Other Species / Isoforms
  RIPK1 (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

 HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
S6-p
__MQPDMsLNVIKMk
0 2
RIPK1 (human) __MQPDMsLNVIKMk S6-p
RIPK1 iso2 (human) __MQPDMSLNVIKMK S6
RIPK1 (mouse) __MQPDMSLDNIKMA S6
RIPK1 (rat) __MQPDMSLDNIKMA S6
K13-ub
sLNVIKMkssDFLEs
0 2
RIPK1 (human) sLNVIKMkssDFLEs K13-ub
RIPK1 iso2 (human) SLNVIKMKSSDFLES K13
RIPK1 (mouse) SLDNIKMAssDLLEK A13
RIPK1 (rat) SLDNIKMASDDLLER A13
S14-p
LNVIKMkssDFLEsA
Upstream
1 1
Kinase, in vitro:
  • RIPK1 (human)
RIPK1 (human) LNVIKMkssDFLEsA S14-p
RIPK1 iso2 (human) LNVIKMKSSDFLESA S14
RIPK1 (mouse) LDNIKMAssDLLEKT S14-p
RIPK1 (rat) LDNIKMASDDLLERK S14
S15-p
NVIKMkssDFLEsAE
Upstream
1 1
Kinase, in vitro:
  • RIPK1 (human)
RIPK1 (human) NVIKMkssDFLEsAE S15-p
RIPK1 iso2 (human) NVIKMKSSDFLESAE S15
RIPK1 (mouse) DNIKMAssDLLEKTD S15-p
RIPK1 (rat) DNIKMASDDLLERKD D15
S20-p
kssDFLEsAELDsGG
Upstream
0 1
Kinase, in vitro:
  • RIPK1 (human)
RIPK1 (human) kssDFLEsAELDsGG S20-p
RIPK1 iso2 (human) KSSDFLESAELDSGG S20
RIPK1 (mouse) AssDLLEKTDLDSGG K20
RIPK1 (rat) ASDDLLERKDLDSGG R20
S25-p
LEsAELDsGGFGKVs
0 3
RIPK1 (human) LEsAELDsGGFGKVs S25-p
RIPK1 iso2 (human) LESAELDSGGFGKVS S25
RIPK1 (mouse) LEKTDLDSGGFGKVS S25
RIPK1 (rat) LERKDLDSGGFGKVS S25
S32-p
sGGFGKVsLCFHRtQ
0 1
RIPK1 (human) sGGFGKVsLCFHRtQ S32-p
RIPK1 iso2 (human) SGGFGKVSLCFHRTQ S32
RIPK1 (mouse) SGGFGKVSLCYHRSH S32
RIPK1 (rat) SGGFGKVSLCFHRTH S32
T38-p
VsLCFHRtQGLMIMK
0 2
RIPK1 (human) VsLCFHRtQGLMIMK T38-p
RIPK1 iso2 (human) VSLCFHRTQGLMIMK T38
RIPK1 (mouse) VSLCYHRSHGFVILK S38
RIPK1 (rat) VSLCFHRTHGFVILK T38
K49-ub
MIMKTVYkGPNCIEH
0 1
RIPK1 (human) MIMKTVYkGPNCIEH K49-ub
RIPK1 iso2 (human) MIMKTVYKGPNCIEH K49
RIPK1 (mouse) under review -
RIPK1 (rat) under review -
K105-ub
GNLMHVLkAEMSTPL
0 1
RIPK1 (human) GNLMHVLkAEMSTPL K105-ub
RIPK1 iso2 (human) GNLMHVLKAEIADLG K105
RIPK1 (mouse) GNLMHVLKTQIDVPL K105
RIPK1 (rat) GNLMHVLKTKESVPL K105
K115-ub
MSTPLSVkGRIILEI
1 2
RIPK1 (human) MSTPLSVkGRIILEI K115-ub
RIPK1 iso2 (human) gap -
RIPK1 (mouse) IDVPLSLkGRIIVEA K115-ub
RIPK1 (rat) ESVPLSVKGRIIVEI K115
K137-ub
HGKGVIHkDLkPENI
0 1
RIPK1 (human) HGKGVIHkDLkPENI K137-ub
RIPK1 iso2 (human) under review -
RIPK1 (mouse) HDKGVIHKDLKPENI K137
RIPK1 (rat) HDEGVIHKDLKPENI K137
K140-ub
GVIHkDLkPENILVD
0 2
RIPK1 (human) GVIHkDLkPENILVD K140-ub
RIPK1 iso2 (human) under review -
RIPK1 (mouse) GVIHKDLKPENILVD K140
RIPK1 (rat) GVIHKDLKPENILVD K140
K153-ub
VDNDFHIkIADLGLA
0 1
RIPK1 (human) VDNDFHIkIADLGLA K153-ub
RIPK1 iso2 (human) under review -
RIPK1 (mouse) VDRDFHIKIADLGVA K153
RIPK1 (rat) VDRDFHIKIADLGVA K153
S161-p
IADLGLAsFkMWskL
Upstream
Downstream
1 1
Effects on Modified Protein
  • enzymatic activity, induced
Kinase, in vitro:
  • RIPK1 (human)
RIPK1 (human) IADLGLAsFkMWskL S161-p
RIPK1 iso2 (human) IADLGLASFKMWSKL S115
RIPK1 (mouse) IADLGVASFKTWsKL S161
RIPK1 (rat) IADLGVASFKTWSKL S161
K163-ub
DLGLAsFkMWskLNN
0 1
RIPK1 (human) DLGLAsFkMWskLNN K163-ub
RIPK1 iso2 (human) DLGLASFKMWSKLNN K117
RIPK1 (mouse) DLGVASFKTWsKLTK K163
RIPK1 (rat) DLGVASFKTWSKLTK K163
S166-p
LAsFkMWskLNNEEH
Upstream
11 2
RIPK1 (human)
S166-p
RIPK1 (mouse)
S166-p
RIPK1 (rat)
S166-p
Kinase, in vitro:
  • RIPK1 (human)
RIPK1 (human) LAsFkMWskLNNEEH S166-p
RIPK1 iso2 (human) LASFKMWSKLNNEEH S120
RIPK1 (mouse) VASFKTWsKLTKEKD S166-p
RIPK1 (rat) VASFKTWSKLTKEEH S166
K167-ub
AsFkMWskLNNEEHN
0 2
RIPK1 (human) AsFkMWskLNNEEHN K167-ub
RIPK1 iso2 (human) ASFKMWSKLNNEEHN K121
RIPK1 (mouse) ASFKTWsKLTKEKDN K167
RIPK1 (rat) ASFKTWSKLTKEEHN K167
K184-ub
REVDGTAkkNGGTLY
0 1
RIPK1 (human) REVDGTAkkNGGTLY K184-ub
RIPK1 iso2 (human) REVDGTAKKNGGTLY K138
RIPK1 (mouse) EVSSTTKKNNGGTLY K185
RIPK1 (rat) REASSVTKKNGGTLY K184
K185-ub
EVDGTAkkNGGTLYY
0 1
RIPK1 (human) EVDGTAkkNGGTLYY K185-ub
RIPK1 iso2 (human) EVDGTAKKNGGTLYY K139
RIPK1 (mouse) under review -
RIPK1 (rat) EASSVTKKNGGTLYY K185
E234
PYENAICEQQLIMCI
1 1
RIPK1 (human) PYENAICEQQLIMCI E234
RIPK1 iso2 (human) PYENAICEQQLIMCI E188
RIPK1 (mouse) PYENVICtEQFVICI T235-p
RIPK1 (rat) PYENVICTEQFLVCI T234
S262-p
YCPREIIsLMKLCWE
1 0
RIPK1 (human) YCPREIIsLMKLCWE S262-p
RIPK1 iso2 (human) under review -
RIPK1 (mouse) under review -
RIPK1 (rat) under review -
K284-ub
TFPGIEEkFRPFYLs
0 1
RIPK1 (human) TFPGIEEkFRPFYLs K284-ub
RIPK1 iso2 (human) TFPGIEEKFRPFYLS K238
RIPK1 (mouse) TFLGIEEEFRPFYLS E285
RIPK1 (rat) TFFGIEKEFKPFYLS E284
S291-p
kFRPFYLsQLEEsVE
1 0
RIPK1 (human) kFRPFYLsQLEEsVE S291-p
RIPK1 iso2 (human) under review -
RIPK1 (mouse) under review -
RIPK1 (rat) under review -
S296-p
YLsQLEEsVEEDVks
1 1
RIPK1 (human) YLsQLEEsVEEDVks S296-p
RIPK1 iso2 (human) YLSQLEESVEEDVKS S250
RIPK1 (mouse) YLSHFEEYVEEDVAS Y297
RIPK1 (rat) YLSQFEEYVEEDVAS Y296
K302-ub
EsVEEDVksLKkEYs
0 1
RIPK1 (human) EsVEEDVksLKkEYs K302-ub
RIPK1 iso2 (human) ESVEEDVKSLKKEYS K256
RIPK1 (mouse) EYVEEDVASLKkEyP A303
RIPK1 (rat) EYVEEDVASLKKEYP A302
S303-p
sVEEDVksLKkEYsN
0 2
RIPK1 (human) sVEEDVksLKkEYsN S303-p
RIPK1 iso2 (human) SVEEDVKSLKKEYSN S257
RIPK1 (mouse) YVEEDVASLKkEyPD S304
RIPK1 (rat) YVEEDVASLKKEYPS S303
K306-ub
EDVksLKkEYsNENA
0 2
RIPK1 (human) EDVksLKkEYsNENA K306-ub
RIPK1 iso2 (human) EDVKSLKKEYSNENA K260
RIPK1 (mouse) EDVASLKkEyPDQsP K307-ub
RIPK1 (rat) EDVASLKKEYPSQsP K306
Y308
VksLKkEYsNENAVV
0 1
RIPK1 (human) VksLKkEYsNENAVV Y308
RIPK1 iso2 (human) VKSLKKEYSNENAVV Y262
RIPK1 (mouse) VASLKkEyPDQsPVL Y309-p
RIPK1 (rat) VASLKKEYPSQsPVL Y308
S309-p
ksLKkEYsNENAVVk
0 1
RIPK1 (human) ksLKkEYsNENAVVk S309-p
RIPK1 iso2 (human) KSLKKEYSNENAVVK S263
RIPK1 (mouse) ASLKkEyPDQsPVLQ P310
RIPK1 (rat) ASLKKEYPSQsPVLK P309
N312
KkEYsNENAVVkRMQ
1 30
RIPK1 (human) KkEYsNENAVVkRMQ N312
RIPK1 iso2 (human) KKEYSNENAVVKRMQ N266
RIPK1 (mouse) KkEyPDQsPVLQRMF S313-p
RIPK1 (rat) KKEYPSQsPVLKRMF S312-p
K316-ub
sNENAVVkRMQsLQL
0 4
RIPK1 (human) sNENAVVkRMQsLQL K316-ub
RIPK1 iso2 (human) SNENAVVKRMQSLQL K270
RIPK1 (mouse) PDQsPVLQRMFsLQH Q317
RIPK1 (rat) PSQsPVLKRMFsLQH K316
S320-p
AVVkRMQsLQLdCVA
Upstream
Downstream
7 60
RIPK1 (mouse)
S321-p
Effects on Modified Protein
  • molecular association, regulation
Effects on Biological Processes:
  • apoptosis, inhibited
Kinase, in vitro:
  • MAPKAPK2 (human)
Putative in vivo kinases:
  • MAPKAPK2 (human)
Treatment
  • anti-CD3
  • ischemia
  • PF3644022
  • TNF
RIPK1 (human) AVVkRMQsLQLdCVA S320-p
RIPK1 iso2 (human) AVVKRMQSLQLDCVA S274
RIPK1 (mouse) PVLQRMFsLQHDCVP S321-p
RIPK1 (rat) PVLKRMFsLQHDCVP S320-p
D324-ca
RMQsLQLdCVAVPss
1 0
RIPK1 (human) RMQsLQLdCVAVPss D324-ca
RIPK1 iso2 (human) RMQSLQLDCVAVPSS D278
RIPK1 (mouse) RMFsLQHDCVPLPPs D325
RIPK1 (rat) RMFsLQHDCVPLPPS D324
S330-p
LdCVAVPssRsNsAt
Upstream
0 4
Treatment
  • anti-CD3
RIPK1 (human) LdCVAVPssRsNsAt S330-p
RIPK1 iso2 (human) LDCVAVPSSRSNSAT S284
RIPK1 (mouse) HDCVPLPPsRsNsEQ P331
RIPK1 (rat) HDCVPLPPSRSNSEQ P330
S331-p
dCVAVPssRsNsAtE
1 5
RIPK1 (human) dCVAVPssRsNsAtE S331-p
RIPK1 iso2 (human) DCVAVPSSRSNSATE S285
RIPK1 (mouse) DCVPLPPsRsNsEQP S332-p
RIPK1 (rat) DCVPLPPSRSNSEQP S331
S333-p
VAVPssRsNsAtEQP
2 2
RIPK1 (human) VAVPssRsNsAtEQP S333-p
RIPK1 iso2 (human) VAVPSSRSNSATEQP S287
RIPK1 (mouse) VPLPPsRsNsEQPGS S334-p
RIPK1 (rat) VPLPPSRSNSEQPGS S333
S335-p
VPssRsNsAtEQPGS
4 1
RIPK1 (human) VPssRsNsAtEQPGS S335-p
RIPK1 iso2 (human) VPSSRSNSATEQPGS S289
RIPK1 (mouse) LPPsRsNsEQPGSLH S336-p
RIPK1 (rat) LPPSRSNSEQPGSLH S335
T337-p
ssRsNsAtEQPGSLH
1 0
RIPK1 (human) ssRsNsAtEQPGSLH T337-p
RIPK1 iso2 (human) under review -
RIPK1 (mouse) under review -
RIPK1 (rat) under review -
S345-p
EQPGSLHssQGLGMG
1 0
RIPK1 (human) EQPGSLHssQGLGMG S345-p
RIPK1 iso2 (human) under review -
RIPK1 (mouse) under review -
RIPK1 (rat) under review -
S346-p
QPGSLHssQGLGMGP
1 0
RIPK1 (human) QPGSLHssQGLGMGP S346-p
RIPK1 iso2 (human) under review -
RIPK1 (mouse) under review -
RIPK1 (rat) under review -
S357-p
GMGPVEEsWFAPSLE
1 0
RIPK1 (human) GMGPVEEsWFAPSLE S357-p
RIPK1 iso2 (human) GMGPVEESWFAPSLE S311
RIPK1 (mouse) QMGPVEESWFSSSPE S356
RIPK1 (rat) PMGPVEESWFSSSPE S355
K377-ub
NEPSLQSkLQDEANy
5 0
RIPK1 (human) NEPSLQSkLQDEANy K377-ub
RIPK1 iso2 (human) NEPSLQSKLQDEANY K331
RIPK1 (mouse) NDRSVQAKLQEEASY K376
RIPK1 (rat) NERSVQAKLQEEASY K375
Y384-p
kLQDEANyHLyGsRM
Upstream
0 296
Treatment
  • ephrin_B1
  • Su11274
RIPK1 (human) kLQDEANyHLyGsRM Y384-p
RIPK1 iso2 (human) KLQDEANYHLYGSRM Y338
RIPK1 (mouse) KLQEEASYHAFGIFA Y383
RIPK1 (rat) KLQEEASYHAFGIFA Y382
Y387-p
DEANyHLyGsRMDRQ
0 213
RIPK1 (human) DEANyHLyGsRMDRQ Y387-p
RIPK1 iso2 (human) DEANYHLYGSRMDRQ Y341
RIPK1 (mouse) EEASYHAFGIFAEKQ F386
RIPK1 (rat) EEASYHAFGIFAEKQ F385
S389-p
ANyHLyGsRMDRQTK
1 4
RIPK1 (human) ANyHLyGsRMDRQTK S389-p
RIPK1 iso2 (human) ANYHLYGSRMDRQTK S343
RIPK1 (mouse) ASYHAFGIFAEKQTK I388
RIPK1 (rat) ASYHAFGIFAEKQTK I387
S416-p
EERRRRVsHDPFAQQ
0 18
RIPK1 (human) EERRRRVsHDPFAQQ S416-p
RIPK1 iso2 (human) EERRRRVSHDPFAQQ S370
RIPK1 (mouse) EERKRRVsHDPFAQQ S415-p
RIPK1 (rat) EERKRRVsHDPFAQQ S414-p
Y426-p
PFAQQRPyENFQNTE
0 36
RIPK1 (human) PFAQQRPyENFQNTE Y426-p
RIPK1 iso2 (human) PFAQQRPYENFQNTE Y380
RIPK1 (mouse) PFAQQRARENIkSAG R425
RIPK1 (rat) PFAQQRVHENVKSAG H424
Q430
QRPyENFQNTEGKGT
0 1
RIPK1 (human) QRPyENFQNTEGKGT Q430
RIPK1 iso2 (human) QRPYENFQNTEGKGT Q384
RIPK1 (mouse) QRARENIkSAGARGH K429-ac
RIPK1 (rat) QRVHENVKSAGAKGL K428
A438
NTEGKGTAYSSAASH
0 2
RIPK1 (human) NTEGKGTAYSSAASH A438
RIPK1 iso2 (human) NTEGKGTAYSSAASH A392
RIPK1 (mouse) SAGARGHsDPSTTSR S437-p
RIPK1 (rat) SAGAKGLPYPSTTSH P436
Y463-p
TSQPQVLyQNNGLys
0 4
RIPK1 (human) TSQPQVLyQNNGLys Y463-p
RIPK1 iso2 (human) TSQPQVLYQNNGLYS Y417
RIPK1 (mouse) SWPATQTVWNNGLYN V459
RIPK1 (rat) ASQIKVPLWNNGVYN L461
Y469-p
LyQNNGLyssHGFGT
0 10
RIPK1 (human) LyQNNGLyssHGFGT Y469-p
RIPK1 iso2 (human) LYQNNGLYSSHGFGT Y423
RIPK1 (mouse) TVWNNGLYNQHGFGT Y465
RIPK1 (rat) PLWNNGVYNHHGFGA Y467
S470-p
yQNNGLyssHGFGTr
0 1
RIPK1 (human) yQNNGLyssHGFGTr S470-p
RIPK1 iso2 (human) YQNNGLYSSHGFGTR S424
RIPK1 (mouse) VWNNGLYNQHGFGTT N466
RIPK1 (rat) LWNNGVYNHHGFGAT N468
S471-p
QNNGLyssHGFGTrP
0 2
RIPK1 (human) QNNGLyssHGFGTrP S471-p
RIPK1 iso2 (human) QNNGLYSSHGFGTRP S425
RIPK1 (mouse) WNNGLYNQHGFGTTG Q467
RIPK1 (rat) WNNGVYNHHGFGATG H469
R477-m1
ssHGFGTrPLDPGtA
0 1
RIPK1 (human) ssHGFGTrPLDPGtA R477-m1
RIPK1 iso2 (human) SSHGFGTRPLDPGTA R431
RIPK1 (mouse) gap -
RIPK1 (rat) gap -
T483-p
TrPLDPGtAGPrVWy
0 1
RIPK1 (human) TrPLDPGtAGPrVWy T483-p
RIPK1 iso2 (human) TRPLDPGTAGPRVWY T437
RIPK1 (mouse) YNQHGFGTTGTGVWY T472
RIPK1 (rat) YNHHGFGATGTGVWY A474
R487-m1
DPGtAGPrVWyRPIP
0 1
RIPK1 (human) DPGtAGPrVWyRPIP R487-m1
RIPK1 iso2 (human) DPGTAGPRVWYRPIP R441
RIPK1 (mouse) GFGTTGTGVWYPPNL G476
RIPK1 (rat) GFGATGTGVWYGPSV G478
Y490-p
tAGPrVWyRPIPSHM
0 3
RIPK1 (human) tAGPrVWyRPIPSHM Y490-p
RIPK1 iso2 (human) TAGPRVWYRPIPSHM Y444
RIPK1 (mouse) TTGTGVWYPPNLSQM Y479
RIPK1 (rat) ATGTGVWYGPSVSQS Y481
N513
PETNYLGNTPTMPFS
0 1
RIPK1 (human) PETNYLGNTPTMPFS N513
RIPK1 iso2 (human) PETNYLGNTPTMPFS N467
RIPK1 (mouse) PETNIPGSTPTMPYF S502
RIPK1 (rat) PETNLPGsIPTMPYI S504-p
K530-ac
PPTDESIkYTIYNST
1 0
RIPK1 (human) PPTDESIkYTIYNST K530-ac
RIPK1 iso2 (human) PPTDESIKYTIYNST K484
RIPK1 (mouse) PVADDLIKYTIFNSS K519
RIPK1 (rat) APPDDSIRCTIYNSS R521
K571-ub
FKEEPAAkYQAIFDN
0 2
RIPK1 (human) FKEEPAAkYQAIFDN K571-ub
RIPK1 iso2 (human) FKEEPAAKYQAIFDN K525
RIPK1 (mouse) CKEESTSRHQAIFDN R556
RIPK1 (rat) CKVESTSRHQAVFAN R558
K585-ub
NTTSLTDkHLDPIRE
0 2
RIPK1 (human) NTTSLTDkHLDPIRE K585-ub
RIPK1 iso2 (human) NTTSLTDKHLDPIRE K539
RIPK1 (mouse) NTTSLTDEHLNPIRE E570
RIPK1 (rat) NTTSLTDKHLNPIRE K572
K596-ub
PIRENLGkHWKNCAR
0 1
RIPK1 (human) PIRENLGkHWKNCAR K596-ub
RIPK1 iso2 (human) PIRENLGKHWKNCAR K550
RIPK1 (mouse) PIRENLGRQWKNCAR R581
RIPK1 (rat) PIRENMGKQWKNCAR K583
K604-ub
HWKNCARkLGFTQsQ
0 2
RIPK1 (human) HWKNCARkLGFTQsQ K604-ub
RIPK1 iso2 (human) HWKNCARKLGFTQSQ K558
RIPK1 (mouse) QWKNCARKLGFTESQ K589
RIPK1 (rat) QWKNCARKLGFTESQ K591
S610-p
RkLGFTQsQIDEIDH
0 1
RIPK1 (human) RkLGFTQsQIDEIDH S610-p
RIPK1 iso2 (human) RKLGFTQSQIDEIDH S564
RIPK1 (mouse) RKLGFTESQIDEIDH S595
RIPK1 (rat) RKLGFTESQIDEIDH S597
K627-ub
ERDGLKEkVYQMLQK
0 3
RIPK1 (human) ERDGLKEkVYQMLQK K627-ub
RIPK1 iso2 (human) ERDGLKEKVYQMLQK K581
RIPK1 (mouse) ERDGLKEkVYQMLQK K612-ub
RIPK1 (rat) ERDGLKEKVYQMLQK K614
K642-ac
WVMREGIkGATVGkL
0 1
RIPK1 (human) WVMREGIkGATVGkL K642-ac
RIPK1 iso2 (human) WVMREGIKGATVGKL K596
RIPK1 (mouse) WLMREGTKGATVGKL K627
RIPK1 (rat) WLMREGTKGATVGKL K629
K642-ub
WVMREGIkGATVGkL
0 3
RIPK1 (human) WVMREGIkGATVGkL K642-ub
RIPK1 iso2 (human) WVMREGIKGATVGKL K596
RIPK1 (mouse) WLMREGTKGATVGKL K627
RIPK1 (rat) WLMREGTKGATVGKL K629
K648-ac
IkGATVGkLAQALHQ
0 1
RIPK1 (human) IkGATVGkLAQALHQ K648-ac
RIPK1 iso2 (human) IKGATVGKLAQALHQ K602
RIPK1 (mouse) TKGATVGKLAQALHQ K633
RIPK1 (rat) TKGATVGKLAQALHQ K635
S664-p
SRIDLLSsLIYVSQN
0 1
RIPK1 (human) SRIDLLSsLIYVSQN S664-p
RIPK1 iso2 (human) SRIDLLSSLIYVSQN S618
RIPK1 (mouse) CRIDLLNHLIRASQS H649
RIPK1 (rat) CRTDLLNQLIQASQS Q651