Other Species / Isoforms
  DOK1 (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

 HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
Y30-p
RKTWAVLyPAsPHGV
0 1
DOK1 (human) RKTWAVLyPAsPHGV Y30-p
DOK1 iso3 (human) gap -
DOK1 (mouse) RKTWAVLYPASPHGV Y30
DOK1 (rat) KKTWAVLYPASPHGV Y30
S33-p
WAVLyPAsPHGVArL
0 14
DOK1 (human) WAVLyPAsPHGVArL S33-p
DOK1 iso3 (human) gap -
DOK1 (mouse) WAVLYPASPHGVARL S33
DOK1 (rat) WAVLYPASPHGVARL S33
R39-m1
AsPHGVArLEFFDHk
0 1
DOK1 (human) AsPHGVArLEFFDHk R39-m1
DOK1 iso3 (human) gap -
DOK1 (mouse) ASPHGVARLEFFDHK R39
DOK1 (rat) ASPHGVARLEFFDHK R39
K46-ub
rLEFFDHkGsSSGGG
0 1
DOK1 (human) rLEFFDHkGsSSGGG K46-ub
DOK1 iso3 (human) under review -
DOK1 (mouse) RLEFFDHKGsSSRGG K46
DOK1 (rat) RLEFFDHKGSSSGGG K46
S48-p
EFFDHkGsSSGGGrG
0 4
DOK1 (human) EFFDHkGsSSGGGrG S48-p
DOK1 iso3 (human) gap -
DOK1 (mouse) EFFDHKGsSSRGGRG S48-p
DOK1 (rat) EFFDHKGSSSGGGRG S48
R54-m1
GsSSGGGrGSSRRLD
0 1
DOK1 (human) GsSSGGGrGSSRRLD R54-m1
DOK1 iso3 (human) gap -
DOK1 (mouse) GsSSRGGRGGSRRLD R54
DOK1 (rat) GSSSGGGRGGSRRLD R54
K63
SSRRLDCKVIRLAEC
0 1
DOK1 (human) SSRRLDCKVIRLAEC K63
DOK1 iso3 (human) gap -
DOK1 (mouse) GSRRLDCkMIRLAEC K63-ac
DOK1 (rat) GSRRLDCKMIRLAEC K63
T93-p
ATAFRLDtAQRSHLL
0 1
DOK1 (human) ATAFRLDtAQRSHLL T93-p
DOK1 iso3 (human) gap -
DOK1 (mouse) AVAFRLDTAQRSHLL T93
DOK1 (rat) ASAFRLDTAQRSHLL T93
K121-ub
LCRNAFPkGsWtLAP
0 1
DOK1 (human) LCRNAFPkGsWtLAP K121-ub
DOK1 iso3 (human) under review -
DOK1 (mouse) LCRTAFPKGGWALAQ K121
DOK1 (rat) LCRTAFPKGGWALAQ K121
S123-p
RNAFPkGsWtLAPTD
0 1
DOK1 (human) RNAFPkGsWtLAPTD S123-p
DOK1 iso3 (human) gap -
DOK1 (mouse) RTAFPKGGWALAQTE G123
DOK1 (rat) RTAFPKGGWALAQTE G123
T125-p
AFPkGsWtLAPTDNP
0 1
DOK1 (human) AFPkGsWtLAPTDNP T125-p
DOK1 iso3 (human) gap -
DOK1 (mouse) AFPKGGWALAQTENQ A125
DOK1 (rat) AFPKGGWALAQTENP A125
S136
TDNPPKLSALEMLEN
0 1
DOK1 (human) TDNPPKLSALEMLEN S136
DOK1 iso3 (human) gap -
DOK1 (mouse) TENQPKFsALEMLEN S136-p
DOK1 (rat) TENPPKFSALEMLEN S136
Y146-p
EMLENSLySPTWEGS
Upstream
Downstream
2 3
Effects on Modified Protein
  • molecular association, regulation
Regulatory protein:
  • CD2 (human)
DOK1 (human) EMLENSLySPTWEGS Y146-p
DOK1 iso3 (human) _MLENSLYSPTWEGS Y7
DOK1 (mouse) EMLENSLySPTWEGS Y146-p
DOK1 (rat) EMLENSLYSPTWEGS Y146
S217-p
GRDKVMFsFEAGRRC
0 1
DOK1 (human) GRDKVMFsFEAGRRC S217-p
DOK1 iso3 (human) GRDKVMFSFEAGRRC S78
DOK1 (mouse) GRDKVMFSFEAGRRC S217
DOK1 (rat) GRDKVMFSFEAGRRC S217
K257-ub
HRQKAQGkAGQGHDV
0 1
DOK1 (human) HRQKAQGkAGQGHDV K257-ub
DOK1 iso3 (human) HRQKAQGKAGQGHDV K118
DOK1 (mouse) QQQKAQGKVGQAQDI K257
DOK1 (rat) QQQKAQGKVGQGQDI K257
A267
QGHDVLRADsHEGEV
0 1
DOK1 (human) QGHDVLRADsHEGEV A267
DOK1 iso3 (human) QGHDVLRADSHEGEV A128
DOK1 (mouse) QAQDILRtDsHDGEt T267-p
DOK1 (rat) QGQDITRTDSHDGET T267
S269-p
HDVLRADsHEGEVAE
Upstream
0 37
Treatment
  • anti-CD3
  • dasatinib
  • EGF
  • U0126
DOK1 (human) HDVLRADsHEGEVAE S269-p
DOK1 iso3 (human) HDVLRADSHEGEVAE S130
DOK1 (mouse) QDILRtDsHDGEtEG S269-p
DOK1 (rat) QDITRTDSHDGETEG S269
A275
DsHEGEVAEGKLPsP
0 2
DOK1 (human) DsHEGEVAEGKLPsP A275
DOK1 iso3 (human) DSHEGEVAEGKLPSP A136
DOK1 (mouse) tDsHDGEtEGKTVPP T274-p
DOK1 (rat) TDSHDGETEGKMAPT T274
S281-p
VAEGKLPsPPGPQEL
0 6
DOK1 (human) VAEGKLPsPPGPQEL S281-p
DOK1 iso3 (human) VAEGKLPSPPGPQEL S142
DOK1 (mouse) EtEGKTVPPPVPQDP P280
DOK1 (rat) ETEGKMAPTPVPQEP P280
S291-p
GPQELLDsPPALyAE
1 9
DOK1 (human) GPQELLDsPPALyAE S291-p
DOK1 iso3 (human) GPQELLDSPPALYAE S152
DOK1 (mouse) VPQDPLGsPPALyAE S290-p
DOK1 (rat) VPQEPLGsPPALYAE S290-p
Y296-p
LDsPPALyAEPLDSL
Upstream
Downstream
4 178
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
Treatment
  • anti-CD28
  • anti-CD3
DOK1 (human) LDsPPALyAEPLDSL Y296-p
DOK1 iso3 (human) LDSPPALYAEPLDSL Y157
DOK1 (mouse) LGsPPALyAEPLDSL Y295-p
DOK1 (rat) LGsPPALYAEPLDSL Y295
S310-p
LRIAPCPsQDsLysD
0 9
DOK1 (human) LRIAPCPsQDsLysD S310-p
DOK1 iso3 (human) LRIAPCPSQDSLYSD S171
DOK1 (mouse) LRIPPGPSQDSVysD S309
DOK1 (rat) LRIPPGPSQDSLYSD S309
S313-p
APCPsQDsLysDPLD
0 10
DOK1 (human) APCPsQDsLysDPLD S313-p
DOK1 iso3 (human) APCPSQDSLYSDPLD S174
DOK1 (mouse) PPGPSQDSVysDPLG S312
DOK1 (rat) PPGPSQDSLYSDPLG S312
Y315-p
CPsQDsLysDPLDST
Upstream
Downstream
1 356
Effects on Modified Protein
  • molecular association, regulation
Regulatory protein:
  • FGFR1 (human)
Treatment
  • anti-CD28
  • anti-CD3
  • ephrin_B1
  • Su11274
DOK1 (human) CPsQDsLysDPLDST Y315-p
DOK1 iso3 (human) CPSQDSLYSDPLDST Y176
DOK1 (mouse) GPSQDSVysDPLGST Y314-p
DOK1 (rat) GPSQDSLYSDPLGST Y314
S316-p
PsQDsLysDPLDSTS
0 3
DOK1 (human) PsQDsLysDPLDSTS S316-p
DOK1 iso3 (human) PSQDSLYSDPLDSTS S177
DOK1 (mouse) PSQDSVysDPLGSTP S315-p
DOK1 (rat) PSQDSLYSDPLGSTP S315
Y337-p
VQRKKPLyWDLyEHA
1 353
DOK1 (human) VQRKKPLyWDLyEHA Y337-p
DOK1 iso3 (human) VQRKKPLYWDLYEHA Y198
DOK1 (mouse) VHSKKPLyWDLyGHV Y336-p
DOK1 (rat) VQRKKPLYWDLYGHV Y336
Y341-p
KPLyWDLyEHAQQQL
0 324
DOK1 (human) KPLyWDLyEHAQQQL Y341-p
DOK1 iso3 (human) KPLYWDLYEHAQQQL Y202
DOK1 (mouse) KPLyWDLyGHVQQQL Y340-p
DOK1 (rat) KPLYWDLYGHVQQQL Y340
T354-p
QLLKAKLtDPKEDPI
0 20
DOK1 (human) QLLKAKLtDPKEDPI T354-p
DOK1 iso3 (human) QLLKAKLTDPKEDPI T215
DOK1 (mouse) QLLKTKLtDsKEDPI T353-p
DOK1 (rat) QLLKTKLIDSKEDPI I353
P356
LKAKLtDPKEDPIyD
0 2
DOK1 (human) LKAKLtDPKEDPIyD P356
DOK1 iso3 (human) LKAKLTDPKEDPIYD P217
DOK1 (mouse) LKTKLtDsKEDPIyD S355-p
DOK1 (rat) LKTKLIDSKEDPIyD S355
Y362-p
DPKEDPIyDEPEGLA
Upstream
Downstream
8 519
Effects on Modified Protein
  • molecular association, regulation
  • phosphorylation
Kinase, in vitro:
  • INSR (human)
Putative in vivo kinases:
  • Src (human)
Regulatory protein:
  • EGFR (human)
Treatment
  • anti-CD28
  • anti-CD3
  • ephrin_B1
DOK1 (human) DPKEDPIyDEPEGLA Y362-p
DOK1 iso3 (human) DPKEDPIYDEPEGLA Y223
DOK1 (mouse) DsKEDPIyDEPEGLA Y361-p
DOK1 (rat) DSKEDPIyDEPEGLA Y361-p
Y377-p
PVPPQGLyDLPREPK
2 364
DOK1 (human) PVPPQGLyDLPREPK Y377-p
DOK1 iso3 (human) PVPPQGLYDLPREPK Y238
DOK1 (mouse) PAPPRGLyDLPQEPR Y376-p
DOK1 (rat) PAPLRGLYDLPQEPK Y376
K394-ub
WWCQARVkEEGyELP
0 1
DOK1 (human) WWCQARVkEEGyELP K394-ub
DOK1 iso3 (human) WWCQARVKEEGYELP K255
DOK1 (mouse) WWCQARLKEEGyELP K393
DOK1 (rat) WWCQARLKEEGYELP K393
Y398-p
ARVkEEGyELPyNPA
Upstream
Downstream
4 551
Effects on Modified Protein
  • molecular association, regulation
  • phosphorylation
Kinase, in vitro:
  • INSR (human)
  • Ret (human)
Regulatory protein:
  • GRB10 (human)
Treatment
  • insulin
DOK1 (human) ARVkEEGyELPyNPA Y398-p
DOK1 iso3 (human) ARVKEEGYELPYNPA Y259
DOK1 (mouse) ARLKEEGyELPyNPA Y397-p
DOK1 (rat) ARLKEEGYELPYNPA Y397
Y402-p
EEGyELPyNPAtDDy
0 157
DOK1 (human) EEGyELPyNPAtDDy Y402-p
DOK1 iso3 (human) EEGYELPYNPATDDY Y263
DOK1 (mouse) EEGyELPyNPAtDDy Y401-p
DOK1 (rat) EEGYELPYNPATDDY Y401
T406-p
ELPyNPAtDDyAVPP
0 55
DOK1 (human) ELPyNPAtDDyAVPP T406-p
DOK1 iso3 (human) ELPYNPATDDYAVPP T267
DOK1 (mouse) ELPyNPAtDDyAVPP T405-p
DOK1 (rat) ELPYNPATDDYAVPP T405
Y409-p
yNPAtDDyAVPPPRS
Upstream
2 780
Regulatory protein:
  • ZAP70 (human)
Treatment
  • anti-CD28
  • anti-CD3
  • ephrin_B1
DOK1 (human) yNPAtDDyAVPPPRS Y409-p
DOK1 iso3 (human) YNPATDDYAVPPPRS Y270
DOK1 (mouse) yNPAtDDyAVPPPRs Y408-p
DOK1 (rat) YNPATDDYAVPPPRS Y408
S416
yAVPPPRSTKPLLAP
0 14
DOK1 (human) yAVPPPRSTKPLLAP S416
DOK1 iso3 (human) YAVPPPRSTKPLLAP S277
DOK1 (mouse) yAVPPPRsPKPAPAP S415-p
DOK1 (rat) YAVPPPRSSKPTPAP S415
P433
QGPAFPEPGtATGsG
0 1
DOK1 (human) QGPAFPEPGtATGsG P433
DOK1 iso3 (human) QGPAFPEPGTATGSG P294
DOK1 (mouse) QGLILPEsGttRGsG S432-p
DOK1 (rat) QGLILPESGTTAGSG S432
T435-p
PAFPEPGtATGsGIK
0 2
DOK1 (human) PAFPEPGtATGsGIK T435-p
DOK1 iso3 (human) PAFPEPGTATGSGIK T296
DOK1 (mouse) LILPEsGttRGsGSK T434-p
DOK1 (rat) LILPESGTTAGSGSK T434
A436
AFPEPGtATGsGIKs
0 1
DOK1 (human) AFPEPGtATGsGIKs A436
DOK1 iso3 (human) AFPEPGTATGSGIKS A297
DOK1 (mouse) ILPEsGttRGsGSKG T435-p
DOK1 (rat) ILPESGTTAGSGSKG T435
S439-p
EPGtATGsGIKsHNs
Upstream
Downstream
1 1
Effects on Biological Processes:
  • cell growth, inhibited
  • cell motility, induced
Putative in vivo kinases:
  • IKKB (human)
DOK1 (human) EPGtATGsGIKsHNs S439-p
DOK1 iso3 (human) EPGTATGSGIKSHNS S300
DOK1 (mouse) EsGttRGsGSKGFSS S438-p
DOK1 (rat) ESGTTAGSGSKGSDT S438
S443-p
ATGsGIKsHNsALys
Upstream
Downstream
1 0
Effects on Biological Processes:
  • cell growth, inhibited
  • cell motility, induced
Putative in vivo kinases:
  • IKKB (human)
Treatment
  • IL-1a
  • TNF
DOK1 (human) ATGsGIKsHNsALys S443-p
DOK1 iso3 (human) ATGSGIKSHNSALYS S304
DOK1 (mouse) GsGSKGFSSDTALyS S444
DOK1 (rat) gap -
S446-p
sGIKsHNsALysQVQ
Upstream
Downstream
1 25
Effects on Biological Processes:
  • cell growth, inhibited
  • cell motility, induced
Putative in vivo kinases:
  • IKKB (human)
DOK1 (human) sGIKsHNsALysQVQ S446-p
DOK1 iso3 (human) SGIKSHNSALYSQVQ S307
DOK1 (mouse) SKGFSSDTALySQVQ T447
DOK1 (rat) SGSKGSDTALYSQVQ T445
Y449-p
KsHNsALysQVQKSG
Upstream
Downstream
3 1053
Effects on Modified Protein
  • molecular association, regulation
Regulatory protein:
  • FGFR1 (human)
Treatment
  • anti-CD3
  • ephrin_B1
  • ephrin_B2
  • gefitinib
  • Su11274
  • U0126
DOK1 (human) KsHNsALysQVQKSG Y449-p
DOK1 iso3 (human) KSHNSALYSQVQKSG Y310
DOK1 (mouse) FSSDTALySQVQKSG Y450-p
DOK1 (rat) KGSDTALYSQVQKSG Y448
S450-p
sHNsALysQVQKSGA
Upstream
Downstream
1 2
Effects on Biological Processes:
  • cell growth, inhibited
  • cell motility, induced
Putative in vivo kinases:
  • IKKB (human)
Regulatory protein:
  • ATM (human)
Treatment
  • anti-TNFalpha
  • ionizing_radiation
DOK1 (human) sHNsALysQVQKSGA S450-p
DOK1 iso3 (human) SHNSALYSQVQKSGA S311
DOK1 (mouse) SSDTALySQVQKSGT S451
DOK1 (rat) GSDTALYSQVQKSGT S449
S458-p
QVQKSGAsGsWDCGL
0 1
DOK1 (human) QVQKSGAsGsWDCGL S458-p
DOK1 iso3 (human) QVQKSGASGSWDCGL S319
DOK1 (mouse) QVQKSGTSGAWDCGL S459
DOK1 (rat) QVQKSGTPGRWDCGL P457
S460-p
QKSGAsGsWDCGLSR
0 6
DOK1 (human) QKSGAsGsWDCGLSR S460-p
DOK1 iso3 (human) QKSGASGSWDCGLSR S321
DOK1 (mouse) QKSGTSGAWDCGLSK A461
DOK1 (rat) QKSGTPGRWDCGLSR R459
T470-p
CGLSRVGtDKTGVKS
0 4
DOK1 (human) CGLSRVGtDKTGVKS T470-p
DOK1 iso3 (human) CGLSRVGTDKTGVKS T331
DOK1 (mouse) CGLSKVGNDRAGVKS N471
DOK1 (rat) CGLSRVGNDRVGVKS N469
T481-p
GVKSEGSt_______
0 1
DOK1 (human) GVKSEGSt_______ T481-p
DOK1 iso3 (human) GVKSEGST_______ T342
DOK1 (mouse) GVKSEGST_______ T482
DOK1 (rat) GVKSEGST_______ T480