Other Species / Isoforms
  PRPS1 (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

  HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
K18-ub
SHQDLSQkIADRLGL
0 6
PRPS1 (human) SHQDLSQkIADRLGL K18-ub
PRPS1 (mouse) SHQDLSQkIADRLGL K18-ub
PRPS1 (rat) SHQDLSQKIADRLGL K18
K29-ub
RLGLELGkVVTKKFs
0 7
PRPS1 (human) RLGLELGkVVTKKFs K29-ub
PRPS1 (mouse) RLGLELGkVVTKKFS K29-ub
PRPS1 (rat) RLGLELGKVVTKKFs K29
S36-p
kVVTKKFsNQETCVE
0 2
PRPS1 (human) kVVTKKFsNQETCVE S36-p
PRPS1 (mouse) kVVTKKFSNQETCVE S36
PRPS1 (rat) KVVTKKFsNQETCVE S36-p
S47
TCVEIGESVRGEDVY
0 1
PRPS1 (human) TCVEIGESVRGEDVY S47
PRPS1 (mouse) TCVEIGESVRGEDVY S47
PRPS1 (rat) TCVEIGEsVRGEDVY S47-p
K99
FPYARQDKKDKsRAP
0 1
PRPS1 (human) FPYARQDKKDKsRAP K99
PRPS1 (mouse) FPYARQDkKDKSRAP K99-ac
PRPS1 (rat) FPYARQDKKDKSRAP K99
S103-p
RQDKKDKsRAPISAK
Upstream
Downstream
1 2
Effects on Modified Protein
  • enzymatic activity, induced
Effects on Biological Processes:
  • carcinogenesis, induced
  • cell cycle regulation
  • cell growth, induced
  • transcription, induced
Kinase, in vitro:
  • CDK1 (human)
Putative in vivo kinases:
  • CDK1 (human)
Treatment
  • AMG_900
  • Go_6983
  • H-89
  • Irinotecan
  • LY294002
  • MK-2206
  • PD98059
  • PHA793887
  • R547
  • SB216763
  • siRNA
  • SNS-032
  • U0126
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PRPS1 (human) RQDKKDKsRAPISAK S103-p
PRPS1 (mouse) RQDkKDKSRAPISAK S103
PRPS1 (rat) RQDKKDKSRAPISAK S103
Y146-p
DIPVDNLyAEPAVLK
0 9
PRPS1 (human) DIPVDNLyAEPAVLK Y146-p
PRPS1 (mouse) DIPVDNLYAEPAVLK Y146
PRPS1 (rat) DIPVDNLYAEPAVLK Y146
R156-m1
PAVLKWIrENISEWR
0 1
PRPS1 (human) PAVLKWIrENISEWR R156-m1
PRPS1 (mouse) PAVLKWIRENISEWR R156
PRPS1 (rat) PAVLKWIRENISEWR R156
K176-ac
SPDAGGAkRVTsIAD
0 6
PRPS1 (human) SPDAGGAkRVTsIAD K176-ac
PRPS1 (mouse) SPDAGGAkRVTSIAD K176-ac
PRPS1 (rat) SPDAGGAKRVTSIAD K176
K176-ub
SPDAGGAkRVTsIAD
0 5
PRPS1 (human) SPDAGGAkRVTsIAD K176-ub
PRPS1 (mouse) SPDAGGAkRVTSIAD K176-ub
PRPS1 (rat) SPDAGGAKRVTSIAD K176
S180-p
GGAkRVTsIADrLNV
Upstream
Downstream
1 5
Effects on Modified Protein
  • activity, inhibited
  • protein conformation
Effects on Biological Processes:
  • cell growth, inhibited
Kinase, in vitro:
  • AMPKA1 (human)
Putative in vivo kinases:
  • AMPKA1 (human)
Treatment
  • compound_C
  • hypoxia
PRPS1 (human) GGAkRVTsIADrLNV S180-p
PRPS1 (mouse) GGAkRVTSIADRLNV S180
PRPS1 (rat) GGAKRVTSIADRLNV S180
R184-m1
RVTsIADrLNVDFAL
0 1
PRPS1 (human) RVTsIADrLNVDFAL R184-m1
PRPS1 (mouse) RVTSIADRLNVDFAL R184
PRPS1 (rat) RVTSIADRLNVDFAL R184
K194-ac
VDFALIHkERKKANE
0 4
PRPS1 (human) VDFALIHkERKKANE K194-ac
PRPS1 (mouse) VDFALIHKERKKANE K194
PRPS1 (rat) VDFALIHkERKKANE K194-ac
K194-ub
VDFALIHkERKKANE
0 6
PRPS1 (human) VDFALIHkERKKANE K194-ub
PRPS1 (mouse) VDFALIHKERKKANE K194
PRPS1 (rat) VDFALIHKERKKANE K194
K212-ac
MVLVGDVkDRVAILV
0 1
PRPS1 (human) MVLVGDVkDRVAILV K212-ac
PRPS1 (mouse) MVLVGDVKDRVAILV K212
PRPS1 (rat) MVLVGDVKDRVAILV K212
K212-ub
MVLVGDVkDRVAILV
0 34
PRPS1 (human) MVLVGDVkDRVAILV K212-ub
PRPS1 (mouse) MVLVGDVkDRVAILV K212-ub
PRPS1 (rat) MVLVGDVKDRVAILV K212
T228-p
DMADTCGtICHAADk
Upstream
Downstream
1 2
Effects on Modified Protein
  • enzymatic activity, induced
  • molecular association, regulation
Effects on Biological Processes:
  • DNA repair, induced
  • cell growth, induced
Kinase, in vitro:
  • TBK1 (human)
Putative in vivo kinases:
  • TBK1 (human)
Regulatory protein:
  • cGAS (human)
  • ENPP1 (human)
  • IKKE (human)
  • Nik (human)
  • STING (human)
  • TREX1 (human)
view more >
Treatment
  • ADP
  • AMP
  • BX795
  • C-170
  • cGAMP
  • cGMP_analog
  • GMP
  • H-151
  • IMP
  • ionizing_radiation
  • MMS
  • siRNA
  • UVC
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PRPS1 (human) DMADTCGtICHAADk T228-p
PRPS1 (mouse) DMADTCGTICHAADK T228
PRPS1 (rat) DMADTCGTICHAADK T228
K235-ub
tICHAADkLLSAGAT
0 1
PRPS1 (human) tICHAADkLLSAGAT K235-ub
PRPS1 (mouse) TICHAADKLLSAGAT K235
PRPS1 (rat) TICHAADKLLSAGAT K235
Y245-p
SAGATRVyAILTHGI
0 20
PRPS1 (human) SAGATRVyAILTHGI Y245-p
PRPS1 (mouse) SAGATRVYAILTHGI Y245
PRPS1 (rat) SAGATRVYAILTHGI Y245
K280-ub
NTIPQEDkMKHCsKI
0 1
PRPS1 (human) NTIPQEDkMKHCsKI K280-ub
PRPS1 (mouse) NTIPQEDKMKHCSKI K280
PRPS1 (rat) NTIPQEDKMKHCSKI K280
S285-p
EDkMKHCsKIQVIDI
Upstream
Downstream
1 1
Effects on Modified Protein
  • molecular association, regulation
  • protein degradation
  • ubiquitination
Effects on Biological Processes:
  • carcinogenesis, inhibited
  • cell growth, inhibited
Kinase, in vitro:
  • LATS1 (human)
  • LATS2 (human)
Putative in vivo kinases:
  • LATS1 (human)
  • LATS2 (human)
Regulatory protein:
  • MST1 (human)
  • MST2 (human)
Treatment
  • (-)-Blebbistatin
  • stiff ECM substrate
  • U73122
  • Y27632
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PRPS1 (human) EDkMKHCsKIQVIDI S285-p
PRPS1 (mouse) EDKMKHCSKIQVIDI S285
PRPS1 (rat) EDKMKHCSKIQVIDI S285
S308-p
RRTHNGEsVSyLFSH
0 2
PRPS1 (human) RRTHNGEsVSyLFSH S308-p
PRPS1 (mouse) RRTHNGEsVSyLFSH S308-p
PRPS1 (rat) RRTHNGESVSYLFSH S308
Y311-p
HNGEsVSyLFSHVPL
0 13
PRPS1 (human) HNGEsVSyLFSHVPL Y311-p
PRPS1 (mouse) HNGEsVSyLFSHVPL Y311-p
PRPS1 (rat) HNGESVSYLFSHVPL Y311