Other Species / Isoforms
  SMPD3 (mouse)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

 HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
K116-ub
AALLSEWkGTGAGKS
0 1
SMPD3 (human) AALLSEWKGTGPGKS K116
SMPD3 (mouse) AALLSEWkGTGAGKS K116-ub
SMPD3 (rat) AALLSEWKGTGAGKS K116
Y170-p
ARPQIKIyIDsPtNT
0 1
SMPD3 (human) ARPQIKIYIDSPTNT Y170
SMPD3 (mouse) ARPQIKIyIDsPtNT Y170-p
SMPD3 (rat) ARPQIKIYIDSPTNT Y170
S173-p
QIKIyIDsPtNTsIS
Upstream
Downstream
1 2
Effects on Modified Protein
  • enzymatic activity, induced
Treatment
  • H2O2
SMPD3 (human) QIKIYIDSPTNTSIS S173
SMPD3 (mouse) QIKIyIDsPtNTsIS S173-p
SMPD3 (rat) QIKIYIDSPTNTSIS S173
T175-p
KIyIDsPtNTsISAA
0 1
SMPD3 (human) KIYIDSPTNTSISAA T175
SMPD3 (mouse) KIyIDsPtNTsISAA T175-p
SMPD3 (rat) KIYIDSPTNTSISAA T175
S178-p
IDsPtNTsISAAsFs
0 1
SMPD3 (human) IDSPTNTSISAASFS S178
SMPD3 (mouse) IDsPtNTsISAAsFs S178-p
SMPD3 (rat) IDSPTNTSISAASFS S178
S183-p
NTsISAAsFssLVSP
0 1
SMPD3 (human) NTSISAASFSSLVSP S183
SMPD3 (mouse) NTsISAAsFssLVSP S183-p
SMPD3 (rat) NTSISAASFSSLVSP S183
S185-p
sISAAsFssLVSPQG
0 1
SMPD3 (human) SISAASFSSLVSPQG S185
SMPD3 (mouse) sISAAsFssLVSPQG S185-p
SMPD3 (rat) SISAASFSSLVSPQG S185
S186-p
ISAAsFssLVSPQGG
0 3
SMPD3 (human) ISAASFSSLVSPQGG S186
SMPD3 (mouse) ISAAsFssLVSPQGG S186-p
SMPD3 (rat) ISAASFSSLVSPQGS S186
S202-p
GSRAVPGsIKRTAsV
0 5
SMPD3 (human) VARAVPGsIKRTAsV S203-p
SMPD3 (mouse) GSRAVPGsIKRTAsV S202-p
SMPD3 (rat) GARAVPGsIKRTAsV S202-p
S208-p
GsIKRTAsVEYKGDG
Upstream
Downstream
1 7
Effects on Modified Protein
  • protein stabilization
Treatment
  • H2O2
SMPD3 (human) GsIKRTAsVEyKGDG S209-p
SMPD3 (mouse) GsIKRTAsVEYKGDG S208-p
SMPD3 (rat) GsIKRTAsVEYKGDG S208-p
Y211
KRTAsVEYKGDGGRH
0 1
SMPD3 (human) KRTAsVEyKGDGGRH Y212-p
SMPD3 (mouse) KRTAsVEYKGDGGRH Y211
SMPD3 (rat) KRTAsVEYKGDGGRH Y211
S236-p
SGEQADGsLEDSCIV
0 3
SMPD3 (human) SGDPVDSSSPEDACI S237
SMPD3 (mouse) SGEQADGsLEDSCIV S236-p
SMPD3 (rat) SGEQADGsLEDSCIV S236-p
T272-p
ARNGAGGtPKGQtPN
Upstream
0 1
Treatment
  • LPA
SMPD3 (human) ARNGAGGGPRGQtPN G274
SMPD3 (mouse) ARNGAGGtPKGQtPN T272-p
SMPD3 (rat) ARNGAGGTPKGQTPN T272
T277-p
GGtPKGQtPNHNQRD
0 2
SMPD3 (human) GGGPRGQtPNHNQQD T279-p
SMPD3 (mouse) GGtPKGQtPNHNQRD T277-p
SMPD3 (rat) GGTPKGQTPNHNQRD T277
S287-p
HNQRDGDsGsLGsPs
Upstream
0 1
Regulatory protein:
  • TSC2 (mouse)
SMPD3 (human) HNQQDGDSGsLGSPS S289
SMPD3 (mouse) HNQRDGDsGsLGsPs S287-p
SMPD3 (rat) HNQRDGDSGsLGsPs S287
S289-p
QRDGDsGsLGsPsAs
Upstream
Downstream
1 14
Effects on Modified Protein
  • enzymatic activity, induced
  • protein stabilization
Regulatory protein:
  • TSC2 (mouse)
Treatment
  • H2O2
SMPD3 (human) QQDGDSGsLGSPSAS S291-p
SMPD3 (mouse) QRDGDsGsLGsPsAs S289-p
SMPD3 (rat) QRDGDSGsLGsPsAS S289-p
S292-p
GDsGsLGsPsAsREs
Upstream
Downstream
1 13
Effects on Modified Protein
  • enzymatic activity, induced
  • protein stabilization
Regulatory protein:
  • TSC2 (mouse)
Treatment
  • H2O2
SMPD3 (human) GDSGsLGSPSASRES S294
SMPD3 (mouse) GDsGsLGsPsAsREs S292-p
SMPD3 (rat) GDSGsLGsPsASRES S292-p
S294-p
sGsLGsPsAsREsLV
Upstream
0 5
Regulatory protein:
  • TSC2 (mouse)
SMPD3 (human) SGsLGSPSASRESLV S296
SMPD3 (mouse) sGsLGsPsAsREsLV S294-p
SMPD3 (rat) SGsLGsPsASRESLV S294-p
S296-p
sLGsPsAsREsLVKA
Upstream
0 5
Regulatory protein:
  • TSC2 (mouse)
SMPD3 (human) sLGSPSASRESLVKG S298
SMPD3 (mouse) sLGsPsAsREsLVKA S296-p
SMPD3 (rat) sLGsPsASRESLVKA S296
S299-p
sPsAsREsLVKARAG
Upstream
Downstream
1 8
Effects on Modified Protein
  • enzymatic activity, induced
  • protein stabilization
Regulatory protein:
  • TSC2 (mouse)
Treatment
  • H2O2
SMPD3 (human) SPSASRESLVKGRAG S301
SMPD3 (mouse) sPsAsREsLVKARAG S299-p
SMPD3 (rat) sPsASRESLVKARAG S299
K324-ub
ANSKLLYktsVVKKA
0 1
SMPD3 (human) ANSKLLYKAsVVKKA K326
SMPD3 (mouse) ANSKLLYktsVVKKA K324-ub
SMPD3 (rat) SNSKLLYKTsVVKKA K324
T325-p
NSKLLYktsVVKKAA
Upstream
0 1
Treatment
  • LPA
SMPD3 (human) NSKLLYKAsVVKKAA A327
SMPD3 (mouse) NSKLLYktsVVKKAA T325-p
SMPD3 (rat) NSKLLYKTsVVKKAA T325
S326-p
SKLLYktsVVKKAAA
Upstream
0 10
Treatment
  • LPA
SMPD3 (human) SKLLYKAsVVKKAAA S328-p
SMPD3 (mouse) SKLLYktsVVKKAAA S326-p
SMPD3 (rat) SKLLYKTsVVKKAAA S326-p
K433
SFDALASKGALFLKV
0 1
SMPD3 (human) NDDALASkGALFLKV K435-ub
SMPD3 (mouse) SFDALASKGALFLKV K433
SMPD3 (rat) SFDALASKGALFLKV K433
K586-ub
YLAFPTSksPGAGQK
0 1
SMPD3 (human) YLAFPTSKSSGQKGR K588
SMPD3 (mouse) YLAFPTSksPGAGQK K586-ub
SMPD3 (rat) YLAFPTSKSPGAGQK K586
S587-p
LAFPTSksPGAGQKG
0 1
SMPD3 (human) LAFPTSKSSGQKGRK S589
SMPD3 (mouse) LAFPTSksPGAGQKG S587-p
SMPD3 (rat) LAFPTSKSPGAGQKG S587