Other Species / Isoforms
  PCNA (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

 HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
R5-m1
___MFEArLVQGsIL
0 1
PCNA (human) ___MFEArLVQGsIL R5-m1
PCNA (mouse) ___MFEARLIQGSIL R5
PCNA (rat) ___MFEARLIQGSIL R5
PCNA (chicken) ___MFEARLVQGSVL R5
S10-p
EArLVQGsILkkVLE
0 1
PCNA (human) EArLVQGsILkkVLE S10-p
PCNA (mouse) EARLIQGSILKKVLE S10
PCNA (rat) EARLIQGSILKKVLE S10
PCNA (chicken) EARLVQGSVLKRVLE S10
K13-ub
LVQGsILkkVLEALK
0 6
PCNA (human) LVQGsILkkVLEALK K13-ub
PCNA (mouse) LIQGSILKKVLEALK K13
PCNA (rat) LIQGSILKKVLEALK K13
PCNA (chicken) LVQGSVLKRVLEALK K13
K13-sc
LVQGsILkkVLEALK
0 1
PCNA (human) LVQGsILkkVLEALK K13-sc
PCNA (mouse) LIQGSILKKVLEALK K13
PCNA (rat) LIQGSILKKVLEALK K13
PCNA (chicken) LVQGSVLKRVLEALK K13
K13-ac
LVQGsILkkVLEALK
0 1
PCNA (human) LVQGsILkkVLEALK K13-ac
PCNA (mouse) LIQGSILKKVLEALK K13
PCNA (rat) LIQGSILKKVLEALK K13
PCNA (chicken) LVQGSVLKRVLEALK K13
K14-ub
VQGsILkkVLEALKD
0 6
PCNA (human) VQGsILkkVLEALKD K14-ub
PCNA (mouse) IQGSILKKVLEALKD K14
PCNA (rat) IQGSILKKVLEALKD K14
PCNA (chicken) VQGSVLKRVLEALKD R14
Y60-p
RSEGFDTyrCDRNLA
Upstream
Downstream
1 1
Effects on Modified Protein
  • ubiquitination
Effects on Biological Processes:
  • cell cycle regulation
Kinase, in vitro:
  • IGF1R (human)
Putative in vivo kinases:
  • IGF1R (human)
PCNA (human) RSEGFDTyrCDRNLA Y60-p
PCNA (mouse) RSEGFDTYRCDRNLA Y60
PCNA (rat) RSEGFDTYRCDRNLA Y60
PCNA (chicken) RSEGFDTYRCDRNIA Y60
R61-m1
SEGFDTyrCDRNLAM
0 1
PCNA (human) SEGFDTyrCDRNLAM R61-m1
PCNA (mouse) SEGFDTYRCDRNLAM R61
PCNA (rat) SEGFDTYRCDRNLAM R61
PCNA (chicken) SEGFDTYRCDRNIAM R61
K77-ac
VNLTSMSkILkCAGN
0 2
PCNA (human) VNLTSMSkILkCAGN K77-ac
PCNA (mouse) VNLTSMSKILkCAGN K77
PCNA (rat) VNLTSMSKILKCAGN K77
PCNA (chicken) VNLNSMSKILKCAGN K77
K77-ub
VNLTSMSkILkCAGN
0 16
PCNA (human) VNLTSMSkILkCAGN K77-ub
PCNA (mouse) VNLTSMSKILkCAGN K77
PCNA (rat) VNLTSMSKILKCAGN K77
PCNA (chicken) VNLNSMSKILKCAGN K77
K80-ac
TSMSkILkCAGNEDI
0 18
PCNA (human) TSMSkILkCAGNEDI K80-ac
PCNA (mouse) TSMSKILKCAGNEDI K80
PCNA (rat) TSMSKILKCAGNEDI K80
PCNA (chicken) NSMSKILKCAGNEDI K80
K80-ub
TSMSkILkCAGNEDI
0 38
PCNA (human) TSMSkILkCAGNEDI K80-ub
PCNA (mouse) TSMSKILkCAGNEDI K80-ub
PCNA (rat) TSMSKILKCAGNEDI K80
PCNA (chicken) NSMSKILKCAGNEDI K80
K110-ub
FEAPNQEkVSDyEMk
0 14
PCNA (human) FEAPNQEkVSDyEMk K110-ub
PCNA (mouse) FEAPNQEKVSDyEMk K110
PCNA (rat) FEAPNQEKVSDYEMK K110
PCNA (chicken) FEAPNQEKVSDYEMK K110
Y114-p
NQEkVSDyEMkLMDL
2 2
PCNA (human) NQEkVSDyEMkLMDL Y114-p
PCNA (mouse) NQEKVSDyEMkLMDL Y114-p
PCNA (rat) NQEKVSDYEMKLMDL Y114
PCNA (chicken) NQEKVSDYEMKLMDL Y114
K117-ub
kVSDyEMkLMDLDVE
0 9
PCNA (human) kVSDyEMkLMDLDVE K117-ub
PCNA (mouse) KVSDyEMkLMDLDVE K117-ub
PCNA (rat) KVSDYEMKLMDLDVE K117
PCNA (chicken) KVSDYEMKLMDLDVE K117
Y133-p
LGIPEQEysCVVkMP
Upstream
Downstream
1 1
Effects on Modified Protein
  • ubiquitination
Effects on Biological Processes:
  • cell cycle regulation
Kinase, in vitro:
  • IGF1R (human)
Putative in vivo kinases:
  • IGF1R (human)
PCNA (human) LGIPEQEysCVVkMP Y133-p
PCNA (mouse) LGIPEQEYSCVIKMP Y133
PCNA (rat) LGIPEQEYSCVVKMP Y133
PCNA (chicken) LGIPEQEYSCVVKMP Y133
S134-p
GIPEQEysCVVkMPS
0 1
PCNA (human) GIPEQEysCVVkMPS S134-p
PCNA (mouse) GIPEQEYSCVIKMPS S134
PCNA (rat) GIPEQEYSCVVKMPS S134
PCNA (chicken) GIPEQEYSCVVKMPS S134
K138-ub
QEysCVVkMPSGEFA
0 3
PCNA (human) QEysCVVkMPSGEFA K138-ub
PCNA (mouse) QEYSCVIKMPSGEFA K138
PCNA (rat) QEYSCVVKMPSGEFA K138
PCNA (chicken) QEYSCVVKMPSAEFA K138
R146-m1
MPSGEFArICRDLsH
0 1
PCNA (human) MPSGEFArICRDLsH R146-m1
PCNA (mouse) MPSGEFARICRDLSH R146
PCNA (rat) MPSGEFARICRDLSH R146
PCNA (chicken) MPSAEFARICRDLSH R146
S152-p
ArICRDLsHIGDAVV
0 1
PCNA (human) ArICRDLsHIGDAVV S152-p
PCNA (mouse) ARICRDLSHIGDAVV S152
PCNA (rat) ARICRDLSHIGDAVV S152
PCNA (chicken) ARICRDLSHIGDAVV S152
S161-p
IGDAVVIsCAkDGVk
0 1
PCNA (human) IGDAVVIsCAkDGVk S161-p
PCNA (mouse) IGDAVVISCAkNGVk S161
PCNA (rat) IGDAVVISCAKDGVK S161
PCNA (chicken) IGDAVVISCAkDGVK S161
K164-ub
AVVIsCAkDGVkFSA
Upstream
Downstream
32 148
PCNA (human)
K164-ub
Effects on Modified Protein
  • molecular association, regulation
  • protein degradation
  • ubiquitination
Effects on Biological Processes:
  • DNA repair, altered
  • DNA repair, induced
  • DNA repair, inhibited
  • apoptosis, induced
  • apoptosis, inhibited
  • carcinogenesis, inhibited
  • cell cycle regulation
  • cell growth, inhibited
  • signaling pathway regulation
Regulatory protein:
  • BRCA1 (human)
  • CUL4A (human)
  • CUL4B (human)
  • DCLRE1A (human)
  • DDB1 (human)
  • RAD18 (human)
  • RAD18 (mouse)
  • RECQL5 (human)
  • SHPRH (human)
  • SMARCA3 (human)
Treatment
  • AG1478
  • amphidicolin
  • arginine deprivation
  • AzaC
  • AZD5363
  • CE-WIB801C
  • chlormethine
  • cisplatin
  • hydroxyurea
  • ionizing_radiation
  • MK-2206
  • MMS
  • siRNA
  • UV
  • UVC
  • vorinostat
PCNA (human) AVVIsCAkDGVkFSA K164-ub
PCNA (mouse) AVVISCAkNGVkFSA K164-ub
PCNA (rat) AVVISCAKDGVKFSA K164
PCNA (chicken) AVVISCAkDGVKFSA K164-ub
K164-sm
AVVIsCAkDGVkFSA
Upstream
Downstream
3 2
Effects on Biological Processes:
  • DNA repair, altered
Treatment
  • MMS
PCNA (human) AVVIsCAkDGVkFSA K164-sm
PCNA (mouse) AVVISCAKNGVkFSA K164
PCNA (rat) AVVISCAKDGVKFSA K164
PCNA (chicken) AVVISCAKDGVKFSA K164
K164-sc
AVVIsCAkDGVkFSA
0 1
PCNA (human) AVVIsCAkDGVkFSA K164-sc
PCNA (mouse) AVVISCAKNGVkFSA K164
PCNA (rat) AVVISCAKDGVKFSA K164
PCNA (chicken) AVVISCAKDGVKFSA K164
K164-ac
AVVIsCAkDGVkFSA
0 2
PCNA (human) AVVIsCAkDGVkFSA K164-ac
PCNA (mouse) AVVISCAKNGVkFSA K164
PCNA (rat) AVVISCAKDGVKFSA K164
PCNA (chicken) AVVISCAKDGVKFSA K164
K168-ub
sCAkDGVkFSASGEL
0 22
PCNA (human) sCAkDGVkFSASGEL K168-ub
PCNA (mouse) SCAkNGVkFSASGEL K168-ub
PCNA (rat) SCAKDGVKFSASGEL K168
PCNA (chicken) SCAkDGVKFSANGEL K168
K168-ac
sCAkDGVkFSASGEL
0 1
PCNA (human) sCAkDGVkFSASGEL K168-ac
PCNA (mouse) SCAkNGVKFSASGEL K168
PCNA (rat) SCAKDGVKFSASGEL K168
PCNA (chicken) SCAkDGVKFSANGEL K168
K181-ub
ELGNGNIkLSQTSNV
0 2
PCNA (human) ELGNGNIkLSQTSNV K181-ub
PCNA (mouse) ELGNGNIKLSQTSNV K181
PCNA (rat) ELGNGNIKLSQTSNV K181
PCNA (chicken) ELGNGNIKLSQTSNV K181
K190-ac
SQTSNVDkEEEAVTI
0 1
PCNA (human) SQTSNVDkEEEAVTI K190-ac
PCNA (mouse) SQTSNVDKEEEAVTI K190
PCNA (rat) SQTSNVDKEEEAVSI K190
PCNA (chicken) SQTSNVDKEEEAVTI K190
R210-m1
VQLTFALryLNFFtk
0 1
PCNA (human) VQLTFALryLNFFtk R210-m1
PCNA (mouse) VHLTFALRyLNFFTk R210
PCNA (rat) VQLTFALRYLNFFTK R210
PCNA (chicken) VQLTFALRYLNFFTK R210
Y211-p
QLTFALryLNFFtkA
Upstream
Downstream
6 4
Effects on Modified Protein
  • molecular association, regulation
  • protein stabilization
  • ubiquitination
Effects on Biological Processes:
  • DNA repair, inhibited
  • carcinogenesis, induced
  • cell growth, induced
Kinase, in vitro:
  • EGFR (human)
Putative in vivo kinases:
  • EGFR (human)
Regulatory protein:
  • WHSC1L1 (human)
Treatment
  • AG1478
  • EGF
  • lapatinib
PCNA (human) QLTFALryLNFFtkA Y211-p
PCNA (mouse) HLTFALRyLNFFTkA Y211-p
PCNA (rat) QLTFALRYLNFFTKA Y211
PCNA (chicken) QLTFALRYLNFFTKA Y211
T216-p
LryLNFFtkATPLSS
0 1
PCNA (human) LryLNFFtkATPLSS T216-p
PCNA (mouse) LRyLNFFTkATPLSP T216
PCNA (rat) LRYLNFFTKATPLSP T216
PCNA (chicken) LRYLNFFTKATPLSP T216
K217-ac
ryLNFFtkATPLSST
0 1
PCNA (human) ryLNFFtkATPLSST K217-ac
PCNA (mouse) RyLNFFTKATPLSPT K217
PCNA (rat) RYLNFFTKATPLSPT K217
PCNA (chicken) RYLNFFTKATPLSPT K217
K217
ryLNFFtKATPLSST
0 2
PCNA (human) ryLNFFtKATPLSST K217
PCNA (mouse) RyLNFFTkATPLSPT K217-ub
PCNA (rat) RYLNFFTKATPLSPT K217
PCNA (chicken) RYLNFFTKATPLSPT K217
K248-ub
IADMGHLkYyLAPkI
0 101
PCNA (human) IADMGHLkYyLAPkI K248-ub
PCNA (mouse) IADMGHLkYYLAPKI K248-ub
PCNA (rat) IADMGHLKYYLAPKI K248
PCNA (chicken) IADMGHLKYYLAPKI K248
K248-ac
IADMGHLkYyLAPkI
0 3
PCNA (human) IADMGHLkYyLAPkI K248-ac
PCNA (mouse) IADMGHLKYYLAPKI K248
PCNA (rat) IADMGHLKYYLAPKI K248
PCNA (chicken) IADMGHLKYYLAPKI K248
K248-me
IADMGHLkYyLAPkI
Upstream
Downstream
1 0
Effects on Modified Protein
  • molecular association, regulation
  • protein stabilization
  • ubiquitination
Effects on Biological Processes:
  • DNA repair, induced
  • carcinogenesis, induced
  • cell cycle regulation
  • cell growth, induced
Treatment
  • siRNA
PCNA (human) IADMGHLkYyLAPkI K248-me
PCNA (mouse) IADMGHLKYYLAPKI K248
PCNA (rat) IADMGHLKYYLAPKI K248
PCNA (chicken) IADMGHLKYYLAPKI K248
Y250-p
DMGHLkYyLAPkIED
Upstream
Downstream
1 1
Effects on Modified Protein
  • ubiquitination
Effects on Biological Processes:
  • cell cycle regulation
Kinase, in vitro:
  • IGF1R (human)
Putative in vivo kinases:
  • IGF1R (human)
PCNA (human) DMGHLkYyLAPkIED Y250-p
PCNA (mouse) DMGHLkYYLAPKIED Y250
PCNA (rat) DMGHLKYYLAPKIED Y250
PCNA (chicken) DMGHLKYYLAPKIED Y250
K254-ub
LkYyLAPkIEDEEGs
0 10
PCNA (human) LkYyLAPkIEDEEGs K254-ub
PCNA (mouse) LkYYLAPKIEDEEAS K254
PCNA (rat) LKYYLAPKIEDEEGS K254
PCNA (chicken) LKYYLAPKIEDQQEG K254
K254-sm
LkYyLAPkIEDEEGs
0 3
PCNA (human) LkYyLAPkIEDEEGs K254-sm
PCNA (mouse) LkYYLAPKIEDEEAS K254
PCNA (rat) LKYYLAPKIEDEEGS K254
PCNA (chicken) LKYYLAPKIEDQQEG K254
S261-p
kIEDEEGs_______
0 6
PCNA (human) kIEDEEGs_______ S261-p
PCNA (mouse) KIEDEEAS_______ S261
PCNA (rat) KIEDEEGS_______ S261
PCNA (chicken) IEDQQEGS_______ S262