Other Species / Isoforms
  MEKK3 (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

 HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
-
gap
0 2
MEKK3 (human) gap -
MEKK3 iso2 (human) SSSALLNsPtVTTSS S55
MEKK3 (mouse) gap -
MEKK3 (rat) gap -
-
gap
0 1
MEKK3 (human) gap -
MEKK3 iso2 (human) SALLNsPtVTTSSCA T57
MEKK3 (mouse) gap -
MEKK3 (rat) gap -
S130
QDRNHNSssPHSGVS
0 1
MEKK3 (human) QDRNHNSssPHSGVS S130
MEKK3 iso2 (human) QDRNHNSSSPHSGVS S161
MEKK3 (mouse) QDRNHTSSsPHSGVS S130
MEKK3 (rat) QDRNHTSSSPHSGVS S130
S131
DRNHNSssPHSGVSR
0 4
MEKK3 (human) DRNHNSssPHSGVSR S131
MEKK3 iso2 (human) DRNHNSSSPHSGVSR S162
MEKK3 (mouse) DRNHTSSsPHSGVSR S131
MEKK3 (rat) DRNHTSSSPHSGVSR S131
S145
RQVRIKAsQsAGDIN
0 3
MEKK3 (human) RQVRIKAsQsAGDIN S145
MEKK3 iso2 (human) RQVRIKASQSAGDIN S176
MEKK3 (mouse) RQVRIKPsQsAGDIN S145
MEKK3 (rat) RQVRVKPSQSAGDIN S145
S147
VRIKAsQsAGDINTI
0 25
MEKK3 (human) VRIKAsQsAGDINTI S147
MEKK3 iso2 (human) VRIKASQSAGDINTI S178
MEKK3 (mouse) VRIKPsQsAGDINtI S147
MEKK3 (rat) VRVKPSQSAGDINTI S147
T153
QsAGDINTIyQPPEP
0 1
MEKK3 (human) QsAGDINTIyQPPEP T153
MEKK3 iso2 (human) QSAGDINTIYQPPEP T184
MEKK3 (mouse) QsAGDINtIyQAPEP T153
MEKK3 (rat) QSAGDINTIYQAPEP T153
Y155
AGDINTIyQPPEPRs
0 61
MEKK3 (human) AGDINTIyQPPEPRs Y155
MEKK3 iso2 (human) AGDINTIYQPPEPRS Y186
MEKK3 (mouse) AGDINtIyQAPEPRS Y155
MEKK3 (rat) AGDINTIYQAPEPRS Y155
S162
yQPPEPRsRHLsVss
0 1
MEKK3 (human) yQPPEPRsRHLsVss S162
MEKK3 iso2 (human) YQPPEPRSRHLSVSS S193
MEKK3 (mouse) yQAPEPRSRHLsVsS S162
MEKK3 (rat) YQAPEPRSRHLSVSS S162
S166
EPRsRHLsVssQNPG
Upstream
2 71
Treatment
  • angiotensin_2
  • SII_angiotensin_2
MEKK3 (human) EPRsRHLsVssQNPG S166
MEKK3 iso2 (human) EPRSRHLSVSSQNPG S197
MEKK3 (mouse) EPRSRHLsVsSQNPG S166
MEKK3 (rat) EPRSRHLSVSSQNPG S166
S168
RsRHLsVssQNPGRs
0 3
MEKK3 (human) RsRHLsVssQNPGRs S168
MEKK3 iso2 (human) RSRHLSVSSQNPGRS S199
MEKK3 (mouse) RSRHLsVsSQNPGRs S168
MEKK3 (rat) RSRHLSVSSQNPGRS S168
S169
sRHLsVssQNPGRss
0 8
MEKK3 (human) sRHLsVssQNPGRss S169
MEKK3 iso2 (human) SRHLSVSSQNPGRSS S200
MEKK3 (mouse) SRHLsVsSQNPGRss S169
MEKK3 (rat) SRHLSVSSQNPGRSS S169
S175
ssQNPGRssPPPGYV
0 4
MEKK3 (human) ssQNPGRssPPPGYV S175
MEKK3 iso2 (human) SSQNPGRSSPPPGYV S206
MEKK3 (mouse) sSQNPGRssPPPGYV S175
MEKK3 (rat) SSQNPGRSSPPPGYV S175
S176
sQNPGRssPPPGYVP
Upstream
0 19
Treatment
  • ischemia
MEKK3 (human) sQNPGRssPPPGYVP S176
MEKK3 iso2 (human) SQNPGRSSPPPGYVP S207
MEKK3 (mouse) SQNPGRssPPPGYVP S176
MEKK3 (rat) SQNPGRSSPPPGYVP S176
S194
QHIARQGsYTSINSE
0 1
MEKK3 (human) QHIARQGsYTSINSE S194
MEKK3 iso2 (human) QHIARQGSYTSINSE S225
MEKK3 (mouse) QHIARQGSYTSINSE S194
MEKK3 (rat) QHIARQGSYTSINSE S194
S234
SCQSLDRsADsPSFR
0 2
MEKK3 (human) SCQSLDRsADsPSFR S234
MEKK3 iso2 (human) SCQSLDRSADSPSFR S265
MEKK3 (mouse) SCQSLDRSADsPSFR S234
MEKK3 (rat) SCQSLDRSADSPSFR S234
S237
SLDRsADsPSFRKSR
0 11
MEKK3 (human) SLDRsADsPSFRKSR S237
MEKK3 iso2 (human) SLDRSADSPSFRKSR S268
MEKK3 (mouse) SLDRSADsPSFRKSQ S237
MEKK3 (rat) SLDRSADSPSFRKSQ S237
S250
SRMSRAQsFPDNRQE
0 51
MEKK3 (human) SRMSRAQsFPDNRQE S250
MEKK3 iso2 (human) SRMSRAQSFPDNRQE S281
MEKK3 (mouse) SQMSRARsFPDNRKE S250
MEKK3 (rat) SQMSRARSFPDNRKE S250
T263
QEYSDREtQLyDKGV
0 1
MEKK3 (human) QEYSDREtQLyDKGV T263
MEKK3 iso2 (human) QEYSDRETQLYDKGV T294
MEKK3 (mouse) KECSDRETQLYDKGV T263
MEKK3 (rat) KECSDRETQLYDKGV T263
Y266
SDREtQLyDKGVKGG
0 1
MEKK3 (human) SDREtQLyDKGVKGG Y266
MEKK3 iso2 (human) SDRETQLYDKGVKGG Y297
MEKK3 (mouse) SDRETQLYDKGVKGG Y266
MEKK3 (rat) SDRETQLYDKGVKGG Y266
T274
DKGVKGGtyPRRYHV
0 4
MEKK3 (human) DKGVKGGtyPRRYHV T274
MEKK3 iso2 (human) DKGVKGGTYPRRYHV T305
MEKK3 (mouse) DKGVKGGtYPRRYHV T274
MEKK3 (rat) DKGVKGGTYPRRYHV T274
Y275
KGVKGGtyPRRYHVS
0 3
MEKK3 (human) KGVKGGtyPRRYHVS Y275
MEKK3 iso2 (human) KGVKGGTYPRRYHVS Y306
MEKK3 (mouse) KGVKGGtYPRRYHVS Y275
MEKK3 (rat) KGVKGGTYPRRYHVS Y275
Y288
VSVHHKDysDGRRtF
0 1
MEKK3 (human) VSVHHKDysDGRRtF Y288
MEKK3 iso2 (human) VSVHHKDYSDGRRTF Y319
MEKK3 (mouse) VSVHHKDYNDGRRtF Y288
MEKK3 (rat) VSVHHKDYNDGRRTF Y288
S289
SVHHKDysDGRRtFP
0 1
MEKK3 (human) SVHHKDysDGRRtFP S289
MEKK3 iso2 (human) SVHHKDYSDGRRTFP S320
MEKK3 (mouse) SVHHKDYNDGRRtFP N289
MEKK3 (rat) SVHHKDYNDGRRTFP N289
T294
DysDGRRtFPRIRRH
Upstream
Downstream
1 5
Effects on Modified Protein
  • molecular association, regulation
Treatment
  • LPS
  • TNF
MEKK3 (human) DysDGRRtFPRIRRH T294
MEKK3 iso2 (human) DYSDGRRTFPRIRRH T325
MEKK3 (mouse) DYNDGRRtFPRIRRH T294
MEKK3 (rat) DYNDGRRTFPRIRRH T294
S312
LFTLVPSsRsLstNG
0 2
MEKK3 (human) LFTLVPSsRsLstNG S312
MEKK3 iso2 (human) LFTLVPSSRSLSTNG S343
MEKK3 (mouse) LFTLVPSsRSLStNG S312
MEKK3 (rat) LFTLVPSSRSLSTNG S312
S314
TLVPSsRsLstNGEN
0 1
MEKK3 (human) TLVPSsRsLstNGEN S314
MEKK3 iso2 (human) TLVPSSRSLSTNGEN S345
MEKK3 (mouse) TLVPSsRSLStNGEN S314
MEKK3 (rat) TLVPSSRSLSTNGEN S314
S316
VPSsRsLstNGENMG
0 5
MEKK3 (human) VPSsRsLstNGENMG S316
MEKK3 iso2 (human) VPSSRSLSTNGENMG S347
MEKK3 (mouse) VPSsRSLStNGENMG S316
MEKK3 (rat) VPSSRSLSTNGENMG S316
T317
PSsRsLstNGENMGL
0 5
MEKK3 (human) PSsRsLstNGENMGL T317
MEKK3 iso2 (human) PSSRSLSTNGENMGL T348
MEKK3 (mouse) PSsRSLStNGENMGV T317
MEKK3 (rat) PSSRSLSTNGENMGA T317
S337
DPRGRLRsADsENAL
Upstream
2 78
Treatment
  • angiotensin_2
  • MG132_withdrawal
  • selumetinib
  • SII_angiotensin_2
  • vemurafenib
MEKK3 (human) DPRGRLRsADsENAL S337
MEKK3 iso2 (human) DPRGRLRSADSENAL S368
MEKK3 (mouse) DPRGRLRsADsENAL S337
MEKK3 (rat) DPRGRLRsADsENAL S337
S340
GRLRsADsENALsVQ
Upstream
0 78
Treatment
  • angiotensin_2
  • BI2536
  • LPA
  • selumetinib
  • SII_angiotensin_2
  • vemurafenib
MEKK3 (human) GRLRsADsENALsVQ S340
MEKK3 iso2 (human) GRLRSADSENALSVQ S371
MEKK3 (mouse) GRLRsADsENALTVQ S340
MEKK3 (rat) GRLRsADsENALTVQ S340
S345
ADsENALsVQERNVP
Upstream
0 1
Treatment
  • BI2536
MEKK3 (human) ADsENALsVQERNVP S345
MEKK3 iso2 (human) ADSENALSVQERNVP S376
MEKK3 (mouse) ADsENALTVQERNVP T345
MEKK3 (rat) ADsENALTVQERSVP T345
S355
ERNVPTKsPsAPINW
0 14
MEKK3 (human) ERNVPTKsPsAPINW S355
MEKK3 iso2 (human) ERNVPTKSPSAPINW S386
MEKK3 (mouse) ERNVPTKsPsAPINW S355
MEKK3 (rat) ERSVPTKSPSAPINW S355
S357
NVPTKsPsAPINWRR
0 3
MEKK3 (human) NVPTKsPsAPINWRR S357
MEKK3 iso2 (human) NVPTKSPSAPINWRR S388
MEKK3 (mouse) NVPTKsPsAPINWRR S357
MEKK3 (rat) SVPTKSPSAPINWRR S357
S464
AYGALTEsVTRKYTR
0 1
MEKK3 (human) AYGALTEsVTRKYTR S464
MEKK3 iso2 (human) AYGALTESVTRKYTR S495
MEKK3 (mouse) AYGALTESVTRKYTR S464
MEKK3 (rat) AYGALTESVTRKYTR S464
T516
GASKRLQtICMsGTG
Upstream
Downstream
2 0
Effects on Modified Protein
  • enzymatic activity, induced
Phosphatases, in vitro:
  • PPP2CA (human)
Putative upstream phosphatases:
  • PPP2CA (human)
Regulatory protein:
  • PPM1B (human)
  • PPM1J (human)
  • PPM1K (human)
  • PPM1M (human)
  • PPP2CA (human)
  • PPP3CB (human)
  • PPP5C (human)
  • PPP6C (human)
  • PPPM1A (human)
  • PPTC7 (human)
Treatment
  • ionomycin
  • LPA
  • phorbol_ester
MEKK3 (human) GASKRLQtICMsGTG T516
MEKK3 iso2 (human) GASKRLQTICMSGTG T547
MEKK3 (mouse) GASKRLQTICMSGTG T516
MEKK3 (rat) GASKRLQTICMSGTG T516
S520
RLQtICMsGTGMRsV
Upstream
Downstream
2 1
Effects on Modified Protein
  • enzymatic activity, induced
Phosphatases, in vitro:
  • PPP2CA (human)
Putative upstream phosphatases:
  • PPP2CA (human)
Regulatory protein:
  • PPM1B (human)
  • PPM1J (human)
  • PPM1K (human)
  • PPM1M (human)
  • PPP2CA (human)
  • PPP3CB (human)
  • PPP5C (human)
  • PPP6C (human)
  • PPPM1A (human)
  • PPTC7 (human)
Treatment
  • ionomycin
  • LPA
  • phorbol_ester
MEKK3 (human) RLQtICMsGTGMRsV S520
MEKK3 iso2 (human) RLQTICMSGTGMRSV S551
MEKK3 (mouse) RLQTICMSGTGIRsV S520
MEKK3 (rat) RLQTICMSGTGMRSV S520
S526
MsGTGMRsVtGtPYW
Upstream
Downstream
4 2
Effects on Modified Protein
  • enzymatic activity, induced
Effects on Biological Processes:
  • transcription, altered
Treatment
  • LPS
  • okadaic_acid
MEKK3 (human) MsGTGMRsVtGtPYW S526
MEKK3 iso2 (human) MSGTGMRSVTGTPYW S557
MEKK3 (mouse) MSGTGIRsVTGTPYW S526
MEKK3 (rat) MSGTGMRSVTGTPYW S526
T528
GTGMRsVtGtPYWMS
1 0
MEKK3 (human) GTGMRsVtGtPYWMS T528
MEKK3 iso2 (human) GTGMRSVTGTPYWMS T559
MEKK3 (mouse) GTGIRsVTGTPYWMS T528
MEKK3 (rat) GTGMRSVTGTPYWMS T528
T530
GMRsVtGtPYWMSPE
1 0
MEKK3 (human) GMRsVtGtPYWMSPE T530
MEKK3 iso2 (human) GMRSVTGTPYWMSPE T561
MEKK3 (mouse) GIRsVTGTPYWMSPE T530
MEKK3 (rat) GMRSVTGTPYWMSPE T530