Other Species / Isoforms
  SMN (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

 HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
S4-p
____MAMssGGsGGG
Upstream
Downstream
2 14
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
Kinase, in vitro:
  • PKACA (human)
Putative in vivo kinases:
  • PKACA (human)
Treatment
  • KT5720
  • NKH_477
SMN (human) ____MAMssGGsGGG S4-p
SMN iso3 (human) ____MAMSSGGSGGG S4
SMN (mouse) ____MAMGsGGAGsE G4
SMN (rat) ____MAMGsGGGAGs G4
SMN (cow) gap -
S5-p
___MAMssGGsGGGV
Upstream
1 21
Kinase, in vitro:
  • PKACA (human)
Putative in vivo kinases:
  • PKACA (human)
Treatment
  • KT5720
  • NKH_477
SMN (human) ___MAMssGGsGGGV S5-p
SMN iso3 (human) ___MAMSSGGSGGGV S5
SMN (mouse) ___MAMGsGGAGsEQ S5-p
SMN (rat) ___MAMGsGGGAGsE S5-p
SMN (cow) gap -
S8-p
MAMssGGsGGGVPEQ
Upstream
1 17
Kinase, in vitro:
  • PKACA (human)
Putative in vivo kinases:
  • PKACA (human)
Treatment
  • KT5720
  • MG132_withdrawal
  • NKH_477
SMN (human) MAMssGGsGGGVPEQ S8-p
SMN iso3 (human) MAMSSGGSGGGVPEQ S8
SMN (mouse) MAMGsGGAGsEQEDt A8
SMN (rat) MAMGsGGGAGsEQED G8
SMN (cow) ____MGGGGGGFPEP G4
G10
MssGGsGGGVPEQED
0 16
SMN (human) MssGGsGGGVPEQED G10
SMN iso3 (human) MSSGGSGGGVPEQED G10
SMN (mouse) MGsGGAGsEQEDtVL S10-p
SMN (rat) MGsGGGAGsEQEDTV G10
SMN (cow) __MGGGGGGFPEPED G6
G11
ssGGsGGGVPEQEDs
0 1
SMN (human) ssGGsGGGVPEQEDs G11
SMN iso3 (human) SSGGSGGGVPEQEDS G11
SMN (mouse) gap -
SMN (rat) GsGGGAGsEQEDTVL S11-p
SMN (cow) _MGGGGGGFPEPEDS G7
S18-p
GVPEQEDsVLFRrGt
Downstream
1 4
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
SMN (human) GVPEQEDsVLFRrGt S18-p
SMN iso3 (human) GVPEQEDSVLFRRGT S18
SMN (mouse) AGsEQEDtVLFRRGt T15-p
SMN (rat) AGsEQEDTVLFRRGt T16
SMN (cow) GFPEPEDSVLFRRGT S14
R23-m1
EDsVLFRrGtGQsDD
0 1
SMN (human) EDsVLFRrGtGQsDD R23-m1
SMN iso3 (human) EDSVLFRRGTGQSDD R23
SMN (mouse) EDtVLFRRGtGQsDD R20
SMN (rat) EDTVLFRRGtGQsDD R21
SMN (cow) EDSVLFRRGTGESDD R19
T25-p
sVLFRrGtGQsDDsD
Upstream
Downstream
1 56
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
Treatment
  • BI2536
  • metastatic potential
SMN (human) sVLFRrGtGQsDDsD T25-p
SMN iso3 (human) SVLFRRGTGQSDDSD T25
SMN (mouse) tVLFRRGtGQsDDsD T22-p
SMN (rat) TVLFRRGtGQsDDsD T23-p
SMN (cow) SVLFRRGTGESDDSD T21
S28-p
FRrGtGQsDDsDIWD
Upstream
Downstream
3 104
Effects on Modified Protein
  • activity, induced
  • intracellular localization
  • molecular association, regulation
Treatment
  • BI_4834
  • metastatic potential
  • MG132_withdrawal
SMN (human) FRrGtGQsDDsDIWD S28-p
SMN iso3 (human) FRRGTGQSDDSDIWD S28
SMN (mouse) FRRGtGQsDDsDIWD S25-p
SMN (rat) FRRGtGQsDDsDIWD S26-p
SMN (cow) FRRGTGESDDSDVWD S24
S31-p
GtGQsDDsDIWDDtA
Upstream
Downstream
3 92
Effects on Modified Protein
  • activity, induced
  • intracellular localization
  • molecular association, regulation
Treatment
  • AZD1152
  • BI_4834
  • metastatic potential
  • nocodazole
  • ZM447439
SMN (human) GtGQsDDsDIWDDtA S31-p
SMN iso3 (human) GTGQSDDSDIWDDTA S31
SMN (mouse) GtGQsDDsDIWDDtA S28-p
SMN (rat) GtGQsDDsDIWDDtA S29-p
SMN (cow) GTGESDDSDVWDDTA S27
T37-p
DsDIWDDtALIkAyD
0 3
SMN (human) DsDIWDDtALIkAyD T37-p
SMN iso3 (human) DSDIWDDTALIKAYD T37
SMN (mouse) DsDIWDDtALIKAYD T34-p
SMN (rat) DsDIWDDtALIKAYD T35-p
SMN (cow) DSDVWDDTALIKAYD T33
K41-ub
WDDtALIkAyDkAVA
0 4
SMN (human) WDDtALIkAyDkAVA K41-ub
SMN iso3 (human) WDDTALIKAYDKAVA K41
SMN (mouse) WDDtALIKAYDKAVA K38
SMN (rat) WDDtALIKAYDKAVA K39
SMN (cow) WDDTALIKAYDKAVA K37
Y43-p
DtALIkAyDkAVAsF
0 10
SMN (human) DtALIkAyDkAVAsF Y43-p
SMN iso3 (human) DTALIKAYDKAVASF Y43
SMN (mouse) DtALIKAYDKAVASF Y40
SMN (rat) DtALIKAYDKAVASF Y41
SMN (cow) DTALIKAYDKAVASF Y39
K45-ac
ALIkAyDkAVAsFkH
0 2
SMN (human) ALIkAyDkAVAsFkH K45-ac
SMN iso3 (human) ALIKAYDKAVASFKH K45
SMN (mouse) ALIKAYDKAVASFKH K42
SMN (rat) ALIKAYDKAVASFKH K43
SMN (cow) ALIKAYDKAVASFKH K41
K45-ub
ALIkAyDkAVAsFkH
0 3
SMN (human) ALIkAyDkAVAsFkH K45-ub
SMN iso3 (human) ALIKAYDKAVASFKH K45
SMN (mouse) ALIKAYDKAVASFKH K42
SMN (rat) ALIKAYDKAVASFKH K43
SMN (cow) ALIKAYDKAVASFKH K41
S49-p
AyDkAVAsFkHALkN
Upstream
Downstream
1 1
Effects on Modified Protein
  • molecular association, regulation
  • protein conformation
Effects on Biological Processes:
  • cell growth, induced
Kinase, in vitro:
  • p70S6K (human)
Putative in vivo kinases:
  • p70S6K (human)
Treatment
  • amino_acid_starvation
  • serum_starvation
  • Torin1
SMN (human) AyDkAVAsFkHALkN S49-p
SMN iso3 (human) AYDKAVASFKHALKN S49
SMN (mouse) AYDKAVASFKHALKN S46
SMN (rat) AYDKAVASFKHALKN S47
SMN (cow) AYDKAVASFKHALKN S45
K51-ub
DkAVAsFkHALkNGD
0 3
SMN (human) DkAVAsFkHALkNGD K51-ub
SMN iso3 (human) DKAVASFKHALKNGD K51
SMN (mouse) DKAVASFKHALKNGD K48
SMN (rat) DKAVASFKHALKNGD K49
SMN (cow) DKAVASFKHALKNGD K47
K51-m1
DkAVAsFkHALkNGD
0 1
SMN (human) DkAVAsFkHALkNGD K51-m1
SMN iso3 (human) DKAVASFKHALKNGD K51
SMN (mouse) DKAVASFKHALKNGD K48
SMN (rat) DKAVASFKHALKNGD K49
SMN (cow) DKAVASFKHALKNGD K47
K55-m1
AsFkHALkNGDICET
0 1
SMN (human) AsFkHALkNGDICET K55-m1
SMN iso3 (human) ASFKHALKNGDICET K55
SMN (mouse) ASFKHALKNGDICEt K52
SMN (rat) ASFKHALKNGDMCET K53
SMN (cow) ASFKHALKNGDISEA K51
K55-ub
AsFkHALkNGDICET
0 1
SMN (human) AsFkHALkNGDICET K55-ub
SMN iso3 (human) ASFKHALKNGDICET K55
SMN (mouse) ASFKHALKNGDICEt K52
SMN (rat) ASFKHALKNGDMCET K53
SMN (cow) ASFKHALKNGDISEA K51
T62
kNGDICETsGkPKtt
0 5
SMN (human) kNGDICETsGkPKtt T62
SMN iso3 (human) KNGDICETSGKPKTT T62
SMN (mouse) KNGDICEtPDKPKGT T59-p
SMN (rat) KNGDMCETSDKPKGT T60
SMN (cow) KNGDISEASEKPKGT A58
S63-p
NGDICETsGkPKttP
Upstream
Downstream
1 2
Effects on Modified Protein
  • molecular association, regulation
  • protein conformation
Effects on Biological Processes:
  • cell growth, induced
Regulatory protein:
  • p70S6K (human)
SMN (human) NGDICETsGkPKttP S63-p
SMN iso3 (human) NGDICETSGKPKTTP S63
SMN (mouse) NGDICEtPDKPKGTA P60
SMN (rat) NGDMCETSDKPKGTA S61
SMN (cow) NGDISEASEKPKGTP S59
K65-ac
DICETsGkPKttPKR
0 1
SMN (human) DICETsGkPKttPKR K65-ac
SMN iso3 (human) DICETSGKPKTTPKR K65
SMN (mouse) DICEtPDKPKGTARR K62
SMN (rat) DMCETSDKPKGTARR K63
SMN (cow) DISEASEKPKGTPKR K61
T68-p
ETsGkPKttPKRKPA
Downstream
1 2
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
SMN (human) ETsGkPKttPKRKPA T68-p
SMN iso3 (human) ETSGKPKTTPKRKPA T68
SMN (mouse) EtPDKPKGTARRKPA G65
SMN (rat) ETSDKPKGTARRKPA G66
SMN (cow) EASEKPKGTPKRKSA G64
T69-p
TsGkPKttPKRKPAK
0 4
SMN (human) TsGkPKttPKRKPAK T69-p
SMN iso3 (human) TSGKPKTTPKRKPAK T69
SMN (mouse) tPDKPKGTARRKPAK T66
SMN (rat) TSDKPKGTARRKPAK T67
SMN (cow) ASEKPKGTPKRKSAK T65
S80-p
KPAKKNKsQKkNtAA
0 1
SMN (human) KPAKKNKsQKkNtAA S80-p
SMN iso3 (human) KPAKKNKSQKKNTAA S80
SMN (mouse) KPAKKNKSQKKNATT S77
SMN (rat) KPAKKNKNQKKNATA N78
SMN (cow) RKSAKNKSQRKNTtS S75
K83-ub
KKNKsQKkNtAAsLQ
0 2
SMN (human) KKNKsQKkNtAAsLQ K83-ub
SMN iso3 (human) KKNKSQKKNTAASLQ K83
SMN (mouse) KKNKSQKKNATTPLK K80
SMN (rat) KKNKNQKKNATAPLK K81
SMN (cow) AKNKSQRKNTtSPSK K78
T85-p
NKsQKkNtAAsLQQW
Upstream
Downstream
2 5
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
Kinase, in vitro:
  • PKACA (human)
SMN (human) NKsQKkNtAAsLQQW T85-p
SMN iso3 (human) NKSQKKNTAASLQQW T85
SMN (mouse) NKSQKKNATTPLKQW A82
SMN (rat) NKNQKKNATAPLKQW A83
SMN (cow) NKSQRKNTtSPSKQW T80
A86
KsQKkNtAAsLQQWk
0 1
SMN (human) KsQKkNtAAsLQQWk A86
SMN iso3 (human) KSQKKNTAASLQQWK A86
SMN (mouse) KSQKKNATTPLKQWK T83
SMN (rat) KNQKKNATAPLKQWK T84
SMN (cow) KSQRKNTtSPSKQWK T81-p
S88-p
QKkNtAAsLQQWkVG
Downstream
1 4
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
SMN (human) QKkNtAAsLQQWkVG S88-p
SMN iso3 (human) QKKNTAASLQQWKVG S88
SMN (mouse) QKKNATTPLKQWKVG P85
SMN (rat) QKKNATAPLKQWKAG P86
SMN (cow) QRKNTtSPSKQWKVG P83
K93-ub
AAsLQQWkVGDKCSA
0 1
SMN (human) AAsLQQWkVGDKCSA K93-ub
SMN iso3 (human) AASLQQWKVGDKCSA K93
SMN (mouse) TTPLKQWKVGDKCSA K90
SMN (rat) TAPLKQWKAGDKCSA K91
SMN (cow) tSPSKQWKVGDNCCA K88
Y109-p
WSEDGCIyPATIASI
Downstream
1 1
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
SMN (human) WSEDGCIyPATIASI Y109-p
SMN iso3 (human) WSEDGCIYPATIASI Y109
SMN (mouse) WSEDGCIYPATITSI Y106
SMN (rat) WSEDGCVYPATITSV Y107
SMN (cow) WSEDGCIYPATIASI Y104
K119-ac
TIASIDFkRETCVVV
0 3
SMN (human) TIASIDFkRETCVVV K119-ac
SMN iso3 (human) TIASIDFKRETCVVV K119
SMN (mouse) TITSIDFKRETCVVV K116
SMN (rat) TITSVDLKRETCVVV K117
SMN (cow) TIASIDFKRETCVVV K114
Y127-p
RETCVVVyTGyGNRE
Downstream
1 1
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
SMN (human) RETCVVVyTGyGNRE Y127-p
SMN iso3 (human) RETCVVVYTGYGNRE Y127
SMN (mouse) RETCVVVYTGYGNRE Y124
SMN (rat) RETCVVVYTGYGNKE Y125
SMN (cow) RETCVVVYTGYGNRE Y122
Y130-p
CVVVyTGyGNREEQN
Downstream
1 1
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
SMN (human) CVVVyTGyGNREEQN Y130-p
SMN iso3 (human) CVVVYTGYGNREEQN Y130
SMN (mouse) CVVVYTGYGNREEQN Y127
SMN (rat) CVVVYTGYGNKEEQN Y128
SMN (cow) CVVVYTGYGNREEQN Y125
S166-p
NENESQVsTDESENS
0 1
SMN (human) NENESQVsTDESENS S166-p
SMN iso3 (human) NENESQVSTDESENS S166
SMN (mouse) QENESQVSTDDSEHS S161
SMN (rat) QENESQVSTDDSEHS S162
SMN (cow) NENESQISTDESENS S160
S175-p
DESENSRsPGNksDN
0 1
SMN (human) DESENSRsPGNksDN S175-p
SMN iso3 (human) DESENSRSPGNKSDN S175
SMN (mouse) DDSEHSSRSLRSKAH R170
SMN (rat) DDSEHSSRSLRSKAH R171
SMN (cow) ESENSSRSPLNKPNN S170
K179-ub
NSRsPGNksDNIkPk
0 2
SMN (human) NSRsPGNksDNIkPk K179-ub
SMN iso3 (human) NSRSPGNKSDNIKPK K179
SMN (mouse) HSSRSLRSKAHSKSK S174
SMN (rat) HSSRSLRSKAHSKSK S175
SMN (cow) SSRSPLNKPNNIRSR K174
S180-p
SRsPGNksDNIkPks
Downstream
1 4
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
SMN (human) SRsPGNksDNIkPks S180-p
SMN iso3 (human) SRSPGNKSDNIKPKS S180
SMN (mouse) SSRSLRSKAHSKSKA K175
SMN (rat) SSRSLRSKAHSKSKA K176
SMN (cow) SRSPLNKPNNIRSRA P175
K184-ub
GNksDNIkPksAPWN
0 1
SMN (human) GNksDNIkPksAPWN K184-ub
SMN iso3 (human) GNKSDNIKPKSAPWN K184
SMN (mouse) LRSKAHSKSKAAPWT K179
SMN (rat) LRSKAHSKSKAAPWT K180
SMN (cow) LNKPNNIRSRAAPWN R179
K186-ub
ksDNIkPksAPWNsF
0 1
SMN (human) ksDNIkPksAPWNsF K186-ub
SMN iso3 (human) KSDNIKPKSAPWNSF K186
SMN (mouse) SKAHSKSKAAPWTSF K181
SMN (rat) SKAHSKSKAAPWTSF K182
SMN (cow) KPNNIRSRAAPWNSF R181
S187-p
sDNIkPksAPWNsFL
Upstream
Downstream
1 5
Effects on Modified Protein
  • molecular association, regulation
Kinase, in vitro:
  • PKACA (human)
Treatment
  • ischemia
SMN (human) sDNIkPksAPWNsFL S187-p
SMN iso3 (human) SDNIKPKSAPWNSFL S187
SMN (mouse) KAHSKSKAAPWTSFL A182
SMN (rat) KAHSKSKAAPWTSFL A183
SMN (cow) PNNIRSRAAPWNSFL A182
S192-p
PksAPWNsFLPPPPP
0 1
SMN (human) PksAPWNsFLPPPPP S192-p
SMN iso3 (human) PKSAPWNSFLPPPPP S192
SMN (mouse) SKAAPWTSFLPPPPP S187
SMN (rat) SKAAPWTSFLPPPPP S188
SMN (cow) SRAAPWNSFLPPPPH S187
R204-m1
PPPMPGPrLGPGkPG
0 4
SMN (human) PPPMPGPrLGPGkPG R204-m1
SMN iso3 (human) PPPMPGPRLGPGKPG R204
SMN (mouse) PPPMPGSGLGPGkPG G199
SMN (rat) PPPVPGAGLGPGKPG G200
SMN (cow) PPHMPRSGLGPGKSG G199
K209-ub
GPrLGPGkPGLKFNG
0 11
SMN (human) GPrLGPGkPGLKFNG K209-ub
SMN iso3 (human) GPRLGPGKPGLKFNG K209
SMN (mouse) GSGLGPGkPGLKFNG K204-ub
SMN (rat) GAGLGPGKPGLrFSG K205
SMN (cow) RSGLGPGKSGLNFSG K204
K213
GPGkPGLKFNGPPPP
0 3
SMN (human) GPGkPGLKFNGPPPP K213
SMN iso3 (human) GPGKPGLKFNGPPPP K213
SMN (mouse) GPGkPGLKFNGPPPP K208
SMN (rat) GPGKPGLrFSGPPPP R209-m1
SMN (cow) GPGKSGLNFSGPPPP N208