Other Species / Isoforms
  PAK6 (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

 HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
T69-p
VQLQPMKtVVRGSAM
Upstream
0 1
Treatment
  • MLN8054
PAK6 (human) VQLQPMKtVVRGSAM T69-p
PAK6 (mouse) VQLQPMKTVVRGSSV T69
PAK6 (rat) VQLQPMKTVVRGssV T69
S74
MKtVVRGSAMPVDGy
0 1
PAK6 (human) MKtVVRGSAMPVDGy S74
PAK6 (mouse) MKTVVRGSSVPTEGY S74
PAK6 (rat) MKTVVRGssVPtEGY S74-p
A75
KtVVRGSAMPVDGyI
0 1
PAK6 (human) KtVVRGSAMPVDGyI A75
PAK6 (mouse) KTVVRGSSVPTEGYI S75
PAK6 (rat) KTVVRGssVPtEGYI S75-p
V78
VRGSAMPVDGyIsGL
0 1
PAK6 (human) VRGSAMPVDGyIsGL V78
PAK6 (mouse) VRGSSVPTEGYISGL T78
PAK6 (rat) VRGssVPtEGYIsGL T78-p
Y81-p
SAMPVDGyIsGLLND
Upstream
0 26
Treatment
  • MLN8054
PAK6 (human) SAMPVDGyIsGLLND Y81-p
PAK6 (mouse) SSVPTEGYISGLLND Y81
PAK6 (rat) ssVPtEGYIsGLLND Y81
S83-p
MPVDGyIsGLLNDIQ
Upstream
0 4
Treatment
  • MLN8054
PAK6 (human) MPVDGyIsGLLNDIQ S83-p
PAK6 (mouse) VPTEGYISGLLNDIQ S83
PAK6 (rat) VPtEGYIsGLLNDIQ S83-p
T99-p
LSVISSNtLRGRsPT
Downstream
2 6
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
PAK6 (human) LSVISSNtLRGRsPT T99-p
PAK6 (mouse) LSVISSNtLRGRSPT T99-p
PAK6 (rat) LSAISSNtLRGRSPT T99-p
S104-p
SNtLRGRsPTSRRRA
0 2
PAK6 (human) SNtLRGRsPTSRRRA S104-p
PAK6 (mouse) SNtLRGRSPTSRRRA S104
PAK6 (rat) SNtLRGRSPTSRRRA S104
S113-p
TSRRRAQsLGLLGDE
Upstream
Downstream
2 14
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
Kinase, in vitro:
  • Akt1 (mouse)
  • PKACA (human)
Treatment
  • androstanolone
  • H-89
  • IGF-1
  • NKH_477
  • PI-103
PAK6 (human) TSRRRAQsLGLLGDE S113-p
PAK6 (mouse) TSRRRAQSLGLLGDD S113
PAK6 (rat) TSRRRAQSLGLLGDD S113
Y129-p
WATDPDMyLQsPQsE
0 4
PAK6 (human) WATDPDMyLQsPQsE Y129-p
PAK6 (mouse) WAADPDMYLQSPQSE Y129
PAK6 (rat) WAADPDMYLQSPQSE Y129
S132-p
DPDMyLQsPQsERTD
0 12
PAK6 (human) DPDMyLQsPQsERTD S132-p
PAK6 (mouse) DPDMYLQSPQSEHTD S132
PAK6 (rat) DPDMYLQSPQSERTD S132
S135-p
MyLQsPQsERTDPHG
0 1
PAK6 (human) MyLQsPQsERTDPHG S135-p
PAK6 (mouse) MYLQSPQSEHTDPHG S135
PAK6 (rat) MYLQSPQSERTDPHG S135
Y144-p
RTDPHGLyLSCNGGT
0 52
PAK6 (human) RTDPHGLyLSCNGGT Y144-p
PAK6 (mouse) HTDPHGLYLSCNGGT Y144
PAK6 (rat) RTDPHGVYLSCNGGT Y144
S165-p
MPWPEPQsPRVLPNG
Upstream
Downstream
1 2
Effects on Modified Protein
  • enzymatic activity, induced
Putative in vivo kinases:
  • P38A (human)
Treatment
  • SB203580
PAK6 (human) MPWPEPQsPRVLPNG S165-p
PAK6 (mouse) VPWPEPQSPQALPNG S165
PAK6 (rat) TPWPEPQSPQALPNG S165
S179-p
GLAAKAQsLGPAEFQ
0 3
PAK6 (human) GLAAKAQsLGPAEFQ S179-p
PAK6 (mouse) GMAAKAQsLGPAEFQ S179-p
PAK6 (rat) GMAAKAQSLGPAEFQ S179
S207-p
QSSPPGAsPPTGTNR
0 3
PAK6 (human) QSSPPGAsPPTGTNR S207-p
PAK6 (mouse) QSSPPGTSPPMATGR S208
PAK6 (rat) QSSPPGTSPPMATGR S207
S246-p
GRPGGEGsPsPKTRE
0 3
PAK6 (human) GRPGGEGsPsPKTRE S246-p
PAK6 (mouse) GRPGGEGsPSPKNQE S247-p
PAK6 (rat) GRPGGEGSPSPKTQE S246
S248-p
PGGEGsPsPKTRESS
0 3
PAK6 (human) PGGEGsPsPKTRESS S248-p
PAK6 (mouse) PGGEGsPSPKNQESS S249
PAK6 (rat) PGGEGSPSPKTQESS S248
S308-p
SLVAKAQsLPSDQPV
Upstream
Downstream
1 1
Effects on Modified Protein
  • enzymatic activity, induced
  • molecular association, regulation
Effects on Biological Processes:
  • carcinogenesis, induced
  • cell motility, induced
Treatment
  • androstanolone
PAK6 (human) SLVAKAQsLPSDQPV S308-p
PAK6 (mouse) NLVAKAQSLPSEQPM S309
PAK6 (rat) NLVAKAQSLPSDQPT S308
T326-p
SPLTTSDtssPQKSL
Upstream
Downstream
1 2
Effects on Modified Protein
  • enzymatic activity, induced
  • molecular association, regulation
Effects on Biological Processes:
  • carcinogenesis, induced
  • cell motility, induced
Treatment
  • androstanolone
PAK6 (human) SPLTTSDtssPQKSL T326-p
PAK6 (mouse) SPLTTSDTSSPQKSL T327
PAK6 (rat) SPLTTSDTSSPQKSL T326
S327-p
PLTTSDtssPQKSLR
1 1
PAK6 (human) PLTTSDtssPQKSLR S327-p
PAK6 (mouse) PLTTSDTSSPQKSLR S328
PAK6 (rat) PLTTSDTSSPQKSLR S327
S328-p
LTTSDtssPQKSLRT
1 1
PAK6 (human) LTTSDtssPQKSLRT S328-p
PAK6 (mouse) LTTSDTSSPQKSLRT S329
PAK6 (rat) LTTSDTSSPQKSLRT S328
T339-p
SLRTAPAtGQLPGRs
0 1
PAK6 (human) SLRTAPAtGQLPGRs T339-p
PAK6 (mouse) SLRTAPAAGPLPGRS A340
PAK6 (rat) SLRTAPATGPLPGRS T339
S346-p
tGQLPGRssPAGsPR
Upstream
Downstream
1 2
Effects on Modified Protein
  • enzymatic activity, induced
  • molecular association, regulation
Effects on Biological Processes:
  • carcinogenesis, induced
  • cell motility, induced
Treatment
  • androstanolone
PAK6 (human) tGQLPGRssPAGsPR S346-p
PAK6 (mouse) AGPLPGRSSPAGsPR S347
PAK6 (rat) TGPLPGRSSPAGsPR S346
S347-p
GQLPGRssPAGsPRt
1 3
PAK6 (human) GQLPGRssPAGsPRt S347-p
PAK6 (mouse) GPLPGRSSPAGsPRT S348
PAK6 (rat) GPLPGRSSPAGsPRT S347
S351-p
GRssPAGsPRtWHAQ
0 6
PAK6 (human) GRssPAGsPRtWHAQ S351-p
PAK6 (mouse) GRSSPAGsPRTRHAQ S352-p
PAK6 (rat) GRSSPAGsPRTRHAQ S351-p
T354-p
sPAGsPRtWHAQIsT
Downstream
1 1
Effects on Modified Protein
  • enzymatic activity, induced
  • molecular association, regulation
Effects on Biological Processes:
  • carcinogenesis, induced
  • cell motility, induced
PAK6 (human) sPAGsPRtWHAQIsT T354-p
PAK6 (mouse) SPAGsPRTRHAQIST T355
PAK6 (rat) SPAGsPRTRHAQIST T354
S360-p
RtWHAQIsTSNLyLP
Upstream
Downstream
1 1
Effects on Modified Protein
  • enzymatic activity, induced
  • molecular association, regulation
Effects on Biological Processes:
  • carcinogenesis, induced
  • cell motility, induced
Treatment
  • androstanolone
PAK6 (human) RtWHAQIsTSNLyLP S360-p
PAK6 (mouse) RTRHAQISTsNLYLP S361
PAK6 (rat) RTRHAQISTSNLYLP S360
S362
WHAQIsTSNLyLPQD
0 1
PAK6 (human) WHAQIsTSNLyLPQD S362
PAK6 (mouse) RHAQISTsNLYLPQD S363-p
PAK6 (rat) RHAQISTSNLYLPQD S362
Y365-p
QIsTSNLyLPQDPtV
0 14
PAK6 (human) QIsTSNLyLPQDPtV Y365-p
PAK6 (mouse) QISTsNLYLPQDPTV Y366
PAK6 (rat) QISTSNLYLPQDPTV Y365
T371-p
LyLPQDPtVAKGALA
0 1
PAK6 (human) LyLPQDPtVAKGALA T371-p
PAK6 (mouse) LYLPQDPTVAKGALG T372
PAK6 (rat) LYLPQDPTVAKGALG T371
K528-ub
GVIHRDIkSDSILLT
0 1
PAK6 (human) GVIHRDIkSDSILLT K528-ub
PAK6 (mouse) GVIHRDIKSDSILLT K529
PAK6 (rat) GVIHRDIKSDSILLT K528
S560-p
KDVPKRKsLVGtPyW
Upstream
Downstream
2 56
PAK6 (human)
S560-p
PAK6 (mouse)
S561-p
PAK6 (rat)
S560-p
Effects on Modified Protein
  • enzymatic activity, induced
Treatment
  • androstanolone
PAK6 (human) KDVPKRKsLVGtPyW S560-p
PAK6 (mouse) KDVPKRKsLVGtPYW S561-p
PAK6 (rat) KDVPKRKsLVGTPYW S560-p
T564-p
KRKsLVGtPyWMAPE
0 18
PAK6 (human) KRKsLVGtPyWMAPE T564-p
PAK6 (mouse) KRKsLVGtPYWMAPE T565-p
PAK6 (rat) KRKsLVGTPYWMAPE T564
Y566-p
KsLVGtPyWMAPEVI
Upstream
Downstream
1 0
Effects on Modified Protein
  • enzymatic activity, induced
Putative in vivo kinases:
  • MKK6 (human)
PAK6 (human) KsLVGtPyWMAPEVI Y566-p
PAK6 (mouse) KsLVGtPYWMAPEVI Y567
PAK6 (rat) KsLVGTPYWMAPEVI Y566
S616-p
AMKRLRDsPPPKLKN
0 3
PAK6 (human) AMKRLRDsPPPKLKN S616-p
PAK6 (mouse) AMKRLRDSAPPKLKN S617
PAK6 (rat) AMKRLRDSPPPKLKN S616