Other Species / Isoforms
  SGK1 (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

  HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
K41-ac
GLNDFIQkIANNSYA
0 1
SGK1 (human) GLNDFIQkIANNSYA K41-ac
SGK1 iso2 (human) GLNDFIQKIANNSYA K136
SGK1 iso3 (human) GLNDFIQKIANNSYA K55
SGK1 (mouse) GLNDFIQKIASNTYA K41
SGK1 (rat) GLNDFIQKLANNSYA K41
K50-ub
ANNSYACkHPEVQSI
0 1
SGK1 (human) ANNSYACkHPEVQSI K50-ub
SGK1 iso2 (human) ANNSYACKHPEVQSI K145
SGK1 iso3 (human) ANNSYACKHPEVQSI K64
SGK1 (mouse) ASNTYACKHAEVQSI K50
SGK1 (rat) ANNSYACKHPEVQSY K50
S74-p
ELMNANPsPPPsPsQ
Upstream
0 6
Treatment
  • MG132
  • MG132_withdrawal
  • selumetinib
  • vemurafenib
view more >
SGK1 (human) ELMNANPsPPPsPsQ S74-p
SGK1 iso2 (human) ELMNANPSPPPSPSQ S169
SGK1 iso3 (human) ELMNANPSPPPSPSQ S88
SGK1 (mouse) ELMNANPSPPPsPSQ S74
SGK1 (rat) ELMNANPSPPPSPSQ S74
S78-p
ANPsPPPsPsQQINL
Upstream
Downstream
6 2
SGK1 (human)
S78-p
SGK1 iso3 (human)
S92-p
SGK1 (mouse)
S78-p
SGK1 (rat)
S78-p
Effects on Biological Processes:
  • cell cycle regulation
Kinase, in vitro:
  • ERK5 (human)
Putative in vivo kinases:
  • ERK5 (human)
Treatment
  • 6-OHDA
  • carnosic acid
  • curcumin
  • EGF
  • IL-6
  • LY294002
  • rapamycin
  • SB202190
  • SB203580
  • sorafenib
  • wortmannin
  • XMD8-92
view more >
SGK1 (human) ANPsPPPsPsQQINL S78-p
SGK1 iso2 (human) ANPSPPPSPSQQINL S173
SGK1 iso3 (human) ANPSPPPSPSQQINL S92
SGK1 (mouse) ANPSPPPsPSQQINL S78-p
SGK1 (rat) ANPSPPPSPSQQINL S78
S80-p
PsPPPsPsQQINLGP
0 1
SGK1 (human) PsPPPsPsQQINLGP S80-p
SGK1 iso2 (human) PSPPPSPSQQINLGP S175
SGK1 iso3 (human) PSPPPSPSQQINLGP S94
SGK1 (mouse) PSPPPsPSQQINLGP S80
SGK1 (rat) PSPPPSPSQQINLGP S80
K94-ub
PSSNPHAkPSDFHFL
0 1
SGK1 (human) PSSNPHAkPSDFHFL K94-ub
SGK1 iso2 (human) PSSNPHAKPSDFHFL K189
SGK1 iso3 (human) PSSNPHAKPSDFHFL K108
SGK1 (mouse) PSSNPHAKPSDFHFL K94
SGK1 (rat) PSSNPHAKPSDFHFL K94
K102-ub
PSDFHFLkVIGKGSF
0 1
SGK1 (human) PSDFHFLkVIGKGSF K102-ub
SGK1 iso2 (human) PSDFHFLKVIGKGSF K197
SGK1 iso3 (human) PSDFHFLKVIGKGSF K116
SGK1 (mouse) PSDFHFLKVIGKGSF K102
SGK1 (rat) PSDFHFLKVIGKGSF K102
K111-ub
IGKGSFGkVLLARHk
0 2
SGK1 (human) IGKGSFGkVLLARHk K111-ub
SGK1 iso2 (human) IGKGSFGKVLLARHK K206
SGK1 iso3 (human) IGKGSFGKVLLARHK K125
SGK1 (mouse) IGKGSFGKVLLARHK K111
SGK1 (rat) IGKGSFGKVLLARHK K111
K118-ub
kVLLARHkAEEVFyA
0 1
SGK1 (human) kVLLARHkAEEVFyA K118-ub
SGK1 iso2 (human) KVLLARHKAEEVFYA K213
SGK1 iso3 (human) KVLLARHKAEEVFYA K132
SGK1 (mouse) KVLLARHKAEEVFYA K118
SGK1 (rat) KVLLARHKAEEAFYA K118
Y124-p
HkAEEVFyAVKVLQK
0 1
SGK1 (human) HkAEEVFyAVKVLQK Y124-p
SGK1 iso2 (human) HKAEEVFYAVKVLQK Y219
SGK1 iso3 (human) HKAEEVFYAVKVLQK Y138
SGK1 (mouse) HKAEEVFYAVKVLQK Y124
SGK1 (rat) HKAEEAFYAVKVLQK Y124
S255
IEHNSTTStFCGTPE
1 0
SGK1 (human) IEHNSTTStFCGTPE S255
SGK1 iso2 (human) IEHNSTTSTFCGTPE S350
SGK1 iso3 (human) IEHNSTTSTFCGTPE S269
SGK1 (mouse) IEHNGTTSTFCGTPE S255
SGK1 (rat) IEHNGTTstFCGTPE S255-p
T256-p
EHNSTTStFCGTPEY
Upstream
Downstream
15 0
Effects on Modified Protein
  • enzymatic activity, induced
  • molecular association, regulation
  • phosphorylation
Effects on Biological Processes:
  • apoptosis, inhibited
  • signaling pathway regulation
  • transcription, induced
Kinase, in vitro:
  • PDK1 (human)
Putative in vivo kinases:
  • PDK1 (human)
  • PIK3C2A (human)
Regulatory protein:
  • HSP90A (human)
  • PDK1 (human)
  • Raptor (human)
  • TSC2 (human)
view more >
Treatment
  • aldosterone
  • amino_acids
  • calyculin_A
  • ceramide
  • dexamethasone
  • EMD638683
  • eplerenone
  • estradiol
  • geldanamycin
  • high-fat diet
  • high_glucose
  • IL-6
  • insulin
  • LY294002
  • okadaic_acid
  • palmitate
  • PD98059
  • rapamycin
  • SB202190
  • SB203580
  • siRNA
  • streptozotocin
  • vanadate
  • wortmannin
view more >
SGK1 (human) EHNSTTStFCGTPEY T256-p
SGK1 iso2 (human) EHNSTTSTFCGTPEY T351
SGK1 iso3 (human) EHNSTTSTFCGTPEY T270
SGK1 (mouse) EHNGTTSTFCGTPEY T256
SGK1 (rat) EHNGTTstFCGTPEY T256-p
K271-ub
LAPEVLHkQPYDRTV
0 1
SGK1 (human) LAPEVLHkQPYDRTV K271-ub
SGK1 iso2 (human) LAPEVLHKQPYDRTV K366
SGK1 iso3 (human) LAPEVLHKQPYDRTV K285
SGK1 (mouse) LAPEVLHKQPYDRTV K271
SGK1 (rat) LAPEVLHKQPYDRTV K271
K317-ub
LNKPLQLkPNITNSA
0 1
SGK1 (human) LNKPLQLkPNITNSA K317-ub
SGK1 iso2 (human) LNKPLQLKPNITNSA K412
SGK1 iso3 (human) LNKPLQLKPNITNSA K331
SGK1 (mouse) LNKPLQLKPNITNSA K317
SGK1 (rat) gap -
K343-ub
RTKRLGAkDDFMEIK
0 1
SGK1 (human) RTKRLGAkDDFMEIK K343-ub
SGK1 iso2 (human) RTKRLGAKDDFMEIK K438
SGK1 iso3 (human) RTKRLGAKDDFMEIK K357
SGK1 (mouse) RTKRLGAKDDFMEIK K343
SGK1 (rat) RTKRLGAKDDFMEIK K342
K367-ub
WDDLINKkItPPFNP
0 1
SGK1 (human) WDDLINKkItPPFNP K367-ub
SGK1 iso2 (human) WDDLINKKITPPFNP K462
SGK1 iso3 (human) WDDLINKKITPPFNP K381
SGK1 (mouse) WDDLINKKITPPFNP K367
SGK1 (rat) WDDLINKKITPPFNP K366
T369-p
DLINKkItPPFNPNV
Upstream
Downstream
2 0
Effects on Modified Protein
  • enzymatic activity, induced
Putative in vivo kinases:
  • PKACA (human)
Treatment
  • cAMP_analog
  • H-89
  • insulin
  • wortmannin
view more >
SGK1 (human) DLINKkItPPFNPNV T369-p
SGK1 iso2 (human) DLINKKITPPFNPNV T464
SGK1 iso3 (human) DLINKKITPPFNPNV T383
SGK1 (mouse) DLINKKITPPFNPNV T369
SGK1 (rat) DLINKKITPPFNPNV T368
S377-p
PPFNPNVsGPNDLRH
Upstream
1 0
Kinase, in vitro:
  • NEK6 (human)
SGK1 (human) PPFNPNVsGPNDLRH S377-p
SGK1 iso2 (human) PPFNPNVSGPNDLRH S472
SGK1 iso3 (human) PPFNPNVSGPNDLRH S391
SGK1 (mouse) PPFNPNVSGPSDLRH S377
SGK1 (rat) PPFNPNVSGPSDLRH S376
S397-p
TEEPVPNsIGksPDS
Downstream
1 5
Effects on Modified Protein
  • enzymatic activity, induced
  • phosphorylation
SGK1 (human) TEEPVPNsIGksPDS S397-p
SGK1 iso2 (human) TEEPVPNSIGKSPDS S492
SGK1 iso3 (human) TEEPVPNSIGKSPDS S411
SGK1 (mouse) TEEPVPSSIGRSPDS S397
SGK1 (rat) TEEPVPSSIGRSPDS S396
K400-ub
PVPNsIGksPDSVLV
0 1
SGK1 (human) PVPNsIGksPDSVLV K400-ub
SGK1 iso2 (human) PVPNSIGKSPDSVLV K495
SGK1 iso3 (human) PVPNSIGKSPDSVLV K414
SGK1 (mouse) PVPSSIGRSPDSILV R400
SGK1 (rat) PVPSSIGRSPDSILV R399
S401-p
VPNsIGksPDSVLVT
Upstream
Downstream
1 5
Effects on Modified Protein
  • enzymatic activity, induced
  • phosphorylation
Treatment
  • MG132
  • MG132_withdrawal
SGK1 (human) VPNsIGksPDSVLVT S401-p
SGK1 iso2 (human) VPNSIGKSPDSVLVT S496
SGK1 iso3 (human) VPNSIGKSPDSVLVT S415
SGK1 (mouse) VPSSIGRSPDSILVT S401
SGK1 (rat) VPSSIGRSPDSILVT S400
S422-p
AEAFLGFsYAPPTDS
Upstream
Downstream
30 0
Effects on Modified Protein
  • enzymatic activity, induced
  • intracellular localization
  • molecular association, regulation
  • phosphorylation
  • protein stabilization
Effects on Biological Processes:
  • apoptosis, inhibited
  • cell cycle regulation
  • cell growth, inhibited
  • signaling pathway regulation
  • transcription, inhibited
Kinase, in vitro:
  • mTOR (human)
  • NEK6 (human)
  • SGK1 (human)
view more >
Putative in vivo kinases:
  • mTOR (human)
  • SGK1 (human)
Putative upstream phosphatases:
  • PPP2CA (human)
  • PPP5C (human)
Regulatory protein:
  • DNAPK (human)
  • HSP90A (human)
  • PABIR1 (human)
  • PABIR2 (human)
  • PIK3C2A (human)
  • PKCA (human)
  • Raptor (human)
  • RICTOR (human)
  • SGK1 (human)
  • Sin1 (human)
  • TORC2 (human)
  • TSC2 (human)
view more >
Treatment
  • Akt-I-1
  • amino_acids
  • angiotensin_2
  • AZD7648
  • AZD8055
  • bacterial infection
  • bleomycin
  • calyculin_A
  • cAMP_analog
  • carnosic acid
  • ceramide
  • curcumin
  • dexamethasone
  • EMD638683
  • estradiol
  • etoposide
  • geldanamycin
  • H-89
  • H2O2
  • high-fat diet
  • high_glucose
  • IGF-1
  • INK-128
  • insulin
  • LY294002
  • NIPP1
  • okadaic_acid
  • palmitate
  • PI-103
  • pictilisib
  • PIK90
  • PP242
  • rapamycin
  • SB216763
  • serum
  • siRNA
  • streptozotocin
  • Torin1
  • wortmannin
view more >
SGK1 (human) AEAFLGFsYAPPTDS S422-p
SGK1 iso2 (human) AEAFLGFSYAPPTDS S517
SGK1 iso3 (human) AEAFLGFSYAPPTDS S436
SGK1 (mouse) AEAFLGFsYAPPVDS S422-p
SGK1 (rat) AEAFLGFsYAPPMDS S421-p