Other Species / Isoforms
  AMPKA2 (mouse)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

 HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
K41
EHQLTGHKVAVKILN
0 1
AMPKA2 (human) EHQLTGHkVAVKILN K41-ub
AMPKA2 (mouse) EHQLTGHKVAVKILN K41
AMPKA2 (rat) EHQLTGHKVAVKILN K41
AMPKA2 (pig) EHQLTGHKVAVKILN K41
K60-ub
RSLDVVGkIKREIQN
1 1
AMPKA2 (human) RSLDVVGkIKREIQN K60-ub
AMPKA2 (mouse) RSLDVVGkIKREIQN K60-ub
AMPKA2 (rat) RSLDVVGKIKREIQN K60
AMPKA2 (pig) RSLDVVGKIKREIQN K60
K69-ac
KREIQNLkLFRHPHI
0 4
AMPKA2 (human) KREIQNLkLFRHPHI K69-ac
AMPKA2 (mouse) KREIQNLkLFRHPHI K69-ac
AMPKA2 (rat) KREIQNLkLFRHPHI K69-ac
AMPKA2 (pig) KREIQNLKLFRHPHI K69
S165-p
FGLSNMMsDGEFLRt
0 5
AMPKA2 (human) FGLSNMMsDGEFLRt S165-p
AMPKA2 (mouse) FGLSNMMsDGEFLRt S165-p
AMPKA2 (rat) FGLSNMMSDGEFLRt S165
AMPKA2 (pig) FGLSNMMSDGEFLRt S165
T172-p
sDGEFLRtsCGsPNY
Upstream
Downstream
221 45
AMPKA2 (human)
T172-p
AMPKA2 (mouse)
T172-p
AMPKA2 (rat)
T172-p
Effects on Modified Protein
  • enzymatic activity, induced
  • intracellular localization
  • phosphorylation
  • protein degradation
Effects on Biological Processes:
  • apoptosis, inhibited
  • autophagy, induced
  • autophagy, inhibited
  • carcinogenesis, induced
  • carcinogenesis, inhibited
  • cell differentiation, inhibited
  • cell growth, inhibited
  • cell motility, induced
  • cell motility, inhibited
  • cytoskeletal reorganization
  • signaling pathway regulation
  • transcription, altered
  • transcription, induced
  • transcription, inhibited
Kinase, in vitro:
  • CAMKK2 (human)
Putative in vivo kinases:
  • AMPKA2 (human)
  • CAMKK2 (human)
  • LKB1 (human)
  • RIPK3 (human)
Regulatory protein:
  • ADRB3 (human)
  • AMPKB1 (human)
  • AMPKB2 (human)
  • APRT (human)
  • ASB2 (mouse)
  • ATG14 (human)
  • beclin 1 (human)
  • BMAL1 (human)
  • C1QTNF9 (human)
  • CAMKK1 (mouse)
  • CAPN1 (human)
  • Cas-L (human)
  • CYP4F22 (human)
  • DOK3 (mouse)
  • FAK (human)
  • GLUT1 (mouse)
  • HGK (mouse)
  • HPRT1 (human)
  • IRF3 (human)
  • ITGAV (human)
  • KHK (human)
  • KRas (human)
  • LDH-B (human)
  • LKB1 (human)
  • LKB1 (mouse)
  • PPP2R1B (human)
  • QPRT (human)
  • RIPK3 (human)
  • SCD (mouse)
  • SGK1 (human)
  • SGK1 (mouse)
  • SIRT1 (human)
  • STING (human)
  • TAK1 (mouse)
  • TLR9 (human)
  • ULK1 (human)
  • UMPS (human)
  • UPRT (human)
  • UVRAG (human)
Treatment
  • 2-deoxyglucose
  • 991
  • A-769662
  • A769662
  • acadesine
  • adiponectin
  • allose
  • angiotensin_2
  • anoxia
  • antibody
  • astragaloside_IV
  • bacterial infection
  • benzo(a)pyrene
  • berberine
  • betulinic_acid
  • BI-D1870
  • birinapant
  • caffeine
  • CBU90
  • CBU91
  • chloroquine
  • clozapine
  • colforsin
  • compound_C
  • CYCLOPAMINE
  • DAMGO
  • dantrolene
  • dasatinib
  • electrical_stimulation
  • ESI-09
  • exercise
  • food deprivation
  • fructose
  • galactose
  • glucose
  • glucose_starvation
  • GSK'872
  • H-89
  • H2O2
  • HG9-91-01
  • high-fat diet
  • high_glucose
  • hypoxia
  • IL-11
  • IL-6
  • insulin
  • ischemia
  • ischemia/reperfusion
  • KN-93
  • L-mevalonate
  • leptin
  • leucine_deprivation
  • lncRNAs
  • low_glucose
  • mannose
  • MDL-28170
  • MDL12330A
  • mercaptopurine
  • mesna
  • metformin
  • muscle contraction
  • NAC
  • NTCU
  • obesity-inducing diet
  • ODN2395
  • oligomycin
  • palmitate
  • PDTC
  • Pentadecanoic acid
  • PF 573228
  • PF739
  • phenformin
  • phenylephrine
  • pilocarpine
  • pomegranate_wine
  • pravastatin
  • pterosin_B
  • pyridoxine
  • Q-VD-OPh
  • rapamycin
  • SBI-0206965
  • serum_starvation
  • simvastatin
  • siRNA
  • sorbose
  • SRT1720
  • stiff ECM substrate
  • STO-609
  • SU6656
  • sucrose
  • swim stress
  • TAC
  • tanespimycin
  • telmisartan
  • tempol
  • TGF-beta
  • tideglusib
  • TMZ
  • TNF
  • Trametinib
  • trehalose
  • U73122
  • VAT-R
  • virus infection
  • WR1065
  • Z-VAD-FMK
AMPKA2 (human) sDGEFLRtsCGsPNy T172-p
AMPKA2 (mouse) sDGEFLRtsCGsPNY T172-p
AMPKA2 (rat) SDGEFLRtsCGSPNY T172-p
AMPKA2 (pig) SDGEFLRtSCGSPNY T172-p
S173-p
DGEFLRtsCGsPNYA
2 19
AMPKA2 (human) DGEFLRtsCGsPNyA S173-p
AMPKA2 (mouse) DGEFLRtsCGsPNYA S173-p
AMPKA2 (rat) DGEFLRtsCGSPNYA S173-p
AMPKA2 (pig) DGEFLRtSCGSPNYA S173
S176-p
FLRtsCGsPNYAAPE
0 18
AMPKA2 (human) FLRtsCGsPNyAAPE S176-p
AMPKA2 (mouse) FLRtsCGsPNYAAPE S176-p
AMPKA2 (rat) FLRtsCGSPNYAAPE S176
AMPKA2 (pig) FLRtSCGSPNYAAPE S176
Y179
tsCGsPNYAAPEVIS
1 3
AMPKA2 (human) tsCGsPNyAAPEVIS Y179-p
AMPKA2 (mouse) tsCGsPNYAAPEVIS Y179
AMPKA2 (rat) tsCGSPNYAAPEVIS Y179
AMPKA2 (pig) tSCGSPNYAAPEVIS Y179
R227
PTLFKKIRGGVFYIP
0 1
AMPKA2 (human) PTLFKKIrGGVFyIP R227-m1
AMPKA2 (mouse) PTLFKKIRGGVFYIP R227
AMPKA2 (rat) PTLFKKIRGGVFYIP R227
AMPKA2 (pig) PTLFKKIRGGVFYIP R227
Y232
KIRGGVFYIPDYLNR
0 1
AMPKA2 (human) KIrGGVFyIPEYLNR Y232-p
AMPKA2 (mouse) KIRGGVFYIPDYLNR Y232
AMPKA2 (rat) KIRGGVFYIPEYLNR Y232
AMPKA2 (pig) KIRGGVFYIPEYLNR Y232
T258
VDPLKRATIKDIREH
1 1
AMPKA2 (human) VDPLKRATIKDIREH T258
AMPKA2 (mouse) VDPLKRATIKDIREH T258
AMPKA2 (rat) VDPLKRAtIKDIREH T258-p
AMPKA2 (pig) VDPLKRATIKDIREH T258
K269
IREHEWFKQDLPSYL
0 1
AMPKA2 (human) IREHEWFkQDLPSYL K269-ub
AMPKA2 (mouse) IREHEWFKQDLPSYL K269
AMPKA2 (rat) IREHEWFKQDLPSYL K269
AMPKA2 (pig) IREHEWFKQDLPSYL K269
S310-p
TESEVMNsLYSGDPQ
0 1
AMPKA2 (human) TESEVMNSLYSGDPQ S310
AMPKA2 (mouse) TESEVMNsLYSGDPQ S310-p
AMPKA2 (rat) TESEVMNSLYSGDPQ S310
AMPKA2 (pig) TESEVMNSLYSGDPQ S310
Y324
QDQLAVAYHLIIDNR
0 1
AMPKA2 (human) QDQLAVAyHLIIDNR Y324-p
AMPKA2 (mouse) QDQLAVAYHLIIDNR Y324
AMPKA2 (rat) QDQLAVAYHLIIDNR Y324
AMPKA2 (pig) QDQLAVAYHLVIDNR Y324
S377-p
MPPLIADsPkARCPL
Upstream
0 28
Regulatory protein:
  • ADRB1 (mouse)
AMPKA2 (human) MPPLIADsPkARCPL S377-p
AMPKA2 (mouse) MPPLIADsPkARCPL S377-p
AMPKA2 (rat) MPPLIADsPKARCPL S377-p
AMPKA2 (pig) MPPLIADSPKARCPL S377
K379-ub
PLIADsPkARCPLDA
1 1
AMPKA2 (human) PLIADsPkARCPLDA K379-ub
AMPKA2 (mouse) PLIADsPkARCPLDA K379-ub
AMPKA2 (rat) PLIADsPKARCPLDA K379
AMPKA2 (pig) PLIADSPKARCPLDA K379
K391
LDALNTTKPKSLAVK
1 1
AMPKA2 (human) LDALNTTkPKSLAVK K391-ub
AMPKA2 (mouse) LDALNTTKPKSLAVK K391
AMPKA2 (rat) LDALNTTKPKSLAVK K391
AMPKA2 (pig) LDALNTTKPKSLAVK K391
Y436
EWKVVNAYHLRVRRK
1 0
AMPKA2 (human) EWKVVNAyHLRVRRK Y436-p
AMPKA2 (mouse) EWKVVNAYHLRVRRK Y436
AMPKA2 (rat) EWKVVNAYHLRVRRK Y436
AMPKA2 (pig) EWKVVNAYHLRVRRK Y436
K470-ub
RSYLLDFkSIDDEVV
1 2
AMPKA2 (human) RSYLLDFkSIDDEVV K470-ub
AMPKA2 (mouse) RSYLLDFkSIDDEVV K470-ub
AMPKA2 (rat) RSYLLDFKSIDDEVV K470
AMPKA2 (pig) RSYLLDFKSIDDEVL K470
S481-p
DEVVEQRsGSstPQR
0 6
AMPKA2 (human) DEVVEQRsGsstPQR S481-p
AMPKA2 (mouse) DEVVEQRsGSstPQR S481-p
AMPKA2 (rat) DEVVEQRSGSStPQR S481
AMPKA2 (pig) DEVLEQRSGSSTPQR S481
S483
VVEQRsGSstPQRSC
0 1
AMPKA2 (human) VVEQRsGsstPQRsC S483-p
AMPKA2 (mouse) VVEQRsGSstPQRSC S483
AMPKA2 (rat) VVEQRSGSStPQRSC S483
AMPKA2 (pig) VLEQRSGSSTPQRSC S483
S484-p
VEQRsGSstPQRSCs
1 2
AMPKA2 (human) VEQRsGsstPQRsCs S484-p
AMPKA2 (mouse) VEQRsGSstPQRSCs S484-p
AMPKA2 (rat) VEQRSGSStPQRSCs S484
AMPKA2 (pig) LEQRSGSSTPQRSCS S484
T485-p
EQRsGSstPQRSCsA
Upstream
2 2
Putative in vivo kinases:
  • SGK1 (human)
Treatment
  • insulin
AMPKA2 (human) EQRsGsstPQRsCsA T485-p
AMPKA2 (mouse) EQRsGSstPQRSCsA T485-p
AMPKA2 (rat) EQRSGSStPQRSCsA T485-p
AMPKA2 (pig) EQRSGSSTPQRSCSA T485
S489
GSstPQRSCsAAGLH
0 1
AMPKA2 (human) GsstPQRsCsAAGLH S489-p
AMPKA2 (mouse) GSstPQRSCsAAGLH S489
AMPKA2 (rat) GSStPQRSCsAAGLH S489
AMPKA2 (pig) GSSTPQRSCSAAGLH S489
S491-p
stPQRSCsAAGLHRA
Upstream
Downstream
14 13
AMPKA2 (human)
S491-p
AMPKA2 (rat)
S491-p
Effects on Modified Protein
  • enzymatic activity, inhibited
Kinase, in vitro:
  • SGK1 (human)
Putative in vivo kinases:
  • PRKD1 (human)
  • SGK1 (human)
Treatment
  • CRT0066101
  • Go_6983
  • insulin
  • LY294002
  • MK-2206
  • phorbol_ester
  • rapamycin
  • wortmannin
AMPKA2 (human) stPQRsCsAAGLHRP S491-p
AMPKA2 (mouse) stPQRSCsAAGLHRA S491-p
AMPKA2 (rat) StPQRSCsAAGLHRP S491-p
AMPKA2 (pig) STPQRSCSAAGLHRP S491
S500-p
AGLHRARssFDSSTA
0 3
AMPKA2 (human) AGLHRPRssFDSTTA S500-p
AMPKA2 (mouse) AGLHRARssFDSSTA S500-p
AMPKA2 (rat) AGLHRPRSSVDSSTA S500
AMPKA2 (pig) AGLHRPRSSLDSVTA S500
S501-p
GLHRARssFDSSTAE
0 2
AMPKA2 (human) GLHRPRssFDSTTAE S501-p
AMPKA2 (mouse) GLHRARssFDSSTAE S501-p
AMPKA2 (rat) GLHRPRSSVDSSTAE S501
AMPKA2 (pig) GLHRPRSSLDSVTAE S501
N509
FDSSTAENHSLSGSL
0 1
AMPKA2 (human) FDSTTAEsHsLSGsL S509-p
AMPKA2 (mouse) FDSSTAENHSLSGSL N509
AMPKA2 (rat) VDSSTAENHSLSGSL N509
AMPKA2 (pig) LDSVTAESHSLSGSL S509
S511
SSTAENHSLSGSLTG
0 1
AMPKA2 (human) STTAEsHsLSGsLTG S511-p
AMPKA2 (mouse) SSTAENHSLSGSLTG S511
AMPKA2 (rat) SSTAENHSLSGSLTG S511
AMPKA2 (pig) SVTAESHSLSGSLSG S511
S515
ENHSLSGSLTGSLTG
0 2
AMPKA2 (human) EsHsLSGsLTGSLtG S515-p
AMPKA2 (mouse) ENHSLSGSLTGSLTG S515
AMPKA2 (rat) ENHSLSGSLTGSLTG S515
AMPKA2 (pig) ESHSLSGSLSGSLTG S515
T521
GSLTGSLTGSTLSSA
0 1
AMPKA2 (human) GsLTGSLtGStLSsV T521-p
AMPKA2 (mouse) GSLTGSLTGSTLSSA T521
AMPKA2 (rat) GSLTGSLTGSTLSSA T521
AMPKA2 (pig) GSLSGSLTGSMLPSV T521
T524
TGSLTGSTLSSASPR
0 1
AMPKA2 (human) TGSLtGStLSsVSPR T524-p
AMPKA2 (mouse) TGSLTGSTLSSASPR T524
AMPKA2 (rat) TGSLTGSTLSSASPR T524
AMPKA2 (pig) SGSLTGSMLPSVPPR M524
S527
LTGSTLSSASPRLGS
0 1
AMPKA2 (human) LtGStLSsVSPRLGs S527-p
AMPKA2 (mouse) LTGSTLSSASPRLGS S527
AMPKA2 (rat) LTGSTLSSASPRLGS S527
AMPKA2 (pig) LTGSMLPSVPPRLGS S527
S534
SASPRLGSHTMDFFE
0 1
AMPKA2 (human) sVSPRLGsHTMDFFE S534-p
AMPKA2 (mouse) SASPRLGSHTMDFFE S534
AMPKA2 (rat) SASPRLGSHTMDFFE S534
AMPKA2 (pig) SVPPRLGSHTMDFFE S534