLHN K913-ub
FANCD2 iso1 (human) EFTGKEEKTSLLLHN K913
FANCD2 iso3 (human) EFTGKEEKTSLLLHN K913
FANCD2 (mouse) ESTGKEGKTFVSLQN K911
FANCD2 (rat) ESTGKEGKTFVSLQN K913
FANCD2 (chicken) ATEKETGNPLAQLQS N912
S978-p
DLSQKLEsMLtPPIA
0 1
FANCD2 (human) DLSQKLEsMLtPPIA S978-p
FANCD2 iso1 (human) DLSQKLESMLTPPIA S978
FANCD2 iso3 (human) DLSQKLESMLTPPIA S978
FANCD2 (mouse) DLSQKLENMLtAPFA N976
FANCD2 (rat) DLSQKLENRLTPSFT N978
FANCD2 (chicken) DMCWKLEHVLTPGST H977
T981-p
QKLEsMLtPPIARRV
0 2
FANCD2 (human) QKLEsMLtPPIARRV T981-p
FANCD2 iso1 (human) QKLESMLTPPIARRV T981
FANCD2 iso3 (human) QKLESMLTPPIARRV T981
FANCD2 (mouse) QKLENMLtAPFAKRI T979-p
FANCD2 (rat) QKLENRLTPSFTKRV T981
FANCD2 (chicken) WKLEHVLTPGSTRRV T980
K992-m1
ARRVPFLkNKGSRNI
0 1
FANCD2 (human) ARRVPFLkNKGSRNI K992-m1
FANCD2 iso1 (human) ARRVPFLKNKGSRNI K992
FANCD2 iso3 (human) ARRVPFLKNKGSRNI K992
FANCD2 (mouse) AKRICCFKNKGRQNI K990
FANCD2 (rat) TKRVCFFKNKGSRNI K992
FANCD2 (chicken) TRRVPFLKERGNKDV K991
K992-ub
ARRVPFLkNKGSRNI
0 1
FANCD2 (human) ARRVPFLkNKGSRNI K992-ub
FANCD2 iso1 (human) ARRVPFLKNKGSRNI K992
FANCD2 iso3 (human) ARRVPFLKNKGSRNI K992
FANCD2 (mouse) under review -
FANCD2 (rat) TKRVCFFKNKGSRNI K992
FANCD2 (chicken) under review -
K1154-ub
ASAQNKEkIAsLARQ
0 2
FANCD2 (human) ASAQNKEkIAsLARQ K1154-ub
FANCD2 iso1 (human) ASAQNKEKIASLARQ K1154
FANCD2 iso3 (human) ASAQNKEKIASLARQ K1154
FANCD2 (mouse) VPNQKKEKLASLAKQ K1152
FANCD2 (rat) VPTQKKEKLASLAKQ K1154
FANCD2 (chicken) MTGWKREKMASLAKQ K1152
S1157-p
QNKEkIAsLARQFLC
0 1
FANCD2 (human) QNKEkIAsLARQFLC S1157-p
FANCD2 iso1 (human) QNKEKIASLARQFLC S1157
FANCD2 iso3 (human) QNKEKIASLARQFLC S1157
FANCD2 (mouse) QKKEKLASLAKQLLC S1155
FANCD2 (rat) QKKEKLASLAKQLLC S1157
FANCD2 (chicken) WKREKMASLAKQFLC S1155
K1172-ac
RVWPSGDkEKSNISN
0 1
FANCD2 (human) RVWPSGDkEKSNISN K1172-ac
FANCD2 iso1 (human) RVWPSGDKEKSNISN K1172
FANCD2 iso3 (human) RVWPSGDKEKSNISN K1172
FANCD2 (mouse) RAWPHGEKEKNPTFN K1170
FANCD2 (rat) RAWPHGDKEKNPTFN K1172
FANCD2 (chicken) WMKPGGDREKGSHFN R1172
K1198-ac
EHTESILkAIEEIAG
0 1
FANCD2 (human) EHTESILkAIEEIAG K1198-ac
FANCD2 iso1 (human) EHTESILKAIEEIAG K1198
FANCD2 iso3 (human) EHTESILKAIEEIAG K1198
FANCD2 (mouse) EHTDNVLKAIEEITG K1196
FANCD2 (rat) EHTDNVLKAIEEITG K1198
FANCD2 (chicken) EHTDNILKAIEEISS K1198
S1214-p
GVPELINsPkDASSS
0 1
FANCD2 (human) GVPELINsPkDASSS S1214-p
FANCD2 iso1 (human) GVPELINSPKDASSS S1214
FANCD2 iso3 (human) GVPELINSPKDASSS S1214
FANCD2 (mouse) GVPELVSAPKDAASS A1212
FANCD2 (rat) GVPELVNAPKDASSS A1214
FANCD2 (chicken) GVPELINSAKDGCSS S1214
K1216-ub
PELINsPkDASSSTF
0 2
FANCD2 (human) PELINsPkDASSSTF K1216-ub
FANCD2 iso1 (human) PELINSPKDASSSTF K1216
FANCD2 iso3 (human) PELINSPKDASSSTF K1216
FANCD2 (mouse) PELVSAPKDAASSTF K1214
FANCD2 (rat) PELVNAPKDASSSTF K1216
FANCD2 (chicken) PELINSAKDGCSSTY K1216
K1248-ub
ELEKTVKkIEPGtAA
0 2
FANCD2 (human) ELEKTVKkIEPGtAA K1248-ub
FANCD2 iso1 (human) ELEKTVKKIEPGTAA K1248
FANCD2 iso3 (human) gap -
FANCD2 (mouse) ELEKTVKGLQAGTAA G1246
FANCD2 (rat) ELEKTVKGLQAGTAT G1248
FANCD2 (chicken) QLESSVKSIPAGKPS S1248
T1253-p
VKkIEPGtAADsQQI
0 1
FANCD2 (human) VKkIEPGtAADsQQI T1253-p
FANCD2 iso1 (human) VKKIEPGTAADSQQI T1253
FANCD2 iso3 (human) gap -
FANCD2 (mouse) VKGLQAGTAADSQQV T1251
FANCD2 (rat) VKGLQAGTATDSQQV T1253
FANCD2 (chicken) VKSIPAGKPSDSGEV K1253
S1257-p
EPGtAADsQQIHEEK
Upstream
0 6
Regulatory protein:
  • PRKD1 (human)
FANCD2 (human) EPGtAADsQQIHEEK S1257-p
FANCD2 iso1 (human) EPGTAADSQQIHEEK S1257
FANCD2 iso3 (human) gap -
FANCD2 (mouse) QAGTAADSQQVHEEK S1255
FANCD2 (rat) QAGTATDSQQVHEEK S1257
FANCD2 (chicken) PAGKPSDSGEVQLEK S1257
K1346-ub
HHLCGHSkIHQDTRL
0 3
FANCD2 (human) HHLCGHSkIHQDTRL K1346-ub
FANCD2 iso1 (human) HHLCGHSKIHQDTRL K1346
FANCD2 iso3 (human) gap -
FANCD2 (mouse) HHLCGHSKIRQDTRL K1344
FANCD2 (rat) HHLCGHSKIHQDTRL K1346
FANCD2 (chicken) HHMCGHSKIHQDLGL K1346
K1361-ub
TQHVPLLkktLELLV
0 1
FANCD2 (human) TQHVPLLkktLELLV K1361-ub
FANCD2 iso1 (human) TQHVPLLKKTLELLV K1361
FANCD2 iso3 (human) under review -
FANCD2 (mouse) TKHVPLLKKSLELLV K1359
FANCD2 (rat) TKHVPLLKKSLELLV K1361
FANCD2 (chicken) TNHVPLLKKSLEQFV K1361
K1362-ub
QHVPLLkktLELLVC
0 1
FANCD2 (human) QHVPLLkktLELLVC K1362-ub
FANCD2 iso1 (human) QHVPLLKKTLELLVC K1362
FANCD2 iso3 (human) gap -
FANCD2 (mouse) KHVPLLKKSLELLVC K1360
FANCD2 (rat) KHVPLLKKSLELLVC K1362
FANCD2 (chicken) NHVPLLKKSLEQFVY K1362
T1363-p
HVPLLkktLELLVCR
0 1
FANCD2 (human) HVPLLkktLELLVCR T1363-p
FANCD2 iso1 (human) HVPLLKKTLELLVCR T1363
FANCD2 iso3 (human) gap -
FANCD2 (mouse) HVPLLKKSLELLVCR S1361
FANCD2 (rat) HVPLLKKSLELLVCR S1363
FANCD2 (chicken) HVPLLKKSLEQFVYR S1363
K1372-ub
ELLVCRVkAMLTLNN
0 1
FANCD2 (human) ELLVCRVkAMLTLNN K1372-ub
FANCD2 iso1 (human) ELLVCRVKAMLTLNN K1372
FANCD2 iso3 (human) gap -
FANCD2 (mouse) ELLVCRVKAMLVLNN K1370
FANCD2 (rat) ELLVCRVKAMLVLNN K1372
FANCD2 (chicken) EQFVYRVKAMLAFNH K1372
K1390-ub
AFWLGNLkNRDLQGE
0 4
FANCD2 (human) AFWLGNLkNRDLQGE K1390-ub
FANCD2 iso1 (human) AFWLGNLKNRDLQGE K1390
FANCD2 iso3 (human) gap -
FANCD2 (mouse) AFWLGTLKNRDLQGE K1388
FANCD2 (rat) AFWLGTLKNRDLQGE K1390
FANCD2 (chicken) AFWVGVLKNRDLQGE K1390
S1401-p
LQGEEIKsQNsQEst
0 5
FANCD2 (human) LQGEEIKsQNsQEst S1401-p
FANCD2 iso1 (human) LQGEEIKSQNSQEST S1401
FANCD2 iso3 (human) gap -
FANCD2 (mouse) LQGEEIISQDPsssE S1399
FANCD2 (rat) LQGEEIISQHPSSPE S1401
FANCD2 (chicken) LQGEEILSQASAAPE S1401
-
gap
0 1
FANCD2 (human) gap -
FANCD2 iso1 (human) gap -
FANCD2 iso3 (human) gap -
FANCD2 (mouse) EIISQDPsssEsNAE S1403-p
FANCD2 (rat) EIISQHPSSPENTSE S1405
FANCD2 (chicken) EILSQASAAPEEDSA A1405
S1404-p
EEIKsQNsQEstADE
Upstream
1 4
Treatment
  • ionizing_radiation
FANCD2 (human) EEIKsQNsQEstADE S1404-p
FANCD2 iso1 (human) EEIKSQNSQESTADE S1404
FANCD2 iso3 (human) gap -
FANCD2 (mouse) IISQDPsssEsNAED S1404-p
FANCD2 (rat) IISQHPSSPENTSED S1406
FANCD2 (chicken) ILSQASAAPEEDSAE A1406
Q1405
EIKsQNsQEstADEs
0 1
FANCD2 (human) EIKsQNsQEstADEs Q1405
FANCD2 iso1 (human) EIKSQNSQESTADES Q1405
FANCD2 iso3 (human) gap -
FANCD2 (mouse) ISQDPsssEsNAEDs S1405-p
FANCD2 (rat) ISQHPSSPENTSEDS P1407
FANCD2 (chicken) LSQASAAPEEDSAEG P1407
S1407-p
KsQNsQEstADEsED
0 3
FANCD2 (human) KsQNsQEstADEsED S1407-p
FANCD2 iso1 (human) KSQNSQESTADESED S1407
FANCD2 iso3 (human) gap -
FANCD2 (mouse) QDPsssEsNAEDsED S1407-p
FANCD2 (rat) QHPSSPENTSEDSED N1409
FANCD2 (chicken) gap -
T1408-p
sQNsQEstADEsEDD
0 1
FANCD2 (human) sQNsQEstADEsEDD T1408-p
FANCD2 iso1 (human) SQNSQESTADESEDD T1408
FANCD2 iso3 (human) gap -
FANCD2 (mouse) DPsssEsNAEDsEDG N1408
FANCD2 (rat) HPSSPENTSEDSEDG T1410
FANCD2 (chicken) gap -
S1412-p
QEstADEsEDDMSsQ
Upstream
0 24
Treatment
  • dasatinib
FANCD2 (human) QEstADEsEDDMSsQ S1412-p
FANCD2 iso1 (human) QESTADESEDDMSSQ S1412
FANCD2 iso3 (human) gap -
FANCD2 (mouse)