Other Species / Isoforms
  LRP6 (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

 HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
S171-p
ERAGMDGssRFIIIN
0 1
LRP6 (human) ERAGMDGssRFIIIN S171-p
LRP6 (mouse) ERAGMDGSSRFVIIN S171
LRP6 (rat) ERAGMDGSSRFVIIN S20
S172-p
RAGMDGssRFIIINS
0 1
LRP6 (human) RAGMDGssRFIIINS S172-p
LRP6 (mouse) RAGMDGSSRFVIINT S172
LRP6 (rat) RAGMDGSSRFVIINT S21
S209-p
KLNFIHKsNLDGtNR
0 1
LRP6 (human) KLNFIHKsNLDGtNR S209-p
LRP6 (mouse) KLNFIHKSNLDGTNR S209
LRP6 (rat) KLNFIHKSNLDGTNR S58
T214-p
HKsNLDGtNRQAVVK
0 1
LRP6 (human) HKsNLDGtNRQAVVK T214-p
LRP6 (mouse) HKSNLDGTNRQAVVK T214
LRP6 (rat) HKSNLDGTNRQAVVK T63
K733-ub
TNRIEVSkLDGQHRQ
0 1
LRP6 (human) TNRIEVSkLDGQHRQ K733-ub
LRP6 (mouse) TNRIEVSKLDGQHRQ K733
LRP6 (rat) TNRIEVSKLDGQHRQ K582
K802-ac
GLTIDYAkRRLYWTD
0 1
LRP6 (human) GLTIDYAkRRLYWTD K802-ac
LRP6 (mouse) GLTIDYAKRRLYWTD K802
LRP6 (rat) GLTIDYAKRRLYWTD K651
K941-ub
TFLLFSQkSAINRMV
0 1
LRP6 (human) TFLLFSQkSAINRMV K941-ub
LRP6 (mouse) TFLLFSQKSAINRMV K941
LRP6 (rat) TFLLFSQKSAINRMV K790
K977-ub
IDYDPLDkQLYWIDS
0 2
LRP6 (human) IDYDPLDkQLYWIDS K977-ub
LRP6 (mouse) IDYDPLDKQLYWIDS K977
LRP6 (rat) IDYDPLDKQLYWIDS K826
T1001-p
EDGSQGFtVVVSSVP
0 1
LRP6 (human) EDGSQGFtVVVSSVP T1001-p
LRP6 (mouse) EDGGQGFNVVANSVA N1001
LRP6 (rat) EDGGQGFTVVVSSVP T850
K1195-ub
LSDIHAVkELNLQEY
0 1
LRP6 (human) LSDIHAVkELNLQEY K1195-ub
LRP6 (mouse) LSDIHAVKELNLQEY K1195
LRP6 (rat) LSDIHAVKELNLQEY K1044
S1420-p
YVVHGPAsVPLGYVP
Upstream
Downstream
1 0
Effects on Modified Protein
  • molecular association, regulation
Kinase, in vitro:
  • CK1E (human)
LRP6 (human) YVVHGPAsVPLGYVP S1420-p
LRP6 (mouse) YVVHSPASVPLGYVP S1420
LRP6 (rat) gap -
S1431-p
GYVPHPSsLSGSLPG
Upstream
Downstream
1 0
Effects on Modified Protein
  • molecular association, regulation
Kinase, in vitro:
  • CK1E (human)
LRP6 (human) GYVPHPSsLSGSLPG S1431-p
LRP6 (mouse) GYVPHPSSLSGSLPG S1431
LRP6 (rat) gap -
K1443-ub
LPGMSRGksMISSLS
0 1
LRP6 (human) LPGMSRGksMISSLS K1443-ub
LRP6 (mouse) LPGMSRGKsMISSLS K1443
LRP6 (rat) gap -
S1444-p
PGMSRGksMISSLSI
0 1
LRP6 (human) PGMSRGksMISSLSI S1444-p
LRP6 (mouse) PGMSRGKsMISSLSI S1444-p
LRP6 (rat) gap -
S1455-p
SLSIMGGsSGPPyDR
0 1
LRP6 (human) SLSIMGGsSGPPyDR S1455-p
LRP6 (mouse) SLSIMGGSSGPPYDR S1455
LRP6 (rat) gap -
Y1460-p
GGsSGPPyDRAHVTG
0 4
LRP6 (human) GGsSGPPyDRAHVTG Y1460-p
LRP6 (mouse) GGSSGPPYDRAHVTG Y1460
LRP6 (rat) gap -
S1474-p
GASSSSSsstKGtyF
0 1
LRP6 (human) GASSSSSsstKGtyF S1474-p
LRP6 (mouse) GASSSSSSSTKGTYF S1474
LRP6 (rat) gap -
S1475-p
ASSSSSsstKGtyFP
0 1
LRP6 (human) ASSSSSsstKGtyFP S1475-p
LRP6 (mouse) ASSSSSSSTKGTYFP S1475
LRP6 (rat) gap -
T1476-p
SSSSSsstKGtyFPA
0 2
LRP6 (human) SSSSSsstKGtyFPA T1476-p
LRP6 (mouse) SSSSSSSTKGTYFPA T1476
LRP6 (rat) gap -
T1479-p
SSsstKGtyFPAILN
Upstream
Downstream
6 2
Effects on Modified Protein
  • activity, induced
  • molecular association, regulation
Kinase, in vitro:
  • CK1G1 (human)
Putative in vivo kinases:
  • CK1G1 (human)
Regulatory protein:
  • LRP6 (human)
  • WTX (human)
Treatment
  • PI(4,5)P2
  • TPO
  • Wnt
  • Wnt3a
LRP6 (human) SSsstKGtyFPAILN T1479-p
LRP6 (mouse) SSSSTKGTYFPAILN T1479
LRP6 (rat) gap -
Y1480-p
SsstKGtyFPAILNP
0 1
LRP6 (human) SsstKGtyFPAILNP Y1480-p
LRP6 (mouse) SSSTKGTYFPAILNP Y1480
LRP6 (rat) gap -
S1490-p
AILNPPPsPAtERsH
Upstream
Downstream
20 67
LRP6 (human)
S1490-p
LRP6 (mouse)
S1490-p
Effects on Modified Protein
  • activity, induced
  • molecular association, regulation
  • phosphorylation
Effects on Biological Processes:
  • cell cycle regulation
  • signaling pathway regulation
  • transcription, altered
  • transcription, induced
Kinase, in vitro:
  • ERK1 (human)
  • GSK3B (human)
Putative in vivo kinases:
  • CDK14 (human)
  • ERK1 (human)
  • GSK3B (human)
Regulatory protein:
  • BRAF (human)
  • C1QDC1 (human)
  • caveolin-1 (human)
  • CBCP1 (human)
  • CD44 (human)
  • CDK14 (human)
  • DVL1 (human)
  • FZD2 (human)
  • FZD4 (human)
  • FZD5 (human)
  • KRas (human)
  • LRP6 (human)
  • PI4K2A (human)
  • PIP5K1A (human)
  • PIP5K1B (human)
  • WNT3 (human)
  • WNT3A (human)
  • WNT9B (human)
  • WTX (human)
Treatment
  • 4-HT
  • CTGF
  • FGF2
  • IFN-gamma
  • ionomycin
  • lithium
  • PD184352
  • PI(4,5)P2
  • SB216763
  • SCH772984
  • siRNA
  • SP600125
  • SU5402
  • TNF
  • TPO
  • tunicamycin
  • U0126
  • Wnt3a
LRP6 (human) AILNPPPsPAtERsH S1490-p
LRP6 (mouse) AILNPPPsPAtERSH S1490-p
LRP6 (rat) gap -
T1493-p
NPPPsPAtERsHytM
Upstream
3 10
Kinase, in vitro:
  • CK1A (human)
Putative in vivo kinases:
  • CK1A (human)
Regulatory protein:
  • WNT3A (human)
Treatment
  • TPO
LRP6 (human) NPPPsPAtERsHytM T1493-p
LRP6 (mouse) NPPPsPAtERSHYTM T1493-p
LRP6 (rat) gap -
S1496-p
PsPAtERsHytMEFG
0 1
LRP6 (human) PsPAtERsHytMEFG S1496-p
LRP6 (mouse) PsPAtERSHYTMEFG S1496
LRP6 (rat) gap -
Y1498-p
PAtERsHytMEFGyS
0 21
LRP6 (human) PAtERsHytMEFGyS Y1498-p
LRP6 (mouse) PAtERSHYTMEFGYS Y1498
LRP6 (rat) gap -
T1499-p
AtERsHytMEFGySs
0 1
LRP6 (human) AtERsHytMEFGySs T1499-p
LRP6 (mouse) AtERSHYTMEFGYSS T1499
LRP6 (rat) gap -
Y1504-p
HytMEFGySsNsPsT
0 6
LRP6 (human) HytMEFGySsNsPsT Y1504-p
LRP6 (mouse) HYTMEFGYSSNsPST Y1504
LRP6 (rat) gap -
S1506-p
tMEFGySsNsPsTHR
0 1
LRP6 (human) tMEFGySsNsPsTHR S1506-p
LRP6 (mouse) TMEFGYSSNsPSTHR S1506
LRP6 (rat) gap -
S1508-p
EFGySsNsPsTHRSy
0 8
LRP6 (human) EFGySsNsPsTHRSy S1508-p
LRP6 (mouse) EFGYSSNsPSTHRSY S1508-p
LRP6 (rat) gap -
S1510-p
GySsNsPsTHRSysy
0 1
LRP6 (human) GySsNsPsTHRSysy S1510-p
LRP6 (mouse) GYSSNsPSTHRSYSY S1510
LRP6 (rat) gap -
Y1515-p
sPsTHRSysyrPysy
0 3
LRP6 (human) sPsTHRSysyrPysy Y1515-p
LRP6 (mouse) sPSTHRSYSYRPYSY Y1515
LRP6 (rat) gap -
S1516-p
PsTHRSysyrPysyR
0 2
LRP6 (human) PsTHRSysyrPysyR S1516-p
LRP6 (mouse) PSTHRSYSYRPYSYR S1516
LRP6 (rat) gap -
Y1517-p
sTHRSysyrPysyRH
0 2
LRP6 (human) sTHRSysyrPysyRH Y1517-p
LRP6 (mouse) STHRSYSYRPYSYRH Y1517
LRP6 (rat) gap -
R1518-m1
THRSysyrPysyRHF
0 4
LRP6 (human) THRSysyrPysyRHF R1518-m1
LRP6 (mouse) THRSYSYRPYSYRHF R1518
LRP6 (rat) gap -
Y1520-p
RSysyrPysyRHFAP
0 10
LRP6 (human) RSysyrPysyRHFAP Y1520-p
LRP6 (mouse) RSYSYRPYSYRHFAP Y1520
LRP6 (rat) gap -
S1521-p
SysyrPysyRHFAPP
0 1
LRP6 (human) SysyrPysyRHFAPP S1521-p
LRP6 (mouse) SYSYRPYSYRHFAPP S1521
LRP6 (rat) gap -
Y1522-p
ysyrPysyRHFAPPT
0 14
LRP6 (human) ysyrPysyRHFAPPT Y1522-p
LRP6 (mouse) YSYRPYSYRHFAPPT Y1522
LRP6 (rat) gap -
Y1541-p
TDVCDSDyAPsRRMt
Upstream
0 62
Treatment
  • ephrin_B1
  • Su11274
LRP6 (human) TDVCDSDyAPsRRMt Y1541-p
LRP6 (mouse) TDVCDSDyAPSRRMT Y1541-p
LRP6 (rat) gap -
S1544-p
CDSDyAPsRRMtSVA
Upstream
1 1
Kinase, in vitro:
  • GSK3A (human)
LRP6 (human) CDSDyAPsRRMtSVA S1544-p
LRP6 (mouse) CDSDyAPSRRMTSVA S1544
LRP6 (rat) gap -
T1548-p
yAPsRRMtSVATAkG
Upstream
Downstream
1 0
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
Kinase, in vitro:
  • PKACA (human)
LRP6 (human) yAPsRRMtSVATAkG T1548-p
LRP6 (mouse) yAPSRRMTSVATAKG T1548
LRP6 (rat) gap -
K1554-ub
MtSVATAkGYTSDLN
0 2
LRP6 (human) MtSVATAkGYTSDLN K1554-ub
LRP6 (mouse) MTSVATAKGYTSDVN K1554
LRP6 (rat) gap -
Y1562-p
GYTSDLNyDSEPVPP
Upstream
0 9
Treatment
  • ephrin_B1
LRP6 (human) GYTSDLNyDSEPVPP Y1562-p
LRP6 (mouse) GYTSDVNYDSEPVPP Y1562
LRP6 (rat) gap -
T1572-p
EPVPPPPtPRsQyLs
Upstream
Downstream
4 8
Effects on Modified Protein
  • activity, induced
Effects on Biological Processes:
  • signaling pathway regulation
  • transcription, induced
Putative in vivo kinases:
  • ERK1 (human)
Regulatory protein:
  • BRAF (human)
  • FGFR2 (human)
  • FGFR3 (human)
  • KRas (human)
Treatment
  • 4-HT
  • FGF2
  • PD184352
  • SB216763
  • SCH772984
  • SP600125
  • SU5402
  • U0126
LRP6 (human) EPVPPPPtPRsQyLs T1572-p
LRP6 (mouse) EPVPPPPtPRSQYLs T1572-p
LRP6 (rat) gap -
S1575-p
PPPPtPRsQyLsAEE
0 1
LRP6 (human) PPPPtPRsQyLsAEE S1575-p
LRP6 (mouse) PPPPtPRSQYLsAEE S1575
LRP6 (rat) gap -
Y1577-p
PPtPRsQyLsAEENy
Upstream
0 4
Treatment
  • Su11274
LRP6 (human) PPtPRsQyLsAEENy Y1577-p
LRP6 (mouse) PPtPRSQYLsAEENY Y1577
LRP6 (rat) gap -
S1579-p
tPRsQyLsAEENyES
1 1
LRP6 (human) tPRsQyLsAEENyES S1579-p
LRP6 (mouse) tPRSQYLsAEENYES S1579-p
LRP6 (rat) gap -
Y1584-p
yLsAEENyESCPPsP
0 12
LRP6 (human) yLsAEENyESCPPsP Y1584-p
LRP6 (mouse) YLsAEENYESCPPsP Y1584
LRP6 (rat) gap -
S1590-p
NyESCPPsPYTERSY
0 3
LRP6 (human) NyESCPPsPYTERSY S1590-p
LRP6 (mouse) NYESCPPsPYTERSY S1590-p
LRP6 (rat) gap -
S1607-p
HLYPPPPsPCTDss_
2 1
LRP6 (human) HLYPPPPsPCTDss_ S1607-p
LRP6 (mouse) HLYPPPPsPCTDSS_ S1607-p
LRP6 (rat) gap -
S1612-p
PPsPCTDss______
0 4
LRP6 (human) PPsPCTDss______ S1612-p
LRP6 (mouse) PPsPCTDSS______ S1612
LRP6 (rat) gap -
S1613-p
PsPCTDss_______
0 2
LRP6 (human) PsPCTDss_______ S1613-p
LRP6 (mouse) PsPCTDSS_______ S1613
LRP6 (rat) gap -