Other Species / Isoforms
  Notch 1 (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

 HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
S900-p
CHCQAGYsGRNCETD
0 1
Notch 1 (human) CHCQAGYsGRNCETD S900-p
Notch 1 (mouse) CLCQAGYTGRNCESD T900
Notch 1 (rat) CLCQAGYTGRNCESD T900
K1317-ac
GCKGKPCkNGGTCAV
0 1
Notch 1 (human) GCKGKPCkNGGTCAV K1317-ac
Notch 1 (mouse) GCRGKPCKNGGVCAV K1317
Notch 1 (rat) GCRGKPCRNGGVCAV R1317
N1489
NFNDPWKNCTQSLQC
0 1
Notch 1 (human) NFNDPWKNCTQSLQC N1489
Notch 1 (mouse) NFNDPWKnCTQSLQC N1489-ng
Notch 1 (rat) NFNDPWKNCTQSLQC N1489
Y1677-p
DVRGSIVyLEIDNRQ
0 1
Notch 1 (human) DVRGSIVyLEIDNRQ Y1677-p
Notch 1 (mouse) DIRGSIVYLEIDNRQ Y1667
Notch 1 (rat) DIHGSIVYLEIDNRQ Y1667
K1774
LWFPEGFKVSEASKK
1 1
Notch 1 (human) LWFPEGFKVSEASKK K1774
Notch 1 (mouse) LWFPEGFkVSEASkk K1764-ac
Notch 1 (rat) LWFPEGFKVSEASKK K1764
K1780
FKVSEASKKKRREPL
1 1
Notch 1 (human) FKVSEASKKKRREPL K1780
Notch 1 (mouse) FkVSEASkkkRREPL K1770-ac
Notch 1 (rat) FKVSEASKKKRREPL K1770
K1781
KVSEASKKKRREPLG
1 1
Notch 1 (human) KVSEASKKKRREPLG K1781
Notch 1 (mouse) kVSEASkkkRREPLG K1771-ac
Notch 1 (rat) KVSEASKKKRREPLG K1771
K1782
VSEASKKKRREPLGE
1 1
Notch 1 (human) VSEASKKKRREPLGE K1782
Notch 1 (mouse) VSEASkkkRREPLGE K1772-ac
Notch 1 (rat) VSEASKKKRREPLGE K1772
S1791-p
REPLGEDsVGLkPLK
Upstream
Downstream
1 2
Effects on Modified Protein
  • protein degradation
Effects on Biological Processes:
  • cell cycle regulation
Kinase, in vitro:
  • PLK1 (human)
Putative in vivo kinases:
  • PLK1 (human)
Treatment
  • adriamycin
  • arsenite
  • BI2536
  • hydroxyurea
  • Ro3280
Notch 1 (human) REPLGEDsVGLkPLK S1791-p
Notch 1 (mouse) REPLGEDSVGLkPLK S1781
Notch 1 (rat) REPLGEDSVGLKPLK S1781
K1795
GEDsVGLKPLKNAsD
1 1
Notch 1 (human) GEDsVGLKPLKNAsD K1795
Notch 1 (mouse) GEDSVGLkPLKNAsD K1785-ac
Notch 1 (rat) GEDSVGLKPLKNASD K1785
K1795-ub
GEDsVGLkPLKNAsD
0 2
Notch 1 (human) GEDsVGLkPLKNAsD K1795-ub
Notch 1 (mouse) GEDSVGLkPLKNAsD K1785-ub
Notch 1 (rat) GEDSVGLKPLKNASD K1785
S1801-p
LkPLKNAsDGALMDD
1 1
Notch 1 (human) LkPLKNAsDGALMDD S1801-p
Notch 1 (mouse) LkPLKNAsDGALMDD S1791-p
Notch 1 (rat) LKPLKNASDGALMDD S1791
K1821-ub
GDEDLETkKFRFEEP
0 2
Notch 1 (human) GDEDLETkKFRFEEP K1821-ub
Notch 1 (mouse) GDEDLETKKFRFEEP K1811
Notch 1 (rat) GDEDLETKKFRFEEP K1811
T1861-p
RMSAMAPtPPQGEVD
0 2
Notch 1 (human) RMSAMAPtPPQGEVD T1861-p
Notch 1 (mouse) RMSAMAPtPPQGEVD T1851-p
Notch 1 (rat) RVSAMAPTPPQGEVD T1851
T1897-p
CSGGGLEtGNsEEEE
Upstream
Downstream
2 0
Effects on Modified Protein
  • activity, inhibited
  • molecular association, regulation
Effects on Biological Processes:
  • transcription, induced
  • transcription, inhibited
Regulatory protein:
  • CSL (mouse)
  • MAML1 (human)
Notch 1 (human) CSGGGLEtGNsEEEE T1897-p
Notch 1 (mouse) CSGGGLETGNSEEEE T1887
Notch 1 (rat) CSGGGLETGNSEEEE T1887
S1900-p
GGLEtGNsEEEEDAP
Upstream
Downstream
2 0
Effects on Modified Protein
  • activity, inhibited
  • molecular association, regulation
  • phosphorylation
Effects on Biological Processes:
  • transcription, induced
  • transcription, inhibited
Kinase, in vitro:
  • CK2A1 (human)
Putative in vivo kinases:
  • CK2A1 (human)
Treatment
  • TBCA
Notch 1 (human) GGLEtGNsEEEEDAP S1900-p
Notch 1 (mouse) GGLETGNSEEEEDAP S1890
Notch 1 (rat) GGLETGNSEEEEDAP S1890
T1927-p
LHNQTDRtGEtALHL
0 1
Notch 1 (human) LHNQTDRtGEtALHL T1927-p
Notch 1 (mouse) LHNQTDRTGETALHL T1917
Notch 1 (rat) LHNQTDRTGETALHL T1917
T1930-p
QTDRtGEtALHLAAR
0 1
Notch 1 (human) QTDRtGEtALHLAAR T1930-p
Notch 1 (mouse) QTDRTGETALHLAAR T1920
Notch 1 (rat) QTDRTGETALHLAAR T1920
S1941-p
LAARYSRsDAAKrLL
0 1
Notch 1 (human) LAARYSRsDAAKrLL S1941-p
Notch 1 (mouse) LAARYSRSDAAkRLL S1931
Notch 1 (rat) LAARYSRSDAAKRLL S1931
K1945
YSRsDAAKrLLEAsA
1 1
Notch 1 (human) YSRsDAAKrLLEAsA K1945
Notch 1 (mouse) YSRSDAAkRLLEASA K1935-ac
Notch 1 (rat) YSRSDAAKRLLEASA K1935
R1946-m1
SRsDAAKrLLEAsAD
0 1
Notch 1 (human) SRsDAAKrLLEAsAD R1946-m1
Notch 1 (mouse) SRSDAAkRLLEASAD R1936
Notch 1 (rat) SRSDAAKRLLEASAD R1936
S1951-p
AKrLLEAsADANIQD
0 2
Notch 1 (human) AKrLLEAsADANIQD S1951-p
Notch 1 (mouse) AkRLLEASADANIQD S1941
Notch 1 (rat) AKRLLEASADANIQD S1941
T1986-p
ILIRNRAtDLDARMH
0 1
Notch 1 (human) ILIRNRAtDLDARMH T1986-p
Notch 1 (mouse) ILLRNRATDLDARMH T1976
Notch 1 (rat) ILLRNRATDLDARMH T1976
T1996-p
DARMHDGttPLILAA
0 1
Notch 1 (human) DARMHDGttPLILAA T1996-p
Notch 1 (mouse) DARMHDGTTPLILAA T1986
Notch 1 (rat) DARMHDGTTPLILAA T1986
T1997-p
ARMHDGttPLILAAR
0 1
Notch 1 (human) ARMHDGttPLILAAR T1997-p
Notch 1 (mouse) ARMHDGTTPLILAAR T1987
Notch 1 (rat) ARMHDGTTPLILAAR T1987
R2060
NKDMQNNREETPLFL
1 1
Notch 1 (human) NKDMQNNREETPLFL R2060
Notch 1 (mouse) NKDMQNNkEETPLFL K2050-ac
Notch 1 (rat) NKDMQNNKEETPLFL K2050
Y2074-p
LAAREGSyETAKVLL
0 1
Notch 1 (human) LAAREGSyETAKVLL Y2074-p
Notch 1 (mouse) LAAREGSYETAkVLL Y2064
Notch 1 (rat) LAAREGSYETAKVLL Y2064
K2078
EGSyETAKVLLDHFA
1 1
Notch 1 (human) EGSyETAKVLLDHFA K2078
Notch 1 (mouse) EGSYETAkVLLDHFA K2068-ac
Notch 1 (rat) EGSYETAKVLLDHFA K2068
S2121-p
DEYNLVRsPQLHGAP
0 1
Notch 1 (human) DEYNLVRsPQLHGAP S2121-p
Notch 1 (mouse) DEYNLVRSPQLHGTA S2111
Notch 1 (rat) DEYNLVRSPQLHGTA S2111
T2132
HGAPLGGTPTLsPPL
1 0
Notch 1 (human) HGAPLGGTPTLsPPL T2132
Notch 1 (mouse) HGTALGGtPTLSPTL T2122-p
Notch 1 (rat) HGTALGGTPTLSPTL T2122
S2136-p
LGGTPTLsPPLCSPN
0 2
Notch 1 (human) LGGTPTLsPPLCSPN S2136-p
Notch 1 (mouse) LGGtPTLSPTLCSPN S2126
Notch 1 (rat) LGGTPTLSPTLCSPN S2126
Y2145-p
PLCSPNGyLGsLKPG
0 7
Notch 1 (human) PLCSPNGyLGsLKPG Y2145-p
Notch 1 (mouse) TLCSPNGYLGNLKSA Y2135
Notch 1 (rat) TLCSPNGYLGNLKSA Y2135
S2148-p
SPNGyLGsLKPGVQG
0 1
Notch 1 (human) SPNGyLGsLKPGVQG S2148-p
Notch 1 (mouse) SPNGYLGNLKSATQG N2138
Notch 1 (rat) SPNGYLGNLKSATQG N2138
K2156
LKPGVQGKkVRkPsS
1 1
Notch 1 (human) LKPGVQGKkVRkPsS K2156
Notch 1 (mouse) LKSATQGkkARkPsT K2146-ac
Notch 1 (rat) LKSATQGKKARKPST K2146
K2157-ac
KPGVQGKkVRkPsSk
Upstream
Downstream
2 1
Effects on Modified Protein
  • intracellular localization
Effects on Biological Processes:
  • apoptosis, inhibited
  • cell growth, induced
Treatment
  • siRNA
Notch 1 (human) KPGVQGKkVRkPsSk K2157-ac
Notch 1 (mouse) KSATQGkkARkPsTk K2147-ac
Notch 1 (rat) KSATQGKKARKPSTK K2147
K2160-ac
VQGKkVRkPsSkGLA
Upstream
Downstream
2 1
Effects on Modified Protein
  • intracellular localization
Effects on Biological Processes:
  • apoptosis, inhibited
  • cell growth, induced
Treatment
  • siRNA
Notch 1 (human) VQGKkVRkPsSkGLA K2160-ac
Notch 1 (mouse) TQGkkARkPsTkGLA K2150-ac
Notch 1 (rat) TQGKKARKPSTKGLA K2150
S2162-p
GKkVRkPsSkGLACG
1 5
Notch 1 (human) GKkVRkPsSkGLACG S2162-p
Notch 1 (mouse) GkkARkPsTkGLACG S2152-p
Notch 1 (rat) GKKARKPSTKGLACS S2152
K2164-ac
kVRkPsSkGLACGSk
Upstream
Downstream
2 1
Effects on Modified Protein
  • intracellular localization
Effects on Biological Processes:
  • apoptosis, inhibited
  • cell growth, induced
Treatment
  • siRNA
Notch 1 (human) kVRkPsSkGLACGSk K2164-ac
Notch 1 (mouse) kARkPsTkGLACGSk K2154-ac
Notch 1 (rat) KARKPSTKGLACSSK K2154
K2171-ac
kGLACGSkEAkDLKA
1 2
Notch 1 (human) kGLACGSkEAkDLKA K2171-ac
Notch 1 (mouse) kGLACGSkEAkDLKA K2161-ac
Notch 1 (rat) KGLACSSKEAKDLKA K2161
K2174-ac
ACGSkEAkDLKARRK
Upstream
Downstream
2 1
Effects on Modified Protein
  • intracellular localization
Effects on Biological Processes:
  • apoptosis, inhibited
  • cell growth, induced
Treatment
  • siRNA
Notch 1 (human) ACGSkEAkDLKARRK K2174-ac
Notch 1 (mouse) ACGSkEAkDLKARRK K2164-ac
Notch 1 (rat) ACSSKEAKDLKARRK K2164
R2263
AALGGGGRLAFETGP
1 1
Notch 1 (human) AALGGGGRLAFETGP R2263
Notch 1 (mouse) AALAGGSrLAFEPPP R2253-m2
Notch 1 (rat) AALAGGSRLAFEPPP R2253
R2272
AFETGPPRLSHLPVA
1 1
Notch 1 (human) AFETGPPRLSHLPVA R2272
Notch 1 (mouse) AFEPPPPrLSHLPVA R2262-m2
Notch 1 (rat) AFEPPPPRLSHLPVA R2262
S2289
TSTVLGSSSGGALNF
0 1
Notch 1 (human) TSTVLGSSSGGALNF S2289
Notch 1 (mouse) ASTVLSTnGTGAMnF N2279-ng
Notch 1 (rat) ASTVLSTNGTGAMNF N2279
N2295
SSSGGALNFTVGGST
0 1
Notch 1 (human) SSSGGALNFTVGGST N2295
Notch 1 (mouse) TnGTGAMnFTVGAPA N2285-ng
Notch 1 (rat) TNGTGAMNFTVGAPA N2285
N2305
VGGSTSLNGQCEWLS
0 1
Notch 1 (human) VGGSTSLNGQCEWLS N2305
Notch 1 (mouse) VGAPASLnGQCEWLP N2295-ng
Notch 1 (rat) VGAPASLNGQCEWLP N2295
R2313
GQCEWLSRLQSGMVP
1 1
Notch 1 (human) GQCEWLSRLQSGMVP R2313
Notch 1 (mouse) GQCEWLPrLQNGMVP R2303-m2
Notch 1 (rat) GQCEWLPRLQNGMVP R2303
Y2323-p
SGMVPNQyNPLRGSV
0 6
Notch 1 (human) SGMVPNQyNPLRGSV Y2323-p
Notch 1 (mouse) NGMVPSQYNPLrPGV Y2313
Notch 1 (rat) NGMVPSQYNPLRPGV Y2313
R2327
PNQyNPLRGSVAPGP
1 1
Notch 1 (human) PNQyNPLRGSVAPGP R2327
Notch 1 (mouse) PSQYNPLrPGVTPGT R2317-m2
Notch 1 (rat) PSQYNPLRPGVTPGT R2317
R2372
YQGLPSTRLATQPHL
1 1
Notch 1 (human) YQGLPSTRLATQPHL R2372
Notch 1 (mouse) YQGLPNTrLATQPHL R2361-m2
Notch 1 (rat) YQGLPNTRLATQPHL R2361
T2511-p
VPEHPFLtPsPEsPD
Upstream
Downstream
5 1
Effects on Modified Protein
  • activity, inhibited
  • molecular association, regulation
  • protein degradation
  • ubiquitination
Effects on Biological Processes:
  • carcinogenesis, altered
  • carcinogenesis, inhibited
  • cell growth, inhibited
  • cell motility, altered
  • cell motility, inhibited
  • signaling pathway regulation
  • transcription, inhibited
Kinase, in vitro:
  • CDK19 (human)
  • CDK3 (human)
  • CDK8 (human)
  • DYRK2 (human)
Putative in vivo kinases:
  • CDK19 (human)
  • CDK3 (human)
  • CDK8 (human)
  • DYRK2 (human)
  • HIPK2 (human)
  • MEKK1 (human)
Treatment
  • 1NM-PP1
  • adriamycin
  • CPT
  • curcumin
  • etoposide
  • harmine
  • siRNA
Notch 1 (human) VPEHPFLtPsPEsPD T2511-p
Notch 1 (mouse) VPEHPFLtPSPESPD T2487-p
Notch 1 (rat) VPEHPFLTPSPESPD T2487
S2513-p
EHPFLtPsPEsPDQW
Upstream
Downstream
1 1
Effects on Modified Protein
  • molecular association, regulation
  • protein degradation
  • ubiquitination
Effects on Biological Processes:
  • carcinogenesis, inhibited
Kinase, in vitro:
  • CDK19 (human)
  • CDK3 (human)
  • CDK8 (human)
Putative in vivo kinases:
  • CDK19 (human)
  • CDK3 (human)
  • CDK8 (human)
Notch 1 (human) EHPFLtPsPEsPDQW S2513-p
Notch 1 (mouse) EHPFLtPSPESPDQW S2489
Notch 1 (rat) EHPFLTPSPESPDQW S2489
S2516-p
FLtPsPEsPDQWsss
Upstream
Downstream
1 1
Effects on Modified Protein
  • molecular association, regulation
  • protein degradation
  • ubiquitination
Effects on Biological Processes:
  • carcinogenesis, inhibited
Putative in vivo kinases:
  • CDK19 (human)
  • CDK3 (human)
  • CDK8 (human)
Notch 1 (human) FLtPsPEsPDQWsss S2516-p
Notch 1 (mouse) FLtPSPESPDQWSSS S2492
Notch 1 (rat) FLTPSPESPDQWSSS S2492
S2521-p
PEsPDQWssssPHSN
Downstream
1 0
Effects on Modified Protein
  • protein degradation
  • receptor inactivation, altered
Notch 1 (human) PEsPDQWssssPHSN S2521-p
Notch 1 (mouse) PESPDQWSSSSPHSN S2497
Notch 1 (rat) PESPDQWSSSSPHSN S2497
S2522-p
EsPDQWssssPHSNV
Downstream
1 0
Effects on Modified Protein
  • protein degradation
  • receptor inactivation, altered
Notch 1 (human) EsPDQWssssPHSNV S2522-p
Notch 1 (mouse) ESPDQWSSSSPHSNI S2498
Notch 1 (rat) ESPDQWSSSSPHSNI S2498
S2523-p
sPDQWssssPHSNVS
Downstream
1 0
Effects on Modified Protein
  • protein degradation
  • receptor inactivation, altered
Notch 1 (human) sPDQWssssPHSNVS S2523-p
Notch 1 (mouse) SPDQWSSSSPHSNIS S2499
Notch 1 (rat) SPDQWSSSSPHSNIS S2499
S2524-p
PDQWssssPHSNVSD
Downstream
1 0
Effects on Modified Protein
  • protein degradation
  • receptor inactivation, altered
Notch 1 (human) PDQWssssPHSNVSD S2524-p
Notch 1 (mouse) PDQWSSSSPHSNISD S2500
Notch 1 (rat) PDQWSSSSPHSNISD S2500