Other Species / Isoforms
  DYRK2 (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

  HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
S7-p
_MLTRKPsAAAPAAY
0 1
DYRK2 (human) _MLTRKPsAAAPAAY S7-p
DYRK2 iso2 (human) gap -
DYRK2 (mouse) _MLTRKPSAAAPAAY S7
DYRK2 (rat) gap -
R18-m1
PAAYPTGrGGDSAVR
0 2
DYRK2 (human) PAAYPTGrGGDSAVR R18-m1
DYRK2 iso2 (human) gap -
DYRK2 (mouse) PAAYPTGRGGDTAVR R18
DYRK2 (rat) gap -
S30-p
AVRQLQAsPGLGAGA
0 14
DYRK2 (human) AVRQLQAsPGLGAGA S30-p
DYRK2 iso2 (human) gap -
DYRK2 (mouse) AVRQLQAsPGIGAGA S30-p
DYRK2 (rat) gap -
T44-p
ATRSGVGtGPPsPIA
0 1
DYRK2 (human) ATRSGVGtGPPsPIA T44-p
DYRK2 iso2 (human) gap -
DYRK2 (mouse) APRSGVGTGPPsPIA T44
DYRK2 (rat) gap -
S48-p
GVGtGPPsPIALPPL
0 8
DYRK2 (human) GVGtGPPsPIALPPL S48-p
DYRK2 iso2 (human) gap -
DYRK2 (mouse) GVGTGPPsPIALPPL S48-p
DYRK2 (rat) gap -
T105
SNKRTVLTtQPNGLT
1 1
DYRK2 (human) SNKRTVLTtQPNGLT T105
DYRK2 iso2 (human) SNKRTVLttQPNGLT T32-p
DYRK2 (mouse) SNKRTVLTTQPNGLT T103
DYRK2 (rat) SNKRTVLTTQPNGLT T31
T106-p
NKRTVLTtQPNGLTT
Upstream
Downstream
2 1
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
  • protein stabilization
Putative in vivo kinases:
  • ATM (human)
Treatment
  • adriamycin
DYRK2 (human) NKRTVLTtQPNGLTT T106-p
DYRK2 iso2 (human) NKRTVLttQPNGLTT T33-p
DYRK2 (mouse) NKRTVLTTQPNGLTT T104
DYRK2 (rat) NKRTVLTTQPNGLTT T32
S142-p
GSSTSLKsMEGMGKV
0 1
DYRK2 (human) GSSTSLKsMEGMGKV S142-p
DYRK2 iso2 (human) GSSTSLKSMEGMGKV S69
DYRK2 (mouse) GSSTSLKSMEGMGKV S140
DYRK2 (rat) GSSTSLKSMEGMGKV S68
T155
KVKATPMTPEQAMKQ
1 1
DYRK2 (human) KVKATPMTPEQAMKQ T155
DYRK2 iso2 (human) KVKATPMtPEQAMKQ T82-p
DYRK2 (mouse) KVKASPMTPEQAMKQ T153
DYRK2 (rat) KVKASPMTPEQAMKQ T81
Y380-p
CYEHQRVytyIQSRF
0 2
DYRK2 (human) CYEHQRVytyIQSRF Y380-p
DYRK2 iso2 (human) CYEHQRVYTyIQSRF Y307
DYRK2 (mouse) CYEHQRVYtyIQSRF Y378
DYRK2 (rat) CYEHQRVYTyIQSRF Y306
T381-p
YEHQRVytyIQSRFY
Upstream
1 12
Kinase, in vitro:
  • MLK2 (human)
DYRK2 (human) YEHQRVytyIQSRFY T381-p
DYRK2 iso2 (human) YEHQRVYTyIQSRFY T308
DYRK2 (mouse) YEHQRVYtyIQSRFY T379-p
DYRK2 (rat) YEHQRVYTyIQSRFy T307
Y382-p
EHQRVytyIQSRFYR
Upstream
1 1689
Regulatory protein:
  • EGFR (human)
  • FGFR1 (human)
Treatment
  • FGF2
  • U0126
DYRK2 (human) EHQRVytyIQSRFYR Y382-p
DYRK2 iso2 (human) EHQRVYTyIQSRFYR Y309-p
DYRK2 (mouse) EHQRVYtyIQSRFYR Y380-p
DYRK2 (rat) EHQRVYTyIQSRFyR Y308-p
Y388
tyIQSRFYRAPEVIL
0 2
DYRK2 (human) tyIQSRFYRAPEVIL Y388
DYRK2 iso2 (human) TyIQSRFYRAPEVIL Y315
DYRK2 (mouse) tyIQSRFYRAPEVIL Y386
DYRK2 (rat) TyIQSRFyRAPEVIL Y314-p
S442-p
IELLGMPsQKLLDAs
Upstream
Downstream
1 0
Effects on Modified Protein
  • enzymatic activity, induced
Effects on Biological Processes:
  • apoptosis, altered
Putative in vivo kinases:
  • ATM (human)
Treatment
  • adriamycin
DYRK2 (human) IELLGMPsQKLLDAs S442-p
DYRK2 iso2 (human) IELLGMPSQKLLDAS S369
DYRK2 (mouse) IELLGMPSQKLLDAS S440
DYRK2 (rat) IELLGMPSQKLLDAS S368
S449-p
sQKLLDAsKRAKNFV
Upstream
1 0
Kinase, in vitro:
  • MLK2 (human)
DYRK2 (human) sQKLLDAsKRAKNFV S449-p
DYRK2 iso2 (human) SQKLLDASKRAKNFV S376
DYRK2 (mouse) SQKLLDASKRAKNFV S447
DYRK2 (rat) SQKLLDASKRAKNFV S375
Y464-p
SSKGYPRyCTVTTLS
0 1
DYRK2 (human) SSKGYPRyCTVTTLS Y464-p
DYRK2 iso2 (human) SSKGYPRYCTVTTLS Y391
DYRK2 (mouse) SSKGYPRYCTVTTLS Y462
DYRK2 (rat) SSKGYPRYCTVTTLS Y390
T525-p
WDPAVRMtPGQALRH
0 1
DYRK2 (human) WDPAVRMtPGQALRH T525-p
DYRK2 iso2 (human) WDPAVRMTPGQALRH T452
DYRK2 (mouse) WDPAVRMTPGQALRH T523
DYRK2 (rat) WDPAVRMTPGQALRH T451
S556
SVKRITESTGAITSI
1 1
DYRK2 (human) SVKRITESTGAITSI S556
DYRK2 iso2 (human) SVKRITEstGAItsI S483-p
DYRK2 (mouse) AVKRVTESTGAITSI S554
DYRK2 (rat) AVKRVTESTGAITSI S482
T557
VKRITESTGAITSIS
1 1
DYRK2 (human) VKRITESTGAITSIS T557
DYRK2 iso2 (human) VKRITEstGAItsIS T484-p
DYRK2 (mouse) VKRVTESTGAITSIS T555
DYRK2 (rat) VKRVTESTGAITSIS T483
T561
TESTGAITSISKLPP
1 1
DYRK2 (human) TESTGAITSISKLPP T561
DYRK2 iso2 (human) TEstGAItsISKLPP T488-p
DYRK2 (mouse) TESTGAITSISKLPP T559
DYRK2 (rat) TESTGAITSISKLPP T487
S562
ESTGAITSISKLPPP
1 1
DYRK2 (human) ESTGAITSISKLPPP S562
DYRK2 iso2 (human) EstGAItsISKLPPP S489-p
DYRK2 (mouse) ESTGAITSISKLPPP S560
DYRK2 (rat) ESTGAITSISKLPPP S488
S570
ISKLPPPSSSASKLR
1 1
DYRK2 (human) ISKLPPPSSSASKLR S570
DYRK2 iso2 (human) ISKLPPPsssAsKLR S497-p
DYRK2 (mouse) ISKLPPPSSSASKLR S568
DYRK2 (rat) ISKLPPPSSSASKLR S496
S571
SKLPPPSSSASKLRT
1 1
DYRK2 (human) SKLPPPSSSASKLRT S571
DYRK2 iso2 (human) SKLPPPsssAsKLRT S498-p
DYRK2 (mouse) SKLPPPSSSASKLRT S569
DYRK2 (rat) SKLPPPSSSASKLRT S497
S572
KLPPPSSSASKLRTN
1 1
DYRK2 (human) KLPPPSSSASKLRTN S572
DYRK2 iso2 (human) KLPPPsssAsKLRTN S499-p
DYRK2 (mouse) KLPPPSSSASKLRTN S570
DYRK2 (rat) KLPPPSSSASKLRTN S498
S574
PPPSSSASKLRTNLA
1 1
DYRK2 (human) PPPSSSASKLRTNLA S574
DYRK2 iso2 (human) PPPsssAsKLRTNLA S501-p
DYRK2 (mouse) PPPSSSASKLRTNLA S572
DYRK2 (rat) PPPSSSASKLRTNLA S500