MAFA (human)

LTP

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

HTP

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

S13

AMGAELPSsPLAIEY

MAFA (human)	AMGAELPSsPLAIEY	S13
MAFA (mouse)	AMGAELPssPLAIEY	S13-p
MAFA (rat)	AMGAELPSSPLAIEY	S13
MAFA (quail)	AMTAELPTsPLAIEY	T13

S14-p

MGAELPSsPLAIEYV

Upstream

Downstream

Effects on Modified Protein

activity, induced

Effects on Biological Processes:

cell differentiation, altered
transcription, induced

Kinase, in vitro:

ERK2 (human)

Putative in vivo kinases:

ERK2 (human)
MEKK1 (human)

MAFA (human)	MGAELPSsPLAIEYV	S14-p
MAFA (mouse)	MGAELPssPLAIEYV	S14-p
MAFA (rat)	MGAELPSSPLAIEYV	S14
MAFA (quail)	MTAELPTsPLAIEYV	S14-p

K32-sm

DLMKFEVkKEPPEAE

Upstream

Downstream

Effects on Biological Processes:

transcription, inhibited

Treatment

anisomycin
catalase
ethanol
H2O2
heat_shock
ionomycin
KCl
low_glucose
medium change
NAC
TNF

MAFA (human)	DLMKFEVkKEPPEAE	K32-sm
MAFA (mouse)	DLMKFEVkKEPPEAE	K32-sm
MAFA (rat)	DLMKFEVKKEPPEAE	K32
MAFA (quail)	DLMKFEVKKEPAEAE	K32

S49-p

CHRLPPGsLSStPLS

Upstream

Downstream

Effects on Modified Protein

molecular association, regulation
protein degradation
ubiquitination

Effects on Biological Processes:

carcinogenesis, induced
transcription, induced

Kinase, in vitro:

GSK3B (human)

Putative in vivo kinases:

GSK3A (human)
GSK3B (human)

MAFA (human)	CHRLPPGsLSStPLS	S49-p
MAFA (mouse)	CHRLPPGsLSStPLS	S49-p
MAFA (rat)	CHRLPPGSLSSTPLS	S49
MAFA (quail)	CHRLPAGSLSSTPLS	S49

T53-p

PPGsLSStPLStPCS

Upstream

Downstream

Effects on Modified Protein

molecular association, regulation
protein degradation
ubiquitination

Effects on Biological Processes:

carcinogenesis, induced
transcription, induced

Kinase, in vitro:

GSK3B (human)

Putative in vivo kinases:

GSK3A (human)
GSK3B (human)

Treatment

1-azakenpaullone
lithium
seliciclib
U0126

MAFA (human)	PPGsLSStPLStPCS	T53-p
MAFA (mouse)	PPGsLSStPLStPCS	T53-p
MAFA (rat)	PPGSLSSTPLSTPCS	T53
MAFA (quail)	PAGSLSSTPLStPCS	T53

T57-p

LSStPLStPCSsVPS

Upstream

Downstream

Effects on Modified Protein

activity, induced
molecular association, regulation
protein degradation
ubiquitination

Effects on Biological Processes:

carcinogenesis, induced
signaling pathway regulation
transcription, induced

Kinase, in vitro:

GSK3B (human)

Putative in vivo kinases:

GSK3A (human)
GSK3B (human)
P38A (human)

Treatment

1-azakenpaullone
lithium
SB203580
seliciclib
U0126

MAFA (human)	LSStPLStPCSsVPS	T57-p
MAFA (mouse)	LSStPLStPCSsVPS	T57-p
MAFA (rat)	LSSTPLSTPCSSVPS	T57
MAFA (quail)	LSSTPLStPCSSVPS	T57-p

S61-p

PLStPCSsVPSsPSF

Upstream

Downstream

Effects on Modified Protein

molecular association, regulation
protein degradation
ubiquitination

Effects on Biological Processes:

carcinogenesis, induced
transcription, induced

Kinase, in vitro:

GSK3B (human)

Putative in vivo kinases:

GSK3A (human)
GSK3B (human)

MAFA (human)	PLStPCSsVPSsPSF	S61-p
MAFA (mouse)	PLStPCSsVPSsPSF	S61-p
MAFA (rat)	PLSTPCSSVPSSPSF	S61
MAFA (quail)	PLStPCSSVPSSPSF	S61

S65-p

PCSsVPSsPSFCAPS

Upstream

Downstream

Effects on Modified Protein

activity, induced
protein degradation

Effects on Biological Processes:

cell differentiation, altered
transcription, induced

Kinase, in vitro:

ERK2 (human)

Putative in vivo kinases:

ERK2 (human)
MEKK1 (human)

MAFA (human)	PCSsVPSsPSFCAPS	S65-p
MAFA (mouse)	PCSsVPSsPSFCAPS	S65-p
MAFA (rat)	PCSSVPSSPSFCAPS	S65
MAFA (quail)	PCSSVPSSPSFCAPS	S65

S98

GGAPGPPSGGPGAVG

MAFA (human)	GGAPGPPSGGPGAVG	S98
MAFA (mouse)	GGAPGPPsGGPGTVG	S96-p
MAFA (rat)	GGAPGPPSGGPGTVG	S96
MAFA (quail)	PSPGGQPSAGPTAAP	S78

S120

LEDLYWMSGYQHHLN

MAFA (human)	LEDLYWMSGYQHHLN	S120
MAFA (mouse)	LEDLYWMsGYQHHLN	S118-p
MAFA (rat)	LEDLYWMSGYQHHLN	S118
MAFA (quail)	LEELYWMSGYQHHLN	S99

T134-p

NPEALNLtPEDAVEA

Upstream

Downstream

Effects on Modified Protein

protein degradation

Effects on Biological Processes:

signaling pathway regulation

Putative in vivo kinases:

P38A (human)

Treatment

SB203580

MAFA (human)	NPEALNLtPEDAVEA	T134-p
MAFA (mouse)	NPEALNLtPEDAVEA	T132-p
MAFA (rat)	NPEALNLTPEDAVEA	T132
MAFA (quail)	NPEALNLtPEDAVEA	T113-p

S145

AVEALIGSGHHGAHH

MAFA (human)	AVEALIGSGHHGAHH	S145
MAFA (mouse)	AVEALIGsGHHGAHH	S143-p
MAFA (rat)	AVEALIGSGHHSAHH	S143
MAFA (quail)	AVEALIGAPHHHHHH	A124

Y163

HPAAAAAYEAFRGPG

MAFA (human)	HPAAAAAYEAFRGPG	Y163
MAFA (mouse)	HPAAAAAyEAFRGQs	Y161-p
MAFA (rat)	HPAAAAAYEAFRGQS	Y161
MAFA (quail)	HHHHHQSYESFRPQP	Y135

G170

YEAFRGPGFAGGGGA

MAFA (human)	YEAFRGPGFAGGGGA	G170
MAFA (mouse)	yEAFRGQsFAGGGGA	S168-p
MAFA (rat)	YEAFRGQSFAGGGGG	S168
MAFA (quail)	YESFRPQPFGGEELP	P142

S228

VRLEERFSDDQLVSM

MAFA (human)	VRLEERFSDDQLVSM	S228
MAFA (mouse)	VRLEERFsDDQLVsM	S234-p
MAFA (rat)	VRLEERFSDDQLVSM	S236
MAFA (quail)	LRLEERFSDDQLVSM	S173

S234

FSDDQLVSMSVRELN

MAFA (human)	FSDDQLVSMSVRELN	S234
MAFA (mouse)	FsDDQLVsMsVRELN	S240-p
MAFA (rat)	FSDDQLVSMSVRELN	S242
MAFA (quail)	FSDDQLVSMSVRELN	S179

S236

DDQLVSMSVRELNRQ

MAFA (human)	DDQLVSMSVRELNRQ	S236
MAFA (mouse)	DDQLVsMsVRELNRQ	S242-p
MAFA (rat)	DDQLVSMSVRELNRQ	S244
MAFA (quail)	DDQLVSMSVRELNRQ	S181

S248

NRQLRGFSKEEVIRL

MAFA (human)	NRQLRGFSKEEVIRL	S248
MAFA (mouse)	NRQLRGFsKEEVIRL	S254-p
MAFA (rat)	NRQLRGFSKEEVIRL	S256
MAFA (quail)	NRQLRGFSKEEVIRL	S193

S270

KNRGYAQSCRFKRVQ

MAFA (human)	KNRGYAQSCRFKRVQ	S270
MAFA (mouse)	KNRGYAQsCRFKRVQ	S276-p
MAFA (rat)	KNRGYAQSCRFKRVQ	S278
MAFA (quail)	KNRGYAQSCRYKRVQ	S215

S284

QQRHILESEKCQLQS

MAFA (human)	QQRHILESEKCQLQS	S284
MAFA (mouse)	QQRHILEsEKCQLQs	S290-p
MAFA (rat)	QQRHILESEKCQLQS	S292
MAFA (quail)	QQRHILENEKCQLQS	N229

S291

SEKCQLQSQVEQLKL

MAFA (human)	SEKCQLQSQVEQLKL	S291
MAFA (mouse)	sEKCQLQsQVEQLKL	S297-p
MAFA (rat)	SEKCQLQSQVEQLKL	S299
MAFA (quail)	NEKCQLQSQVEQLKQ	S236

Y310

LAKERDLYKEKyEKL

MAFA (human)	LAKERDLYKEKyEKL	Y310
MAFA (mouse)	LAKERDLyKEKyEKL	Y316-p
MAFA (rat)	LAKERDLYKEKYEKL	Y318
MAFA (quail)	LAKERDLYKEKYEKL	Y255

Y314-p

RDLYKEKyEKLAGRG

MAFA (human)	RDLYKEKyEKLAGRG	Y314-p
MAFA (mouse)	RDLyKEKyEKLAGRG	Y320-p
MAFA (rat)	RDLYKEKYEKLAGRG	Y322
MAFA (quail)	RDLYKEKYEKLAARG	Y259

S336-p

AGFPREPsPPQAGPG

MAFA (human)	AGFPREPsPPQAGPG	S336-p
MAFA (mouse)	AGFPREPsPAQAGPG	S342-p
MAFA (rat)	AGFPREPSPAQAGPG	S344
MAFA (quail)	RGFPRETsPPAAPKT	S272-p