Other Species / Isoforms
  WNK1 (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

  HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
S2-p
______MsGGAAEKQ
0 3
WNK1 (human) ______MsGGAAEKQ S2-p
WNK1 iso2 (human) ______MSGGAAEKQ S2
WNK1 iso4 (human) gap -
WNK1 iso5 (human) ______MSGGAAEKQ S2
WNK1 iso7 (human) ______MSGGAAEKQ S2
WNK1 (mouse) ______MsDGAAEKQ S2-p
WNK1 iso3 (mouse) ______MSDGAAEKQ S2
WNK1 (rat) ______MSDGTAEKQ S2
WNK1 (cow) ______MSGGAADQQ S2
S11-p
GAAEKQSstPGsLFL
0 1
WNK1 (human) GAAEKQSstPGsLFL S11-p
WNK1 iso2 (human) GAAEKQSSTPGSLFL S11
WNK1 iso4 (human) gap -
WNK1 iso5 (human) GAAEKQSSTPGSLFL S11
WNK1 iso7 (human) GAAEKQSSTPGSLFL S11
WNK1 (mouse) GAAEKQSGTPGFLtP G11
WNK1 iso3 (mouse) GAAEKQSGTPGFLTP G11
WNK1 (rat) GTAEKQSGTPGFLSP G11
WNK1 (cow) GAADQQSSAQGSLFL S11
T12-p
AAEKQSstPGsLFLs
0 1
WNK1 (human) AAEKQSstPGsLFLs T12-p
WNK1 iso2 (human) AAEKQSSTPGSLFLS T12
WNK1 iso4 (human) gap -
WNK1 iso5 (human) AAEKQSSTPGSLFLS T12
WNK1 iso7 (human) AAEKQSSTPGSLFLS T12
WNK1 (mouse) AAEKQSGTPGFLtPP T12
WNK1 iso3 (mouse) AAEKQSGTPGFLTPP T12
WNK1 (rat) TAEKQSGTPGFLSPP T12
WNK1 (cow) AADQQSSAQGSLFLS A12
S15-p
KQSstPGsLFLsPPA
Upstream
0 4
Treatment
  • sorbitol
WNK1 (human) KQSstPGsLFLsPPA S15-p
WNK1 iso2 (human) KQSSTPGSLFLSPPA S15
WNK1 iso4 (human) gap -
WNK1 iso5 (human) KQSSTPGSLFLSPPA S15
WNK1 iso7 (human) KQSSTPGSLFLSPPA S15
WNK1 (mouse) gap -
WNK1 iso3 (mouse) gap -
WNK1 (rat) gap -
WNK1 (cow) QQSSAQGSLFLSPPA S15
S19-p
tPGsLFLsPPAPAPK
Upstream
0 32
Treatment
  • nocodazole
WNK1 (human) tPGsLFLsPPAPAPK S19-p
WNK1 iso2 (human) TPGSLFLSPPAPAPK S19
WNK1 iso4 (human) gap -
WNK1 iso5 (human) TPGSLFLSPPAPAPK S19
WNK1 iso7 (human) TPGSLFLSPPAPAPK S19
WNK1 (mouse) SGTPGFLtPPAPVPK T17-p
WNK1 iso3 (mouse) SGTPGFLTPPAPVPK T17
WNK1 (rat) SGTPGFLSPPAPVPK S17
WNK1 (cow) AQGSLFLSPPAPAPK S19
S33-p
KNGSSSDsSVGEKLG
0 1
WNK1 (human) KNGSSSDsSVGEKLG S33-p
WNK1 iso2 (human) KNGSSSDSSVGEKLG S33
WNK1 iso4 (human) gap -
WNK1 iso5 (human) KNGSSSDSSVGEKLG S33
WNK1 iso7 (human) KNGSSSDSSVGEKLG S33
WNK1 (mouse) KNGSSSDSSVGEKLG S31
WNK1 iso3 (mouse) KNGSSSDSSVGEKLG S31
WNK1 (rat) KNGSSSDSSVGEKLG S31
WNK1 (cow) KNGSSSDSSVGEKLG S33
T60-p
EYRRRRHtMDKDSrG
Upstream
Downstream
8 211
WNK1 (human)
T60-p
WNK1 (mouse)
T58-p
WNK1 (rat)
T58-p
Effects on Modified Protein
  • activity, induced
Effects on Biological Processes:
  • carcinogenesis, induced
  • cell growth, induced
Kinase, in vitro:
  • Akt1 (human)
  • MSK1 (human)
  • SGK1 (human)
view more >
Putative in vivo kinases:
  • Akt1 (human)
Regulatory protein:
  • AK6 (human)
Treatment
  • colforsin
  • gefitinib
  • H-89
  • IGF-1
  • imatinib
  • kynurenine
  • LY294002
  • PD184352
  • PGE2
  • phorbol_ester
  • rapamycin
  • wortmannin
view more >
WNK1 (human) EYRRRRHtMDKDSrG T60-p
WNK1 iso2 (human) EYRRRRHTMDKDSRG T60
WNK1 iso4 (human) gap -
WNK1 iso5 (human) EYRRRRHTMDKDSRG T60
WNK1 iso7 (human) EYRRRRHTMDKDSRG T60
WNK1 (mouse) EYRRRRHtMDKDSRG T58-p
WNK1 iso3 (mouse) EYRRRRHTMDKDSRG T58
WNK1 (rat) EYRRRRHTMDKDSRG T58
WNK1 (cow) EYRRRRHTMDKDSRG T60
R66-m1
HtMDKDSrGAAATTT
0 1
WNK1 (human) HtMDKDSrGAAATTT R66-m1
WNK1 iso2 (human) HTMDKDSRGAAATTT R66
WNK1 iso4 (human) gap -
WNK1 iso5 (human) HTMDKDSRGAAATTT R66
WNK1 iso7 (human) HTMDKDSRGAAATTT R66
WNK1 (mouse) HtMDKDSRGAAATTt R64
WNK1 iso3 (mouse) HTMDKDSRGAAATTT R64
WNK1 (rat) HTMDKDSRGAAATTT R64
WNK1 (cow) HTMDKDSRGAAATTT R66
T73
rGAAATTTtTEHRFF
0 1
WNK1 (human) rGAAATTTtTEHRFF T73
WNK1 iso2 (human) RGAAATTTTTEHRFF T73
WNK1 iso4 (human) gap -
WNK1 iso5 (human) RGAAATTTTTEHRFF T73
WNK1 iso7 (human) RGAAATTTTTEHRFF T73
WNK1 (mouse) RGAAATTtPtEHRFF T71-p
WNK1 iso3 (mouse) RGAAATTTPTEHRFF T71
WNK1 (rat) RGAAATTTPTEHRFF T71
WNK1 (cow) SRGAAATTTTEHRFF T72
T74-p
GAAATTTtTEHRFFR
0 1
WNK1 (human) GAAATTTtTEHRFFR T74-p
WNK1 iso2 (human) GAAATTTTTEHRFFR T74
WNK1 iso4 (human) gap -
WNK1 iso5 (human) GAAATTTTTEHRFFR T74
WNK1 iso7 (human) GAAATTTTTEHRFFR T74
WNK1 (mouse) GAAATTtPtEHRFFR P72
WNK1 iso3 (mouse) GAAATTTPTEHRFFR P72
WNK1 (rat) GAAATTTPTEHRFFR P72
WNK1 (cow) RGAAATTTTEHRFFR T73
T75
AAATTTtTEHRFFRR
0 1
WNK1 (human) AAATTTtTEHRFFRR T75
WNK1 iso2 (human) AAATTTTTEHRFFRR T75
WNK1 iso4 (human) gap -
WNK1 iso5 (human) AAATTTTTEHRFFRR T75
WNK1 iso7 (human) AAATTTTTEHRFFRR T75
WNK1 (mouse) AAATTtPtEHRFFRR T73-p
WNK1 iso3 (mouse) AAATTTPTEHRFFRR T73
WNK1 (rat) AAATTTPTEHRFFRR T73
WNK1 (cow) GAAATTTTEHRFFRR T74
S167-p
TSKDRPVsQPsLVGs
Upstream
0 45
Treatment
  • dasatinib
  • sorbitol
WNK1 (human) TSKDRPVsQPsLVGs S167-p
WNK1 iso2 (human) TSKDRPVSQPSLVGS S167
WNK1 iso4 (human) gap -
WNK1 iso5 (human) TSKDRPVSQPSLVGS S167
WNK1 iso7 (human) TSKDRPVSQPSLVGS S167
WNK1 (mouse) TSKDRPVsQPsLVGs S165-p
WNK1 iso3 (mouse) TSKDRPVSQPSLVGS S165
WNK1 (rat) TSKDRPVsQPsLVGs S165-p
WNK1 (cow) AGRDRQAVQPGPAGS V172
S170-p
DRPVsQPsLVGsKEE
0 24
WNK1 (human) DRPVsQPsLVGsKEE S170-p
WNK1 iso2 (human) DRPVSQPSLVGSKEE S170
WNK1 iso4 (human) gap -
WNK1 iso5 (human) DRPVSQPSLVGSKEE S170
WNK1 iso7 (human) DRPVSQPSLVGSKEE S170
WNK1 (mouse) DRPVsQPsLVGsKEE S168-p
WNK1 iso3 (mouse) DRPVSQPSLVGSKEE S168
WNK1 (rat) DRPVsQPsLVGsKEE S168-p
WNK1 (cow) DRQAVQPGPAGSREE G175
S174-p
sQPsLVGsKEEPPPA
0 34
WNK1 (human) sQPsLVGsKEEPPPA S174-p
WNK1 iso2 (human) SQPSLVGSKEEPPPA S174
WNK1 iso4 (human) gap -
WNK1 iso5 (human) SQPSLVGSKEEPPPA S174
WNK1 iso7 (human) SQPSLVGSKEEPPPA S174
WNK1 (mouse) sQPsLVGsKEEPPPs S172-p
WNK1 iso3 (mouse) SQPSLVGSKEEPPPS S172
WNK1 (rat) sQPsLVGsKEEPPPS S172-p
WNK1 (cow) VQPGPAGSREEPPTS S179
A181
sKEEPPPARsGsGGG
0 1
WNK1 (human) sKEEPPPARsGsGGG A181
WNK1 iso2 (human) SKEEPPPARSGSGGG A181
WNK1 iso4 (human) gap -
WNK1 iso5 (human) SKEEPPPARSGSGGG A181
WNK1 iso7 (human) SKEEPPPARSGSGGG A181
WNK1 (mouse) sKEEPPPsRsGsGsG S179-p
WNK1 iso3 (mouse) SKEEPPPSRSGSGSG S179
WNK1 (rat) sKEEPPPSRsGsGsG S179
WNK1 (cow) SREEPPTSRSGSGGG S186
S183-p
EEPPPARsGsGGGsA
0 5
WNK1 (human) EEPPPARsGsGGGsA S183-p
WNK1 iso2 (human) EEPPPARSGSGGGSA S183
WNK1 iso4 (human) gap -
WNK1 iso5 (human) EEPPPARSGSGGGSA S183
WNK1 iso7 (human) EEPPPARSGSGGGSA S183
WNK1 (mouse) EEPPPsRsGsGsGGA S181-p
WNK1 iso3 (mouse) EEPPPSRSGSGSGGA S181
WNK1 (rat) EEPPPSRsGsGsGGA S181-p
WNK1 (cow) EEPPTSRSGSGGGSA S188
S185-p
PPPARsGsGGGsAKE
0 10
WNK1 (human) PPPARsGsGGGsAKE S185-p
WNK1 iso2 (human) PPPARSGSGGGSAKE S185
WNK1 iso4 (human) gap -
WNK1 iso5 (human) PPPARSGSGGGSAKE S185
WNK1 iso7 (human) PPPARSGSGGGSAKE S185
WNK1 (mouse) PPPsRsGsGsGGASA S183-p
WNK1 iso3 (mouse) PPPSRSGSGSGGASA S183
WNK1 (rat) PPPSRsGsGsGGASA S183-p
WNK1 (cow) PPTSRSGSGGGSAKE S190
G187
PARsGsGGGsAKEPQ
0 2
WNK1 (human) PARsGsGGGsAKEPQ G187
WNK1 iso2 (human) PARSGSGGGSAKEPQ G187
WNK1 iso4 (human) gap -
WNK1 iso5 (human) PARSGSGGGSAKEPQ G187
WNK1 iso7 (human) PARSGSGGGSAKEPQ G187
WNK1 (mouse) PsRsGsGsGGASAKE S185-p
WNK1 iso3 (mouse) PSRSGSGSGGASAKE S185
WNK1 (rat) PSRsGsGsGGASAKE S185-p
WNK1 (cow) TSRSGSGGGSAKEPQ G192
S189-p
RsGsGGGsAKEPQEE
0 3
WNK1 (human) RsGsGGGsAKEPQEE S189-p
WNK1 iso2 (human) RSGSGGGSAKEPQEE S189
WNK1 iso4 (human) gap -
WNK1 iso5 (human) RSGSGGGSAKEPQEE S189
WNK1 iso7 (human) RSGSGGGSAKEPQEE S189
WNK1 (mouse) GsGsGGASAKEAQED S189
WNK1 iso3 (mouse) GSGSGGASAKEAQED S189
WNK1 (rat) GsGsGGASAKEPQEE S189
WNK1 (cow) RSGSGGGSAKEPQEE S194
S198-p
KEPQEERsQQQDDIE
0 2
WNK1 (human) KEPQEERsQQQDDIE S198-p
WNK1 iso2 (human) KEPQEERSQQQDDIE S198
WNK1 iso4 (human) gap -
WNK1 iso5 (human) KEPQEERSQQQDDIE S198
WNK1 iso7 (human) KEPQEERSQQQDDIE S198
WNK1 (mouse) KEAQEDRsQQQDDIE S198-p
WNK1 iso3 (mouse) KEAQEDRSQQQDDIE S198
WNK1 (rat) KEPQEERNQQQDDIE N198
WNK1 (cow) KEPQEERSQQQDDIE S203
K375-ub
DLGLATLkRAsFAKs
0 4
WNK1 (human) DLGLATLkRAsFAKs K375-ub
WNK1 iso2 (human) DLGLATLKRASFAKS K375
WNK1 iso4 (human) gap -
WNK1 iso5 (human) DLGLATLKRASFAKS K375
WNK1 iso7 (human) DLGLATLKRASFAKS K375
WNK1 (mouse) DLGLATLKRAsFAKs K375
WNK1 iso3 (mouse) DLGLATLKRASFAKS K375
WNK1 (rat) DLGLATLKRAsFAKs K375
WNK1 (cow) DLGLATLKRASFAKS K380
S378-p
LATLkRAsFAKsVIG
3 7
WNK1 (human) LATLkRAsFAKsVIG S378-p
WNK1 iso2 (human) LATLKRASFAKSVIG S378
WNK1 iso4 (human) gap -
WNK1 iso5 (human) LATLKRASFAKSVIG S378
WNK1 iso7 (human) LATLKRASFAKSVIG S378
WNK1 (mouse) LATLKRAsFAKsVIG S378-p
WNK1 iso3 (mouse) LATLKRASFAKSVIG S378
WNK1 (rat) LATLKRAsFAKsVIG S378-p
WNK1 (cow) LATLKRASFAKSVIG S383
S382-p
kRAsFAKsVIGTPEF
Upstream
Downstream
8 13
Effects on Modified Protein
  • enzymatic activity, induced
Kinase, in vitro:
  • WNK1 (human)
  • WNK2 (human)
  • WNK3 (human)
view more >
Phosphatases, in vitro:
  • PPP1CB (human)
Putative in vivo kinases:
  • WNK1 (human)
Regulatory protein:
  • LRRC8A (human)
  • OSR1 (human)
Treatment
  • hypertonic_buffer
  • hypotonic_buffer
  • low_chloride
  • sorbitol
view more >
WNK1 (human) kRAsFAKsVIGTPEF S382-p
WNK1 iso2 (human) KRASFAKSVIGTPEF S382
WNK1 iso4 (human) gap -
WNK1 iso5 (human) KRASFAKSVIGTPEF S382
WNK1 iso7 (human) KRASFAKSVIGTPEF S382
WNK1 (mouse) KRAsFAKsVIGTPEF S382-p
WNK1 iso3 (mouse) KRASFAKSVIGTPEF S382
WNK1 (rat) KRAsFAKsVIGTPEF S382-p
WNK1 (cow) KRASFAKSVIGTPEF S387
-
gap
0 1
WNK1 (human) gap -
WNK1 iso2 (human) gap -
WNK1 iso4 (human) HCCCCPQkDCINEGV K25-sm
WNK1 iso5 (human) gap -
WNK1 iso7 (human) gap -
WNK1 (mouse) gap -
WNK1 iso3 (mouse) gap -
WNK1 (rat) gap -
WNK1 (cow) gap -
S599-p
QVEQSSAsQTGIKQL
0 9
WNK1 (human) QVEQSSAsQTGIKQL S599-p
WNK1 iso2 (human) QVEQSSASQTGIKQL S599
WNK1 iso4 (human) QVEQSSASQTGIKQL S192
WNK1 iso5 (human) QVEQSSASQTGIKQL S599
WNK1 iso7 (human) QVEQSSASQTGIKQL S599
WNK1 (mouse) NEQQASVSQAGIQQL S600
WNK1 iso3 (mouse) NEQQASVSQAGIQQL S600
WNK1 (rat) NEQQASVSQAGIQPL S600
WNK1 (cow) VEQQPSTAQAGVQQP A605
S679-p
QQTVSYGsQHEQAHS
0 1
WNK1 (human) QQTVSYGsQHEQAHS S679-p
WNK1 iso2 (human) QQTVSYGSQHEQAHS S679
WNK1 iso4 (human) QQTVSYGSQHEQAHS S272
WNK1 iso5 (human) QQTVSYGSQHEQAHS S679
WNK1 iso7 (human) QQTVSYGSQHEQAHS S679
WNK1 (mouse) QQTVSYGSQHEQAHS S680
WNK1 iso3 (mouse) QQTVSYGSQHEQAHS S680
WNK1 (rat) QQTVSYGSQHEQAHS S680
WNK1 (cow) QQTVSYGSQHEQAPS S685
-
gap
0 1
WNK1 (human) gap -
WNK1 iso2 (human) gap -
WNK1 iso4 (human) gap -
WNK1 iso5 (human) ESVLPMHsASQRKHR S780-p
WNK1 iso7 (human) gap -
WNK1 (mouse) gap -
WNK1 iso3 (mouse) gap -
WNK1 (rat) gap -
WNK1 (cow) gap -
-
gap
0 6
WNK1 (human) gap -
WNK1 iso2 (human) gap -
WNK1 iso4 (human) gap -
WNK1 iso5 (human) AISQRRKsTSFLEAQ S847-p
WNK1 iso7 (human) AISQRRKSTSFLEAQ S762
WNK1 (mouse) gap -
WNK1 iso3 (mouse) AISQRRKsTSFLEAQ S763-p
WNK1 (rat) gap -
WNK1 (cow) gap -
-
gap
0 2
WNK1 (human) gap -
WNK1 iso2 (human) gap -
WNK1 iso4 (human) gap -
WNK1 iso5 (human) DSGLGPGsPLSSIsA S1009-p
WNK1 iso7 (human) DSGLGPGSPLSSISA S924
WNK1 (mouse) gap -
WNK1 iso3 (mouse) DSGPSPASPLSSISA S925
WNK1 (rat) gap -
WNK1 (cow) gap -
-
gap
0 1
WNK1 (human) gap -
WNK1 iso2 (human) gap -
WNK1 iso4 (human) gap -
WNK1 iso5 (human) GsPLSSIsAPISTDA S1015-p
WNK1 iso7 (human) GSPLSSISAPISTDA S930
WNK1 (mouse) gap -
WNK1 iso3 (mouse) ASPLSSISAPNSTDA S931
WNK1 (rat) gap -
WNK1 (cow) gap -
-
gap
0 6
WNK1 (human) gap -
WNK1 iso2 (human) gap -
WNK1 iso4 (human) gap -
WNK1 iso5 (human) HPVFVPHsAPAVLTH S1035-p
WNK1 iso7 (human) HPVFVPHSAPAVLTH S950
WNK1 (mouse) gap -
WNK1 iso3 (mouse) HPVFVPHsAPAVLTN S951-p
WNK1 (rat) gap -
WNK1 (cow) gap -
D1069-ca
TTLASSVdSAHSDVA
0 1
WNK1 (human) TTLASSVdSAHSDVA D1069-ca
WNK1 iso2 (human) TTLASSVDSAHSDVA D822
WNK1 iso4 (human) TTLASSVDSAHSDVA D662
WNK1 iso5 (human) TTLASSVDSAHSDVA D1321
WNK1 iso7 (human) TTLASSVDSAHSDVA D1482
WNK1 (mouse) VPLVTSADSAHSDVA D1064
WNK1 iso3 (mouse) VPLVTSADSAHSDVA D1322
WNK1 (rat) VPLVSSVDSAHSDVA D815
WNK1 (cow) AAVVSSIDSAHSDVA D1081
T1098-p
GRHEGRTtKRHyRks
0 1
WNK1 (human) GRHEGRTtKRHyRks T1098-p
WNK1 iso2 (human) GRHEGRTTKRHYRKS T851
WNK1 iso4 (human) GRHEGRTTKRHYRKS T691
WNK1 iso5 (human) GRHEGRTTKRHYRKS T1350
WNK1 iso7 (human) GRHEGRTTKRHYRKS T1511
WNK1 (mouse) GRHEGRTtKRHyRKS T1093-p
WNK1 iso3 (mouse) GRHEGRTTKRHYRKS T1351
WNK1 (rat) GRHEGRTTKRHYRKS T844
WNK1 (cow) GRHEGRTTKRLHRKS T1110
Y1102-p
GRTtKRHyRksVRsR
0 1
WNK1 (human) GRTtKRHyRksVRsR Y1102-p
WNK1 iso2 (human) GRTTKRHYRKSVRSR Y855
WNK1 iso4 (human) GRTTKRHYRKSVRSR Y695
WNK1 iso5 (human) GRTTKRHYRKSVRSR Y1354
WNK1 iso7 (human) GRTTKRHYRKSVRSR Y1515
WNK1 (mouse) GRTtKRHyRKSVRSR Y1097-p
WNK1 iso3 (mouse) GRTTKRHYRKSVRSR Y1355
WNK1 (rat) GRTTKRHYRKSVRSR Y848
WNK1 (cow) GRTTKRLHRKSIRSR H1114
K1104-ac
TtKRHyRksVRsRsR
0 1
WNK1 (human) TtKRHyRksVRsRsR K1104-ac
WNK1 iso2 (human) TTKRHYRKSVRSRSR K857
WNK1 iso4 (human) TTKRHYRKSVRSRSR K697
WNK1 iso5 (human) TTKRHYRKSVRSRSR K1356
WNK1 iso7 (human) TTKRHYRKSVRSRSR K1517
WNK1 (mouse) TtKRHyRKSVRSRSR K1099
WNK1 iso3 (mouse) TTKRHYRKSVRSRSR K1357
WNK1 (rat) TTKRHYRKSVRSRSR K850
WNK1 (cow) TTKRLHRKSIRSRSR K1116
S1105-p
tKRHyRksVRsRsRH
0 14
WNK1 (human) tKRHyRksVRsRsRH S1105-p
WNK1 iso2 (human) TKRHYRKSVRSRSRH S858
WNK1 iso4 (human) TKRHYRKSVRSRSRH S698
WNK1 iso5 (human) TKRHYRKSVRSRSRH S1357
WNK1 iso7 (human) TKRHYRKSVRSRSRH S1518
WNK1 (mouse) tKRHyRKSVRSRSRH S1100
WNK1 iso3 (mouse) TKRHYRKSVRSRSRH S1358
WNK1 (rat) TKRHYRKSVRSRSRH S851
WNK1 (cow) TKRLHRKSIRSRSRH S1117
S1108-p
HyRksVRsRsRHEKt
0 8
WNK1 (human) HyRksVRsRsRHEKt S1108-p
WNK1 iso2 (human) HYRKSVRSRSRHEKT S861
WNK1 iso4 (human) HYRKSVRSRSRHEKT S701
WNK1 iso5 (human) HYRKSVRSRSRHEKT S1360
WNK1 iso7 (human) HYRKSVRSRSRHEKT S1521
WNK1 (mouse) HyRKSVRSRSRHEKT S1103
WNK1 iso3 (mouse) HYRKSVRSRSRHEKT S1361
WNK1 (rat) HYRKSVRSRSRHEKT S854
WNK1 (cow) LHRKSIRSRSRHEKP S1120
S1110-p
RksVRsRsRHEKtsR
0 7
WNK1 (human) RksVRsRsRHEKtsR S1110-p
WNK1 iso2 (human) RKSVRSRSRHEKTSR S863
WNK1 iso4 (human) RKSVRSRSRHEKTSR S703
WNK1 iso5 (human) RKSVRSRSRHEKTSR S1362
WNK1 iso7 (human) RKSVRSRSRHEKTSR S1523
WNK1 (mouse) RKSVRSRSRHEKTSR S1105
WNK1 iso3 (mouse) RKSVRSRSRHEKTSR S1363
WNK1 (rat) RKSVRSRSRHEKTSR S856
WNK1 (cow) RKSIRSRSRHEKPSR S1122
T1115-p
sRsRHEKtsRPkLRI
0 1
WNK1 (human) sRsRHEKtsRPkLRI T1115-p
WNK1 iso2 (human) SRSRHEKTSRPKLRI T868
WNK1 iso4 (human) SRSRHEKTSRPKLRI T708
WNK1 iso5 (human) SRSRHEKTSRPKLRI T1367
WNK1 iso7 (human) SRSRHEKTSRPKLRI T1528
WNK1 (mouse) SRSRHEKTSRPKLRI T1110
WNK1 iso3 (mouse) SRSRHEKTSRPKLRI T1368
WNK1 (rat) SRSRHEKTSRPkLRI T861
WNK1 (cow) SRSRHEKPSRPKLRI P1127
S1116-p
RsRHEKtsRPkLRIL
0 1
WNK1 (human) RsRHEKtsRPkLRIL S1116-p
WNK1 iso2 (human) RSRHEKTSRPKLRIL S869
WNK1 iso4 (human) RSRHEKTSRPKLRIL S709
WNK1 iso5 (human) RSRHEKTSRPKLRIL S1368
WNK1 iso7 (human) RSRHEKTSRPKLRIL S1529
WNK1 (mouse) RSRHEKTSRPKLRIL S1111
WNK1 iso3 (mouse) RSRHEKTSRPKLRIL S1369
WNK1 (rat) RSRHEKTSRPkLRIL S862
WNK1 (cow) RSRHEKPSRPKLRIL S1128
K1119-ac
HEKtsRPkLRILNVS
0 2
WNK1 (human) HEKtsRPkLRILNVS K1119-ac
WNK1 iso2 (human) HEKTSRPKLRILNVS K872
WNK1 iso4 (human) HEKTSRPKLRILNVS K712
WNK1 iso5 (human) HEKTSRPKLRILNVS K1371
WNK1 iso7 (human) HEKTSRPKLRILNVS K1532
WNK1 (mouse) HEKTSRPKLRILNVS K1114
WNK1 iso3 (mouse) HEKTSRPKLRILNVS K1372
WNK1 (rat) HEKTSRPkLRILNVS K865-ac
WNK1 (cow) HEKPSRPKLRILNVS K1131
K1128-ac
RILNVSNkGDRVVEC
0 1
WNK1 (human) RILNVSNkGDRVVEC K1128-ac
WNK1 iso2 (human) RILNVSNKGDRVVEC K881
WNK1 iso4 (human) RILNVSNKGDRVVEC K721
WNK1 iso5 (human) RILNVSNKGDRVVEC K1380
WNK1 iso7 (human) RILNVSNKGDRVVEC K1541
WNK1 (mouse) RILNVSNKGDRVVEC K1123
WNK1 iso3 (mouse) RILNVSNKGDRVVEC K1381
WNK1 (rat) RILNVSNKGDRVVEC K874
WNK1 (cow) RILNVSNKGDRVVEC K1140
S1197
EMLSEDVSVEPEGDQ
0 1
WNK1 (human) EMLSEDVSVEPEGDQ S1197
WNK1 iso2 (human) EMLSEDVSVEPEGDQ S950
WNK1 iso4 (human) EMLSEDVSVEPEGDQ S790
WNK1 iso5 (human) EMLSEDVSVEPEGDQ S1449
WNK1 iso7 (human) EMLSEDVSVEPEGDQ S1610
WNK1 (mouse) EMLSEDVsVEPEGDQ S1192-p
WNK1 iso3 (mouse) EMLSEDVSVEPEGDQ S1450
WNK1 (rat) EMLSEDVSVEPEGDQ S943
WNK1 (cow) EMLSEDVSVEPEGDQ S1209
S1208
EGDQGLESLQGKDDy
0 1
WNK1 (human) EGDQGLESLQGKDDy S1208
WNK1 iso2 (human) EGDQGLESLQGKDDY S961
WNK1 iso4 (human) EGDQGLESLQGKDDY S801
WNK1 iso5 (human) EGDQGLESLQGKDDY S1460
WNK1 iso7 (human) EGDQGLESLQGKDDY S1621
WNK1 (mouse) EGDQGLEsLQGKDDY S1203-p
WNK1 iso3 (mouse) EGDQGLESLQGKDDY S1461
WNK1 (rat) EGDQGLESLQGKDDY S954
WNK1 (cow) EGDQSLESLHGKDDY S1220
Y1215-p
SLQGKDDyGFSGsQK
0 12
WNK1 (human) SLQGKDDyGFSGsQK Y1215-p
WNK1 iso2 (human) SLQGKDDYGFSGSQK Y968
WNK1 iso4 (human) SLQGKDDYGFSGSQK Y808
WNK1 iso5 (human) SLQGKDDYGFSGSQK Y1467
WNK1 iso7 (human) SLQGKDDYGFSGSQK Y1628
WNK1 (mouse) sLQGKDDYGFPGSQK Y1210
WNK1 iso3 (mouse) SLQGKDDYGFPGSQK Y1468
WNK1 (rat) SLQGKDDYGFPGSQK Y961
WNK1 (cow) SLHGKDDYGFSGTQK Y1227
S1220-p
DDyGFSGsQKLEGEF
0 2
WNK1 (human) DDyGFSGsQKLEGEF S1220-p
WNK1 iso2 (human) DDYGFSGSQKLEGEF S973
WNK1 iso4 (human) DDYGFSGSQKLEGEF S813
WNK1 iso5 (human) DDYGFSGSQKLEGEF S1472
WNK1 iso7 (human) DDYGFSGSQKLEGEF S1633
WNK1 (mouse) DDYGFPGSQKLEGEF S1215
WNK1 iso3 (mouse) DDYGFPGSQKLEGEF S1473
WNK1 (rat) DDYGFPGSQKLEGEF S966
WNK1 (cow) DDYGFSGTQKLEGEF T1232
S1235
KQPIPASSMPQQIGI
0 1
WNK1 (human) KQPIPASSMPQQIGI S1235
WNK1 iso2 (human) KQPIPASSMPQQIGI S988
WNK1 iso4 (human) KQPIPASSMPQQIGI S828
WNK1 iso5 (human) KQPIPASSMPQQIGI S1487
WNK1 iso7 (human) KQPIPASSMPQQIGI S1648
WNK1 (mouse) KQPIAVSsMPQQIGV S1230-gl
WNK1 iso3 (mouse) KQPIAVSSMPQQIGV S1488
WNK1 (rat) KQPIAVSSMPQQIGV S981
WNK1 (cow) KQPIPASSLPQQIAG S1247
S1253-p
SLTQVVHsAGRRFIV
0 1
WNK1 (human) SLTQVVHsAGRRFIV S1253-p
WNK1 iso2 (human) SLTQVVHSAGRRFIV S1006
WNK1 iso4 (human) SLTQVVHSAGRRFIV S846
WNK1 iso5 (human) SLTQVVHSAGRRFIV S1505
WNK1 iso7 (human) SLTQVVHSAGRRFIV S1666
WNK1 (mouse) SLTQVVHSAGRRFIV S1248
WNK1 iso3 (mouse) SLTQVVHSAGRRFIV S1506
WNK1 (rat) SLTQVVHSAGRRFIV S999
WNK1 (cow) SLTQVVHSAGRRFIV S1266
S1261-p
AGRRFIVsPVPESRL
Upstream
Downstream
1 23
Effects on Modified Protein
  • enzymatic activity, induced
  • molecular association, regulation
Regulatory protein:
  • OSR1 (human)
Treatment
  • low_chloride
  • sorbitol
WNK1 (human) AGRRFIVsPVPESRL S1261-p
WNK1 iso2 (human) AGRRFIVSPVPESRL S1014
WNK1 iso4 (human) AGRRFIVSPVPESRL S854
WNK1 iso5 (human) AGRRFIVSPVPESRL S1513
WNK1 iso7 (human) AGRRFIVSPVPESRL S1674
WNK1 (mouse) AGRRFIVsPVPEsRL S1256-p
WNK1 iso3 (mouse) AGRRFIVSPVPESRL S1514
WNK1 (rat) AGRRFIVSPVPESRL S1007
WNK1 (cow) AGRRFIVSPVPESRL S1274
S1266
IVsPVPESRLRESKV
0 2
WNK1 (human) IVsPVPESRLRESKV S1266
WNK1 iso2 (human) IVSPVPESRLRESKV S1019
WNK1 iso4 (human) IVSPVPESRLRESKV S859
WNK1 iso5 (human) IVSPVPESRLRESKV S1518
WNK1 iso7 (human) IVSPVPESRLRESKV S1679
WNK1 (mouse) IVsPVPEsRLRESKV S1261-p
WNK1 iso3 (mouse) IVSPVPESRLRESKV S1519
WNK1 (rat) IVSPVPESRLRESKI S1012
WNK1 (cow) IVSPVPESRLRESKL S1279
S1285-p
ITDTVAAsTAQSPGM
0 1
WNK1 (human) ITDTVAAsTAQSPGM S1285-p
WNK1 iso2 (human) ITDTVAASTAQSPGM S1038
WNK1 iso4 (human) ITDTVAASTAQSPGM S878
WNK1 iso5 (human) ITDTVAASTAQSPGM S1537
WNK1 iso7 (human) ITDTVAASTAQSPGM S1698
WNK1 (mouse) ISDPVVASTSQAPGM S1280
WNK1 iso3 (mouse) ISDPVVASTSQAPGM S1538
WNK1 (rat) IPDPVAASTSQGPGM S1031
WNK1 (cow) ISDTVAASTSAGPGM S1297
S1295-p
QSPGMNLsHsASsLS
0 1
WNK1 (human) QSPGMNLsHsASsLS S1295-p
WNK1 iso2 (human) QSPGMNLSHSASSLS S1048
WNK1 iso4 (human) QSPGMNLSHSASSLS S888
WNK1 iso5 (human) QSPGMNLSHSASSLS S1547
WNK1 iso7 (human) QSPGMNLSHSASSLS S1708
WNK1 (mouse) QAPGMNLSHsAssLS S1290
WNK1 iso3 (mouse) QAPGMNLSHSASSLS S1548
WNK1 (rat) QGPGMNLSHSASSLS S1041
WNK1 (cow) AGPGMNLSHSASSLS S1307
S1297-p
PGMNLsHsASsLSLQ
Upstream
0 3
Treatment
  • EGF
WNK1 (human) PGMNLsHsASsLSLQ S1297-p
WNK1 iso2 (human) PGMNLSHSASSLSLQ S1050
WNK1 iso4 (human) PGMNLSHSASSLSLQ S890
WNK1 iso5 (human) PGMNLSHSASSLSLQ S1549
WNK1 iso7 (human) PGMNLSHSASSLSLQ S1710
WNK1 (mouse) PGMNLSHsAssLSLQ S1292-p
WNK1 iso3 (mouse) PGMNLSHSASSLSLQ S1550
WNK1 (rat) PGMNLSHSASSLSLQ S1043
WNK1 (cow) PGMNLSHSASSLSLQ S1309
S1299
MNLsHsASsLSLQQA
0 2
WNK1 (human) MNLsHsASsLSLQQA S1299
WNK1 iso2 (human) MNLSHSASSLSLQQA S1052
WNK1 iso4 (human) MNLSHSASSLSLQQA S892
WNK1 iso5 (human) MNLSHSASSLSLQQA S1551
WNK1 iso7 (human) MNLSHSASSLSLQQA S1712
WNK1 (mouse) MNLSHsAssLSLQQA S1294-p
WNK1 iso3 (mouse) MNLSHSASSLSLQQA S1552
WNK1 (rat) MNLSHSASSLSLQQA S1045
WNK1 (cow) MNLSHSASSLSLQQA S1311
S1300-p
NLsHsASsLSLQQAF
0 4
WNK1 (human) NLsHsASsLSLQQAF S1300-p
WNK1 iso2 (human) NLSHSASSLSLQQAF S1053
WNK1 iso4 (human) NLSHSASSLSLQQAF S893
WNK1 iso5 (human) NLSHSASSLSLQQAF S1552
WNK1 iso7 (human) NLSHSASSLSLQQAF S1713
WNK1 (mouse) NLSHsAssLSLQQAF S1295-p
WNK1 iso3 (mouse) NLSHSASSLSLQQAF S1553
WNK1 (rat) NLSHSASSLSLQQAF S1046
WNK1 (cow) NLSHSASSLSLQQAF S1312
T1316
ELRRAQMTEGPNTAP
0 1
WNK1 (human) ELRRAQMTEGPNTAP T1316
WNK1 iso2 (human) ELRRAQMTEGPNTAP T1069
WNK1 iso4 (human) ELRRAQMTEGPNTAP T909
WNK1 iso5 (human) ELRRAQMTEGPNTAP T1568
WNK1 iso7 (human) ELRRAQMTEGPNTAP T1729
WNK1 (mouse) ELKHGQMtEGPNtAP T1311-p
WNK1 iso3 (mouse) ELKHGQMTEGPNTAP T1569
WNK1 (rat) ELKHGQMTEGPNTAP T1062
WNK1 (cow) ELRHARMAEGPSTAP A1328
T1321
QMTEGPNTAPPNFSH