Other Species / Isoforms
  TRPC6 (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

 HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
S4-p
____MSQsPAFGPRr
1 2
TRPC6 (human) ____MSQsPAFGPRr S4-p
TRPC6 iso2 (human) ____MSQSPAFGPRR S4
TRPC6 (mouse) ____MSQSPRFVTRR S4
TRPC6 (rat) ____MSQsPGFVTRR S4-p
TRPC6 iso2 (rat) gap -
R11-m1
sPAFGPRrGssPrGA
0 1
TRPC6 (human) sPAFGPRrGssPrGA R11-m1
TRPC6 iso2 (human) SPAFGPRRGSSPRGA R11
TRPC6 (mouse) SPRFVTRRGGsLKAA R11
TRPC6 (rat) sPGFVTRRGGSPKAA R11
TRPC6 iso2 (rat) gap -
S13-p
AFGPRrGssPrGAAG
Upstream
1 4
Treatment
  • gefitinib
TRPC6 (human) AFGPRrGssPrGAAG S13-p
TRPC6 iso2 (human) AFGPRRGSSPRGAAG S13
TRPC6 (mouse) RFVTRRGGsLKAAPG G13
TRPC6 (rat) GFVTRRGGSPKAAPG G13
TRPC6 iso2 (rat) gap -
S14-p
FGPRrGssPrGAAGA
Upstream
Downstream
2 4
Effects on Modified Protein
  • intracellular localization
Kinase, in vitro:
  • CDK5 (human)
Putative in vivo kinases:
  • CDK5 (human)
Treatment
  • gefitinib
TRPC6 (human) FGPRrGssPrGAAGA S14-p
TRPC6 iso2 (human) FGPRRGSSPRGAAGA S14
TRPC6 (mouse) FVTRRGGsLKAAPGA S14-p
TRPC6 (rat) FVTRRGGSPKAAPGA S14
TRPC6 iso2 (rat) gap -
R16-m1
PRrGssPrGAAGAAA
0 1
TRPC6 (human) PRrGssPrGAAGAAA R16-m1
TRPC6 iso2 (human) PRRGSSPRGAAGAAA R16
TRPC6 (mouse) TRRGGsLKAAPGAGT K16
TRPC6 (rat) TRRGGSPKAAPGAGA K16
TRPC6 iso2 (rat) gap -
S28
AAARRNESQDyLLMD
1 0
TRPC6 (human) AAARRNESQDyLLMD S28
TRPC6 iso2 (human) AAARRNESQDYLLMD S28
TRPC6 (mouse) AGTRRNEsQDYLLMD S28-p
TRPC6 (rat) AGARRNESQDYLLMD S28
TRPC6 iso2 (rat) gap -
Y31-p
RRNESQDyLLMDSEL
1 2
TRPC6 (human) RRNESQDyLLMDSEL Y31-p
TRPC6 iso2 (human) RRNESQDYLLMDSEL Y31
TRPC6 (mouse) RRNEsQDYLLMDELG Y31
TRPC6 (rat) RRNESQDYLLMDELG Y31
TRPC6 iso2 (rat) gap -
T70-p
RLAHRRQtVLREKGR
Upstream
Downstream
10 8
Effects on Modified Protein
  • activity, inhibited
Effects on Biological Processes:
  • cell motility, inhibited
Kinase, in vitro:
  • PKACA (human)
  • PKG1 (human)
Putative in vivo kinases:
  • PKACA (human)
  • PKG1 (human)
Regulatory protein:
  • PKACA (human)
Treatment
  • ANP
  • cGMP_analog
  • H-89
  • NKH_477
  • Rp-8pCPT-cGMPS
TRPC6 (human) RLAHRRQtVLREKGR T70-p
TRPC6 iso2 (human) RLAHRRQTVLREKGR T70
TRPC6 (mouse) RLTHRRQtILREKGR T69-p
TRPC6 (rat) RLTHRRQtVLREKGR T69-p
TRPC6 iso2 (rat) RLTHRRQTVLREKGR T15
K171
ALLLAISKGYVRIVE
0 1
TRPC6 (human) ALLLAISKGYVRIVE K171
TRPC6 iso2 (human) ALLLAISKGYVRIVE K171
TRPC6 (mouse) ALLLAISKGYVRIVE K170
TRPC6 (rat) ALLLAISkGYVRIVE K170-ac
TRPC6 iso2 (rat) ALLLAISKGYVRIVE K116
S282-p
NAYKGLAsPAYLSLS
Downstream
2 0
Effects on Modified Protein
  • phosphorylation
Effects on Biological Processes:
  • signaling pathway regulation
TRPC6 (human) NAYKGLAsPAYLSLS S282-p
TRPC6 iso2 (human) NAYKGLASPAYLSLS S282
TRPC6 (mouse) NAYKGLAsPAYLSLS S281-p
TRPC6 (rat) NAYKGLASPAYLSLS S281
TRPC6 iso2 (rat) NAYKGLASPAYLSLS S227
S322-p
KNDYKKLsMQCKDFV
Upstream
Downstream
5 0
Effects on Modified Protein
  • activity, inhibited
Kinase, in vitro:
  • PKG1 (human)
TRPC6 (human) KNDYKKLsMQCKDFV S322-p
TRPC6 iso2 (human) gap -
TRPC6 (mouse) KNDYRKLsMQCKDFV S321-p
TRPC6 (rat) KNDYRKLSMQCKDFV S321
TRPC6 iso2 (rat) KNDYRKLSMQCKDFV S267
S449
KFVAHAASFTIFLGL
1 0
TRPC6 (human) KFVAHAASFTIFLGL S449
TRPC6 iso2 (human) KFVAHAASFTIFLGL S333
TRPC6 (mouse) KFVAHAAsFTIFLGL S448-p
TRPC6 (rat) KFVAHAASFTIFLGL S448
TRPC6 iso2 (rat) KFVAHAASFTIFLGL S394
N473
EGTKLLPNETSTDNA
0 1
TRPC6 (human) EGTKLLPNETSTDNA N473
TRPC6 iso2 (human) EGTKLLPNETSTDNA N357
TRPC6 (mouse) EGTKLLPnETSTDNA N472-ng
TRPC6 (rat) EGTKLLPNETSTDNA N472
TRPC6 iso2 (rat) EGTKLLPNETSTDNA N418
T488
KQLFRMKTSCFSWME
1 0
TRPC6 (human) KQLFRMKTSCFSWME T488
TRPC6 iso2 (human) KQLFRMKTSCFSWME T372
TRPC6 (mouse) RQLFRMKtSCFSWME T487-p
TRPC6 (rat) RQLFRMKTSCFSWME T487
TRPC6 iso2 (rat) RQLFRMKTSCFSWME T433
N561
AQSIIDANDTLKDLT
0 1
TRPC6 (human) AQSIIDANDTLKDLT N561
TRPC6 iso2 (human) AQSIIDANDTLKDLT N445
TRPC6 (mouse) AQSIIDAnDTLKDLT N560-ng
TRPC6 (rat) AQSIIDANDTLKDLT N560
TRPC6 iso2 (rat) AQSIIDANDTLKDLT N506
T759-p
SYFEEGRtLPVPFNL
0 1
TRPC6 (human) SYFEEGRtLPVPFNL T759-p
TRPC6 iso2 (human) SYFEEGRTLPVPFNL T643
TRPC6 (mouse) SYFEEGRTLPVPFNL T758
TRPC6 (rat) SYFEEGRTLPVPFNL T758
TRPC6 iso2 (rat) SYFEEGRTLPVPFNL T704
S769
VPFNLVPSPKSLFyL
1 0
TRPC6 (human) VPFNLVPSPKSLFyL S769
TRPC6 iso2 (human) VPFNLVPSPKSLFYL S653
TRPC6 (mouse) VPFNLVPSPKSLLYL S768
TRPC6 (rat) VPFNLVPsPKSLLYL S768-p
TRPC6 iso2 (rat) VPFNLVPsPKSLLYL S714-p
Y775-p
PSPKSLFyLLLKLKK
0 1
TRPC6 (human) PSPKSLFyLLLKLKK Y775-p
TRPC6 iso2 (human) PSPKSLFYLLLKLKK Y659
TRPC6 (mouse) PSPKSLLYLLLKFKK Y774
TRPC6 (rat) PsPKSLLYLLLKFKK Y774
TRPC6 iso2 (rat) PsPKSLLYLLLKFKK Y720
S785-p
LKLKKWIsELFQGHK
0 1
TRPC6 (human) LKLKKWIsELFQGHK S785-p
TRPC6 iso2 (human) LKLKKWISELFQGHK S669
TRPC6 (mouse) LKFKKWMCELIQGQK C784
TRPC6 (rat) LKFKKWMSELIQGHK S784
TRPC6 iso2 (rat) LKFKKWMSELIQGHK S730
L813
EEKKLGILGsHEDLS
0 1
TRPC6 (human) EEKKLGILGsHEDLS L813
TRPC6 iso2 (human) EEKKLGILGSHEDLS L697
TRPC6 (mouse) EEKKFGIsGsHEDLS S812-p
TRPC6 (rat) EEKKFGILGsHEDLS L812
TRPC6 iso2 (rat) EEKKFGILGSHEDLS L758
S815-p
KKLGILGsHEDLSKL
2 12
TRPC6 (human) KKLGILGsHEDLSKL S815-p
TRPC6 iso2 (human) KKLGILGSHEDLSKL S699
TRPC6 (mouse) KKFGIsGsHEDLSKF S814-p
TRPC6 (rat) KKFGILGsHEDLSKF S814-p
TRPC6 iso2 (rat) KKFGILGSHEDLSKF S760
P835
QVGHNKQPsIRsSED
0 1
TRPC6 (human) QVGHNKQPsIRsSED P835
TRPC6 iso2 (human) QVGHNKQPSIRSSED P719
TRPC6 (mouse) QLAHNKQssTRSSED S834-p
TRPC6 (rat) QLAHNKQSSTRSSED S834
TRPC6 iso2 (rat) QLAHNKQSSTRSSED S780
S836-p
VGHNKQPsIRsSEDF
0 2
TRPC6 (human) VGHNKQPsIRsSEDF S836-p
TRPC6 iso2 (human) VGHNKQPSIRSSEDF S720
TRPC6 (mouse) LAHNKQssTRSSEDY S835-p
TRPC6 (rat) LAHNKQSSTRSSEDF S835
TRPC6 iso2 (rat) LAHNKQSSTRSSEDF S781
S839-p
NKQPsIRsSEDFHLN
0 1
TRPC6 (human) NKQPsIRsSEDFHLN S839-p
TRPC6 iso2 (human) NKQPSIRSSEDFHLN S723
TRPC6 (mouse) NKQssTRSSEDYHLN S838
TRPC6 (rat) NKQSSTRSSEDFHLN S838
TRPC6 iso2 (rat) NKQSSTRSSEDFHLN S784