Other Species / Isoforms
  TOP1 (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

 HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
S2-p
______MsGDHLHND
Upstream
0 14
Regulatory protein:
  • PRP4 (human)
Treatment
  • ionizing_radiation
  • nocodazole
TOP1 (human) ______MsGDHLHND S2-p
TOP1 (mouse) ______MsGDHLHND S2-p
TOP1 (rat) ______MSGDHLHND S2
TOP1 (cow) ______MSGDHLHND S2
S10-p
GDHLHNDsQIEADFR
Upstream
Downstream
3 30
Effects on Modified Protein
  • protein degradation
Kinase, in vitro:
  • CK2A1 (human)
  • DNAPK (human)
Regulatory protein:
  • PRP4 (human)
  • PTEN (human)
Treatment
  • aphidicolin
  • EGF
  • hydroxyurea
  • ionizing_radiation
  • nocodazole
  • taxol
TOP1 (human) GDHLHNDsQIEADFR S10-p
TOP1 (mouse) GDHLHNDsQIEADFR S10-p
TOP1 (rat) GDHLHNDsQIEADFR S10-p
TOP1 (cow) GDHLHNDSQIEADFR S10
S21-p
ADFRLNDsHKHKDKH
Upstream
Downstream
1 4
Effects on Modified Protein
  • enzymatic activity, induced
Kinase, in vitro:
  • PKCA (human)
Treatment
  • aphidicolin
  • hydroxyurea
  • nocodazole
  • taxol
TOP1 (human) ADFRLNDsHKHKDKH S21-p
TOP1 (mouse) ADFRLNDSHKHKDKH S21
TOP1 (rat) ADFRLNDSHKHKDKH S21
TOP1 (cow) ADFRLNDSHKHKDKH S21
S57-p
SNSEHKDsEKKHKEK
Upstream
0 1
Treatment
  • nocodazole
TOP1 (human) SNSEHKDsEKKHKEK S57-p
TOP1 (mouse) SNSEHKDSEKKHKEK S59
TOP1 (rat) SNSEHKDSEKKHKEK S59
TOP1 (cow) SNSEHKDSEKKHKEK S59
S73-p
KTKHKDGssEKHKDK
0 2
TOP1 (human) KTKHKDGssEKHKDK S73-p
TOP1 (mouse) KTKHKDGSSEKHKDK S75
TOP1 (rat) KTKHKDGSSDKHKDK S75
TOP1 (cow) KTKHKDGSSEKHKDK S75
S74-p
TKHKDGssEKHKDKH
0 1
TOP1 (human) TKHKDGssEKHKDKH S74-p
TOP1 (mouse) TKHKDGSSEKHKDKH S76
TOP1 (rat) TKHKDGSSDKHKDKH S76
TOP1 (cow) TKHKDGSSEKHKDKH S76
K103-sm
ASGDAKIkKEKENGF
Upstream
Downstream
2 1
Effects on Modified Protein
  • intracellular localization
Treatment
  • CPT
TOP1 (human) ASGDAKIkKEKENGF K103-sm
TOP1 (mouse) AAGDAKIKKEKENGF K105
TOP1 (rat) AAGDAKIKKEKENGF K105
TOP1 (cow) ASGDAKIKKEKENGF K105
S111-p
KEKENGFssPPQIkD
0 15
TOP1 (human) KEKENGFssPPQIkD S111-p
TOP1 (mouse) KEKENGFssPPRIKD S113-p
TOP1 (rat) KEKENGFSsPPRIKD S113
TOP1 (cow) KEKENGFSSPPRIKD S113
S112-p
EKENGFssPPQIkDE
Upstream
1 25
Kinase, in vitro:
  • CDK1 (human)
Treatment
  • aphidicolin
  • hydroxyurea
  • nocodazole
  • taxol
TOP1 (human) EKENGFssPPQIkDE S112-p
TOP1 (mouse) EKENGFssPPRIKDE S114-p
TOP1 (rat) EKENGFSsPPRIKDE S114-p
TOP1 (cow) EKENGFSSPPRIKDE S114
K117-sm
FssPPQIkDEPEDDG
Upstream
Downstream
4 5
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
Effects on Biological Processes:
  • apoptosis, induced
Regulatory protein:
  • UBE2H (human)
Treatment
  • camptothecin
  • CPT
TOP1 (human) FssPPQIkDEPEDDG K117-sm
TOP1 (mouse) FssPPRIKDEPEDDG K119
TOP1 (rat) FSsPPRIKDEPEDDG K119
TOP1 (cow) FSSPPRIKDEPEDDG K119
Y125-p
DEPEDDGyFVPPKED
0 10
TOP1 (human) DEPEDDGyFVPPKED Y125-p
TOP1 (mouse) DEPEDDGYFAPPKED Y127
TOP1 (rat) DEPEDDGYFAPPKED Y127
TOP1 (cow) DEPEDDGYFAPPKED Y127
K134-ac
VPPKEDIkPLkRPRD
0 1
TOP1 (human) VPPKEDIkPLkRPRD K134-ac
TOP1 (mouse) APPKEDIKPLKRLRD K136
TOP1 (rat) APPKEDIKPLKRPRD K136
TOP1 (cow) APPKEDIKPLKRPRD K136
K134-sm
VPPKEDIkPLkRPRD
0 1
TOP1 (human) VPPKEDIkPLkRPRD K134-sm
TOP1 (mouse) APPKEDIKPLKRLRD K136
TOP1 (rat) APPKEDIKPLKRPRD K136
TOP1 (cow) APPKEDIKPLKRPRD K136
K137-ub
KEDIkPLkRPRDEDD
0 1
TOP1 (human) KEDIkPLkRPRDEDD K137-ub
TOP1 (mouse) KEDIKPLKRLRDEDD K139
TOP1 (rat) KEDIKPLKRPRDEDD K139
TOP1 (cow) KEDIKPLKRPRDEDD K139
Y147-p
RDEDDADykPKKIkT
0 2
TOP1 (human) RDEDDADykPKKIkT Y147-p
TOP1 (mouse) RDEDDADYKPKKIKT Y149
TOP1 (rat) RDEDDADYkPKKIKT Y149
TOP1 (cow) RDEDDADYKPKKIKT Y149
K148-ac
DEDDADykPKKIkTE
0 4
TOP1 (human) DEDDADykPKKIkTE K148-ac
TOP1 (mouse) DEDDADYKPKKIKTE K150
TOP1 (rat) DEDDADYkPKKIKTE K150-ac
TOP1 (cow) DEDDADYKPKKIKTE K150
K148-ub
DEDDADykPKKIkTE
0 1
TOP1 (human) DEDDADykPKKIkTE K148-ub
TOP1 (mouse) DEDDADYKPKKIKTE K150
TOP1 (rat) DEDDADYKPKKIKTE K150
TOP1 (cow) DEDDADYKPKKIKTE K150
K148-sm
DEDDADykPKKIkTE
0 1
TOP1 (human) DEDDADykPKKIkTE K148-sm
TOP1 (mouse) DEDDADYKPKKIKTE K150
TOP1 (rat) DEDDADYKPKKIKTE K150
TOP1 (cow) DEDDADYKPKKIKTE K150
K153-sm
DykPKKIkTEDTkKE
Upstream
Downstream
3 2
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
Effects on Biological Processes:
  • apoptosis, induced
Regulatory protein:
  • UBE2H (human)
Treatment
  • camptothecin
  • CPT
TOP1 (human) DykPKKIkTEDTkKE K153-sm
TOP1 (mouse) DYKPKKIKTEDIKKE K155
TOP1 (rat) DYkPKKIKTEDIKKE K155
TOP1 (cow) DYKPKKIKTEDIKKE K155
K158-sm
KIkTEDTkKEKKRkL
0 1
TOP1 (human) KIkTEDTkKEKKRkL K158-sm
TOP1 (mouse) KIKTEDIKKEKKRKs K160
TOP1 (rat) KIKTEDIKKEKKRKL K160
TOP1 (cow) KIKTEDIKKEKKRKL K160
K164-ac
TkKEKKRkLEEEEDG
0 1
TOP1 (human) TkKEKKRkLEEEEDG K164-ac
TOP1 (mouse) IKKEKKRKsEEEEDG K166
TOP1 (rat) IKKEKKRKLEEEEDG K166
TOP1 (cow) IKKEKKRKLEEEEDG K166
K164-sm
TkKEKKRkLEEEEDG
0 1
TOP1 (human) TkKEKKRkLEEEEDG K164-sm
TOP1 (mouse) IKKEKKRKsEEEEDG K166
TOP1 (rat) IKKEKKRKLEEEEDG K166
TOP1 (cow) IKKEKKRKLEEEEDG K166
L165
kKEKKRkLEEEEDGk
0 3
TOP1 (human) kKEKKRkLEEEEDGk L165
TOP1 (mouse) KKEKKRKsEEEEDGk S167-p
TOP1 (rat) KKEKKRKLEEEEDGk L167
TOP1 (cow) KKEKKRKLEEEEDGK L167
K172-ac
LEEEEDGkLKKPKNK
0 7
TOP1 (human) LEEEEDGkLKKPKNK K172-ac
TOP1 (mouse) sEEEEDGkLKKPKNK K174-ac
TOP1 (rat) LEEEEDGkLKKPKNK K174-ac
TOP1 (cow) LEEEEDGKLKKPKNK K174
K204-ub
KEEEQKWkWWEEERY
0 1
TOP1 (human) KEEEQKWkWWEEERY K204-ub
TOP1 (mouse) KEEEQKWKWWEEERY K206
TOP1 (rat) KEEEQKWKWWEEERY K206
TOP1 (cow) KEEEQKWKWWEEERY K208
K218-ub
YPEGIKWkFLEHkGP
0 2
TOP1 (human) YPEGIKWkFLEHkGP K218-ub
TOP1 (mouse) YPEGIKWKFLEHKGP K220
TOP1 (rat) YPEGIKWKFLEHKGP K220
TOP1 (cow) YPEGIKWKFLEHKGP K222
K223-ub
KWkFLEHkGPVFAPP
0 3
TOP1 (human) KWkFLEHkGPVFAPP K223-ub
TOP1 (mouse) KWKFLEHKGPVFAPP K225
TOP1 (rat) KWKFLEHKGPVFAPP K225
TOP1 (cow) KWKFLEHKGPVFAPP K227
K239-ub
EPLPENVkFYYDGkV
0 2
TOP1 (human) EPLPENVkFYYDGkV K239-ub
TOP1 (mouse) EPLPESVKFYYDGKV K241
TOP1 (rat) EPLPEGVKFYYDGKV K241
TOP1 (cow) EPLPENVKFYYDGKV K243
K245-ac
VkFYYDGkVMKLSPk
0 1
TOP1 (human) VkFYYDGkVMKLSPk K245-ac
TOP1 (mouse) VKFYYDGKVMKLSPk K247
TOP1 (rat) VKFYYDGKVMKLSPK K247
TOP1 (cow) VKFYYDGKVMKLSPK K249
K245-ub
VkFYYDGkVMKLSPk
0 5
TOP1 (human) VkFYYDGkVMKLSPk K245-ub
TOP1 (mouse) VKFYYDGKVMKLSPk K247
TOP1 (rat) VKFYYDGKVMKLSPK K247
TOP1 (cow) VKFYYDGKVMKLSPK K249
K252-ub
kVMKLSPkAEEVATF
0 6
TOP1 (human) kVMKLSPkAEEVATF K252-ub
TOP1 (mouse) KVMKLSPkAEEVATF K254-ub
TOP1 (rat) KVMKLSPKAEEVATF K254
TOP1 (cow) KVMKLSPKAEEVATF K256
K262-ac
EVATFFAkMLDHEyT
Upstream
0 1
Treatment
  • vorinostat
TOP1 (human) EVATFFAkMLDHEyT K262-ac
TOP1 (mouse) EVATFFAKMLDHEyt K264
TOP1 (rat) EVATFFAKMLDHEYT K264
TOP1 (cow) EVATFFAKMLDHEYT K266
K262-ub
EVATFFAkMLDHEyT
0 3
TOP1 (human) EVATFFAkMLDHEyT K262-ub
TOP1 (mouse) EVATFFAKMLDHEyt K264
TOP1 (rat) EVATFFAKMLDHEYT K264
TOP1 (cow) EVATFFAKMLDHEYT K266
Y268-p
AkMLDHEyTTkEIFR
Upstream
1 3
Kinase, in vitro:
  • Abl (human)
TOP1 (human) AkMLDHEyTTkEIFR Y268-p
TOP1 (mouse) AKMLDHEytTKEIFR Y270-p
TOP1 (rat) AKMLDHEYTTKEIFR Y270
TOP1 (cow) AKMLDHEYTTKEIFR Y272
T269
kMLDHEyTTkEIFRK
0 1
TOP1 (human) kMLDHEyTTkEIFRK T269
TOP1 (mouse) KMLDHEytTKEIFRK T271-p
TOP1 (rat) KMLDHEYTTKEIFRK T271
TOP1 (cow) KMLDHEYTTKEIFRK T273
K271-ac
LDHEyTTkEIFRKNF
0 1
TOP1 (human) LDHEyTTkEIFRKNF K271-ac
TOP1 (mouse) LDHEytTKEIFRKNF K273
TOP1 (rat) LDHEYTTKEIFRKNF K273
TOP1 (cow) LDHEYTTKEIFRKNF K275
K280-ac
IFRKNFFkDWRKEMT
0 2
TOP1 (human) IFRKNFFkDWRKEMT K280-ac
TOP1 (mouse) IFRKNFFKDWRKEMT K282
TOP1 (rat) IFRKNFFKDWRKEMT K282
TOP1 (cow) IFRKNFFKDWRKEMT K284
K280-ub
IFRKNFFkDWRKEMT
0 3
TOP1 (human) IFRKNFFkDWRKEMT K280-ub
TOP1 (mouse) IFRKNFFKDWRKEMT K282
TOP1 (rat) IFRKNFFKDWRKEMT K282
TOP1 (cow) IFRKNFFKDWRKEMT K284
T295-p
NEEKNIItNLsKCDF
0 1
TOP1 (human) NEEKNIItNLsKCDF T295-p
TOP1 (mouse) NDEKNTITNLSKCDF T297
TOP1 (rat) NDEKNTITNLSKCDF T297
TOP1 (cow) NEEKNIITNLSKCDF T299
S298-p
KNIItNLsKCDFtQM
0 2
TOP1 (human) KNIItNLsKCDFtQM S298-p
TOP1 (mouse) KNTITNLSKCDFTQM S300
TOP1 (rat) KNTITNLSKCDFTQM S300
TOP1 (cow) KNIITNLSKCDFTQM S302
T303-p
NLsKCDFtQMSQYFK
0 1
TOP1 (human) NLsKCDFtQMSQYFK T303-p
TOP1 (mouse) NLSKCDFTQMSQYFK T305
TOP1 (rat) NLSKCDFTQMSQYFK T305
TOP1 (cow) NLSKCDFTQMSQYFK T307
K326-ub
MSKEEKLkIKEENEK
0 1
TOP1 (human) MSKEEKLkIKEENEK K326-ub
TOP1 (mouse) MSKEEKLKIKEENEK K328
TOP1 (rat) MSKEEKLKIKEENEK K328
TOP1 (cow) MSKEEKLKIKEENEK K330
K336-sm
EENEKLLkEYGFCIM
0 1
TOP1 (human) EENEKLLkEYGFCIM K336-sm
TOP1 (mouse) EENEKLLKEYGFCVM K338
TOP1 (rat) EENEKLLKEYGFCVM K338
TOP1 (cow) EENEKLLKEYGFCVM K340
K347-ac
FCIMDNHkERIANFk
0 1
TOP1 (human) FCIMDNHkERIANFk K347-ac
TOP1 (mouse) FCVMDNHRERIANFK R349
TOP1 (rat) FCVMDNHRERIANFK R349
TOP1 (cow) FCVMDNHRERIANFK R351
K347-ub
FCIMDNHkERIANFk
0 2
TOP1 (human) FCIMDNHkERIANFk K347-ub
TOP1 (mouse) FCVMDNHRERIANFK R349
TOP1 (rat) FCVMDNHRERIANFK R349
TOP1 (cow) FCVMDNHRERIANFK R351
K354-ub
kERIANFkIEPPGLF
0 2
TOP1 (human) kERIANFkIEPPGLF K354-ub
TOP1 (mouse) RERIANFKIEPPGLF K356
TOP1 (rat) RERIANFKIEPPGLF K356
TOP1 (cow) RERIANFKIEPPGLF K358
K354-sm
kERIANFkIEPPGLF
0 1
TOP1 (human) kERIANFkIEPPGLF K354-sm
TOP1 (mouse) RERIANFKIEPPGLF K356
TOP1 (rat) RERIANFKIEPPGLF K356
TOP1 (cow) RERIANFKIEPPGLF K358
K369-ub
RGRGNHPkMGMLKRR
0 1
TOP1 (human) RGRGNHPkMGMLKRR K369-ub
TOP1 (mouse) RGRGNHPKMGMLKRR K371
TOP1 (rat) RGRGNHPKMGMLKRR K371
TOP1 (cow) RGRGNHPKMGMLKRR K373
K391-ub
INCSKDAkVPsPPPG
0 1
TOP1 (human) INCSKDAkVPsPPPG K391-ub
TOP1 (mouse) INCSKDAKVPsPPPG K393
TOP1 (rat) INCSKDAKVPSPPPG K393
TOP1 (cow) INCSKDAKVPSPPPG K395
K391-sm
INCSKDAkVPsPPPG
Downstream
1 0
Effects on Modified Protein
  • enzymatic activity, inhibited
  • molecular association, regulation
TOP1 (human) INCSKDAkVPsPPPG K391-sm
TOP1 (mouse) INCSKDAKVPsPPPG K393
TOP1 (rat) INCSKDAKVPSPPPG K393
TOP1 (cow) INCSKDAKVPSPPPG K395
S394-p
SKDAkVPsPPPGHkW
Upstream
1 9
Kinase, in vitro:
  • CDK1 (human)
Treatment
  • aphidicolin
  • hydroxyurea
  • nocodazole
  • taxol
TOP1 (human) SKDAkVPsPPPGHkW S394-p
TOP1 (mouse) SKDAKVPsPPPGHKW S396-p
TOP1 (rat) SKDAKVPSPPPGHKW S396
TOP1 (cow) SKDAKVPSPPPGHKW S398
K400-ub
PsPPPGHkWKEVRHD
0 2
TOP1 (human) PsPPPGHkWKEVRHD K400-ub
TOP1 (mouse) PsPPPGHKWKEVRHD K402
TOP1 (rat) PSPPPGHKWKEVRHD K402
TOP1 (cow) PSPPPGHKWKEVRHD K404
S423-p
WTENIQGsIKyIMLN
0 1
TOP1 (human) WTENIQGsIKyIMLN S423-p
TOP1 (mouse) WTENIQGSIKYIMLN S425
TOP1 (rat) WTENIQGSIKYIMLN S425
TOP1 (cow) WTENIQGSIKYIMLN S427
Y426-p
NIQGsIKyIMLNPSS
0 2
TOP1 (human) NIQGsIKyIMLNPSS Y426-p
TOP1 (mouse) NIQGSIKYIMLNPSS Y428
TOP1 (rat) NIQGSIKYIMLNPSS Y428
TOP1 (cow) NIQGSIKYIMLNPSS Y430
K436-sm
LNPSSRIkGEKDWQk
Downstream
1 0
Effects on Modified Protein
  • enzymatic activity, inhibited
  • molecular association, regulation
TOP1 (human) LNPSSRIkGEKDWQk K436-sm
TOP1 (mouse) LNPSSRIKGEKDWQK K438
TOP1 (rat) LNPSSRIKGEKDWQK K438
TOP1 (cow) LNPSSRIKGEKDWQK K440
K443-ac
kGEKDWQkyETARRL
0 1
TOP1 (human) kGEKDWQkyETARRL K443-ac
TOP1 (mouse) KGEKDWQKYETARRL K445
TOP1 (rat) KGEKDWQKYETARRL K445
TOP1 (cow) KGEKDWQKYETARRL K447
Y444-p
GEKDWQkyETARRLK
0 5
TOP1 (human) GEKDWQkyETARRLK Y444-p
TOP1 (mouse) GEKDWQKYETARRLK Y446
TOP1 (rat) GEKDWQKYETARRLK Y446
TOP1 (cow) GEKDWQKYETARRLK Y448
K456-ub
RLKKCVDkIRNQYRE
0 1
TOP1 (human) RLKKCVDkIRNQYRE K456-ub
TOP1 (mouse) RLKKCVDKIRNQYRE K458
TOP1 (rat) RLKKCVDKIRNQYRE K458
TOP1 (cow) RLKKCVDKIRNQYRE K460
K466-m1
NQYREDWkSKEMkVR
0 1
TOP1 (human) NQYREDWkSKEMkVR K466-m1
TOP1 (mouse) NQYREDWKSKEMKVR K468
TOP1 (rat) NQYREDWKSKEMKVR K468
TOP1 (cow) NQYREDWKSKEMKVR K470
K471-m1
DWkSKEMkVRQRAVA
0 1
TOP1 (human) DWkSKEMkVRQRAVA K471-m1
TOP1 (mouse) DWKSKEMKVRQRAVA K473
TOP1 (rat) DWKSKEMKVRQRAVA K473
TOP1 (cow) DWKSKEMKVRQRAVA K475
Y480-p
RQRAVALyFIDkLAL
0 2
TOP1 (human) RQRAVALyFIDkLAL Y480-p
TOP1 (mouse) RQRAVALYFIDKLAL Y482
TOP1 (rat) RQRAVALYFIDKLAL Y482
TOP1 (cow) RQRAVALYFIDKLAL Y484
K484-ub
VALyFIDkLALRAGN
0 3
TOP1 (human) VALyFIDkLALRAGN K484-ub
TOP1 (mouse) VALYFIDKLALRAGN K486
TOP1 (rat) VALYFIDKLALRAGN K486
TOP1 (cow) VALYFIDKLALRAGN K488
K493-ub
ALRAGNEkEEGETAD
0 1
TOP1 (human) ALRAGNEkEEGETAD K493-ub
TOP1 (mouse) ALRAGNEKEEGETAD K495
TOP1 (rat) ALRAGNEKEEGETAD K495
TOP1 (cow) ALRAGNEKEEGETAD K497
S506-p
ADTVGCCsLRVEHIN
Upstream
Downstream
3 0
Effects on Modified Protein
  • molecular association, regulation
Kinase, in vitro:
  • CK2A1 (human)
Treatment
  • camptothecin
  • CK2_activator
  • CK2_inhibitor
  • TBB
TOP1 (human) ADTVGCCsLRVEHIN S506-p
TOP1 (mouse) ADTVGCCSLRVEHIN S508
TOP1 (rat) ADTVGCCSLRVEHIN S508
TOP1 (cow) ADTVGCCSLRVEHIN S510
K545-ac
YNKVPVEkRVFkNLQ
0 1
TOP1 (human) YNKVPVEkRVFkNLQ K545-ac
TOP1 (mouse) YNKVPVEKRVFKNLQ K547
TOP1 (rat) YNKVPVEKRVFKNLQ K547
TOP1 (cow) YNKVPVEKRVFKNLQ K549
K545-ub
YNKVPVEkRVFkNLQ
0 1
TOP1 (human) YNKVPVEkRVFkNLQ K545-ub
TOP1 (mouse) YNKVPVEKRVFKNLQ K547
TOP1 (rat) YNKVPVEKRVFKNLQ K547
TOP1 (cow) YNKVPVEKRVFKNLQ K549
K549-ub
PVEkRVFkNLQLFME
0 2
TOP1 (human) PVEkRVFkNLQLFME K549-ub
TOP1 (mouse) PVEKRVFKNLQLFME K551
TOP1 (rat) PVEKRVFKNLQLFME K551
TOP1 (cow) PVEKRVFKNLQLFME K553
K558-ub
LQLFMENkQPEDDLF
0 1
TOP1 (human) LQLFMENkQPEDDLF K558-ub
TOP1 (mouse) LQLFMENKQPEDDLF K560
TOP1 (rat) LQLFMENKQPEDDLF K560
TOP1 (cow) LQLFMENKQPEDDLF K562
R567-m1
PEDDLFDrLNtGILN
0 1
TOP1 (human) PEDDLFDrLNtGILN R567-m1
TOP1 (mouse) PEDDLFDRLNTGILN R569
TOP1 (rat) PEDDLFDRLNTGILN R569
TOP1 (cow) PEDDLFDRLNTGILN R571
T570-p
DLFDrLNtGILNkHL
0 1
TOP1 (human) DLFDrLNtGILNkHL T570-p
TOP1 (mouse) DLFDRLNTGILNKHL T572
TOP1 (rat) DLFDRLNTGILNKHL T572
TOP1 (cow) DLFDRLNTGILNKHL T574
K575-ac
LNtGILNkHLQDLME
Upstream
0 1
Treatment
  • vorinostat
TOP1 (human) LNtGILNkHLQDLME K575-ac
TOP1 (mouse) LNTGILNKHLQDLME K577
TOP1 (rat) LNTGILNKHLQDLME K577
TOP1 (cow) LNTGILNKHLQDLME K579
K575-ub
LNtGILNkHLQDLME
0 2
TOP1 (human) LNtGILNkHLQDLME K575-ub
TOP1 (mouse) LNTGILNKHLQDLME K577
TOP1 (rat) LNTGILNKHLQDLME K577
TOP1 (cow) LNTGILNKHLQDLME K579
K587-ub
LMEGLTAkVFRtyNA
0 2
TOP1 (human) LMEGLTAkVFRtyNA K587-ub
TOP1 (mouse) LMEGLTAKVFRTYNA K589
TOP1 (rat) LMEGLTAKVFRTYNA K589
TOP1 (cow) LMEGLTAKVFRTYNA K591
T591-p
LTAkVFRtyNASITL
0 1
TOP1 (human) LTAkVFRtyNASITL T591-p
TOP1 (mouse) LTAKVFRTYNASITL T593
TOP1 (rat) LTAKVFRTYNASITL T593
TOP1 (cow) LTAKVFRTYNASITL T595
Y592-p
TAkVFRtyNASITLQ
0 1
TOP1 (human) TAkVFRtyNASITLQ Y592-p
TOP1 (mouse) TAKVFRTYNASITLQ Y594
TOP1 (rat) TAKVFRTYNASITLQ Y594
TOP1 (cow) TAKVFRTYNASITLQ Y596
K603-ub
ITLQQQLkELTAPDE
0 2
TOP1 (human) ITLQQQLkELTAPDE K603-ub
TOP1 (mouse) ITLQQQLKELTAPDE K605
TOP1 (rat) ITLQQQLKELTAPDE K605
TOP1 (cow) ITLQQQLKELTAPDE K607
K615
PDENIPAKILSYNRA
0 1
TOP1 (human) PDENIPAKILSYNRA K615
TOP1 (mouse) PDENVPAKILSYNRA K617
TOP1 (rat) PDENVPAkILSYNRA K617-ac
TOP1 (cow) PDENIPAKILSYNRA K619
K615-ub
PDENIPAkILSYNRA
0 4
TOP1 (human) PDENIPAkILSYNRA K615-ub
TOP1 (mouse) PDENVPAKILSYNRA K617
TOP1 (rat) PDENVPAKILSYNRA K617
TOP1 (cow) PDENIPAKILSYNRA K619
K642-ac
APPKTFEkSMMNLQt
0 1
TOP1 (human) APPKTFEkSMMNLQt K642-ac
TOP1 (mouse) APPKTFEKSMMNLQS K644
TOP1 (rat) APPKTFEKSMMNLQS K644
TOP1 (cow) APPKTFEKSMMNLQS K646
K642-ub
APPKTFEkSMMNLQt
0 6
TOP1 (human) APPKTFEkSMMNLQt K642-ub
TOP1 (mouse) APPKTFEKSMMNLQS K644
TOP1 (rat) APPKTFEKSMMNLQS K644
TOP1 (cow) APPKTFEKSMMNLQS K646
T649-p
kSMMNLQtKIDAKKE
0 1
TOP1 (human) kSMMNLQtKIDAKKE T649-p
TOP1 (mouse) KSMMNLQSKIDAKKD S651
TOP1 (rat) KSMMNLQSKIDAKKD S651
TOP1 (cow) KSMMNLQSKIDAKKE S653
K666-ub
ADARRDLkSAKADAK
0 1
TOP1 (human) ADARRDLkSAKADAK K666-ub
TOP1 (mouse) ADARRDLKSAKADAK K668
TOP1 (rat) ADARKDLKSAKADAK K668
TOP1 (cow) ADARRDLKSAKADAK K670
K676
KADAKVMKDAKTKKV
0 1
TOP1 (human) KADAKVMKDAKTKKV K676
TOP1 (mouse) KADAKVMKDAKTKKV K678
TOP1 (rat) KADAKVMkDAKTKKV K678-ub
TOP1 (cow) KADAKVLKDAKTKKV K680
K688-ub
KKVVESKkkAVQRLE
0 2
TOP1 (human) KKVVESKkkAVQRLE K688-ub
TOP1 (mouse) KKVVESKKKAVQRLE K690
TOP1 (rat) KKVVESKKKAVQRLE K690
TOP1 (cow) KKVVESKKKAVQRLE K692
K689-ub
KVVESKkkAVQRLEE
0 2
TOP1 (human) KVVESKkkAVQRLEE K689-ub
TOP1 (mouse) KVVESKKKAVQRLEE K691
TOP1 (rat) KVVESKKKAVQRLEE K691
TOP1 (cow) KVVESKKKAVQRLEE K693
T706-p
MKLEVQAtDREENkQ
0 1
TOP1 (human) MKLEVQAtDREENkQ T706-p
TOP1 (mouse) MKLEVQATDREENkQ T708
TOP1 (rat) MKLEVQATDREENKQ T708
TOP1 (cow) MKLEVQATDREENKQ T710
K712-ac
AtDREENkQIALGTS
0 37
TOP1 (human) AtDREENkQIALGTS K712-ac
TOP1 (mouse) ATDREENkQIALGTS K714-ac
TOP1 (rat) ATDREENKQIALGTS K714
TOP1 (cow) ATDREENKQIALGTS K716
K712-ub
AtDREENkQIALGTS
0 2
TOP1 (human) AtDREENkQIALGTS K712-ub
TOP1 (mouse) ATDREENKQIALGTS K714
TOP1 (rat) ATDREENKQIALGTS K714
TOP1 (cow) ATDREENKQIALGTS K716
Y723-p
LGTSKLNyLDPRITV
1 9
TOP1 (human) LGTSKLNyLDPRITV Y723-p
TOP1 (mouse) LGTSKLNyLDPRITV Y725-p
TOP1 (rat) LGTSKLNYLDPRITV Y725
TOP1 (cow) LGTSKLNYLDPRITV Y727
K742-ub
KWGVPIEkIYNKTQR
0 2
TOP1 (human) KWGVPIEkIYNKTQR K742-ub
TOP1 (mouse) KWGVPIEKIYNKTQR K744
TOP1 (rat) KWGVPIEKIYNKTQR K744
TOP1 (cow) KWGVPIEKIYNKTQR K746