Other Species / Isoforms
  RIPK3 (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

  HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
S2
______MSCVkLWPS
1 1
RIPK3 (human) ______MSCVkLWPS S2
RIPK3 (mouse) ______MsSVkLWPT S2-p
RIPK3 (rat) ______MSSVKLWLN S2
K5-ub
___MSCVkLWPSGAP
1 2
RIPK3 (human) ___MSCVkLWPSGAP K5-ub
RIPK3 (mouse) ___MsSVkLWPTGAS K5-ub
RIPK3 (rat) ___MSSVKLWLNGAS K5
K42-ub
VFRAQHRkWGYDVAV
1 1
RIPK3 (human) VFRAQHRkWGYDVAV K42-ub
RIPK3 (mouse) VFRAHHRTWNHDVAV T43
RIPK3 (rat) VFRARHTAWNLDVAV A43
K55-ub
AVKIVNSkAISREVK
0 1
RIPK3 (human) AVKIVNSkAISREVK K55-ub
RIPK3 (mouse) AVKIVNSKKISWEVK K56
RIPK3 (rat) AVKIVNSKKISREVK K56
S164-p
KLADFGLstFQGGSQ
Downstream
3 2
Effects on Modified Protein
  • enzymatic activity, inhibited
  • phosphorylation
RIPK3 (human) KLADFGLstFQGGSQ S164-p
RIPK3 (mouse) KLADFGLsTFQGGSQ S165-p
RIPK3 (rat) KLADFGLSTFQGGSQ S165
T165-p
LADFGLstFQGGSQS
Downstream
1 0
Effects on Modified Protein
  • enzymatic activity, inhibited
  • phosphorylation
RIPK3 (human) LADFGLstFQGGSQS T165-p
RIPK3 (mouse) LADFGLsTFQGGSQS T166
RIPK3 (rat) LADFGLSTFQGGSQS T166
P179
SGTGSGEPGGtLGYL
0 3
RIPK3 (human) SGTGSGEPGGtLGYL P179
RIPK3 (mouse) SGSGSRDsGGTLAYL S184-p
RIPK3 (rat) SGSGSRDSGGTLAYL S182
T182-p
GSGEPGGtLGYLAPE
Upstream
Downstream
1 1
Effects on Modified Protein
  • enzymatic activity, induced
  • molecular association, regulation
Effects on Biological Processes:
  • apoptosis, induced
Kinase, in vitro:
  • RIPK3 (human)
Treatment
  • dabrafenib
  • LCL161
  • TNF
  • Z-VAD-FMK
view more >
RIPK3 (human) GSGEPGGtLGYLAPE T182-p
RIPK3 (mouse) GSRDsGGTLAYLDPE T187
RIPK3 (rat) GSRDSGGTLAYLAPE T185
T224-p
GREVELPtEPsLVYE
Upstream
Downstream
1 3
Effects on Modified Protein
  • molecular association, regulation
Putative in vivo kinases:
  • RIPK3 (human)
Treatment
  • compound A
  • IDN-6556
  • ischemia
  • TNF
view more >
RIPK3 (human) GREVELPtEPsLVYE T224-p
RIPK3 (mouse) GREAELVDKtsLIRE D229
RIPK3 (rat) GREAEVVDKTSLIRG D226
P226
EVELPtEPsLVYEAV
12 2
RIPK3 (mouse)
T231-p
RIPK3 (human) EVELPtEPsLVYEAV P226
RIPK3 (mouse) EAELVDKtsLIRETV T231-p
RIPK3 (rat) EAEVVDKTSLIRGAV T228
S227-p
VELPtEPsLVYEAVC
Upstream
Downstream
22 7
RIPK3 (human)
S227-p
RIPK3 (mouse)
S232-p
Effects on Modified Protein
  • molecular association, regulation
  • phosphorylation
Effects on Biological Processes:
  • signaling pathway regulation
Kinase, in vitro:
  • RIPK3 (human)
Putative in vivo kinases:
  • RIPK3 (human)
Regulatory protein:
  • MLKL (human)
  • RIPK1 (human)
Treatment
  • compound A
  • IDN-6556
  • ischemia
  • Necrostatin-1
  • phenhydan
  • smac
  • TNF
  • Z-VAD-FMK
view more >
RIPK3 (human) VELPtEPsLVYEAVC S227-p
RIPK3 (mouse) AELVDKtsLIRETVC S232-p
RIPK3 (rat) AEVVDKTSLIRGAVC S229
S241-p
CNRQNRPsLAELPQA
0 1
RIPK3 (human) CNRQNRPsLAELPQA S241-p
RIPK3 (mouse) CDRQSRPPLTELPPG P246
RIPK3 (rat) CNRQRRPPLTELPPD P243
T252-p
LPQAGPEtPGLEGLK
1 2
RIPK3 (human) LPQAGPEtPGLEGLK T252-p
RIPK3 (mouse) LPPGSPEtPGLEKLk T257-p
RIPK3 (rat) LPPDSPETPGLEGLK T254
K259
tPGLEGLKELMQLCW
1 0
RIPK3 (human) tPGLEGLKELMQLCW K259
RIPK3 (mouse) tPGLEKLkELMIHCW K264-ub
RIPK3 (rat) TPGLEGLKELMTHCW K261
S299-p
NNMNAAVstVKDFLS
1 2
RIPK3 (human) NNMNAAVstVKDFLS S299-p
RIPK3 (mouse) DKVDAAVsEVKHYLS S304-p
RIPK3 (rat) DKVDAAVSKVKHYLS S301
T300-p
NMNAAVstVKDFLSQ
0 1
RIPK3 (human) NMNAAVstVKDFLSQ T300-p
RIPK3 (mouse) KVDAAVsEVKHYLSQ E305
RIPK3 (rat) KVDAAVSKVKHYLSQ K302
S316-p
RSSNRRFsIPEsGQG
0 21
RIPK3 (human) RSSNRRFsIPEsGQG S316-p
RIPK3 (mouse) RSSGRNLSAREPsQR S321
RIPK3 (rat) RSSDTKLSARESSQK S318
S320-p
RRFsIPEsGQGGtEM
0 2
RIPK3 (human) RRFsIPEsGQGGtEM S320-p
RIPK3 (mouse) RNLSAREPsQRGTEM P325
RIPK3 (rat) TKLSARESSQKGTEV S322
G321
RFsIPEsGQGGtEMD
1 3
RIPK3 (human) RFsIPEsGQGGtEMD G321
RIPK3 (mouse) NLSAREPsQRGTEMD S326-p
RIPK3 (rat) KLSARESSQKGTEVD S323
T325-p
PEsGQGGtEMDGFRR
0 2
RIPK3 (human) PEsGQGGtEMDGFRR T325-p
RIPK3 (mouse) REPsQRGTEMDCPRE T330
RIPK3 (rat) RESSQKGTEVDCPRE T327
T333
EMDGFRRTIENQHsR
1 1
RIPK3 (human) EMDGFRRTIENQHsR T333
RIPK3 (mouse) EMDCPREtMVSKMLD T338-p
RIPK3 (rat) EVDCPRETIVYEMLD T335
S339-p
RTIENQHsRNDVMVS
0 5
RIPK3 (human) RTIENQHsRNDVMVS S339-p
RIPK3 (mouse) gap -
RIPK3 (rat) gap -
K351-ub
MVSEWLNkLNLEEPP
1 0
RIPK3 (human) MVSEWLNkLNLEEPP K351-ub
RIPK3 (mouse) MVSKMLDRLHLEEPs R346
RIPK3 (rat) IVYEMLDRLHLEEPS R343
P358
kLNLEEPPsSVPKKC
1 1
RIPK3 (human) kLNLEEPPsSVPKKC P358
RIPK3 (mouse) RLHLEEPsGPVPGKC S353-p
RIPK3 (rat) RLHLEEPSGSVPERL S350
S359-p
LNLEEPPsSVPKKCP
0 1
RIPK3 (human) LNLEEPPsSVPKKCP S359-p
RIPK3 (mouse) LHLEEPsGPVPGKCP G354
RIPK3 (rat) LHLEEPSGSVPERLT G351
S372-p
CPSLTKRsRAQEEQV
0 1
RIPK3 (human) CPSLTKRsRAQEEQV S372-p
RIPK3 (mouse) VPGKCPERQAQDTsV R363
RIPK3 (rat) RLTSLTERRGKEASF R363
Q378
RsRAQEEQVPQAWTA
2 2
RIPK3 (human) RsRAQEEQVPQAWTA Q378
RIPK3 (mouse) ERQAQDTsVGPAtPA S369-p
RIPK3 (rat) ERRGKEASFGHATPA S369
W383
EEQVPQAWTAGTSSD
0 2
RIPK3 (human) EEQVPQAWTAGTSSD W383
RIPK3 (mouse) DTsVGPAtPARTSsD T374-p
RIPK3 (rat) EASFGHATPAGTSSD T374
S389
AWTAGTSSDSMAQPP
1 2
RIPK3 (human) AWTAGTSSDSMAQPP S389
RIPK3 (mouse) AtPARTSsDPVAGTP S380-p
RIPK3 (rat) ATPAGTSSDTLAGTP S380
T401
QPPQTPETSTFRNQM
1 1
RIPK3 (human) QPPQTPETSTFRNQM T401
RIPK3 (mouse) GTPQIPHtLPFRGTt T392-p
RIPK3 (rat) GTPQIPHTLPSRGTT T392
M408
TSTFRNQMPsPtSTG
0 1
RIPK3 (human) TSTFRNQMPsPtSTG M408
RIPK3 (mouse) tLPFRGTtPGPVFTE T399-p
RIPK3 (rat) TLPSRGTTPRPAFTE T399
S410-p
TFRNQMPsPtSTGTP
0 6
RIPK3 (human) TFRNQMPsPtSTGTP S410-p
RIPK3 (mouse) PFRGTtPGPVFTETP G401
RIPK3 (rat) PSRGTTPRPAFTETP R401
T412-p
RNQMPsPtSTGTPSP
0 1
RIPK3 (human) RNQMPsPtSTGTPSP T412-p
RIPK3 (mouse) RGTtPGPVFTETPGP V403
RIPK3 (rat) RGTTPRPAFTETPGP A403
R486-m1
LAPSGKGrGLQHPPP
0 1
RIPK3 (human) LAPSGKGrGLQHPPP R486-m1
RIPK3 (mouse) gap -
RIPK3 (rat) gap -
R508
KDPEAWSRPQGWYNH
0 17
RIPK3 (human) KDPEAWSRPQGWYNH R508
RIPK3 (mouse) YDQAQFGrGrGWQPF R477-m1
RIPK3 (rat) KEPAQFGrGrGW___ R474-m1
R508
KDPEAWSRPQGWYNH
0 1
RIPK3 (human) KDPEAWSRPQGWYNH R508
RIPK3 (mouse) YDQAQFGrGrGWQPF R477-m2
RIPK3 (rat) KEPAQFGRGrGW___ R474
Q510
PEAWSRPQGWYNHSG
0 1
RIPK3 (human) PEAWSRPQGWYNHSG Q510
RIPK3 (mouse) QAQFGrGRGWQPFHK R479
RIPK3 (rat) PAQFGrGrGW_____ R476-m1
Q510
PEAWSRPQGWYNHSG
0 1
RIPK3 (human) PEAWSRPQGWYNHSG Q510
RIPK3 (mouse) QAQFGrGrGWQPFHK R479-m2
RIPK3 (rat) PAQFGrGRGW_____ R476
K518-ub
GWYNHSGk_______
Downstream
1 1
Effects on Modified Protein
  • phosphorylation
RIPK3 (human) GWYNHSGk_______ K518-ub
RIPK3 (mouse) gap -
RIPK3 (rat) gap -