Other Species / Isoforms
  MCR (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

 HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
T3-p
_____MEtKGyHsLP
0 1
MCR (human) _____MEtKGyHsLP T3-p
MCR (mouse) _____METKGYHSLP T3
MCR (rat) _____METKGYHSLP T3
Y6-p
__MEtKGyHsLPEGL
0 1
MCR (human) __MEtKGyHsLPEGL Y6-p
MCR (mouse) __METKGYHSLPEGL Y6
MCR (rat) __METKGYHSLPEGL Y6
S8-p
MEtKGyHsLPEGLDM
0 1
MCR (human) MEtKGyHsLPEGLDM S8-p
MCR (mouse) METKGYHSLPEGLDM S8
MCR (rat) METKGYHSLPEGLDM S8
S23-p
ERRWGQVsQAVERSS
0 1
MCR (human) ERRWGQVsQAVERSS S23-p
MCR (mouse) ERRWSQVSQTLERSS S23
MCR (rat) ERRWSQVSQTLERSS S23
K89-sm
GILTSDIkTELESKE
Upstream
Downstream
3 0
Effects on Biological Processes:
  • transcription, induced
  • transcription, inhibited
Treatment
  • aldosterone
MCR (human) GILTSDIkTELESKE K89-sm
MCR (mouse) GILPSDIKTELESKE K89
MCR (rat) GILPSDIKTELESKE K89
S111-p
SMGLYMDsVRDADYS
Upstream
1 0
Kinase, in vitro:
  • CK2A1 (human)
Putative in vivo kinases:
  • CK2A1 (human)
MCR (human) SMGLYMDsVRDADYS S111-p
MCR (mouse) SMGLYMDSVRDAEYT S111
MCR (rat) SMGLYMDSVRDAEYT S111
S129-p
QNQQGSMsPAKIYQN
0 2
MCR (human) QNQQGSMsPAKIYQN S129-p
MCR (mouse) QNQQGSLSPAKIYQN S129
MCR (rat) QNQQGSLSPTKIYQN S129
S168-p
LRSFMSDsGSSVNGG
0 1
MCR (human) LRSFMSDsGSSVNGG S168-p
MCR (mouse) LRSFMPDSGTSMNGG S168
MCR (rat) LRSFMPDSAASMNGG S168
S183-p
VMRAVVKsPIMCHEK
0 4
MCR (human) VMRAVVKsPIMCHEK S183-p
MCR (mouse) ALRAIVKsPIICHEK S183-p
MCR (rat) ALRAIVKSPIICHEK S183
S196-p
EKSPSVCsPLNMTSS
Upstream
Downstream
1 0
Effects on Modified Protein
  • protein degradation
  • ubiquitination
Effects on Biological Processes:
  • transcription, inhibited
Kinase, in vitro:
  • ERK1 (human)
Putative in vivo kinases:
  • ERK1 (human)
  • ERK2 (human)
Treatment
  • aldosterone
  • FR180204
  • PD98059
MCR (human) EKSPSVCsPLNMTSS S196-p
MCR (mouse) EKSPSVCSPLNMPSS S196
MCR (rat) EKSSSVSSPLNMASS S196
S227-p
FGSFPVHsPITQGTP
Upstream
Downstream
1 0
Effects on Modified Protein
  • protein degradation
  • ubiquitination
Effects on Biological Processes:
  • transcription, inhibited
Kinase, in vitro:
  • ERK1 (human)
Putative in vivo kinases:
  • ERK1 (human)
  • ERK2 (human)
Treatment
  • aldosterone
  • FR180204
  • PD98059
MCR (human) FGSFPVHsPITQGTP S227-p
MCR (mouse) FGSFPVHSPITQGTS S227
MCR (rat) FGSFPVHSPITQGTS S227
S238-p
QGTPLTCsPNVENRG
Upstream
Downstream
1 0
Effects on Modified Protein
  • protein degradation
  • ubiquitination
Effects on Biological Processes:
  • transcription, inhibited
Kinase, in vitro:
  • ERK1 (human)
Putative in vivo kinases:
  • ERK1 (human)
  • ERK2 (human)
Treatment
  • aldosterone
  • FR180204
  • PD98059
MCR (human) QGTPLTCsPNVENRG S238-p
MCR (mouse) QGTSLTCSPSVENRG S238
MCR (rat) QGTSLTCSPSVENRG S238
S248-p
VENRGSRsHsPAHAs
0 2
MCR (human) VENRGSRsHsPAHAs S248-p
MCR (mouse) VENRGSRsHsPVHAS S248-p
MCR (rat) VENRGSRSHSPTHAS S248
S250-p
NRGSRsHsPAHAsNV
0 7
MCR (human) NRGSRsHsPAHAsNV S250-p
MCR (mouse) NRGSRsHsPVHASNV S250-p
MCR (rat) NRGSRSHSPTHASNV S250
S255-p
sHsPAHAsNVGsPLs
Upstream
0 1
Regulatory protein:
  • NCCT (mouse)
  • WNK4 (mouse)
Treatment
  • angiotensin_2
  • high-potassium diet
  • high-salt diet
  • losartan
  • low-salt diet
MCR (human) sHsPAHAsNVGsPLs S255-p
MCR (mouse) sHsPVHASNVGsPLs S255
MCR (rat) SHSPTHASNVGSPLS S255
S259-p
AHAsNVGsPLssPLS
0 3
MCR (human) AHAsNVGsPLssPLS S259-p
MCR (mouse) VHASNVGsPLssPLS S259-p
MCR (rat) THASNVGSPLSSPLS S259
S262-p
sNVGsPLssPLSSMK
0 2
MCR (human) sNVGsPLssPLSSMK S262-p
MCR (mouse) SNVGsPLssPLSSMK S262-p
MCR (rat) SNVGSPLSSPLSSMK S262
S263-p
NVGsPLssPLSSMKS
Upstream
Downstream
1 1
Effects on Modified Protein
  • protein degradation
  • ubiquitination
Effects on Biological Processes:
  • transcription, inhibited
Kinase, in vitro:
  • ERK1 (human)
Putative in vivo kinases:
  • ERK1 (human)
  • ERK2 (human)
Treatment
  • aldosterone
  • FR180204
  • PD98059
MCR (human) NVGsPLssPLSSMKS S263-p
MCR (mouse) NVGsPLssPLSSMKS S263-p
MCR (rat) NVGSPLSSPLSSMKS S263
S274-p
SMKSSISsPPSHCSV
0 2
MCR (human) SMKSSISsPPSHCSV S274-p
MCR (mouse) SMKSPISSPPSHCSV S274
MCR (rat) SMKSPISSPPSHCSV S274
S283-p
PSHCSVKsPVSsPNN
0 6
MCR (human) PSHCSVKsPVSsPNN S283-p
MCR (mouse) PSHCSVKsPVSsPNN S283-p
MCR (rat) PSHCSVKsPVSsPNN S283-p
S287-p
SVKsPVSsPNNVTLR
Upstream
Downstream
1 5
Effects on Modified Protein
  • protein degradation
  • ubiquitination
Effects on Biological Processes:
  • transcription, inhibited
Kinase, in vitro:
  • ERK1 (human)
Putative in vivo kinases:
  • ERK1 (human)
  • ERK2 (human)
Treatment
  • aldosterone
  • FR180204
  • PD98059
MCR (human) SVKsPVSsPNNVTLR S287-p
MCR (mouse) SVKsPVSsPNNVPLR S287-p
MCR (rat) SVKsPVSsPNNVPLR S287-p
S299-p
TLRSSVSsPANINNS
0 5
MCR (human) TLRSSVSsPANINNS S299-p
MCR (mouse) PLRSSVSsPANLNNS S299-p
MCR (rat) PLRSSVSsPANLNNS S299-p
S311-p
NNSRCSVsSPSNTNN
0 1
MCR (human) NNSRCSVsSPSNTNN S311-p
MCR (mouse) NNSRCSVSsPSNTNN S311
MCR (rat) NNSRCSVSSPSNNTN S311
S312
NSRCSVsSPSNTNNR
0 1
MCR (human) NSRCSVsSPSNTNNR S312
MCR (mouse) NSRCSVSsPSNTNNR S312-p
MCR (rat) NSRCSVSSPSNNTNN S312
S361-p
TLRDVVPsPDTQEKG
Upstream
Downstream
1 2
Effects on Modified Protein
  • protein degradation
  • ubiquitination
Effects on Biological Processes:
  • transcription, inhibited
Kinase, in vitro:
  • ERK1 (human)
Putative in vivo kinases:
  • ERK1 (human)
  • ERK2 (human)
Treatment
  • aldosterone
  • FR180204
  • PD98059
MCR (human) TLRDVVPsPDTQEKG S361-p
MCR (mouse) AIQDMVPSPDTHEKG S361
MCR (rat) AIQDVVPSPDTHEKG S362
K399-sm
LNIVQYIkPEPDGAF
Upstream
Downstream
3 1
Effects on Biological Processes:
  • transcription, induced
  • transcription, inhibited
Treatment
  • aldosterone
MCR (human) LNIVQYIkPEPDGAF K399-sm
MCR (mouse) LNIVQYIKPEPDGAF K399
MCR (rat) LNIVQYIKSEPDGAF K400
S424-p
INSDSSFsVPIkQES
0 1
MCR (human) INSDSSFsVPIkQES S424-p
MCR (mouse) INPSSPFSVPIKQES S424
MCR (rat) ISPSSPFSVPIKQES S425
K428-sm
SSFsVPIkQESTKHS
Downstream
2 3
Effects on Biological Processes:
  • transcription, inhibited
MCR (human) SSFsVPIkQESTKHS K428-sm
MCR (mouse) SPFSVPIKQESSKHS K428
MCR (rat) SPFSVPIKQESSKHS K429
S459-p
FMDGSYFsFMDDkDY
Upstream
Downstream
1 0
Effects on Modified Protein
  • molecular association, regulation
Effects on Biological Processes:
  • transcription, induced
Kinase, in vitro:
  • CK2A1 (human)
Putative in vivo kinases:
  • CK2A1 (human)
MCR (human) FMDGSYFsFMDDkDY S459-p
MCR (mouse) FMDGSYFSFMDDKDY S459
MCR (rat) FMDGSYFSFMDDKDY S460
K464-ac
YFsFMDDkDYYSLSG
0 2
MCR (human) YFsFMDDkDYYSLSG K464-ac
MCR (mouse) YFSFMDDKDYYSLSG K464
MCR (rat) YFSFMDDKDYYSLSG K465
K494-sm
SGFPVGIkQEPDDGS
Upstream
Downstream
3 1
Effects on Biological Processes:
  • transcription, induced
  • transcription, inhibited
Treatment
  • aldosterone
MCR (human) SGFPVGIkQEPDDGS K494-sm
MCR (mouse) SAFPGGIkQEPDDGS K494-sm
MCR (rat) SAFPVGIKQEPDDGS K495
T532-p
YRIGAQGtISLSRSA
0 1
MCR (human) YRIGAQGtISLSRSA T532-p
MCR (mouse) YRIGAQGTIsLsRsP T532
MCR (rat) YRIGAQGTISLSRSP T533
S534
IGAQGtISLSRSARD
0 1
MCR (human) IGAQGtISLSRSARD S534
MCR (mouse) IGAQGTIsLsRsPRD S534-p
MCR (rat) IGAQGTISLSRSPRD S535
S536
AQGtISLSRSARDQs
0 1
MCR (human) AQGtISLSRSARDQs S536
MCR (mouse) AQGTIsLsRsPRDQS S536-p
MCR (rat) AQGTISLSRSPRDQS S537
S538
GtISLSRSARDQsFQ
0 1
MCR (human) GtISLSRSARDQsFQ S538
MCR (mouse) GTIsLsRsPRDQSFQ S538-p
MCR (rat) GTISLSRSPRDQSFQ S539
S543-p
SRSARDQsFQHLSSF
0 1
MCR (human) SRSARDQsFQHLSSF S543-p
MCR (mouse) sRsPRDQSFQHLSSF S543
MCR (rat) SRSPRDQSFQHLSSF S544
K680-ub
RKSKKLGkLKGIHEE
0 3
MCR (human) RKSKKLGkLKGIHEE K680-ub
MCR (mouse) RKSKKLGkLKGLHEE K678-ub
MCR (rat) RKSKKLGKLKGLHEE K681
S703-p
PPPPPPQsPEEGTTY
0 1
MCR (human) PPPPPPQsPEEGTTY S703-p
MCR (mouse) PPPPPPQSPEEGTTY S697
MCR (rat) PPPPPPQSPEEGTTY S700
T735-p
STISRALtPsPVMVL
0 2
MCR (human) STISRALtPsPVMVL T735-p
MCR (mouse) ASITRALTPSPSMIL T729
MCR (rat) TSITHALTPSPAMIL T732
S737-p
ISRALtPsPVMVLEN
0 1
MCR (human) ISRALtPsPVMVLEN S737-p
MCR (mouse) ITRALTPSPSMILEN S731
MCR (rat) ITHALTPSPAMILEN S734
T761-p
YDSSKPDtAENLLST
0 1
MCR (human) YDSSKPDtAENLLST T761-p
MCR (mouse) YDNSKPDTAESLLST T755
MCR (rat) YDNSKPDTAESLLST T758
T800-p
LPLEDQItLIQYSWM
Upstream
Downstream
1 0
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
Effects on Biological Processes:
  • transcription, induced
Kinase, in vitro:
  • CK1A (human)
Putative in vivo kinases:
  • CK1A (human)
  • CK1E (human)
Treatment
  • D4476
  • PF-4800567
  • PF-670462
MCR (human) LPLEDQItLIQYSWM T800-p
MCR (mouse) LPLEDQITLIQYSWM T794
MCR (rat) LPLEDQITLIQYSWM T797
S843-p
NEEKMHQsAMYELCQ
Upstream
Downstream
3 2
Effects on Modified Protein
  • intracellular localization
Effects on Biological Processes:
  • transcription, induced
  • transcription, inhibited
Kinase, in vitro:
  • ULK1 (human)
Putative in vivo kinases:
  • ULK1 (human)
Regulatory protein:
  • NCCT (mouse)
  • WNK4 (mouse)
Treatment
  • angiotensin_2
  • AZD8055
  • high-potassium diet
  • high-salt diet
  • losartan
  • low-salt diet
  • siRNA
MCR (human) NEEKMHQsAMYELCQ S843-p
MCR (mouse) NEEKMHQsAMYELCQ S837-p
MCR (rat) NEEKMHQSAMYELCQ S840
S936-p
DSMHDLVsDLLEFCF
Upstream
Downstream
1 0
Effects on Modified Protein
  • intracellular localization
Kinase, in vitro:
  • CK1A (human)
Treatment
  • D4476
  • PF-4800567
  • PF-670462
MCR (human) DSMHDLVsDLLEFCF S936-p
MCR (mouse) DSMHDLVNDLLEFCF N930
MCR (rat) DSMHDLVSDLLEFCF S933
K953-sm
FRESHALkVEFPAML
Upstream
Downstream
3 0
Effects on Biological Processes:
  • transcription, induced
  • transcription, inhibited
Treatment
  • aldosterone
MCR (human) FRESHALkVEFPAML K953-sm
MCR (mouse) FRESQALKVEFPAML K947
MCR (rat) FRESQALKVEFPAML K950
K970-ub
IISDQLPkVESGNAk
0 1
MCR (human) IISDQLPkVESGNAk K970-ub
MCR (mouse) IISDQLPKVESGNAK K964
MCR (rat) IITDQLPKVESGNAK K967
K977-ub
kVESGNAkPLYFHRK
0 1
MCR (human) kVESGNAkPLYFHRK K977-ub
MCR (mouse) KVESGNAKPLYFHRK K971
MCR (rat) KVESGNAKPLYFHRK K974