Other Species / Isoforms
  AMPKA2 (mouse)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

  HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
S165
FGLSNMMsDGEFLRt
0 5
AMPKA2 (human) FGLSNMMsDGEFLRt S165
AMPKA2 (mouse) FGLSNMMsDGEFLRt S165
AMPKA2 (rat) FGLSNMMSDGEFLRt S165
AMPKA2 (pig) FGLSNMMSDGEFLRt S165
T172
sDGEFLRtsCGsPNY
Upstream
Downstream
253 46
AMPKA2 (human)
T172
AMPKA2 (mouse)
T172
AMPKA2 (rat)
T172
Effects on Modified Protein
  • enzymatic activity, induced
  • intracellular localization
  • phosphorylation
  • protein degradation
Effects on Biological Processes:
  • apoptosis, inhibited
  • autophagy, induced
  • autophagy, inhibited
  • carcinogenesis, induced
  • carcinogenesis, inhibited
  • cell differentiation, inhibited
  • cell growth, inhibited
  • cell motility, induced
  • cell motility, inhibited
  • cytoskeletal reorganization
  • signaling pathway regulation
  • transcription, altered
  • transcription, induced
  • transcription, inhibited
Kinase, in vitro:
  • CAMKK2 (human)
Putative in vivo kinases:
  • AMPKA2 (human)
  • CAMKK2 (human)
  • LKB1 (human)
  • RIPK3 (human)
view more >
Regulatory protein:
  • ADRB3 (human)
  • AMPKB1 (human)
  • AMPKB2 (human)
  • APRT (human)
  • ASB2 (mouse)
  • ATG14 (human)
  • beclin 1 (human)
  • BMAL1 (human)
  • C1QTNF9 (human)
  • CAMKK1 (mouse)
  • CAPN1 (human)
  • Cas-L (human)
  • caveolin-1 (human)
  • CYP4F22 (human)
  • DGAT1 (mouse)
  • DGAT2 (mouse)
  • DOK3 (mouse)
  • FAK (human)
  • GLUT1 (mouse)
  • HGK (mouse)
  • HPRT1 (human)
  • IRF3 (human)
  • ITGAV (human)
  • KHK (human)
  • KRas (human)
  • LDH-B (human)
  • LKB1 (human)
  • LKB1 (mouse)
  • p16-INK4A (human)
  • P2X7 (mouse)
  • PPP2R1B (human)
  • QPRT (human)
  • RIPK3 (human)
  • SCD (mouse)
  • SGK1 (human)
  • SGK1 (mouse)
  • SIRT1 (human)
  • SOD1 (mouse)
  • STING (human)
  • TAK1 (mouse)
  • TLR9 (human)
  • ULK1 (human)
  • UMPS (human)
  • UPRT (human)
  • UVRAG (human)
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Treatment
  • (E)-3-[3, 4-dihydroxyphenyl-1-(piperidin-1-yl)prop-2-en-1-one]
  • 2-deoxyglucose
  • 991
  • A-769662
  • A769662
  • acadesine
  • adiponectin
  • allose
  • angiotensin_2
  • anoxia
  • antibody
  • astragaloside_IV
  • bacterial infection
  • benzo(a)pyrene
  • berberine
  • betulinic_acid
  • BI-D1870
  • birinapant
  • caffeine
  • calorie_restriction
  • CBU90
  • CBU91
  • chloroquine
  • clozapine
  • colforsin
  • compound_C
  • CYCLOPAMINE
  • DAMGO
  • dantrolene
  • dasatinib
  • development
  • electrical_stimulation
  • enriched environment
  • ESI-09
  • ethanol
  • exercise
  • exercise training
  • food deprivation
  • fructose
  • G-1
  • galactose
  • glucose
  • glucose_starvation
  • GSK'872
  • H-89
  • H2O2
  • HG9-91-01
  • high-fat diet
  • high_glucose
  • hypoxia
  • IL-11
  • IL-6
  • insulin
  • ischemia
  • ischemia/reperfusion
  • isoproterenol
  • kainic_acid
  • KN-93
  • L-mevalonate
  • leptin
  • leucine_deprivation
  • lncRNAs
  • low_glucose
  • LPS
  • mannose
  • MDL-28170
  • MDL12330A
  • mercaptopurine
  • mesna
  • metformin
  • MS275
  • muscle contraction
  • NAC
  • NTCU
  • obesity-inducing diet
  • ODN2395
  • oligomycin
  • palmitate
  • PDTC
  • Pentadecanoic acid
  • PF 573228
  • PF739
  • phenformin
  • phenylephrine
  • pilocarpine
  • pomegranate_wine
  • pravastatin
  • pterosin_B
  • pyridoxine
  • Q-VD-OPh
  • rapamycin
  • resveratrol
  • rosiglitazone
  • SBI-0206965
  • serum_starvation
  • simvastatin
  • siRNA
  • sorbose
  • SRT1720
  • stiff ECM substrate
  • STO-609
  • SU6656
  • sucrose
  • swim stress
  • TAC
  • tanespimycin
  • telmisartan
  • tempol
  • TGF-beta
  • tideglusib
  • TMZ
  • TNF
  • Trametinib
  • trehalose
  • U73122
  • VAT-R
  • vinpocetine
  • virus infection
  • WR1065
  • Z-VAD-FMK
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AMPKA2 (human) sDGEFLRtsCGsPNy T172
AMPKA2 (mouse) sDGEFLRtsCGsPNY T172
AMPKA2 (rat) SDGEFLRtsCGSPNY T172
AMPKA2 (pig) SDGEFLRtSCGSPNY T172
S173
DGEFLRtsCGsPNYA
2 19
AMPKA2 (human) DGEFLRtsCGsPNyA S173
AMPKA2 (mouse) DGEFLRtsCGsPNYA S173
AMPKA2 (rat) DGEFLRtsCGSPNYA S173
AMPKA2 (pig) DGEFLRtSCGSPNYA S173
S176
FLRtsCGsPNYAAPE
0 19
AMPKA2 (human) FLRtsCGsPNyAAPE S176
AMPKA2 (mouse) FLRtsCGsPNYAAPE S176
AMPKA2 (rat) FLRtsCGSPNYAAPE S176
AMPKA2 (pig) FLRtSCGSPNYAAPE S176
Y179
tsCGsPNYAAPEVIS
1 3
AMPKA2 (human) tsCGsPNyAAPEVIS Y179
AMPKA2 (mouse) tsCGsPNYAAPEVIS Y179
AMPKA2 (rat) tsCGSPNYAAPEVIS Y179
AMPKA2 (pig) tSCGSPNYAAPEVIS Y179
Y232
KIRGGVFYIPDYLNR
0 1
AMPKA2 (human) KIRGGVFyIPEYLNR Y232
AMPKA2 (mouse) KIRGGVFYIPDYLNR Y232
AMPKA2 (rat) KIRGGVFYIPEYLNR Y232
AMPKA2 (pig) KIRGGVFYIPEYLNR Y232
T258
VDPLKRATIKDIREH
1 1
AMPKA2 (human) VDPLKRATIKDIREH T258
AMPKA2 (mouse) VDPLKRATIKDIREH T258
AMPKA2 (rat) VDPLKRAtIKDIREH T258
AMPKA2 (pig) VDPLKRATIKDIREH T258
S310
TESEVMNsLYSGDPQ
0 1
AMPKA2 (human) TESEVMNSLYSGDPQ S310
AMPKA2 (mouse) TESEVMNsLYSGDPQ S310
AMPKA2 (rat) TESEVMNSLYSGDPQ S310
AMPKA2 (pig) TESEVMNSLYSGDPQ S310
Y324
QDQLAVAYHLIIDNR
0 1
AMPKA2 (human) QDQLAVAyHLIIDNR Y324
AMPKA2 (mouse) QDQLAVAYHLIIDNR Y324
AMPKA2 (rat) QDQLAVAYHLIIDNR Y324
AMPKA2 (pig) QDQLAVAYHLVIDNR Y324
S345
SEFYLASSPPSGSFM
2 0
AMPKA2 (human)
S345
AMPKA2 (mouse)
S345
AMPKA2 (rat)
S345
AMPKA2 (human) SEFYLASsPPSGSFM S345
AMPKA2 (mouse) SEFYLASSPPSGSFM S345
AMPKA2 (rat) SEFYLASSPPTGSFM S345
AMPKA2 (pig) SEFYLASSPPTGSFM S345
S377
MPPLIADsPKARCPL
Upstream
0 28
Regulatory protein:
  • ADRB1 (mouse)
AMPKA2 (human) MPPLIADsPKARCPL S377
AMPKA2 (mouse) MPPLIADsPKARCPL S377
AMPKA2 (rat) MPPLIADsPKARCPL S377
AMPKA2 (pig) MPPLIADSPKARCPL S377
Y436
EWKVVNAYHLRVRRK
1 0
AMPKA2 (human) EWKVVNAyHLRVRRK Y436
AMPKA2 (mouse) EWKVVNAYHLRVRRK Y436
AMPKA2 (rat) EWKVVNAYHLRVRRK Y436
AMPKA2 (pig) EWKVVNAYHLRVRRK Y436
S481
DEVVEQRsGSstPQR
0 6
AMPKA2 (human) DEVVEQRsGsstPQR S481
AMPKA2 (mouse) DEVVEQRsGSstPQR S481
AMPKA2 (rat) DEVVEQRSGSStPQR S481
AMPKA2 (pig) DEVLEQRSGSSTPQR S481
S483
VVEQRsGSstPQRSC
0 1
AMPKA2 (human) VVEQRsGsstPQRsC S483
AMPKA2 (mouse) VVEQRsGSstPQRSC S483
AMPKA2 (rat) VVEQRSGSStPQRSC S483
AMPKA2 (pig) VLEQRSGSSTPQRSC S483
S484
VEQRsGSstPQRSCs
Upstream
Downstream
2 2
Effects on Modified Protein
  • phosphorylation
Treatment
  • metformin
  • TGF-beta
AMPKA2 (human) VEQRsGsstPQRsCs S484
AMPKA2 (mouse) VEQRsGSstPQRSCs S484
AMPKA2 (rat) VEQRSGSStPQRSCs S484
AMPKA2 (pig) LEQRSGSSTPQRSCS S484
T485
EQRsGSstPQRSCsA
Upstream
2 2
Putative in vivo kinases:
  • SGK1 (human)
Treatment
  • insulin
AMPKA2 (human) EQRsGsstPQRsCsA T485
AMPKA2 (mouse) EQRsGSstPQRSCsA T485
AMPKA2 (rat) EQRSGSStPQRSCsA T485
AMPKA2 (pig) EQRSGSSTPQRSCSA T485
S489
GSstPQRSCsAAGLH
0 1
AMPKA2 (human) GsstPQRsCsAAGLH S489
AMPKA2 (mouse) GSstPQRSCsAAGLH S489
AMPKA2 (rat) GSStPQRSCsAAGLH S489
AMPKA2 (pig) GSSTPQRSCSAAGLH S489
S491
stPQRSCsAAGLHRA
Upstream
Downstream
14 13
AMPKA2 (human)
S491
AMPKA2 (rat)
S491
Effects on Modified Protein
  • enzymatic activity, inhibited
  • intracellular localization
Effects on Biological Processes:
  • apoptosis, inhibited
  • signaling pathway regulation
  • translation, inhibited
Kinase, in vitro:
  • SGK1 (human)
Putative in vivo kinases:
  • PRKD1 (human)
  • SGK1 (human)
Regulatory protein:
  • Akt1 (mouse)
  • Akt2 (mouse)
Treatment
  • ceritinib
  • crizotinib
  • CRT0066101
  • glucose_starvation
  • Go_6983
  • insulin
  • LY294002
  • metformin
  • MK-2206
  • phorbol_ester
  • rapamycin
  • wortmannin
view more >
AMPKA2 (human) stPQRsCsAAGLHRP S491
AMPKA2 (mouse) stPQRSCsAAGLHRA S491
AMPKA2 (rat) StPQRSCsAAGLHRP S491
AMPKA2 (pig) STPQRSCSAAGLHRP S491
S500
AGLHRARssFDSSTA
0 3
AMPKA2 (human) AGLHRPRssFDSTTA S500
AMPKA2 (mouse) AGLHRARssFDSSTA S500
AMPKA2 (rat) AGLHRPRSSVDSSTA S500
AMPKA2 (pig) AGLHRPRSSLDSVTA S500
S501
GLHRARssFDSSTAE
0 2
AMPKA2 (human) GLHRPRssFDSTTAE S501
AMPKA2 (mouse) GLHRARssFDSSTAE S501
AMPKA2 (rat) GLHRPRSSVDSSTAE S501
AMPKA2 (pig) GLHRPRSSLDSVTAE S501
N509
FDSSTAENHSLSGSL
0 1
AMPKA2 (human) FDSTTAEsHsLSGsL S509
AMPKA2 (mouse) FDSSTAENHSLSGSL N509
AMPKA2 (rat) VDSSTAENHSLSGSL N509
AMPKA2 (pig) LDSVTAESHSLSGSL S509
S511
SSTAENHSLSGSLTG
0 1
AMPKA2 (human) STTAEsHsLSGsLTG S511
AMPKA2 (mouse) SSTAENHSLSGSLTG S511
AMPKA2 (rat) SSTAENHSLSGSLTG S511
AMPKA2 (pig) SVTAESHSLSGSLSG S511
S515
ENHSLSGSLTGSLTG
0 2
AMPKA2 (human) EsHsLSGsLTGSLtG S515
AMPKA2 (mouse) ENHSLSGSLTGSLTG S515
AMPKA2 (rat) ENHSLSGSLTGSLTG S515
AMPKA2 (pig) ESHSLSGSLSGSLTG S515
T521
GSLTGSLTGSTLSSA
0 1
AMPKA2 (human) GsLTGSLtGStLSsV T521
AMPKA2 (mouse) GSLTGSLTGSTLSSA T521
AMPKA2 (rat) GSLTGSLTGSTLSSA T521
AMPKA2 (pig) GSLSGSLTGSMLPSV T521
T524
TGSLTGSTLSSASPR
0 1
AMPKA2 (human) TGSLtGStLSsVSPR T524
AMPKA2 (mouse) TGSLTGSTLSSASPR T524
AMPKA2 (rat) TGSLTGSTLSSASPR T524
AMPKA2 (pig) SGSLTGSMLPSVPPR M524
S527
LTGSTLSSASPRLGS
0 1
AMPKA2 (human) LtGStLSsVSPRLGs S527
AMPKA2 (mouse) LTGSTLSSASPRLGS S527
AMPKA2 (rat) LTGSTLSSASPRLGS S527
AMPKA2 (pig) LTGSMLPSVPPRLGS S527
S534
SASPRLGSHTMDFFE
0 1
AMPKA2 (human) sVSPRLGsHTMDFFE S534
AMPKA2 (mouse) SASPRLGSHTMDFFE S534
AMPKA2 (rat) SASPRLGSHTMDFFE S534
AMPKA2 (pig) SVPPRLGSHTMDFFE S534