Other Species / Isoforms
  NEK2 (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

  HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
K37-ub
DGKILVWkELDYGSM
0 1
NEK2 (human) DGKILVWkELDYGSM K37-ub
NEK2 iso2 (human) DGKILVWKELDYGSM K37
NEK2 (mouse) DGKILVWKELDYGSM K37
NEK2 (rat) DGKILVWKELDYGSM K33
K143-ub
TVLHRDLkPANVFLD
0 3
NEK2 (human) TVLHRDLkPANVFLD K143-ub
NEK2 iso2 (human) TVLHRDLKPANVFLD K143
NEK2 (mouse) TVLHRDLKPANVFLD K143
NEK2 (rat) TVLHRDLKPANVFLD K139
K152-ub
ANVFLDGkQNVkLGD
0 4
NEK2 (human) ANVFLDGkQNVkLGD K152-ub
NEK2 iso2 (human) ANVFLDGKQNVKLGD K152
NEK2 (mouse) ANVFLDSKHNVKLGD K152
NEK2 (rat) ANVFLDSKHNVKLGD K148
K156-ub
LDGkQNVkLGDFGLA
0 4
NEK2 (human) LDGkQNVkLGDFGLA K156-ub
NEK2 iso2 (human) LDGKQNVKLGDFGLA K156
NEK2 (mouse) LDSKHNVKLGDFGLA K156
NEK2 (rat) LDSKHNVKLGDFGLA K152
T170-p
ARILNHDtsFAktFV
Upstream
Downstream
0 1
Effects on Modified Protein
  • enzymatic activity, induced
Kinase, in vitro:
  • NEK2 (human)
NEK2 (human) ARILNHDtsFAktFV T170-p
NEK2 iso2 (human) ARILNHDTSFAKTFV T170
NEK2 (mouse) ARILNHDTsFAKTFV T170
NEK2 (rat) ARILNHDTSFAKtFV T166
S171-p
RILNHDtsFAktFVG
Upstream
Downstream
0 5
Effects on Modified Protein
  • enzymatic activity, induced
Kinase, in vitro:
  • NEK2 (human)
Treatment
  • MG132_withdrawal
NEK2 (human) RILNHDtsFAktFVG S171-p
NEK2 iso2 (human) RILNHDTSFAKTFVG S171
NEK2 (mouse) RILNHDTsFAKTFVG S171-p
NEK2 (rat) RILNHDTSFAKtFVG S167
K174-ub
NHDtsFAktFVGtPY
0 2
NEK2 (human) NHDtsFAktFVGtPY K174-ub
NEK2 iso2 (human) NHDTSFAKTFVGTPY K174
NEK2 (mouse) NHDTsFAKTFVGTPY K174
NEK2 (rat) NHDTSFAKtFVGtPY K170
T175-p
HDtsFAktFVGtPYY
Upstream
Downstream
0 2
Effects on Modified Protein
  • enzymatic activity, induced
Kinase, in vitro:
  • NEK2 (human)
NEK2 (human) HDtsFAktFVGtPYY T175-p
NEK2 iso2 (human) HDTSFAKTFVGTPYY T175
NEK2 (mouse) HDTsFAKTFVGTPYY T175
NEK2 (rat) HDTSFAKtFVGtPYY T171-p
T179-p
FAktFVGtPYYMsPE
Upstream
Downstream
0 2
Effects on Modified Protein
  • enzymatic activity, inhibited
Kinase, in vitro:
  • NEK2 (human)
NEK2 (human) FAktFVGtPYYMsPE T179-p
NEK2 iso2 (human) FAKTFVGTPYYMSPE T179
NEK2 (mouse) FAKTFVGTPYYMSPE T179
NEK2 (rat) FAKtFVGtPYYMsPE T175-p
S184-p
VGtPYYMsPEQMNRM
Upstream
0 7
Treatment
  • nocodazole
  • thymidine
NEK2 (human) VGtPYYMsPEQMNRM S184-p
NEK2 iso2 (human) VGTPYYMSPEQMNRM S184
NEK2 (mouse) VGTPYYMSPEQMSCL S184
NEK2 (rat) VGtPYYMsPEQISRL S180-p
K227-ub
SQKELAGkIREGKFR
0 2
NEK2 (human) SQKELAGkIREGKFR K227-ub
NEK2 iso2 (human) SQKELAGKIREGKFR K227
NEK2 (mouse) NQKELAGKIREGRFR K227
NEK2 (rat) NQKELAGKIREGRFR K224
S241-p
RRIPYRYsDELNEII
Upstream
Downstream
0 1
Effects on Modified Protein
  • enzymatic activity, inhibited
Kinase, in vitro:
  • NEK2 (human)
NEK2 (human) RRIPYRYsDELNEII S241-p
NEK2 iso2 (human) RRIPYRYSDELNEII S241
NEK2 (mouse) RRIPYRYSDGLNDLI S241
NEK2 (rat) RRIPYRYSDGLNDLI S238
S261-p
LKDYHRPsVEEILEN
0 1
NEK2 (human) LKDYHRPsVEEILEN S261-p
NEK2 iso2 (human) LKDYHRPSVEEILEN S261
NEK2 (mouse) LKDYHRPSVEEILES S261
NEK2 (rat) LKDYHRPSVEEILES S258
L290
LERRGRQLGEPEksQ
0 1
NEK2 (human) LERRGRQLGEPEksQ L290
NEK2 iso2 (human) LERRGRQLGEPEKSQ L290
NEK2 (mouse) LERRGRRsGEPsKLP S290-p
NEK2 (rat) LERRGRRSGEPSKLQ S287
E294
GRQLGEPEksQDSsP
0 1
NEK2 (human) GRQLGEPEksQDSsP E294
NEK2 iso2 (human) GRQLGEPEKSQDSSP E294
NEK2 (mouse) GRRsGEPsKLPDSsP S294-p
NEK2 (rat) GRRSGEPSKLQDSsP S291
K295-ub
RQLGEPEksQDSsPV
0 2
NEK2 (human) RQLGEPEksQDSsPV K295-ub
NEK2 iso2 (human) RQLGEPEKSQDSSPV K295
NEK2 (mouse) RRsGEPsKLPDSsPV K295
NEK2 (rat) RRSGEPSKLQDSsPV K292
S296-p
QLGEPEksQDSsPVL
Upstream
0 5
Treatment
  • nocodazole
  • thymidine
NEK2 (human) QLGEPEksQDSsPVL S296-p
NEK2 iso2 (human) QLGEPEKSQDSSPVL S296
NEK2 (mouse) RsGEPsKLPDSsPVL L296
NEK2 (rat) RSGEPSKLQDSsPVL L293
S300-p
PEksQDSsPVLsELk
Upstream
0 7
Treatment
  • nocodazole
  • thymidine
NEK2 (human) PEksQDSsPVLsELk S300-p
NEK2 iso2 (human) PEKSQDSSPVLSELK S300
NEK2 (mouse) PsKLPDSsPVLSELK S300-p
NEK2 (rat) PSKLQDSsPVLSELK S297-p
S304-p
QDSsPVLsELkLkEI
0 1
NEK2 (human) QDSsPVLsELkLkEI S304-p
NEK2 iso2 (human) QDSSPVLSELKLKEI S304
NEK2 (mouse) PDSsPVLSELKLKER S304
NEK2 (rat) QDSsPVLSELKLKER S301
K307-ub
sPVLsELkLkEIQLQ
0 1
NEK2 (human) sPVLsELkLkEIQLQ K307-ub
NEK2 iso2 (human) SPVLSELKLKEIQLQ K307
NEK2 (mouse) sPVLSELKLKERQLQ K307
NEK2 (rat) sPVLSELKLKERQLQ K304
K309-ub
VLsELkLkEIQLQER
0 2
NEK2 (human) VLsELkLkEIQLQER K309-ub
NEK2 iso2 (human) VLSELKLKEIQLQER K309
NEK2 (mouse) VLSELKLKERQLQDR K309
NEK2 (rat) VLSELKLKERQLQDR K306
K330-ub
REERLEQkEQELCVR
0 2
NEK2 (human) REERLEQkEQELCVR K330-ub
NEK2 iso2 (human) REERLEQKEQELCVR K330
NEK2 (mouse) REDILEQKERELCIR K330
NEK2 (rat) REDSLEQKERELCIR K327
K344-ub
RERLAEDkLARAENL
0 2
NEK2 (human) RERLAEDkLARAENL K344-ub
NEK2 iso2 (human) RERLAEDKLARAENL K344
NEK2 (mouse) RERLAEDKLARAESL K344
NEK2 (rat) RERLAEDKLARAESL K341
K353-ub
ARAENLLkNYsLLkE
0 2
NEK2 (human) ARAENLLkNYsLLkE K353-ub
NEK2 iso2 (human) ARAENLLKNYSLLKE K353
NEK2 (mouse) ARAESLMKNYSLLKE K353
NEK2 (rat) ARAESLLKNYSLLKE K350
S356-p
ENLLkNYsLLkERkF
Upstream
1 2
Kinase, in vitro:
  • MST2 (human)
  • NEK2 (human)
NEK2 (human) ENLLkNYsLLkERkF S356-p
NEK2 iso2 (human) ENLLKNYSLLKERKF S356
NEK2 (mouse) ESLMKNYSLLKEHRL S356
NEK2 (rat) ESLLKNYSLLKEHRL S353
K359-ub
LkNYsLLkERkFLsL
0 2
NEK2 (human) LkNYsLLkERkFLsL K359-ub
NEK2 iso2 (human) LKNYSLLKERKFLsL K359
NEK2 (mouse) MKNYSLLKEHRLLCL K359
NEK2 (rat) LKNYSLLKEHRLLCL K356
K362-ub
YsLLkERkFLsLASN
0 3
NEK2 (human) YsLLkERkFLsLASN K362-ub
NEK2 iso2 (human) YSLLKERKFLsLAsN K362
NEK2 (mouse) YSLLKEHRLLCLAGG R362
NEK2 (rat) YSLLKEHRLLCLAGG R359
S365-p
LkERkFLsLASNPEL
Upstream
1 3
Kinase, in vitro:
  • MST2 (human)
NEK2 (human) LkERkFLsLASNPEL S365-p
NEK2 iso2 (human) LKERKFLsLAsNPGM S365-p
NEK2 (mouse) LKEHRLLCLAGGPEL C365
NEK2 (rat) LKEHRLLCLAGGSEL C362
S368
RkFLsLASNPELLNL
0 1
NEK2 (human) RkFLsLASNPELLNL S368
NEK2 iso2 (human) RKFLsLAsNPGMRIN S368-p
NEK2 (mouse) HRLLCLAGGPELDLP G368
NEK2 (rat) HRLLCLAGGSELDLP G365
S378-p
ELLNLPSsVIkKkVH
0 1
NEK2 (human) ELLNLPSsVIkKkVH S378-p
NEK2 iso2 (human) gap -
NEK2 (mouse) PELDLPSSAMKKKVH S377
NEK2 (rat) SELDLPSSALKKKVH S374
K381-ub
NLPSsVIkKkVHFSG
0 1
NEK2 (human) NLPSsVIkKkVHFSG K381-ub
NEK2 iso2 (human) gap -
NEK2 (mouse) DLPSSAMKKKVHFHG K380
NEK2 (rat) DLPSSALKKKVHFHG K377
K383-ub
PSsVIkKkVHFSGEs
0 1
NEK2 (human) PSsVIkKkVHFSGEs K383-ub
NEK2 iso2 (human) gap -
NEK2 (mouse) PSSAMKKKVHFHGES K382
NEK2 (rat) PSSALKKKVHFHGES K379
S390-p
kVHFSGEskENIMRs
0 1
NEK2 (human) kVHFSGEskENIMRs S390-p
NEK2 iso2 (human) gap -
NEK2 (mouse) KVHFHGESKENTARS S389
NEK2 (rat) KVHFHGESKENTARS S386
K391-ub
VHFSGEskENIMRsE
0 4
NEK2 (human) VHFSGEskENIMRsE K391-ub
NEK2 iso2 (human) gap -
NEK2 (mouse) VHFHGESKENTARSE K390
NEK2 (rat) VHFHGESKENTARS_ K387
S397-p
skENIMRsENsEsQL
Upstream
0 3
Kinase, in vitro:
  • NEK2 (human)
NEK2 (human) skENIMRsENsEsQL S397-p
NEK2 iso2 (human) gap -
NEK2 (mouse) SKENTARSENSESYL S396
NEK2 (rat) SKENTARS_______ S393
S400-p
NIMRsENsEsQLtsk
0 3
NEK2 (human) NIMRsENsEsQLtsk S400-p
NEK2 iso2 (human) gap -
NEK2 (mouse) NTARSENSESYLAKS S399
NEK2 (rat) gap -
S402-p
MRsENsEsQLtsksK
Upstream
0 3
Kinase, in vitro:
  • NEK2 (human)
NEK2 (human) MRsENsEsQLtsksK S402-p
NEK2 iso2 (human) gap -
NEK2 (mouse) ARSENSESYLAKSKC S401
NEK2 (rat) gap -
T405-p
ENsEsQLtsksKCKD
0 1
NEK2 (human) ENsEsQLtsksKCKD T405-p
NEK2 iso2 (human) gap -
NEK2 (mouse) gap -
NEK2 (rat) gap -
S406-p
NsEsQLtsksKCKDL
Upstream
1 1
Kinase, in vitro:
  • MST2 (human)
NEK2 (human) NsEsQLtsksKCKDL S406-p
NEK2 iso2 (human) gap -
NEK2 (mouse) ENSESYLAKSKCRDL A404
NEK2 (rat) gap -
K407-ub
sEsQLtsksKCKDLK
0 1
NEK2 (human) sEsQLtsksKCKDLK K407-ub
NEK2 iso2 (human) gap -
NEK2 (mouse) NSESYLAKSKCRDLK K405
NEK2 (rat) gap -
S408-p
EsQLtsksKCKDLKK
0 1
NEK2 (human) EsQLtsksKCKDLKK S408-p
NEK2 iso2 (human) gap -
NEK2 (mouse) SESYLAKSKCRDLKK S406
NEK2 (rat) gap -
S428-p
QLRAQALsDIEkNYQ
Upstream
0 1
Kinase, in vitro:
  • NEK2 (human)
NEK2 (human) QLRAQALsDIEkNYQ S428-p
NEK2 iso2 (human) gap -
NEK2 (mouse) QLRAQALADIEKNYQ A426
NEK2 (rat) gap -
K432-ub
QALsDIEkNYQLksR
0 1
NEK2 (human) QALsDIEkNYQLksR K432-ub
NEK2 iso2 (human) gap -
NEK2 (mouse) QALADIEKNYQLKSR K430
NEK2 (rat) gap -
K437-ac
IEkNYQLksRQILGM
0 1
NEK2 (human) IEkNYQLksRQILGM K437-ac
NEK2 iso2 (human) gap -
NEK2 (mouse) IEKNYQLKSRQILGM K435
NEK2 (rat) gap -
K437-ub
IEkNYQLksRQILGM
0 2
NEK2 (human) IEkNYQLksRQILGM K437-ub
NEK2 iso2 (human) gap -
NEK2 (mouse) IEKNYQLKSRQILGM K435
NEK2 (rat) gap -
S438-p
EkNYQLksRQILGMR
Upstream
1 0
Kinase, in vitro:
  • MST2 (human)
Putative in vivo kinases:
  • MST2 (human)
NEK2 (human) EkNYQLksRQILGMR S438-p
NEK2 iso2 (human) gap -
NEK2 (mouse) EKNYQLKSRQILGMR S436
NEK2 (rat) gap -