Other Species / Isoforms
  fumarase (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

 HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
S46-p
PNAARMAsQNSFRIE
Upstream
Downstream
1 5
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
Effects on Biological Processes:
  • carcinogenesis, induced
  • cell growth, induced
  • signaling pathway regulation
Kinase, in vitro:
  • PAK4 (human)
Putative in vivo kinases:
  • PAK4 (human)
Treatment
  • PF-03758309
fumarase (human) PNAARMAsQNSFRIE S46-p
fumarase iso2 (human) _____MASQNSFRIE S3
fumarase (mouse) PNVARMAsQNSFRVE S43-p
fumarase (rat) PNVVRMASQNSFRIE S43
Y54-p
QNSFRIEyDTFGELk
0 5
fumarase (human) QNSFRIEyDTFGELk Y54-p
fumarase iso2 (human) QNSFRIEYDTFGELK Y11
fumarase (mouse) QNSFRVEFDTFGELk F51
fumarase (rat) QNSFRIEYDTFGELk Y51
K61-ac
yDTFGELkVPNDkyy
0 5
fumarase (human) yDTFGELkVPNDkyy K61-ac
fumarase iso2 (human) YDTFGELKVPNDKYY K18
fumarase (mouse) FDTFGELkVPTDkYY K58-ac
fumarase (rat) YDTFGELkVPTDkYY K58-ac
K61-ub
yDTFGELkVPNDkyy
0 2
fumarase (human) yDTFGELkVPNDkyy K61-ub
fumarase iso2 (human) YDTFGELKVPNDKYY K18
fumarase (mouse) FDTFGELkVPTDkYY K58-ub
fumarase (rat) YDTFGELKVPTDkYY K58
K61
yDTFGELKVPNDkyy
0 2
fumarase (human) yDTFGELKVPNDkyy K61
fumarase iso2 (human) YDTFGELKVPNDKYY K18
fumarase (mouse) FDTFGELkVPTDkYY K58-sc
fumarase (rat) YDTFGELKVPTDkYY K58
K66-ac
ELkVPNDkyyGAQTV
Upstream
0 21
Treatment
  • MS275
fumarase (human) ELkVPNDkyyGAQTV K66-ac
fumarase iso2 (human) ELKVPNDKYYGAQTV K23
fumarase (mouse) ELkVPTDkYYGAQTV K63-ac
fumarase (rat) ELkVPTDkYYGAQTV K63-ac
K66-ub
ELkVPNDkyyGAQTV
0 3
fumarase (human) ELkVPNDkyyGAQTV K66-ub
fumarase iso2 (human) ELKVPNDKYYGAQTV K23
fumarase (mouse) ELkVPTDkYYGAQTV K63-ub
fumarase (rat) ELkVPTDKYYGAQTV K63
K66-sc
ELkVPNDkyyGAQTV
0 2
fumarase (human) ELkVPNDkyyGAQTV K66-sc
fumarase iso2 (human) ELKVPNDKYYGAQTV K23
fumarase (mouse) ELkVPTDkYYGAQTV K63-sc
fumarase (rat) ELkVPTDKYYGAQTV K63
Y67-p
LkVPNDkyyGAQTVR
0 2
fumarase (human) LkVPNDkyyGAQTVR Y67-p
fumarase iso2 (human) LKVPNDKYYGAQTVR Y24
fumarase (mouse) LkVPTDkYYGAQTVR Y64
fumarase (rat) LkVPTDkYYGAQTVR Y64
Y68-p
kVPNDkyyGAQTVRs
0 3
fumarase (human) kVPNDkyyGAQTVRs Y68-p
fumarase iso2 (human) KVPNDKYYGAQTVRS Y25
fumarase (mouse) kVPTDkYYGAQTVRS Y65
fumarase (rat) kVPTDkYYGAQTVRS Y65
S75-p
yGAQTVRsTMNFkIG
Upstream
Downstream
1 1
Effects on Modified Protein
  • molecular association, regulation
Effects on Biological Processes:
  • cell growth, induced
  • transcription, induced
Kinase, in vitro:
  • AMPKA1 (human)
Putative in vivo kinases:
  • AMPKA1 (human)
Treatment
  • glucose_starvation
fumarase (human) yGAQTVRsTMNFkIG S75-p
fumarase iso2 (human) YGAQTVRSTMNFKIG S32
fumarase (mouse) YGAQTVRSTMNFkIG S72
fumarase (rat) YGAQTVRSTMNFkIG S72
K80-ac
VRsTMNFkIGGVtER
0 42
fumarase (human) VRsTMNFkIGGVtER K80-ac
fumarase iso2 (human) VRSTMNFKIGGVTER K37
fumarase (mouse) VRSTMNFkIGGAtER K77-ac
fumarase (rat) VRSTMNFkIGGATER K77-ac
K80
VRsTMNFKIGGVtER
0 1
fumarase (human) VRsTMNFKIGGVtER K80
fumarase iso2 (human) VRSTMNFKIGGVTER K37
fumarase (mouse) VRSTMNFkIGGAtER K77-ub
fumarase (rat) VRSTMNFKIGGATER K77
K80-sc
VRsTMNFkIGGVtER
0 2
fumarase (human) VRsTMNFkIGGVtER K80-sc
fumarase iso2 (human) VRSTMNFKIGGVTER K37
fumarase (mouse) VRSTMNFkIGGAtER K77-sc
fumarase (rat) VRSTMNFKIGGATER K77
T85-p
NFkIGGVtERMPtPV
0 7
fumarase (human) NFkIGGVtERMPtPV T85-p
fumarase iso2 (human) NFKIGGVTERMPTPV T42
fumarase (mouse) NFkIGGAtERMPIPV T82-p
fumarase (rat) NFkIGGATERMPIPV T82
T90-p
GVtERMPtPVIkAFG
Upstream
Downstream
1 12
Effects on Modified Protein
  • molecular association, regulation
Effects on Biological Processes:
  • carcinogenesis, inhibited
  • cell growth, inhibited
  • signaling pathway regulation
  • transcription, induced
Kinase, in vitro:
  • P38A (human)
Regulatory protein:
  • P38A (human)
Treatment
  • TGF-beta
fumarase (human) GVtERMPtPVIkAFG T90-p
fumarase iso2 (human) GVTERMPTPVIKAFG T47
fumarase (mouse) GAtERMPIPVIQAFG I87
fumarase (rat) GATERMPIPVIkAFG I87
K94-ac
RMPtPVIkAFGILkR
0 8
fumarase (human) RMPtPVIkAFGILkR K94-ac
fumarase iso2 (human) RMPTPVIKAFGILKR K51
fumarase (mouse) RMPIPVIQAFGILkR Q91
fumarase (rat) RMPIPVIkAFGILkR K91-ac
K94-ub
RMPtPVIkAFGILkR
0 9
fumarase (human) RMPtPVIkAFGILkR K94-ub
fumarase iso2 (human) RMPTPVIKAFGILKR K51
fumarase (mouse) RMPIPVIQAFGILkR Q91
fumarase (rat) RMPIPVIKAFGILkR K91
K94-sc
RMPtPVIkAFGILkR
0 1
fumarase (human) RMPtPVIkAFGILkR K94-sc
fumarase iso2 (human) RMPTPVIKAFGILKR K51
fumarase (mouse) RMPIPVIQAFGILkR Q91
fumarase (rat) RMPIPVIKAFGILkR K91
K100-ub
IkAFGILkRAAAEVN
0 4
fumarase (human) IkAFGILkRAAAEVN K100-ub
fumarase iso2 (human) IKAFGILKRAAAEVN K57
fumarase (mouse) IQAFGILkRAAAEVN K97-ub
fumarase (rat) IkAFGILKRAAAEVN K97
K100
IkAFGILKRAAAEVN
0 1
fumarase (human) IkAFGILKRAAAEVN K100
fumarase iso2 (human) IKAFGILKRAAAEVN K57
fumarase (mouse) IQAFGILKRAAAEVN K97
fumarase (rat) IkAFGILkRAAAEVN K97-ac
K100-m1
IkAFGILkRAAAEVN
0 1
fumarase (human) IkAFGILkRAAAEVN K100-m1
fumarase iso2 (human) IKAFGILKRAAAEVN K57
fumarase (mouse) IQAFGILKRAAAEVN K97
fumarase (rat) IkAFGILKRAAAEVN K97
Y110-p
AAEVNQDyGLDPkIA
0 2
fumarase (human) AAEVNQDyGLDPkIA Y110-p
fumarase iso2 (human) AAEVNQDYGLDPKIA Y67
fumarase (mouse) AAEVNQEYGLDPkIA Y107
fumarase (rat) AAEVNQEYGLDPkIA Y107
K115-ac
QDyGLDPkIANAIMk
0 7
fumarase (human) QDyGLDPkIANAIMk K115-ac
fumarase iso2 (human) QDYGLDPKIANAIMK K72
fumarase (mouse) QEYGLDPkIAsAIMk K112-ac
fumarase (rat) QEYGLDPkIASAIMk K112-ac
K115-ub
QDyGLDPkIANAIMk
0 2
fumarase (human) QDyGLDPkIANAIMk K115-ub
fumarase iso2 (human) QDYGLDPKIANAIMK K72
fumarase (mouse) QEYGLDPkIAsAIMk K112-ub
fumarase (rat) QEYGLDPKIASAIMk K112
K115
QDyGLDPKIANAIMk
0 2
fumarase (human) QDyGLDPKIANAIMk K115
fumarase iso2 (human) QDYGLDPKIANAIMK K72
fumarase (mouse) QEYGLDPkIAsAIMk K112-sc
fumarase (rat) QEYGLDPKIASAIMk K112
N118
GLDPkIANAIMkAAD
0 1
fumarase (human) GLDPkIANAIMkAAD N118
fumarase iso2 (human) GLDPKIANAIMKAAD N75
fumarase (mouse) GLDPkIAsAIMkAAD S115-p
fumarase (rat) GLDPkIASAIMkAAD S115
K122-ac
kIANAIMkAADEVAE
0 3
fumarase (human) kIANAIMkAADEVAE K122-ac
fumarase iso2 (human) KIANAIMKAADEVAE K79
fumarase (mouse) kIAsAIMkAADEVAE K119-ac
fumarase (rat) kIASAIMkAADEVAE K119-ac
K122
kIANAIMKAADEVAE
0 1
fumarase (human) kIANAIMKAADEVAE K122
fumarase iso2 (human) KIANAIMKAADEVAE K79
fumarase (mouse) kIAsAIMkAADEVAE K119-ub
fumarase (rat) kIASAIMKAADEVAE K119
K122-sc
kIANAIMkAADEVAE
0 2
fumarase (human) kIANAIMkAADEVAE K122-sc
fumarase iso2 (human) KIANAIMKAADEVAE K79
fumarase (mouse) kIAsAIMkAADEVAE K119-sc
fumarase (rat) kIASAIMKAADEVAE K119
K131
ADEVAEGKLNDHFPL
0 3
fumarase (human) ADEVAEGKLNDHFPL K131
fumarase iso2 (human) ADEVAEGKLNDHFPL K88
fumarase (mouse) ADEVAEGkLNDHFPL K128-ac
fumarase (rat) ADEVAEGkLNDHFPL K128-ac
S171-p
MLGGELGskIPVHPN
1 2
fumarase (human) MLGGELGskIPVHPN S171-p
fumarase iso2 (human) MLGGELGsKIPVHPN S128-p
fumarase (mouse) MLGGELGSkkPVHPN S168
fumarase (rat) MLGGELGSkkPVHPN S168
K172-ac
LGGELGskIPVHPND
0 3
fumarase (human) LGGELGskIPVHPND K172-ac
fumarase iso2 (human) LGGELGsKIPVHPND K129
fumarase (mouse) LGGELGSkkPVHPND K169-ac
fumarase (rat) LGGELGSkkPVHPND K169-ac
K172-ub
LGGELGskIPVHPND
0 1
fumarase (human) LGGELGskIPVHPND K172-ub
fumarase iso2 (human) LGGELGsKIPVHPND K129
fumarase (mouse) LGGELGSKkPVHPND K169
fumarase (rat) LGGELGSKkPVHPND K169
I173
GGELGskIPVHPNDH
0 2
fumarase (human) GGELGskIPVHPNDH I173
fumarase iso2 (human) GGELGsKIPVHPNDH I130
fumarase (mouse) GGELGSkkPVHPNDH K170-ac
fumarase (rat) GGELGSkkPVHPNDH K170-ac
K183
HPNDHVNKSQSSNDT
0 1
fumarase (human) HPNDHVNKSQSSNDT K183
fumarase iso2 (human) HPNDHVNKSQSSNDT K140
fumarase (mouse) HPNDHVNkSQSSNDT K180-sc
fumarase (rat) HPNDHVNKSQSSNDT K180
E205
AAAIEVHEVLLPGLQ
0 1
fumarase (human) AAAIEVHEVLLPGLQ E205
fumarase iso2 (human) AAAIEVHEVLLPGLQ E162
fumarase (mouse) AAAVEVHkVLLPGLQ K202-ac
fumarase (rat) AAALEVHQVLLPGLQ Q202
K213
VLLPGLQKLHDALDA
0 1
fumarase (human) VLLPGLQKLHDALDA K213
fumarase iso2 (human) VLLPGLQKLHDALDA K170
fumarase (mouse) VLLPGLQkLHDALSA K210-ac
fumarase (rat) VLLPGLQKLHDALSA K210
K221-sc
LHDALDAkSkEFAQI
0 1
fumarase (human) LHDALDAkSkEFAQI K221-sc
fumarase iso2 (human) LHDALDAKSKEFAQI K178
fumarase (mouse) LHDALSAKSkEFAQV K218
fumarase (rat) LHDALSAKSkEFAQV K218
K221-ub
LHDALDAkSkEFAQI
0 1
fumarase (human) LHDALDAkSkEFAQI K221-ub
fumarase iso2 (human) LHDALDAKSKEFAQI K178
fumarase (mouse) LHDALSAKSkEFAQV K218
fumarase (rat) LHDALSAKSkEFAQV K218
K223
DALDAkSKEFAQIIk
0 7
fumarase (human) DALDAkSKEFAQIIk K223
fumarase iso2 (human) DALDAKSKEFAQIIK K180
fumarase (mouse) DALSAKSkEFAQVIK K220-ac
fumarase (rat) DALSAKSkEFAQVIK K220-ac
K223-ub
DALDAkSkEFAQIIk
0 2
fumarase (human) DALDAkSkEFAQIIk K223-ub
fumarase iso2 (human) DALDAKSKEFAQIIK K180
fumarase (mouse) DALSAKSkEFAQVIK K220-ub
fumarase (rat) DALSAKSKEFAQVIK K220
K223
DALDAkSKEFAQIIk
0 2
fumarase (human) DALDAkSKEFAQIIk K223
fumarase iso2 (human) DALDAKSKEFAQIIK K180
fumarase (mouse) DALSAKSkEFAQVIK K220-sc
fumarase (rat) DALSAKSKEFAQVIK K220
K230-ub
kEFAQIIkIGRTHtQ
0 2
fumarase (human) kEFAQIIkIGRTHtQ K230-ub
fumarase iso2 (human) KEFAQIIKIGRTHTQ K187
fumarase (mouse) kEFAQVIKIGRTHTQ K227
fumarase (rat) kEFAQVIKIGRTHTQ K227
T236-p
IkIGRTHtQDAVPLT
Upstream
Downstream
1 0
Effects on Modified Protein
  • molecular association, regulation
Kinase, in vitro:
  • DNAPK (human)
Putative in vivo kinases:
  • DNAPK (human)
Treatment
  • ionizing_radiation
fumarase (human) IkIGRTHtQDAVPLT T236-p
fumarase iso2 (human) IKIGRTHTQDAVPLT T193
fumarase (mouse) IKIGRTHTQDAVPLT T233
fumarase (rat) IKIGRTHTQDAVPLT T233
Y251-p
LGQEFSGyVQQVkYA
0 1
fumarase (human) LGQEFSGyVQQVkYA Y251-p
fumarase iso2 (human) LGQEFSGYVQQVKYA Y208
fumarase (mouse) LGQEFSGYVQQVQYA Y248
fumarase (rat) LGQEFSGYVQQVQYA Y248
K256-ac
SGyVQQVkYAMTRIK
0 8
fumarase (human) SGyVQQVkYAMTRIK K256-ac
fumarase iso2 (human) SGYVQQVKYAMTRIK K213
fumarase (mouse) SGYVQQVQYAMVRIk Q253
fumarase (rat) SGYVQQVQYAMERIK Q253
K263
kYAMTRIKAAMPRIY
0 1
fumarase (human) kYAMTRIKAAMPRIY K263
fumarase iso2 (human) KYAMTRIKAAMPRIY K220
fumarase (mouse) QYAMVRIkAAMPRIY K260-ac
fumarase (rat) QYAMERIKAAMPRIY K260
K292-ac
TRIGFAEkVAAKVAA
0 11
fumarase (human) TRIGFAEkVAAKVAA K292-ac
fumarase iso2 (human) TRIGFAEKVAAKVAA K249
fumarase (mouse) TRIGFAEkVAAKVAA K289-ac
fumarase (rat) TRIGFAEkVAAKVAA K289-ac
K292-ub
TRIGFAEkVAAKVAA
0 4
fumarase (human) TRIGFAEkVAAKVAA K292-ub
fumarase iso2 (human) TRIGFAEKVAAKVAA K249
fumarase (mouse) TRIGFAEkVAAKVAA K289-ub
fumarase (rat) TRIGFAEKVAAKVAA K289
K292-sc
TRIGFAEkVAAKVAA
0 2
fumarase (human) TRIGFAEkVAAKVAA K292-sc
fumarase iso2 (human) TRIGFAEKVAAKVAA K249
fumarase (mouse) TRIGFAEkVAAKVAA K289-sc
fumarase (rat) TRIGFAEKVAAKVAA K289
T301-p
AAKVAALtGLPFVTA
0 1
fumarase (human) AAKVAALtGLPFVTA T301-p
fumarase iso2 (human) AAKVAALTGLPFVTA T258
fumarase (mouse) AAKVAALTGLPFVTA T298
fumarase (rat) AAKVAALTGLPFVTA T298
R343-m1
MKIANDIrFLGSGPR
0 1
fumarase (human) MKIANDIrFLGSGPR R343-m1
fumarase iso2 (human) MKIANDIRFLGSGPR R300
fumarase (mouse) MKIANDIRFLGSGPR R340
fumarase (rat) MKIANDIRFLGSGPR R340
S351-p
FLGSGPRsGLGELIL
0 1
fumarase (human) FLGSGPRsGLGELIL S351-p
fumarase iso2 (human) FLGSGPRSGLGELIL S308
fumarase (mouse) FLGSGPRSGLGELIL S348
fumarase (rat) FLGSGPRSGLGELIL S348
S366-p
PENEPGSsIMPGKVN
0 5
fumarase (human) PENEPGSsIMPGKVN S366-p
fumarase iso2 (human) PENEPGSSIMPGKVN S323
fumarase (mouse) PENEPGSsIMPGKVN S363-p
fumarase (rat) PENEPGSSIMPGKVN S363
K447
ANTERINKLMNESLM
0 1
fumarase (human) ANTERINKLMNESLM K447
fumarase iso2 (human) ANTERINKLMNESLM K404
fumarase (mouse) ANTERINKLMNESLM K444
fumarase (rat) ANTERINkLMNESLM K444-ac
Y465-p
ALNPHIGyDkAAkIA
0 51
fumarase (human) ALNPHIGyDkAAkIA Y465-p
fumarase iso2 (human) ALNPHIGYDKAAKIA Y422
fumarase (mouse) ALNPHIGyDkAAkIA Y462-p
fumarase (rat) ALNPHIGyDKAAkIA Y462-p
K467-ac
NPHIGyDkAAkIAkT
0 2
fumarase (human) NPHIGyDkAAkIAkT K467-ac
fumarase iso2 (human) NPHIGYDKAAKIAKT K424
fumarase (mouse) NPHIGyDkAAkIAkT K464-ac
fumarase (rat) NPHIGyDKAAkIAkT K464
K470-ac
IGyDkAAkIAkTAHk
0 3
fumarase (human) IGyDkAAkIAkTAHk K470-ac
fumarase iso2 (human) IGYDKAAKIAKTAHK K427
fumarase (mouse) IGyDkAAkIAkTAHk K467-ac
fumarase (rat) IGyDKAAkIAkTAHK K467-ac
K473-ac
DkAAkIAkTAHkNGS
0 3
fumarase (human) DkAAkIAkTAHkNGS K473-ac
fumarase iso2 (human) DKAAKIAKTAHKNGS K430
fumarase (mouse) DkAAkIAkTAHkNGS K470-ac
fumarase (rat) DKAAkIAkTAHKNGS K470-ac
K477-ac
kIAkTAHkNGSTLKE
0 4
fumarase (human) kIAkTAHkNGSTLKE K477-ac
fumarase iso2 (human) KIAKTAHKNGSTLKE K434
fumarase (mouse) kIAkTAHkNGSTLKE K474-ac
fumarase (rat) kIAkTAHKNGSTLKK K474
Y491-p
ETAIELGyLtAEQFD
0 69
fumarase (human) ETAIELGyLtAEQFD Y491-p
fumarase iso2 (human) ETAIELGYLTAEQFD Y448
fumarase (mouse) ETAIELGyLtAEQFD Y488-p
fumarase (rat) KTAIELGYLTAEQFD Y488
T493-p
AIELGyLtAEQFDEW
0 2
fumarase (human) AIELGyLtAEQFDEW T493-p
fumarase iso2 (human) AIELGYLTAEQFDEW T450
fumarase (mouse) AIELGyLtAEQFDEW T490-p
fumarase (rat) AIELGYLTAEQFDEW T490
K502
EQFDEWVKPKDMLGP
0 2
fumarase (human) EQFDEWVKPKDMLGP K502
fumarase iso2 (human) EQFDEWVKPKDMLGP K459
fumarase (mouse) EQFDEWVkPkDMLGP K499-ac
fumarase (rat) EQFDEWVKPKDMLGP K499
K502-ub
EQFDEWVkPKDMLGP
0 1
fumarase (human) EQFDEWVkPKDMLGP K502-ub
fumarase iso2 (human) EQFDEWVKPKDMLGP K459
fumarase (mouse) EQFDEWVKPkDMLGP K499
fumarase (rat) EQFDEWVKPKDMLGP K499
K504
FDEWVkPKDMLGPK_
0 1
fumarase (human) FDEWVkPKDMLGPK_ K504
fumarase iso2 (human) FDEWVKPKDMLGPK_ K461
fumarase (mouse) FDEWVkPkDMLGPK_ K501-ac
fumarase (rat) FDEWVKPKDMLGPK_ K501