Other Species / Isoforms
  TLK1 (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

  HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
S20
PPSWSQLSTsPTPGS
0 3
TLK1 (human) PPSWSQLSTsPTPGS S20
TLK1 iso2 (human) PPSWSQLSTSPTPGS S20
TLK1 iso4 (human) gap -
TLK1 (mouse) PPSWSRLstsPtPGS S20-p
TLK1 (rat) PPSWSRLSTSPTPGS S20
T21
PSWSQLSTsPTPGSA
0 1
TLK1 (human) PSWSQLSTsPTPGSA T21
TLK1 iso2 (human) PSWSQLSTSPTPGSA T21
TLK1 iso4 (human) gap -
TLK1 (mouse) PSWSRLstsPtPGSA T21-p
TLK1 (rat) PSWSRLSTSPTPGSA T21
S22-p
SWSQLSTsPTPGSAA
0 10
TLK1 (human) SWSQLSTsPTPGSAA S22-p
TLK1 iso2 (human) SWSQLSTSPTPGSAA S22
TLK1 iso4 (human) gap -
TLK1 (mouse) SWSRLstsPtPGSAA S22-p
TLK1 (rat) SWSRLSTSPTPGSAA S22
T24
SQLSTsPTPGSAAAA
0 2
TLK1 (human) SQLSTsPTPGSAAAA T24
TLK1 iso2 (human) SQLSTSPTPGSAAAA T24
TLK1 iso4 (human) gap -
TLK1 (mouse) SRLstsPtPGSAAAA T24-p
TLK1 (rat) SRLSTSPTPGSAAAA T24
S33-p
GSAAAARsLLNHtPP
0 3
TLK1 (human) GSAAAARsLLNHtPP S33-p
TLK1 iso2 (human) GSAAAARSLLNHTPP S33
TLK1 iso4 (human) gap -
TLK1 (mouse) GSAAAARSLLNHtPP S33
TLK1 (rat) GSAAAARSLLNHTPP S33
T38-p
ARsLLNHtPPsGRPR
0 12
TLK1 (human) ARsLLNHtPPsGRPR T38-p
TLK1 iso2 (human) ARSLLNHTPPSGRPR T38
TLK1 iso4 (human) gap -
TLK1 (mouse) ARSLLNHtPPSGRPR T38-p
TLK1 (rat) ARSLLNHTPPSGRPR T38
S41-p
LLNHtPPsGRPREGA
0 1
TLK1 (human) LLNHtPPsGRPREGA S41-p
TLK1 iso2 (human) LLNHTPPSGRPREGA S41
TLK1 iso4 (human) gap -
TLK1 (mouse) LLNHtPPSGRPREGA S41
TLK1 (rat) LLNHTPPSGRPREGA S41
S54-p
GAMDELHsLDPRRQE
0 2
TLK1 (human) GAMDELHsLDPRRQE S54-p
TLK1 iso2 (human) GAMDELHSLDPRRQE S54
TLK1 iso4 (human) gap -
TLK1 (mouse) GAMDELHSLDPRRQE S54
TLK1 (rat) GAMDELHSLDPRRQE S54
T68-p
ELLEARFtGVAsGsT
0 2
TLK1 (human) ELLEARFtGVAsGsT T68-p
TLK1 iso2 (human) ELLEARFTGVASGST T68
TLK1 iso4 (human) gap -
TLK1 (mouse) ELLEARFtGVATGsT T68-p
TLK1 (rat) ELLEARFTGVATGST T68
S72-p
ARFtGVAsGsTGstG
0 1
TLK1 (human) ARFtGVAsGsTGstG S72-p
TLK1 iso2 (human) ARFTGVASGSTGSTG S72
TLK1 iso4 (human) gap -
TLK1 (mouse) ARFtGVATGsTGStG T72
TLK1 (rat) ARFTGVATGSTGSTG T72
S74-p
FtGVAsGsTGstGsC
0 6
TLK1 (human) FtGVAsGsTGstGsC S74-p
TLK1 iso2 (human) FTGVASGSTGSTGSC S74
TLK1 iso4 (human) gap -
TLK1 (mouse) FtGVATGsTGStGsC S74-p
TLK1 (rat) FTGVATGSTGSTGSC S74
S77-p
VAsGsTGstGsCsVG
0 3
TLK1 (human) VAsGsTGstGsCsVG S77-p
TLK1 iso2 (human) VASGSTGSTGSCSVG S77
TLK1 iso4 (human) gap -
TLK1 (mouse) VATGsTGStGsCsVG S77
TLK1 (rat) VATGSTGSTGSCSVG S77
T78-p
AsGsTGstGsCsVGA
0 2
TLK1 (human) AsGsTGstGsCsVGA T78-p
TLK1 iso2 (human) ASGSTGSTGSCSVGA T78
TLK1 iso4 (human) gap -
TLK1 (mouse) ATGsTGStGsCsVGA T78-p
TLK1 (rat) ATGSTGSTGSCSVGA T78
S80-p
GsTGstGsCsVGAKA
0 2
TLK1 (human) GsTGstGsCsVGAKA S80-p
TLK1 iso2 (human) GSTGSTGSCSVGAKA S80
TLK1 iso4 (human) gap -
TLK1 (mouse) GsTGStGsCsVGAKA S80-p
TLK1 (rat) GSTGSTGSCSVGAKA S80
S82-p
TGstGsCsVGAKASt
Upstream
0 4
Treatment
  • selumetinib
  • vemurafenib
TLK1 (human) TGstGsCsVGAKASt S82-p
TLK1 iso2 (human) TGSTGSCSVGAKAST S82
TLK1 iso4 (human) gap -
TLK1 (mouse) TGStGsCsVGAKAST S82-p
TLK1 (rat) TGSTGSCSVGAKAST S82
T89-p
sVGAKAStNNEssNH
0 1
TLK1 (human) sVGAKAStNNEssNH T89-p
TLK1 iso2 (human) SVGAKASTNNESSNH T89
TLK1 iso4 (human) gap -
TLK1 (mouse) sVGAKASTNNESSNH T89
TLK1 (rat) SVGAKASTNNESSNH T89
S93-p
KAStNNEssNHsFGs
0 4
TLK1 (human) KAStNNEssNHsFGs S93-p
TLK1 iso2 (human) KASTNNESSNHSFGS S93
TLK1 iso4 (human) gap -
TLK1 (mouse) KASTNNESSNHSFGS S93
TLK1 (rat) KASTNNESSNHSFGS S93
S94-p
AStNNEssNHsFGsL
0 3
TLK1 (human) AStNNEssNHsFGsL S94-p
TLK1 iso2 (human) ASTNNESSNHSFGSL S94
TLK1 iso4 (human) gap -
TLK1 (mouse) ASTNNESSNHSFGSL S94
TLK1 (rat) ASTNNESSNHSFGSL S94
S97-p
NNEssNHsFGsLGsL
0 3
TLK1 (human) NNEssNHsFGsLGsL S97-p
TLK1 iso2 (human) NNESSNHSFGSLGSL S97
TLK1 iso4 (human) gap -
TLK1 (mouse) NNESSNHSFGSLGSL S97
TLK1 (rat) NNESSNHSFGSLGSL S97
S100-p
ssNHsFGsLGsLsDK
0 1
TLK1 (human) ssNHsFGsLGsLsDK S100-p
TLK1 iso2 (human) SSNHSFGSLGSLSDK S100
TLK1 iso4 (human) gap -
TLK1 (mouse) SSNHSFGSLGSLSDK S100
TLK1 (rat) SSNHSFGSLGSLSDK S100
S103-p
HsFGsLGsLsDKESE
0 4
TLK1 (human) HsFGsLGsLsDKESE S103-p
TLK1 iso2 (human) HSFGSLGSLSDKESE S103
TLK1 iso4 (human) gap -
TLK1 (mouse) HSFGSLGSLSDKESE S103
TLK1 (rat) HSFGSLGSLSDKESE S103
S105-p
FGsLGsLsDKESETP
0 6
TLK1 (human) FGsLGsLsDKESETP S105-p
TLK1 iso2 (human) FGSLGSLSDKESETP S105
TLK1 iso4 (human) gap -
TLK1 (mouse) FGSLGSLSDKESEtP S105
TLK1 (rat) FGSLGSLSDKESETP S105
T111
LsDKESETPEKKQSE
0 1
TLK1 (human) LsDKESETPEKKQSE T111
TLK1 iso2 (human) LSDKESETPEKKQSE T111
TLK1 iso4 (human) DLKTTGKTPEKKQSE T15
TLK1 (mouse) LSDKESEtPEKKQSE T111-p
TLK1 (rat) LSDKESETPEKKQSE T111
S133-p
KAENQNEssQGKsIG
0 6
TLK1 (human) KAENQNEssQGKsIG S133-p
TLK1 iso2 (human) KAENQNESSQGFPNL S133
TLK1 iso4 (human) KAENQNEssQGKsIG S37-p
TLK1 (mouse) KAESQNESSQGKSIG S133
TLK1 (rat) KAESQNESSQGKSIG S133
S134-p
AENQNEssQGKsIGG
0 8
TLK1 (human) AENQNEssQGKsIGG S134-p
TLK1 iso2 (human) AENQNESSQGFPNLP S134
TLK1 iso4 (human) AENQNEssQGKsIGG S38-p
TLK1 (mouse) AESQNESSQGKSIGG S134
TLK1 (rat) AESQNESSQGKSIGG S134
S138-p
NEssQGKsIGGRGHK
0 9
TLK1 (human) NEssQGKsIGGRGHK S138-p
TLK1 iso2 (human) GRTAGGKSIGGRGHK S159
TLK1 iso4 (human) NEssQGKsIGGRGHK S42-p
TLK1 (mouse) NESSQGKSIGGRGHK S138
TLK1 (rat) NESSQGKSIGGRGHK S138
S158-p
EYQGGNGssPVRGIP
0 4
TLK1 (human) EYQGGNGssPVRGIP S158-p
TLK1 iso2 (human) EYQGGNGSSPVRGIP S179
TLK1 iso4 (human) EYQGGNGSSPVRGIP S62
TLK1 (mouse) EYQGGNGssPVRGIP S158-p
TLK1 (rat) EYQGGNGSSPVRGIP S158
S159-p
YQGGNGssPVRGIPP
Upstream
0 32
Regulatory protein:
  • PRP4 (human)
Treatment
  • MG132_withdrawal
  • nocodazole
TLK1 (human) YQGGNGssPVRGIPP S159-p
TLK1 iso2 (human) YQGGNGSSPVRGIPP S180
TLK1 iso4 (human) YQGGNGSSPVRGIPP S63
TLK1 (mouse) YQGGNGssPVRGIPP S159-p
TLK1 (rat) YQGGNGSSPVRGIPP S159
S170-p
GIPPAIRsPQNSHsH
0 1
TLK1 (human) GIPPAIRsPQNSHsH S170-p
TLK1 iso2 (human) GIPPAIRSPQNSHSH S191
TLK1 iso4 (human) GIPPAIRSPQNSHSH S74
TLK1 (mouse) GIPPAIRSPQNSHSH S170
TLK1 (rat) GIPPAIRSPQNSHSH S170
S176-p
RsPQNSHsHSTPSSS
0 1
TLK1 (human) RsPQNSHsHSTPSSS S176-p
TLK1 iso2 (human) RSPQNSHSHSTPSSS S197
TLK1 iso4 (human) RSPQNSHSHSTPSSS S80
TLK1 (mouse) RSPQNSHSHStPsSS S176
TLK1 (rat) RSPQNSHSHSTPSSS S176
T179
QNSHsHSTPSSSVRP
0 1
TLK1 (human) QNSHsHSTPSSSVRP T179
TLK1 iso2 (human) QNSHSHSTPSSSVRP T200
TLK1 iso4 (human) QNSHSHSTPSSSVRP T83
TLK1 (mouse) QNSHSHStPsSSVRP T179-p
TLK1 (rat) QNSHSHSTPSSSVRP T179
S181
SHsHSTPSSSVRPNs
0 1
TLK1 (human) SHsHSTPSSSVRPNs S181
TLK1 iso2 (human) SHSHSTPSSSVRPNS S202
TLK1 iso4 (human) SHSHSTPSSSVRPNS S85
TLK1 (mouse) SHSHStPsSSVRPNS S181-p
TLK1 (rat) SHSHSTPSSSVRPNS S181
S188-p
SSSVRPNsPSPtALA
1 10
TLK1 (human) SSSVRPNsPSPtALA S188-p
TLK1 iso2 (human) SSSVRPNSPSPTALA S209
TLK1 iso4 (human) SSSVRPNSPSPTALA S92
TLK1 (mouse) sSSVRPNSPSPTALA S188
TLK1 (rat) SSSVRPNSPSPTALA S188
T192-p
RPNsPSPtALAFGDH
0 1
TLK1 (human) RPNsPSPtALAFGDH T192-p
TLK1 iso2 (human) RPNSPSPTALAFGDH T213
TLK1 iso4 (human) RPNSPSPTALAFGDH T96
TLK1 (mouse) RPNSPSPTALAFGDH T192
TLK1 (rat) RPNSPSPTALAFGDH T192
K234-ac
NKIQDLEkKEGRIDD
0 1
TLK1 (human) NKIQDLEkKEGRIDD K234-ac
TLK1 iso2 (human) NKIQDLEKKEGRIDD K255
TLK1 iso4 (human) NKIQDLEKKEGRIDD K138
TLK1 (mouse) TKNQDLEKKEGRIDD K234
TLK1 (rat) TKNQDLEKKEGRIDD K234
K269
KYKERLNKCISMSKK
0 1
TLK1 (human) KYKERLNKCISMSKK K269
TLK1 iso2 (human) KYKERLNKCISMSKK K290
TLK1 iso4 (human) KYKERLNKCISMSKK K173
TLK1 (mouse) KYKERLNkCISMSKK K269-ac
TLK1 (rat) KYKERLNKCISMSKK K269
T313-p
VRHGASFtEQWTDGF
0 1
TLK1 (human) VRHGASFtEQWTDGF T313-p
TLK1 iso2 (human) VRHGASFTEQWTDGF T334
TLK1 iso4 (human) VRHGASFTEQWTDGF T217
TLK1 (mouse) VRHGASFTEQWTDGF T313
TLK1 (rat) VRHGASFTEQWTDGF T313
S357-p
KPPTANNsQAPSTNS
0 2
TLK1 (human) KPPTANNsQAPSTNS S357-p
TLK1 iso2 (human) KPPTANNSQAPSTNS S378
TLK1 iso4 (human) KPPTANNSQAPSTNS S261
TLK1 (mouse) KPPTANNSQAPATNS S357
TLK1 (rat) KPPTANNSQAPATNS S357
S444-p
RINNEDNsQFKDHPT
0 1
TLK1 (human) RINNEDNsQFKDHPT S444-p
TLK1 iso2 (human) RINNEDNSQFKDHPT S465
TLK1 iso4 (human) RINNEDNSQFKDHPT S348
TLK1 (mouse) RINNEDNSQFKDHPT S444
TLK1 (rat) RINNEDNSQFKDHPT S444
K485-ub
EQRYAAVkIHQLNKS
0 1
TLK1 (human) EQRYAAVkIHQLNKS K485-ub
TLK1 iso2 (human) EQRYAAVKIHQLNKS K506
TLK1 iso4 (human) EQRYAAVKIHQLNKS K389
TLK1 (mouse) EQRYAAVKIHQLNKS K485
TLK1 (rat) EQRYAAVKIHQLNKS K485
S563-p
MSEKEARsIVMQIVN
0 1
TLK1 (human) MSEKEARsIVMQIVN S563-p
TLK1 iso2 (human) MSEKEARSIVMQIVN S584
TLK1 iso4 (human) MSEKEARSIVMQIVN S467
TLK1 (mouse) MSEKEARSIVMQIVN S563
TLK1 (rat) MSEKEARSIVMQIVN S563
K700-ub
TEVQFPVkPVVSSEA
0 4
TLK1 (human) TEVQFPVkPVVSSEA K700-ub
TLK1 iso2 (human) TEVQFPVKPVVSSEA K721
TLK1 iso4 (human) TEVQFPVKPVVSSEA K604
TLK1 (mouse) TEVQFPVkPVVSSEA K700-ub
TLK1 (rat) TEVQFPVKPVVSSEA K700
S741-p
LLPHMRRsNssGNLH
0 7
TLK1 (human) LLPHMRRsNssGNLH S741-p
TLK1 iso2 (human) LLPHMRRSNSSGNLH S762
TLK1 iso4 (human) LLPHMRRSNSSGNLH S645
TLK1 (mouse) LLPHMRRSNSSGNLH S741
TLK1 (rat) LLPHMRRSNSSGNLH S741
S743-p
PHMRRsNssGNLHMA
Upstream
Downstream
3 1
Effects on Modified Protein
  • enzymatic activity, inhibited
Kinase, in vitro:
  • Chk1 (human)
Putative in vivo kinases:
  • Chk1 (human)
Treatment
  • caffeine
  • ionizing_radiation
  • UCN-01
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TLK1 (human) PHMRRsNssGNLHMA S743-p
TLK1 iso2 (human) PHMRRSNSSGNLHMA S764
TLK1 iso4 (human) PHMRRSNSSGNLHMA S647
TLK1 (mouse) PHMRRSNSSGNLHMS S743
TLK1 (rat) PHMRRSNSSGNLHMS S743
S744-p
HMRRsNssGNLHMAG
0 1
TLK1 (human) HMRRsNssGNLHMAG S744-p
TLK1 iso2 (human) HMRRSNSSGNLHMAG S765
TLK1 iso4 (human) HMRRSNSSGNLHMAG S648
TLK1 (mouse) HMRRSNSSGNLHMSG S744
TLK1 (rat) HMRRSNSSGNLHMSG S744
S760-p
TASPTPPsSSIITY_
0 1
TLK1 (human) TASPTPPsSSIITY_ S760-p
TLK1 iso2 (human) TASPTPPSSSIITY_ S781
TLK1 iso4 (human) TASPTPPSSSIITY_ S664
TLK1 (mouse) TATPTPPSSSIITY_ S760
TLK1 (rat) TATPTPPSSSIITY_ S760