Other Species / Isoforms
  IRF5 (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

 HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
T10-p
QSIPVAPtPPRRVRL
1 2
IRF5 (human) QSIPVAPtPPRRVRL T10-p
IRF5 iso2 (human) QSIPVAPTPPRRVRL T10
IRF5 (mouse) HSAPGIPPPPRRVRL P10
IRF5 (rat) QSAPGIPTPPRRVRL T10
Y136-p
DSQPPEDySFGAGEE
0 1
IRF5 (human) DSQPPEDySFGAGEE Y136-p
IRF5 iso2 (human) DSQPPEDYSFGAGEE Y136
IRF5 (mouse) ESQPTDDYVLGEEEE Y136
IRF5 (rat) ESQPTDDYVLGEEEE Y136
S158-p
QRMLPSLsLTEDVKW
Upstream
Downstream
1 1
Effects on Modified Protein
  • intracellular localization
Effects on Biological Processes:
  • apoptosis, induced
Kinase, in vitro:
  • TBK1 (human)
Putative in vivo kinases:
  • TBK1 (human)
IRF5 (human) QRMLPSLsLTEDVKW S158-p
IRF5 iso2 (human) QRMLPSLSLTDAVQS S158
IRF5 (mouse) QRMLPGLSITEPALP S157
IRF5 (rat) QRMLPGLSITEPVLP S157
S293-p
VELFGPIsLEQVRFP
Upstream
1 1
Kinase, in vitro:
  • TBK1 (human)
Putative in vivo kinases:
  • TBK1 (human)
IRF5 (human) VELFGPIsLEQVRFP S293-p
IRF5 iso2 (human) VELFGPISLEQVRFP S309
IRF5 (mouse) VELFGPVTLEQVRFP T292
IRF5 (rat) VELFGPVTLEQVRFP T292
S301-p
LEQVRFPsPEDIPSD
1 1
IRF5 (human) LEQVRFPsPEDIPSD S301-p
IRF5 iso2 (human) LEQVRFPSPEDIPSD S317
IRF5 (mouse) LEQVRFPSPEDIPSD S300
IRF5 (rat) LEQVRFPSPEDIPSD S300
K309-ub
PEDIPSDkQRFyTNQ
0 3
IRF5 (human) PEDIPSDkQRFyTNQ K309-ub
IRF5 iso2 (human) PEDIPSDKQRFYTNQ K325
IRF5 (mouse) PEDIPSDKQRFYTNQ K308
IRF5 (rat) PEDIPSDKQRFYTNQ K308
Y313-p
PSDkQRFyTNQLLDV
Upstream
Downstream
1 1
Effects on Modified Protein
  • molecular association, regulation
  • ubiquitination
Effects on Biological Processes:
  • transcription, inhibited
Putative in vivo kinases:
  • LYN (human)
IRF5 (human) PSDkQRFyTNQLLDV Y313-p
IRF5 iso2 (human) PSDKQRFYTNQLLDV Y329
IRF5 (mouse) PSDKQRFYTNQLLDV Y312
IRF5 (rat) PSDKQRFYTNQLLDV Y312
Y335-p
QLQGQDLyAIRLCQC
Upstream
Downstream
1 3
Effects on Modified Protein
  • molecular association, regulation
  • ubiquitination
Effects on Biological Processes:
  • transcription, inhibited
Putative in vivo kinases:
  • LYN (human)
IRF5 (human) QLQGQDLyAIRLCQC Y335-p
IRF5 iso2 (human) QLQGQDLYAIRLCQC Y351
IRF5 (mouse) QLQGQDLyAIRLCQC Y334-p
IRF5 (rat) QLQGQDLYAIRLCQC Y334
K411-ub
PDRKPREkkLITVQV
Downstream
2 1
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
  • ubiquitination
Effects on Biological Processes:
  • transcription, induced
  • transcription, inhibited
IRF5 (human) PDRKPREkkLITVQV K411-ub
IRF5 iso2 (human) PDRKPREKKLITVQV K427
IRF5 (mouse) PDVKPREKKLITVQV K410
IRF5 (rat) PDLKPREKKLITVQV K410
K412-ub
DRKPREkkLITVQVV
Downstream
2 1
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
  • ubiquitination
Effects on Biological Processes:
  • transcription, induced
  • transcription, inhibited
IRF5 (human) DRKPREkkLITVQVV K412-ub
IRF5 iso2 (human) DRKPREKKLITVQVV K428
IRF5 (mouse) DVKPREKKLITVQVV K411
IRF5 (rat) DLKPREKKLITVQVV K411
S435-p
EMFSGELsWsADsIR
Downstream
3 1
Effects on Modified Protein
  • activity, induced
  • intracellular localization
Effects on Biological Processes:
  • apoptosis, induced
  • transcription, induced
IRF5 (human) EMFSGELsWsADsIR S435-p
IRF5 iso2 (human) EMFSGELSWSADSIR S451
IRF5 (mouse) EMFSGELSWSADSIR S434
IRF5 (rat) EMFSGELSWSADSIR S434
S437-p
FSGELsWsADsIRLQ
Downstream
2 0
Effects on Modified Protein
  • activity, induced
Effects on Biological Processes:
  • transcription, induced
IRF5 (human) FSGELsWsADsIRLQ S437-p
IRF5 iso2 (human) FSGELSWSADSIRLQ S453
IRF5 (mouse) FSGELSWSADSIRLQ S436
IRF5 (rat) FSGELSWSADSIRLQ S436
S440-p
ELsWsADsIRLQIsN
Downstream
2 0
Effects on Modified Protein
  • activity, induced
  • molecular association, regulation
Effects on Biological Processes:
  • transcription, induced
IRF5 (human) ELsWsADsIRLQIsN S440-p
IRF5 iso2 (human) ELSWSADSIRLQISN S456
IRF5 (mouse) ELSWSADSIRLQISN S439
IRF5 (rat) ELSWSADSIRLQISN S439
S446-p
DsIRLQIsNPDLKDR
Upstream
Downstream
3 2
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
  • protein stabilization
Effects on Biological Processes:
  • apoptosis, induced
  • transcription, induced
Kinase, in vitro:
  • IKKB (human)
Putative in vivo kinases:
  • IKKB (human)
Treatment
  • CL097
IRF5 (human) DsIRLQIsNPDLKDR S446-p
IRF5 iso2 (human) DSIRLQISNPDLKDR S462
IRF5 (mouse) DSIRLQISNPDLKDH S445
IRF5 (rat) DSIRLQISNPDLKDH S445