Other Species / Isoforms
  SERT (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

  HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
S13-p
LNSQKQLsACEDGED
Upstream
1 1
Kinase, in vitro:
  • CAMK2A (human)
SERT (human) LNSQKQLsACEDGED S13-p
SERT iso2 (human) LNSQKQLSACEDGED S55
SERT (mouse) LNSQKVLSECKDKED S13
SERT (rat) LNSQKVLSECKDRED S13
Y47-p
SGQISNGysAVPSPG
Upstream
Downstream
1 1
Effects on Modified Protein
  • activity, induced
  • protein stabilization
Putative in vivo kinases:
  • Src (human)
Treatment
  • PP2
  • siRNA
SERT (human) SGQISNGysAVPSPG Y47-p
SERT iso2 (human) SGQISNGYSAVPSPG Y89
SERT (mouse) PGQISNGYSAVPSTS Y47
SERT (rat) PSQISNGYSAVPSTS Y47
S48-p
GQISNGysAVPSPGA
Upstream
Downstream
1 0
Effects on Modified Protein
  • receptor internalization, inhibited
Putative in vivo kinases:
  • GSK3B (human)
Treatment
  • CHIR99021
  • siRNA
SERT (human) GQISNGysAVPSPGA S48-p
SERT iso2 (human) GQISNGYSAVPSPGA S90
SERT (mouse) GQISNGYSAVPSTSA S48
SERT (rat) SQISNGYSAVPSTSA S48
T59-p
SPGAGDDtRHSIPAT
0 1
SERT (human) SPGAGDDtRHSIPAT T59-p
SERT iso2 (human) SPGAGDDTRHSIPAT T101
SERT (mouse) STSAGDEAPHSTPAA A59
SERT (rat) STSAGDEASHSIPAA A59
T81-p
LHQGEREtWGKKVDF
Downstream
1 0
Effects on Modified Protein
  • protein conformation
SERT (human) LHQGEREtWGKKVDF T81-p
SERT iso2 (human) LHQGERETWGKKVDF T123
SERT (mouse) IHQGERETWGKKMDF T81
SERT (rat) IRQGERETWGKKMDF T81
Y142-p
MELALGQyHRNGCIs
Upstream
Downstream
1 0
Effects on Modified Protein
  • activity, induced
  • protein stabilization
Putative in vivo kinases:
  • Src (human)
Treatment
  • PP2
  • siRNA
SERT (human) MELALGQyHRNGCIs Y142-p
SERT iso2 (human) MELALGQYHRNGCIS Y184
SERT (mouse) MELALGQYHRNGCIS Y142
SERT (rat) MELALGQYHRNGCIS Y142
S149-p
yHRNGCIsIWRKICP
Upstream
1 1
Kinase, in vitro:
  • PKCA (human)
SERT (human) yHRNGCIsIWRKICP S149-p
SERT iso2 (human) YHRNGCISIWRKICP S191
SERT (mouse) YHRNGCISIWKKICP S149
SERT (rat) YHRNGCISIWRKICP S149
T276-p
SIWKGVKtsGKVVWV
Upstream
Downstream
7 1
Effects on Modified Protein
  • activity, induced
  • protein conformation
Kinase, in vitro:
  • PKG1 (human)
Putative in vivo kinases:
  • PKG1 (human)
Treatment
  • 5-HT
  • 8pCPT-cGMP
  • cGMP_analog
  • cocaine
  • ibogaine
  • NECA
  • NMDG
  • Rp-8pCPT-cGMPS
  • Rp-cGMP
  • SNAP
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SERT (human) SIWKGVKtsGKVVWV T276-p
SERT iso2 (human) SIWKGVKTSGKVVWV T318
SERT (mouse) SIWKGVKTSGKVVWV T276
SERT (rat) SIWKGVKTSGKVVWV T276
S277-p
IWKGVKtsGKVVWVT
Upstream
1 1
Kinase, in vitro:
  • PKCA (human)
SERT (human) IWKGVKtsGKVVWVT S277-p
SERT iso2 (human) IWKGVKTSGKVVWVT S319
SERT (mouse) IWKGVKTSGKVVWVT S277
SERT (rat) IWKGVKTSGKVVWVT S277
T603-p
RLIITPGtFKERIIK
Upstream
1 2
Kinase, in vitro:
  • PKCA (human)
SERT (human) RLIITPGtFKERIIK T603-p
SERT iso2 (human) RLIITPGTFKERIIK T645
SERT (mouse) RLISTPGTLKERIIK T603
SERT (rat) RLISTPGTLKERIIK T603
S611-p
FKERIIKsItPEtPT
Downstream
1 1
Effects on Modified Protein
  • activity, induced
  • molecular association, regulation
SERT (human) FKERIIKsItPEtPT S611-p
SERT iso2 (human) FKERIIKSITPETPT S653
SERT (mouse) LKERIIKSITPETPT S611
SERT (rat) LKERIIKSITPETPT S611
T613-p
ERIIKsItPEtPTEI
Downstream
1 1
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
SERT (human) ERIIKsItPEtPTEI T613-p
SERT iso2 (human) ERIIKSITPETPTEI T655
SERT (mouse) ERIIKSITPETPTEI T613
SERT (rat) ERIIKSITPETPTEI T613
T616-p
IKsItPEtPTEIPCG
Upstream
Downstream
2 1
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
Kinase, in vitro:
  • ERK1 (human)
  • ERK2 (human)
  • JNK2 (human)
  • P38A (human)
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SERT (human) IKsItPEtPTEIPCG T616-p
SERT iso2 (human) IKSITPETPTEIPCG T658
SERT (mouse) IKSITPETPTEIPCG T616
SERT (rat) IKSITPETPTEIPCG T616