Other Species / Isoforms
  iNOS (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

  HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
S50-p
DLQYHNLsKQQNESP
0 1
iNOS (human) DLQYHNLsKQQNESP S50-p
iNOS (mouse) gap -
iNOS (rat) gap -
S70-p
TGKKSPEsLVKLDAt
0 1
iNOS (human) TGKKSPEsLVKLDAt S70-p
iNOS (mouse) TAQNVPESLDKLHVT S65
iNOS (rat) TAQNVPESLDKLHVT S67
T77-p
sLVKLDAtPLSSPRH
0 1
iNOS (human) sLVKLDAtPLSSPRH T77-p
iNOS (mouse) SLDKLHVTSTRPQYV T72
iNOS (rat) SLDKLHVTPSTRPQH T74
S112-p
KGILTCRsKSCLGSI
0 1
iNOS (human) KGILTCRsKSCLGSI S112-p
iNOS (mouse) TSDFTCKSKSCLGSI S106
iNOS (rat) TSDISCKSKLCMGSI S109
S124-p
GSIMTPKsLtRGPRD
0 1
iNOS (human) GSIMTPKsLtRGPRD S124-p
iNOS (mouse) GSIMNPKSLTRGPRD S118
iNOS (rat) GSIMNSKSLTRGPRD S121
T126-p
IMTPKsLtRGPRDKP
0 2
iNOS (human) IMTPKsLtRGPRDKP T126-p
iNOS (mouse) IMNPKSLTRGPRDKP T120
iNOS (rat) IMNSKSLTRGPRDKP T123
Y151-p
IEFVNQYyGSFKEAK
Upstream
Downstream
3 0
Effects on Modified Protein
  • enzymatic activity, inhibited
  • intracellular localization
Kinase, in vitro:
  • Src (human)
Putative in vivo kinases:
  • Src (human)
iNOS (human) IEFVNQYyGSFKEAK Y151-p
iNOS (mouse) IEFINQYYGSFKEAK Y145
iNOS (rat) IEFINQYyGSFKEAK Y148-p
Y267-p
WNAQLIRyAGyQMPD
0 1
iNOS (human) WNAQLIRyAGyQMPD Y267-p
iNOS (mouse) WNSQLIRYAGYQMPD Y261
iNOS (rat) WNSQLIRYAGYQMPD Y264
Y270-p
QLIRyAGyQMPDGSI
0 1
iNOS (human) QLIRyAGyQMPDGSI Y270-p
iNOS (mouse) QLIRYAGYQMPDGTI Y264
iNOS (rat) QLIRYAGYQMPDGTI Y267
S425-p
INIAVLHsFQKQNVT
0 1
iNOS (human) INIAVLHsFQKQNVT S425-p
iNOS (mouse) INVAVLHSFQkQNVT S419
iNOS (rat) INAAVLHSFQKQNVT S422
K428
AVLHsFQKQNVTIMD
0 1
iNOS (human) AVLHsFQKQNVTIMD K428
iNOS (mouse) AVLHSFQkQNVTIMD K422-m1
iNOS (rat) AVLHSFQKQNVTIMD K425
Y446-p
AAESFMKyMQNEyRs
0 1
iNOS (human) AAESFMKyMQNEyRs Y446-p
iNOS (mouse) ASESFMKHMQNEYRA H440
iNOS (rat) ASESFMKHMQNEYRA H443
Y451-p
MKyMQNEyRsRGGCP
0 1
iNOS (human) MKyMQNEyRsRGGCP Y451-p
iNOS (mouse) MKHMQNEYRARGGCP Y445
iNOS (rat) MKHMQNEYRARGGCP Y448
S453-p
yMQNEyRsRGGCPAD
0 1
iNOS (human) yMQNEyRsRGGCPAD S453-p
iNOS (mouse) HMQNEYRARGGCPAD A447
iNOS (rat) HMQNEYRARGGCPAD A450
K516-ub
KRREIPLkVLVKAVL
0 1
iNOS (human) KRREIPLkVLVKAVL K516-ub
iNOS (mouse) RRREIRFRVLVKVVF R510
iNOS (rat) RRREIRFTVLVKAVF T513
P567
LFSCAFNPKVVCMDK
0 1
iNOS (human) LFSCAFNPKVVCMDK P567
iNOS (mouse) LFSYAFNTKVVCMDQ T561
iNOS (rat) LFSYAFNtKVVCMEQ T564-p
Y575-p
KVVCMDKyRLSCLEE
0 1
iNOS (human) KVVCMDKyRLSCLEE Y575-p
iNOS (mouse) KVVCMDQYKASTLEE Y569
iNOS (rat) KVVCMEQYKANTLEE Y572
K604-ac
DCPGNGEkLKKSLFM
0 1
iNOS (human) DCPGNGEkLKKSLFM K604-ac
iNOS (mouse) DCPSNGQTLKKSLFM T598
iNOS (rat) DCPSNGQTLKKSLFM T601
R670-m2
SGQEDAFrSWAVQTF
0 1
iNOS (human) SGQEDAFrSWAVQTF R670-m2
iNOS (mouse) SGQEDAFRSWAVQTF R664
iNOS (rat) SGQEDAFRSWAVQTF R667
D714
HHYRLVQDSQPLDLS
0 1
iNOS (human) HHYRLVQDSQPLDLS D714
iNOS (mouse) QQYRLIQsPEPLDLN S708-p
iNOS (rat) EQYKLTQSPESLDLN S711
K722
SQPLDLSKALSSMHA
0 1
iNOS (human) SQPLDLSKALSSMHA K722
iNOS (mouse) PEPLDLNrALSSIHA R716-m1
iNOS (rat) PESLDLNKALSSIHA K719
S739
VFTMRLKSRQNLQsP
1 0
iNOS (human) VFTMRLKSRQNLQsP S739
iNOS (mouse) VFTMRLKsQQNLQSE S733-p
iNOS (rat) VFTMRLKSLQNLQSE S736
S745-p
KSRQNLQsPTSSRAT
Upstream
Downstream
1 1
Effects on Modified Protein
  • enzymatic activity, induced
Kinase, in vitro:
  • ERK1 (human)
Putative in vivo kinases:
  • ERK1 (human)
Treatment
  • DAKD
  • PD98059
iNOS (human) KSRQNLQsPTSSRAT S745-p
iNOS (mouse) KsQQNLQSEKSSRTT S739
iNOS (rat) KSLQNLQSEKSSRTT S742
Y868-p
ALCQPSEySKWKFTN
0 1
iNOS (human) ALCQPSEySKWKFTN Y868-p
iNOS (mouse) ALCQPSEYNDWKFSN Y862
iNOS (rat) ALCQPSEYNDWKFSN Y865
S892-p
EFPSLRVsAGFLLsQ
0 2
iNOS (human) EFPSLRVsAGFLLsQ S892-p
iNOS (mouse) EFPSLHVPAAFLLSQ P886
iNOS (rat) EFPSLRVPAAFLLSQ P889
S898-p
VsAGFLLsQLPILKP
0 2
iNOS (human) VsAGFLLsQLPILKP S898-p
iNOS (mouse) VPAAFLLSQLPILKP S892
iNOS (rat) VPAAFLLSQLPILKP S895
S909
ILKPRFYSISSSRDH
1 0
iNOS (human) ILKPRFYSISSSRDH S909
iNOS (mouse) ILKPRYYsISSSQDH S903-p
iNOS (rat) ILKPRYYSISSSQDH S906
R1047
AVHTAYSRLPGKPKV
0 1
iNOS (human) AVHTAYSRLPGKPKV R1047
iNOS (mouse) QVHTGYSrLPGKPKV R1041-m1
iNOS (rat) QVHTGYSRLPGKPKV R1044
Y1055-p
LPGKPKVyVQDILRQ
Upstream
Downstream
1 6
Effects on Modified Protein
  • protein stabilization
Putative in vivo kinases:
  • Src (human)
Regulatory protein:
  • EGFR (human)
Treatment
  • cytokines
  • EGF
  • vanadate
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iNOS (human) LPGKPKVyVQDILRQ Y1055-p
iNOS (mouse) LPGKPKVyVQDILQK Y1049-p
iNOS (rat) LPGKPKVyVQDILQK Y1052-p
Y1123-p
QLKSQKRyHEDIFGA
0 1
iNOS (human) QLKSQKRyHEDIFGA Y1123-p
iNOS (mouse) QLKSQKRYHEDIFGA Y1117
iNOS (rat) QLKSQKRYHEDIFGA Y1120
Y1134-p
IFGAVFPyEAKKDRV
0 1
iNOS (human) IFGAVFPyEAKKDRV Y1134-p
iNOS (mouse) IFGAVFSYGAKKGsA Y1128
iNOS (rat) IFGAVFSYGAKKGNT Y1131
R1140
PyEAKKDRVAVQPSS
0 1
iNOS (human) PyEAKKDRVAVQPSS R1140
iNOS (mouse) SYGAKKGsALEEPKA S1134-p
iNOS (rat) SYGAKKGNTLEEPKG N1137