Y113
|
IRGWKLFYNYALVIF
|
|
|
0
|
1
|
|
|
IGF1R (human)
|
IRGWKLFyNyALVIF
|
Y113-p
|
IGF1R (mouse)
|
IRGWKLFYNYALVIF
|
Y113
|
IGF1R (rat)
|
IRGWKLFYNYALVIF
|
Y113
|
IGF1R (pig)
|
IRGWKLFYNYALVIF
|
Y113
|
|
Y115
|
GWKLFYNYALVIFEM
|
|
|
0
|
1
|
|
|
IGF1R (human)
|
GWKLFyNyALVIFEM
|
Y115-p
|
IGF1R (mouse)
|
GWKLFYNYALVIFEM
|
Y115
|
IGF1R (rat)
|
GWKLFYNYALVIFEM
|
Y115
|
IGF1R (pig)
|
GWKLFYNYALVIFEM
|
Y115
|
|
T123
|
ALVIFEMTNLKDIGL
|
|
|
0
|
1
|
|
|
IGF1R (human)
|
ALVIFEMtNLKDIGL
|
T123-p
|
IGF1R (mouse)
|
ALVIFEMTNLKDIGL
|
T123
|
IGF1R (rat)
|
ALVIFEMTNLKDIGL
|
T123
|
IGF1R (pig)
|
ALVIFEMTNLKDIGL
|
T123
|
|
Y131
|
NLKDIGLYNLRNITR
|
|
|
0
|
1
|
|
|
IGF1R (human)
|
NLKDIGLyNLRNITR
|
Y131-p
|
IGF1R (mouse)
|
NLKDIGLYNLRNITR
|
Y131
|
IGF1R (rat)
|
NLKDIGLYNLRNITR
|
Y131
|
IGF1R (pig)
|
NLKDIGLYNLRNITR
|
Y131
|
|
D245
|
SCSAPDNDTACVACR
|
|
|
0
|
1
|
|
|
IGF1R (human)
|
SCSAPDNDTACVACR
|
D245
|
IGF1R (mouse)
|
SCHTPDDnTTCVACR
|
N245-ng
|
IGF1R (rat)
|
SCHTPDDNTTCVACR
|
N245
|
IGF1R (pig)
|
SCSAPDNDTACVACR
|
D245
|
|
N314
|
CPSGFIRNGSQSMYC
|
|
|
0
|
1
|
|
|
IGF1R (human)
|
CPSGFIRNGSQSMYC
|
N314
|
IGF1R (mouse)
|
CPSGFIRnSTQSMYC
|
N314-ng
|
IGF1R (rat)
|
CPSGFIRNSTQSMYC
|
N314
|
IGF1R (pig)
|
CPSGFIRNGSQSMYC
|
N314
|
|
R471
|
EVTGTKGRQSKGDIN
|
|
|
0
|
1
|
|
|
IGF1R (human)
|
EVTGTKGrQSKGDIN
|
R471-m1
|
IGF1R (mouse)
|
EVTGTKGRQSKGDIN
|
R472
|
IGF1R (rat)
|
EVTGTKGRQSKGDIN
|
R472
|
IGF1R (pig)
|
EVTGTKGRQSKGDIN
|
R471
|
|
R480
|
SKGDINTRNNGERAS
|
|
|
0
|
1
|
|
|
IGF1R (human)
|
SKGDINTrNNGERAS
|
R480-m1
|
IGF1R (mouse)
|
SKGDINTRNNGERAS
|
R481
|
IGF1R (rat)
|
SKGDINTRNNGERAS
|
R481
|
IGF1R (pig)
|
SKGDINTRNNGERAS
|
R480
|
|
N607
|
EILYIRTNASVPSIP
|
|
|
0
|
1
|
|
|
IGF1R (human)
|
EILYIRTNASVPSIP
|
N607
|
IGF1R (mouse)
|
EILYIRTnASVPSIP
|
N608-ng
|
IGF1R (rat)
|
EILYIRTNASVPSIP
|
N608
|
IGF1R (pig)
|
EILYIRTNASVPSIP
|
N607
|
|
N622
|
LDVLSASNSSSQLIV
|
|
|
0
|
1
|
|
|
IGF1R (human)
|
LDVLSASNssSQLIV
|
N622
|
IGF1R (mouse)
|
LDVLSASnSSSQLIV
|
N623-ng
|
IGF1R (rat)
|
LDVLSASNSSSQLIV
|
N623
|
IGF1R (pig)
|
LDVLSASNSSSQLIV
|
N622
|
|
S623
|
DVLSASNSSSQLIVK
|
|
|
0
|
1
|
|
|
IGF1R (human)
|
DVLSASNssSQLIVK
|
S623-p
|
IGF1R (mouse)
|
DVLSASnSSSQLIVK
|
S624
|
IGF1R (rat)
|
DVLSASNSSSQLIVK
|
S624
|
IGF1R (pig)
|
DVLSASNSSSQLIVK
|
S623
|
|
S624
|
VLSASNSSSQLIVKW
|
|
|
0
|
1
|
|
|
IGF1R (human)
|
VLSASNssSQLIVKW
|
S624-p
|
IGF1R (mouse)
|
VLSASnSSSQLIVKW
|
S625
|
IGF1R (rat)
|
VLSASNSSSQLIVKW
|
S625
|
IGF1R (pig)
|
VLSASNSSSQLIVKW
|
S624
|
|
N640
|
PPSLPNGNLSYYIVR
|
|
|
0
|
1
|
|
|
IGF1R (human)
|
PPSLPNGNLSYYIVR
|
N640
|
IGF1R (mouse)
|
PPTLPNGnLSYYIVR
|
N641-ng
|
IGF1R (rat)
|
PPTLPNGNLSYYIVR
|
N641
|
IGF1R (pig)
|
PPSLPNGNLSYYIVR
|
N640
|
|
K672
|
KDKIPIRKYADGTID
|
|
|
0
|
1
|
|
|
IGF1R (human)
|
KDKIPIRkYADGTID
|
K672-ub
|
IGF1R (mouse)
|
KDKIPIRKYADGTID
|
K673
|
IGF1R (rat)
|
KDKIPIRKYADGTID
|
K673
|
IGF1R (pig)
|
KDKIPIRKYADGTID
|
K672
|
|
N747
|
REVMQVANTTMSSRS
|
|
|
0
|
1
|
|
|
IGF1R (human)
|
RDVMQVANTTMSSRS
|
N747
|
IGF1R (mouse)
|
RDVMQVAnTTMSSRS
|
N748-ng
|
IGF1R (rat)
|
RDVLQVANTTMSSRS
|
N748
|
IGF1R (pig)
|
REVMQVANTTMSSRS
|
N747
|
|
N756
|
TMSSRSRNTTVVDTY
|
|
|
0
|
1
|
|
|
IGF1R (human)
|
TMSSRSRNTTAADTY
|
N756
|
IGF1R (mouse)
|
TMSSRSRnTTVADTY
|
N757-ng
|
IGF1R (rat)
|
TMSSRSRNTTVADTY
|
N757
|
IGF1R (pig)
|
TMSSRSRNTTVVDTY
|
N756
|
|
N764
|
TTVVDTYNVTDPEEL
|
|
|
0
|
1
|
|
|
IGF1R (human)
|
TTAADTYNITDPEEL
|
N764
|
IGF1R (mouse)
|
TTVADTYnITDPEEF
|
N765-ng
|
IGF1R (rat)
|
TTVADTYNITDPEEF
|
N765
|
IGF1R (pig)
|
TTVVDTYNVTDPEEL
|
N764
|
|
N900
|
LNRLNPGNYTARIQA
|
|
|
0
|
1
|
|
|
IGF1R (human)
|
LNRLNPGNYTARIQA
|
N900
|
IGF1R (mouse)
|
LNRLNPGnYTARIQA
|
N901-ng
|
IGF1R (rat)
|
LNRLNPGNYTARIQA
|
N901
|
IGF1R (pig)
|
LNRLNPGNYTARIQA
|
N900
|
|
N913
|
QATSLSGNGSWTEPV
|
|
|
0
|
1
|
|
|
IGF1R (human)
|
QATSLSGNGSWTDPV
|
N913
|
IGF1R (mouse)
|
QATSLSGnGSWTDPV
|
N914-ng
|
IGF1R (rat)
|
QATSLSGNGSWTDPV
|
N914
|
IGF1R (pig)
|
QATSLSGNGSWTEPV
|
N913
|
|
Y973
|
RLGNGVLYASVNPEY
|
|
|
2
|
1
|
|
|
IGF1R (human)
|
RLGNGVLyAsVNPEy
|
Y973-p
|
IGF1R (mouse)
|
RLGNGVLyASVNPEy
|
Y974-p
|
IGF1R (rat)
|
RLGNGVLYASVNPEY
|
Y974
|
IGF1R (pig)
|
RLGNGVLYASVNPEY
|
Y973
|
|
S975
|
GNGVLYASVNPEYFS
|
|
|
0
|
1
|
|
|
IGF1R (human)
|
GNGVLyAsVNPEyFs
|
S975-p
|
IGF1R (mouse)
|
GNGVLyASVNPEyFS
|
S976
|
IGF1R (rat)
|
GNGVLYASVNPEYFS
|
S976
|
IGF1R (pig)
|
GNGVLYASVNPEYFS
|
S975
|
|
Y980
|
YASVNPEYFSAADVY
|
|
|
8
|
5
|
|
|
|
IGF1R (human)
|
yAsVNPEyFsAADVY
|
Y980-p
|
IGF1R (mouse)
|
yASVNPEyFSAADVY
|
Y981-p
|
IGF1R (rat)
|
YASVNPEYFSAADVY
|
Y981
|
IGF1R (pig)
|
YASVNPEYFSAADVY
|
Y980
|
|
S982
|
SVNPEYFSAADVYVP
|
|
|
1
|
0
|
|
|
IGF1R (human)
|
sVNPEyFsAADVYVP
|
S982-p
|
IGF1R (mouse)
|
SVNPEyFSAADVYVP
|
S983
|
IGF1R (rat)
|
SVNPEYFSAADVYVP
|
S983
|
IGF1R (pig)
|
SVNPEYFSAADVYVP
|
S982
|
|
S1009
|
SRELGQGSFGMVYEG
|
|
|
0
|
1
|
|
|
IGF1R (human)
|
SRELGQGsFGMVyEG
|
S1009-p
|
IGF1R (mouse)
|
NRELGQGSFGMVYEG
|
S1010
|
IGF1R (rat)
|
NRELGQGSFGMVYEG
|
S1010
|
IGF1R (pig)
|
SRELGQGSFGMVYEG
|
S1009
|
|
Y1014
|
QGSFGMVYEGVAKGV
|
|
|
0
|
5
|
|
|
IGF1R (human)
|
QGsFGMVyEGVAKGV
|
Y1014-p
|
IGF1R (mouse)
|
QGSFGMVYEGVAKGV
|
Y1015
|
IGF1R (rat)
|
QGSFGMVYEGVAKGV
|
Y1015
|
IGF1R (pig)
|
QGSFGMVYEGVAKGV
|
Y1014
|
|
K1023
|
GVAKGVVKDEPETRV
|
|
|
0
|
1
|
|
|
IGF1R (human)
|
GVAKGVVKDEPETRV
|
K1023
|
IGF1R (mouse)
|
GVAKGVVkDEPETRV
|
K1024-ac
|
IGF1R (rat)
|
GVAKGVVKDEPETRV
|
K1024
|
IGF1R (pig)
|
GVAKGVVKDEPETRV
|
K1023
|
|
K1033
|
PETRVAIKTVNEAAS
|
|
|
0
|
11
|
|
|
IGF1R (human)
|
PETRVAIkTVNEAAS
|
K1033-ub
|
IGF1R (mouse)
|
PETRVAIkTVNEAAS
|
K1034-ub
|
IGF1R (rat)
|
PETRVAIKTVNEAAS
|
K1034
|
IGF1R (pig)
|
PETRVAIKTVNEAAS
|
K1033
|
|
K1055
|
LNEASVMKEFNCHHV
|
|
|
2
|
0
|
|
|
IGF1R (human)
|
LNEASVMkEFNCHHV
|
K1055-sm
|
IGF1R (mouse)
|
LNEASVMKEFNCHHV
|
K1056
|
IGF1R (rat)
|
LNEASVMKEFNCHHV
|
K1056
|
IGF1R (pig)
|
LNEASVMKEFNCHHV
|
K1055
|
|
K1130
|
MAYLNANKFVHRDLA
|
|
|
2
|
0
|
|
|
IGF1R (human)
|
MAYLNANkFVHRDLA
|
K1130-sm
|
IGF1R (mouse)
|
MAYLNANKFVHRDLA
|
K1132
|
IGF1R (rat)
|
MAYLNANKFVHRDLA
|
K1131
|
IGF1R (pig)
|
MAYLNANKFVHRDLA
|
K1130
|
|
K1150
|
VAEDFTVKIGDFGMT
|
|
|
1
|
0
|
|
|
IGF1R (human)
|
VAEDFTVkIGDFGMT
|
K1150-sm
|
IGF1R (mouse)
|
VAEDFTVKIGDFGMT
|
K1152
|
IGF1R (rat)
|
VAEDFTVKIGDFGMT
|
K1151
|
IGF1R (pig)
|
VAEDFTVKIGDFGMT
|
K1150
|
|
Y1161-p
|
FGMTRDIyETDYYRK
|
Upstream
|
Downstream
|
24
|
483
|
|
|
|
Effects on Modified Protein
|
|
Treatment
- AG1478
- angiotensin
- IGF-1
- losartan
- PP1
|
|
|
T1163
|
MTRDIyETDYYRKGG
|
|
|
0
|
56
|
|
|
IGF1R (human)
|
MTRDIyEtDyyRKGG
|
T1163-p
|
IGF1R (mouse)
|
MTRDIyEtDyyRKGG
|
T1165-p
|
IGF1R (rat)
|
MTRDIyETDyyRKGG
|
T1164
|
IGF1R (pig)
|
MTRDIyETDYYRKGG
|
T1163
|
|
Y1165
|
RDIyETDYYRKGGKG
|
|
|
23
|
742
|
|
|
|
IGF1R (human)
|
RDIyEtDyyRKGGkG
|
Y1165-p
|
IGF1R (mouse)
|
RDIyEtDyyRKGGkG
|
Y1167-p
|
IGF1R (rat)
|
RDIyETDyyRKGGKG
|
Y1166-p
|
IGF1R (pig)
|
RDIyETDYYRKGGKG
|
Y1165
|
|
Y1166
|
DIyETDYYRKGGKGL
|
|
|
18
|
121
|
|
|
|
IGF1R (human)
|
DIyEtDyyRKGGkGL
|
Y1166-p
|
IGF1R (mouse)
|
DIyEtDyyRKGGkGL
|
Y1168-p
|
IGF1R (rat)
|
DIyETDyyRKGGKGL
|
Y1167-p
|
IGF1R (pig)
|
DIyETDYYRKGGKGL
|
Y1166
|
|
K1171
|
DYYRKGGKGLLPVRW
|
|
|
0
|
5
|
|
|
IGF1R (human)
|
DyyRKGGkGLLPVRW
|
K1171-ub
|
IGF1R (mouse)
|
DyyRKGGkGLLPVRW
|
K1173-ub
|
IGF1R (rat)
|
DyyRKGGKGLLPVRW
|
K1172
|
IGF1R (pig)
|
DYYRKGGKGLLPVRW
|
K1171
|
|
S1193
|
DGVFTTHSDVWSFGV
|
|
|
0
|
1
|
|
|
IGF1R (human)
|
DGVFTTYsDVWSFGV
|
S1193-p
|
IGF1R (mouse)
|
DGVFTTHSDVWSFGV
|
S1195
|
IGF1R (rat)
|
DGVFTTHSDVWSFGV
|
S1194
|
IGF1R (pig)
|
DGVFTTHSDVWSFGV
|
S1193
|
|
S1278
|
EPGFREVSFYYSEEN
|
|
|
1
|
1
|
|
|
IGF1R (human)
|
EPGFREVsFyySEEN
|
S1278-p
|
IGF1R (mouse)
|
EPSFQEVSFyySEEN
|
S1280
|
IGF1R (rat)
|
EPSFQEVSFYYSEEN
|
S1279
|
IGF1R (pig)
|
EPGFREVSFYYSEEN
|
S1278
|
|
Y1280
|
GFREVSFYYSEENKP
|
|
|
5
|
0
|
|
|
IGF1R (human)
|
GFREVsFyySEENKL
|
Y1280-p
|
IGF1R (mouse)
|
SFQEVSFyySEENKP
|
Y1282-p
|
IGF1R (rat)
|
SFQEVSFYYSEENKP
|
Y1281
|
IGF1R (pig)
|
GFREVSFYYSEENKP
|
Y1280
|
|
Y1281
|
FREVSFYYSEENKPP
|
|
|
5
|
0
|
|
|
IGF1R (human)
|
FREVsFyySEENKLP
|
Y1281-p
|
IGF1R (mouse)
|
FQEVSFyySEENKPP
|
Y1283-p
|
IGF1R (rat)
|
FQEVSFYYSEENKPP
|
Y1282
|
IGF1R (pig)
|
FREVSFYYSEENKPP
|
Y1281
|
|
S1310
|
VPLDPSASSSSLPLP
|
|
|
2
|
0
|
|
|
IGF1R (human)
|
VPLDPSAssssLPLP
|
S1310-p
|
IGF1R (mouse)
|
VPLDPSASSASLPLP
|
S1316
|
IGF1R (rat)
|
VPLDPSASSASLPLP
|
S1315
|
IGF1R (pig)
|
VPLDPSASSSSLPLP
|
S1310
|
|
S1311
|
PLDPSASSSSLPLPD
|
|
|
2
|
0
|
|
|
IGF1R (human)
|
PLDPSAssssLPLPD
|
S1311-p
|
IGF1R (mouse)
|
PLDPSASSASLPLPE
|
S1317
|
IGF1R (rat)
|
PLDPSASSASLPLPE
|
S1316
|
IGF1R (pig)
|
PLDPSASSSSLPLPD
|
S1311
|
|
S1312
|
LDPSASSSSLPLPDR
|
|
|
2
|
0
|
|
|
IGF1R (human)
|
LDPSAssssLPLPDR
|
S1312-p
|
IGF1R (mouse)
|
LDPSASSASLPLPER
|
A1318
|
IGF1R (rat)
|
LDPSASSASLPLPER
|
A1317
|
IGF1R (pig)
|
LDPSASSSSLPLPDR
|
S1312
|
|
S1313
|
DPSASSSSLPLPDRH
|
|
|
2
|
0
|
|
|
IGF1R (human)
|
DPSAssssLPLPDRH
|
S1313-p
|
IGF1R (mouse)
|
DPSASSASLPLPERH
|
S1319
|
IGF1R (rat)
|
DPSASSASLPLPERH
|
S1318
|
IGF1R (pig)
|
DPSASSSSLPLPDRH
|
S1313
|
|
S1321
|
LPLPDRHSGHKAENG
|
|
|
1
|
0
|
|
|
IGF1R (human)
|
LPLPDRHsGHKAENG
|
S1321-p
|
IGF1R (mouse)
|
LPLPERHSGHKAENG
|
S1327
|
IGF1R (rat)
|
LPLPERHSGHKAENG
|
S1326
|
IGF1R (pig)
|
LPLPDRHSGHKAENG
|
S1321
|
|
S1339
|
GVLVLRASFDERQPY
|
|
|
0
|
9
|
|
|
IGF1R (human)
|
GVLVLRAsFDERQPy
|
S1339-p
|
IGF1R (mouse)
|
GVLVLRAsFDERQPy
|
S1345-p
|
IGF1R (rat)
|
GVLVLRASFDERQPY
|
S1342
|
IGF1R (pig)
|
GVLVLRASFDERQPY
|
S1339
|
|
Y1346
|
SFDERQPYAHMNGGR
|
|
|
3
|
34
|
|
|
|
IGF1R (human)
|
sFDERQPyAHMNGGR
|
Y1346-p
|
IGF1R (mouse)
|
sFDERQPyAHMNGGR
|
Y1352-p
|
IGF1R (rat)
|
SFDERQPYAHMNGGR
|
Y1349
|
IGF1R (pig)
|
SFDERQPYAHMNGGR
|
Y1346
|
|
K1354
|
AHMNGGRKNERALPL
|
|
|
0
|
1
|
|
|
IGF1R (human)
|
AHMNGGRkNERALPL
|
K1354-m1
|
IGF1R (mouse)
|
AHMNGGRANERALPL
|
A1360
|
IGF1R (rat)
|
AHMNGGRANERALPL
|
A1357
|
IGF1R (pig)
|
AHMNGGRKNERALPL
|
K1354
|
|
T1366
|
LPLPQSSTC______
|
|
|
0
|
13
|
|
|
IGF1R (human)
|
LPLPQSStC______
|
T1366-p
|
IGF1R (mouse)
|
LPLPQSStC______
|
T1372-p
|
IGF1R (rat)
|
LPLPQSSTC______
|
T1369
|
IGF1R (pig)
|
LPLPQSSTC______
|
T1366
|
|