Other Species / Isoforms
  RIPK2 (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

  HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
K17-ub
LPTIPYHkLADLRyL
0 1
RIPK2 (human) LPTIPYHkLADLRyL K17-ub
RIPK2 iso2 (human) gap -
RIPK2 (mouse) LPPIPYHKLADLHYL K17
RIPK2 (rat) LPHIPYHKLADLHYL K17
Y23-p
HkLADLRyLSrGASG
0 1
RIPK2 (human) HkLADLRyLSrGASG Y23-p
RIPK2 iso2 (human) gap -
RIPK2 (mouse) HKLADLHYLSRGASG Y23
RIPK2 (rat) HKLADLHYLSRGASG Y23
R26-m1
ADLRyLSrGASGTVS
0 1
RIPK2 (human) ADLRyLSrGASGTVS R26-m1
RIPK2 iso2 (human) gap -
RIPK2 (mouse) ADLHYLSRGASGTVS R26
RIPK2 (rat) ADLHYLSRGASGTVS R26
S168-p
KIADFGLsKWRMMsL
0 5
RIPK2 (human) KIADFGLsKWRMMsL S168-p
RIPK2 iso2 (human) KIADFGLSKWRMMSL S31
RIPK2 (mouse) KIADFGLSKWRMMSL S168
RIPK2 (rat) KIADFGLSKWRMMSL S168
S174-p
LsKWRMMsLsQsRss
Upstream
1 4
Kinase, in vitro:
  • RIPK2 (human)
RIPK2 (human) LsKWRMMsLsQsRss S174-p
RIPK2 iso2 (human) LSKWRMMSLSQSRSS S37
RIPK2 (mouse) LSKWRMMSLsQsRsy S174
RIPK2 (rat) LSKWRMMSLSQSRSY S174
S176-p
KWRMMsLsQsRsskS
Upstream
Downstream
4 39
RIPK2 (human)
S176-p
Effects on Modified Protein
  • enzymatic activity, induced
Effects on Biological Processes:
  • signaling pathway regulation
  • transcription, inhibited
Kinase, in vitro:
  • RIPK2 (human)
Putative in vivo kinases:
  • RIPK2 (human)
Treatment
  • bacterial infection
  • Fas
  • gefitinib
  • GSK583
  • LPS
view more >
RIPK2 (human) KWRMMsLsQsRsskS S176-p
RIPK2 iso2 (human) KWRMMSLSQSRSSKS S39
RIPK2 (mouse) KWRMMSLsQsRsyKS S176-p
RIPK2 (rat) KWRMMSLSQSRSYKS S176
S178-p
RMMsLsQsRsskSAP
Upstream
1 18
Kinase, in vitro:
  • RIPK2 (human)
Treatment
  • taxol
RIPK2 (human) RMMsLsQsRsskSAP S178-p
RIPK2 iso2 (human) RMMSLSQSRSSKSAP S41
RIPK2 (mouse) RMMSLsQsRsyKSAP S178-p
RIPK2 (rat) RMMSLSQSRSYKSAP S178
S180-p
MsLsQsRsskSAPEG
Upstream
1 2
Kinase, in vitro:
  • RIPK2 (human)
RIPK2 (human) MsLsQsRsskSAPEG S180-p
RIPK2 iso2 (human) MSLSQSRSSKSAPEG S43
RIPK2 (mouse) MSLsQsRsyKSAPEG S180-p
RIPK2 (rat) MSLSQSRSYKSAPEG S180
S181-p
sLsQsRsskSAPEGG
Upstream
1 3
Kinase, in vitro:
  • RIPK2 (human)
RIPK2 (human) sLsQsRsskSAPEGG S181-p
RIPK2 iso2 (human) SLSQSRSSKSAPEGG S44
RIPK2 (mouse) SLsQsRsyKSAPEGG Y181-p
RIPK2 (rat) SLSQSRSYKSAPEGG Y181
K182-ub
LsQsRsskSAPEGGT
0 2
RIPK2 (human) LsQsRsskSAPEGGT K182-ub
RIPK2 iso2 (human) LSQSRSSKSAPEGGT K45
RIPK2 (mouse) LsQsRsyKSAPEGGT K182
RIPK2 (rat) LSQSRSYKSAPEGGT K182
K203-ub
ENYEPGQkSRASIkH
0 3
RIPK2 (human) ENYEPGQkSRASIkH K203-ub
RIPK2 iso2 (human) ENYEPGQKSRASIKH K66
RIPK2 (mouse) ENYEPGQkSRASVkH K203-ub
RIPK2 (rat) ENYEPGQKSRASVKH K203
K209-ub
QkSRASIkHDIYSYA
Upstream
Downstream
3 1
Effects on Modified Protein
  • molecular association, regulation
Effects on Biological Processes:
  • signaling pathway regulation
Regulatory protein:
  • NOD1 (human)
  • NOD2 (human)
  • TNFAIP3 (human)
view more >
RIPK2 (human) QkSRASIkHDIYSYA K209-ub
RIPK2 iso2 (human) QKSRASIKHDIYSYA K72
RIPK2 (mouse) QkSRASVkHDIYSYA K209-ub
RIPK2 (rat) QKSRASVKHDIYSYA K209
S319-p
TKLQSVSsAIHLCDK
0 1
RIPK2 (human) TKLQSVSsAIHLCDK S319-p
RIPK2 iso2 (human) TKLQSVSSAIHLCDK S182
RIPK2 (mouse) AKIQSSSSTIHLCDK S319
RIPK2 (rat) SKIQSASSTIHLCDK S319
S332
DKKKMELSLNIPVNH
0 2
RIPK2 (human) DKKKMELSLNIPVNH S332
RIPK2 iso2 (human) DKKKMELSLNIPVNH S195
RIPK2 (mouse) CDKKMDLsLNIPANH S331-p
RIPK2 (rat) CDKKMDLSLNIPASH S331
S345-p
NHGPQEEsCGSSQLH
0 2
RIPK2 (human) NHGPQEEsCGSSQLH S345-p
RIPK2 iso2 (human) NHGPQEESCGSSQLH S208
RIPK2 (mouse) NHPPQEESCGSSLLS S344
RIPK2 (rat) SHPPQEESCGSSLLS S344
S357-p
QLHENSGsPETSRsL
0 4
RIPK2 (human) QLHENSGsPETSRsL S357-p
RIPK2 iso2 (human) QLHENSGSPETSRSL S220
RIPK2 (mouse) LLSRNTGsPGPsRSL S356-p
RIPK2 (rat) LLSRNAGSPGTSRSL S356
S361
NSGsPETSRsLPAPQ
0 1
RIPK2 (human) NSGsPETSRsLPAPQ S361
RIPK2 iso2 (human) NSGSPETSRSLPAPQ S224
RIPK2 (mouse) NTGsPGPsRSLsAPQ S360-p
RIPK2 (rat) NAGSPGTSRSLSAPQ S360
S363-p
GsPETSRsLPAPQDN
Upstream
0 12
Treatment
  • vemurafenib
RIPK2 (human) GsPETSRsLPAPQDN S363-p
RIPK2 iso2 (human) GSPETSRSLPAPQDN S226
RIPK2 (mouse) GsPGPsRSLsAPQDK S362
RIPK2 (rat) GSPGTSRSLSAPQDK S362
P365
PETSRsLPAPQDNDF
0 6
RIPK2 (human) PETSRsLPAPQDNDF P365
RIPK2 iso2 (human) PETSRSLPAPQDNDF P228
RIPK2 (mouse) PGPsRSLsAPQDKGF S364-p
RIPK2 (rat) PGTSRSLSAPQDKGF S364
S374-p
PQDNDFLsRKAQDCy
0 2
RIPK2 (human) PQDNDFLsRKAQDCy S374-p
RIPK2 iso2 (human) PQDNDFLSRKAQDCY S237
RIPK2 (mouse) PQDKGFLsGAPQDCS S373-p
RIPK2 (rat) PQDKGFFHGGPQDCS H373
Y381-p
sRKAQDCyFMkLHHC
Upstream
0 374
Treatment
  • dasatinib
  • ephrin_B1
  • ephrin_B2
  • HGF
view more >
RIPK2 (human) sRKAQDCyFMkLHHC Y381-p
RIPK2 iso2 (human) SRKAQDCYFMKLHHC Y244
RIPK2 (mouse) sGAPQDCSSLKAHHC S380
RIPK2 (rat) HGGPQDCSSSKAYHC S380
K384-m1
AQDCyFMkLHHCPGN
0 1
RIPK2 (human) AQDCyFMkLHHCPGN K384-m1
RIPK2 iso2 (human) AQDCYFMKLHHCPGN K247
RIPK2 (mouse) PQDCSSLKAHHCPGN K383
RIPK2 (rat) PQDCSSSKAYHCPGN K383
S393-p
HHCPGNHsWDSTIsG
Upstream
0 7
Treatment
  • ischemia
RIPK2 (human) HHCPGNHsWDSTIsG S393-p
RIPK2 iso2 (human) HHCPGNHSWDSTISG S256
RIPK2 (mouse) HHCPGNHsWDGIVsV S392-p
RIPK2 (rat) YHCPGNHSWDGIISV S392
S399-p
HsWDSTIsGSQRAAF
0 2
RIPK2 (human) HsWDSTIsGSQRAAF S399-p
RIPK2 iso2 (human) HSWDSTISGSQRAAF S262
RIPK2 (mouse) HsWDGIVsVPPGAAF S398-p
RIPK2 (rat) HSWDGIISVSQEAAF S398
K410-ub
RAAFCDHkttPCSSA
0 1
RIPK2 (human) RAAFCDHkttPCSSA K410-ub
RIPK2 iso2 (human) RAAFCDHKTTPCSSA K273
RIPK2 (mouse) GAAFCDRRAssCsLA R409
RIPK2 (rat) EAAFCDRRAssCsLT R409
T411-p
AAFCDHkttPCSSAI
Upstream
0 2
Treatment
  • MG132
  • MG132_withdrawal
RIPK2 (human) AAFCDHkttPCSSAI T411-p
RIPK2 iso2 (human) AAFCDHKTTPCSSAI T274
RIPK2 (mouse) AAFCDRRAssCsLAV A410
RIPK2 (rat) AAFCDRRAssCsLTV A410
T412-p
AFCDHkttPCSSAII
0 15
RIPK2 (human) AFCDHkttPCSSAII T412-p
RIPK2 iso2 (human) AFCDHKTTPCSSAII T275
RIPK2 (mouse) AFCDRRAssCsLAVI S411-p
RIPK2 (rat) AFCDRRAssCsLTVI S411-p
P413
FCDHkttPCSSAIIN
0 7
RIPK2 (human) FCDHkttPCSSAIIN P413
RIPK2 iso2 (human) FCDHKTTPCSSAIIN P276
RIPK2 (mouse) FCDRRAssCsLAVIs S412-p
RIPK2 (rat) FCDRRAssCsLTVIR S412-p
S415
DHkttPCSSAIINPL
0 5
RIPK2 (human) DHkttPCSSAIINPL S415
RIPK2 iso2 (human) DHKTTPCSSAIINPL S278
RIPK2 (mouse) DRRAssCsLAVIsPF S414-p
RIPK2 (rat) DRRAssCsLTVIRPL S414-p
N420
PCSSAIINPLSTAGN
0 1
RIPK2 (human) PCSSAIINPLSTAGN N420
RIPK2 iso2 (human) PCSSAIINPLSTAGN N283
RIPK2 (mouse) sCsLAVIsPFLVEKG S419-p
RIPK2 (rat) sCsLTVIRPLLVEKS R419
S428-p
PLSTAGNsERLQPGI
0 1
RIPK2 (human) PLSTAGNsERLQPGI S428-p
RIPK2 iso2 (human) PLSTAGNSERLQPGI S291
RIPK2 (mouse) PFLVEKGSERPPIGI S427
RIPK2 (rat) PLLVEKSSERPQPGI S427
Y474-p
DLIMKEDyELVSTkP
Upstream
Downstream
5 1
Effects on Modified Protein
  • enzymatic activity, induced
  • molecular association, regulation
  • protein degradation
  • ubiquitination
Effects on Biological Processes:
  • signaling pathway regulation
  • transcription, induced
Kinase, in vitro:
  • FGR (human)
  • RIPK2 (human)
Putative in vivo kinases:
  • FGR (human)
  • RIPK2 (human)
Regulatory protein:
  • NOD2 (human)
Treatment
  • antibody
  • bacterial infection
  • BSA
  • erlotinib
  • Fas
  • gefitinib
  • MOD
  • siRNA
view more >
RIPK2 (human) DLIMKEDyELVSTkP Y474-p
RIPK2 iso2 (human) DLIMKEDYELVSTKP Y337
RIPK2 (mouse) DLIMKEDYELISTKP Y473
RIPK2 (rat) DLIMKEDYELISTKP Y473
K480-ub
DyELVSTkPTRTSKV
0 1
RIPK2 (human) DyELVSTkPTRTSKV K480-ub
RIPK2 iso2 (human) DYELVSTKPTRTSKV K343
RIPK2 (mouse) DYELISTKPTRTSKV K479
RIPK2 (rat) DYELISTKPTRTAKV K479
K508-ub
FAKVIVQkLKDNKQM
0 1
RIPK2 (human) FAKVIVQkLKDNKQM K508-ub
RIPK2 iso2 (human) FAKVIVQKLKDNKQM K371
RIPK2 (mouse) FAKVVVQKLKDNKQL K507
RIPK2 (rat) FARVIVQKLKDNKQM K507
S527-p
YPEILVVsRsPsLNL
0 12
RIPK2 (human) YPEILVVsRsPsLNL S527-p
RIPK2 iso2 (human) YPEILVVSRSPSLNL S390
RIPK2 (mouse) YPEVPVLSKAPPSNF S526
RIPK2 (rat) YPEVLLVSRTPSSNV S526
S529-p
EILVVsRsPsLNLLQ
Upstream
0 10
Treatment
  • nocodazole
RIPK2 (human) EILVVsRsPsLNLLQ S529-p
RIPK2 iso2 (human) EILVVSRSPSLNLLQ S392
RIPK2 (mouse) EVPVLSKAPPSNFPQ A528
RIPK2 (rat) EVLLVSRTPSSNVLQ T528
S531-p
LVVsRsPsLNLLQNk
Upstream
0 34
Treatment
  • angiotensin_2
  • ischemia
  • MG132_withdrawal
  • nocodazole
view more >
RIPK2 (human) LVVsRsPsLNLLQNk S531-p
RIPK2 iso2 (human) LVVSRSPSLNLLQNK S394
RIPK2 (mouse) PVLSKAPPSNFPQNK P530
RIPK2 (rat) LLVSRTPSSNVLQNK S530
K538-ub
sLNLLQNksM_____
0 1
RIPK2 (human) sLNLLQNksM_____ K538-ub
RIPK2 iso2 (human) SLNLLQNKSM_____ K401
RIPK2 (mouse) PSNFPQNKsL_____ K537
RIPK2 (rat) SSNVLQNKTL_____ K537
S539-p
LNLLQNksM______
Upstream
0 8
Treatment
  • MG132_withdrawal
RIPK2 (human) LNLLQNksM______ S539-p
RIPK2 iso2 (human) LNLLQNKSM______ S402
RIPK2 (mouse) SNFPQNKsL______ S538-p
RIPK2 (rat) SNVLQNKTL______ T538