Other Species / Isoforms
  TOPORS (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

 HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
S3-p
_____MGsQPPLGsP
0 1
TOPORS (human) _____MGsQPPLGsP S3-p
TOPORS (mouse) _____MGSQPPPPGs S3
TOPORS (rat) _____MGSQPPPLGS S3
S9-p
GsQPPLGsPLsREEG
0 7
TOPORS (human) GsQPPLGsPLsREEG S9-p
TOPORS (mouse) SQPPPPGsPLSREEG S10-p
TOPORS (rat) SQPPPLGSPLSREEG S10
S12-p
PPLGsPLsREEGEAP
Upstream
0 1
Treatment
  • nocodazole
TOPORS (human) PPLGsPLsREEGEAP S12-p
TOPORS (mouse) PPPGsPLSREEGEAP S13
TOPORS (rat) PPLGSPLSREEGEAP S13
R28-m1
PAPASEGrRRSRRVR
0 2
TOPORS (human) PAPASEGrRRSRRVR R28-m1
TOPORS (mouse) LVPAEEGRRRSRRVR R29
TOPORS (rat) LAPAEEGRRRSRRVR R29
S45-p
GSCRHRPsFLGCREL
Upstream
0 4
Treatment
  • ischemia
TOPORS (human) GSCRHRPsFLGCREL S45-p
TOPORS (mouse) GSCRHRPSLLSRREL S46
TOPORS (rat) GSCRHRPSLLGRREL S46
K73-ub
EIMASAAkEFkMDNF
0 5
TOPORS (human) EIMASAAkEFkMDNF K73-ub
TOPORS (mouse) EIMASAAkEFKMDNF K74-ub
TOPORS (rat) EIMASAAKEFKMDNF K74
K76-ub
ASAAkEFkMDNFsPk
0 3
TOPORS (human) ASAAkEFkMDNFsPk K76-ub
TOPORS (mouse) ASAAkEFKMDNFsPK K77
TOPORS (rat) ASAAKEFKMDNFsPK K77
K76-sm
ASAAkEFkMDNFsPk
0 1
TOPORS (human) ASAAkEFkMDNFsPk K76-sm
TOPORS (mouse) ASAAkEFKMDNFsPK K77
TOPORS (rat) ASAAKEFKMDNFsPK K77
S81-p
EFkMDNFsPkAGTSk
0 10
TOPORS (human) EFkMDNFsPkAGTSk S81-p
TOPORS (mouse) EFKMDNFsPKAGTSK S82-p
TOPORS (rat) EFKMDNFsPKAGTSK S82-p
K83-ub
kMDNFsPkAGTSkLQ
0 3
TOPORS (human) kMDNFsPkAGTSkLQ K83-ub
TOPORS (mouse) KMDNFsPKAGTSKLQ K84
TOPORS (rat) KMDNFsPKAGTSKLQ K84
K83-sm
kMDNFsPkAGTSkLQ
0 1
TOPORS (human) kMDNFsPkAGTSkLQ K83-sm
TOPORS (mouse) KMDNFsPKAGTSKLQ K84
TOPORS (rat) KMDNFsPKAGTSKLQ K84
K88-ub
sPkAGTSkLQQTVPA
0 3
TOPORS (human) sPkAGTSkLQQTVPA K88-ub
TOPORS (mouse) sPKAGTSKLQQTVPA K89
TOPORS (rat) sPKAGTSKLQQTVPA K89
K88-sm
sPkAGTSkLQQTVPA
0 1
TOPORS (human) sPkAGTSkLQQTVPA K88-sm
TOPORS (mouse) sPKAGTSKLQQTVPA K89
TOPORS (rat) sPKAGTSKLQQTVPA K89
S98-p
QTVPADAsPDskCPI
Upstream
Downstream
2 49
Effects on Modified Protein
  • enzymatic activity, altered
  • enzymatic activity, induced
  • molecular association, regulation
  • protein degradation
  • ubiquitination
Treatment
  • ZK-Thiazolidinone
TOPORS (human) QTVPADAsPDskCPI S98-p
TOPORS (mouse) QTVPADAsPDsKCPI S99-p
TOPORS (rat) QTVPADAsPDSKCPI S99-p
S101-p
PADAsPDskCPICLD
0 2
TOPORS (human) PADAsPDskCPICLD S101-p
TOPORS (mouse) PADAsPDsKCPICLD S102-p
TOPORS (rat) PADAsPDSKCPICLD S102
K102-ub
ADAsPDskCPICLDR
0 1
TOPORS (human) ADAsPDskCPICLDR K102-ub
TOPORS (mouse) ADAsPDsKCPICLDR K103
TOPORS (rat) ADAsPDSKCPICLDR K103
K122-ub
YLDRCLHkFCFRCVQ
0 1
TOPORS (human) YLDRCLHkFCFRCVQ K122-ub
TOPORS (mouse) YLDRCLHKFCFRCVQ K123
TOPORS (rat) YLDRCLHKFCFRCVQ K123
K135-ub
VQEWSKNkAECPLCK
0 2
TOPORS (human) VQEWSKNkAECPLCK K135-ub
TOPORS (mouse) VQEWSKNKAECPLCK K136
TOPORS (rat) VQEWSKNKAECPLCK K136
T173-p
SYNGSFVtPDRRFRy
0 21
TOPORS (human) SYNGSFVtPDRRFRy T173-p
TOPORS (mouse) SYNGSFTNPEVRRFR N174
TOPORS (rat) SYNGSFTAPEVRRFR A174
Y180-p
tPDRRFRyRTtLTRE
0 1
TOPORS (human) tPDRRFRyRTtLTRE Y180-p
TOPORS (mouse) PEVRRFRYRTTMTRE Y182
TOPORS (rat) PEVRRFRYRTTMTRE Y182
T183-p
RRFRyRTtLTRERNA
0 2
TOPORS (human) RRFRyRTtLTRERNA T183-p
TOPORS (mouse) RRFRYRTTMTRERSA T185
TOPORS (rat) RRFRYRTTMTRERNA T185
S191-p
LTRERNAsVysPsGP
0 2
TOPORS (human) LTRERNAsVysPsGP S191-p
TOPORS (mouse) MTRERSASLYsPSST S193
TOPORS (rat) MTRERNASLYSPSST S193
Y193-p
RERNAsVysPsGPVN
0 1
TOPORS (human) RERNAsVysPsGPVN Y193-p
TOPORS (mouse) RERSASLYsPSSTVS Y195
TOPORS (rat) RERNASLYSPSSTVS Y195
S194-p
ERNAsVysPsGPVNR
0 14
TOPORS (human) ERNAsVysPsGPVNR S194-p
TOPORS (mouse) ERSASLYsPSSTVSR S196-p
TOPORS (rat) ERNASLYSPSSTVSR S196
S196-p
NAsVysPsGPVNRRT
0 3
TOPORS (human) NAsVysPsGPVNRRT S196-p
TOPORS (mouse) SASLYsPSSTVSRRT S198
TOPORS (rat) NASLYSPSSTVSRRT S198
T204-p
GPVNRRTttPPDSGV
0 1
TOPORS (human) GPVNRRTttPPDSGV T204-p
TOPORS (mouse) STVSRRTTtPPDSGV T206
TOPORS (rat) STVSRRTSTPPDSGV S206
T205-p
PVNRRTttPPDSGVL
0 6
TOPORS (human) PVNRRTttPPDSGVL T205-p
TOPORS (mouse) TVSRRTTtPPDSGVL T207-p
TOPORS (rat) TVSRRTSTPPDSGVL T207
K249-ub
ADERSLRkIQEQDII
0 24
TOPORS (human) ADERSLRkIQEQDII K249-ub
TOPORS (mouse) TDERSLRkIQEQDII K251-ub
TOPORS (rat) TDERSLRKVQEQDII K251
K249-sm
ADERSLRkIQEQDII
0 1
TOPORS (human) ADERSLRkIQEQDII K249-sm
TOPORS (mouse) TDERSLRKIQEQDII K251
TOPORS (rat) TDERSLRKVQEQDII K251
Y263-p
INFRRTLyRAGARVR
0 1
TOPORS (human) INFRRTLyRAGARVR Y263-p
TOPORS (mouse) INFRRTLYRAGVRVR Y265
TOPORS (rat) INFRRTLYRAGVRVR Y265
S333
VTRYDLESQAFVSDL
0 1
TOPORS (human) VTRYDLESQAFVSDL S333
TOPORS (mouse) VTRYDLEsQAFVsDL S335-p
TOPORS (rat) VTRYDLESQAFVSDL S335
S338
LESQAFVSDLRPFLL
0 1
TOPORS (human) LESQAFVSDLRPFLL S338
TOPORS (mouse) LEsQAFVsDLRPFLL S340-p
TOPORS (rat) LESQAFVSDLRPFLL S340
T491-p
VKPLAERtPELVELs
0 5
TOPORS (human) VKPLAERtPELVELs T491-p
TOPORS (mouse) VKPLAERtPELVELs T492-p
TOPORS (rat) VKPLAERTPELVELS T492
S498-p
tPELVELssDsEDLG
0 4
TOPORS (human) tPELVELssDsEDLG S498-p
TOPORS (mouse) tPELVELssDsEELG S499-p
TOPORS (rat) TPELVELSSDSEELG S499
S499-p
PELVELssDsEDLGS
0 3
TOPORS (human) PELVELssDsEDLGS S499-p
TOPORS (mouse) PELVELssDsEELGP S500-p
TOPORS (rat) PELVELSSDSEELGS S500
S501-p
LVELssDsEDLGSYE
0 3
TOPORS (human) LVELssDsEDLGSYE S501-p
TOPORS (mouse) LVELssDsEELGPYE S502-p
TOPORS (rat) LVELSSDSEELGSYE S502
T515
EKMETVKTQEQEQSY
0 1
TOPORS (human) EKMETVKTQEQEQSY T515
TOPORS (mouse) EKVETVKtQEQEQSY T516-p
TOPORS (rat) EKMETVKTQEQEQSY T516
S533-p
DSDVSRCssPHsVLG
0 1
TOPORS (human) DSDVSRCssPHsVLG S533-p
TOPORS (mouse) DSDVSRASSPRSVLG S534
TOPORS (rat) DSDASRASSPRSVLG S534
S534-p
SDVSRCssPHsVLGK
0 1
TOPORS (human) SDVSRCssPHsVLGK S534-p
TOPORS (mouse) SDVSRASSPRSVLGK S535
TOPORS (rat) SDASRASSPRSVLGK S535
S537-p
SRCssPHsVLGKDEQ
0 1
TOPORS (human) SRCssPHsVLGKDEQ S537-p
TOPORS (mouse) SRASSPRSVLGKDEQ S538
TOPORS (rat) SRASSPRSVLGKDEQ S538
K547-ub
GKDEQINkGHCDSST
0 1
TOPORS (human) GKDEQINkGHCDSST K547-ub
TOPORS (mouse) GKDEQMSKSHCDSDT K548
TOPORS (rat) GKDEQMGKSHCDSDT K548
K547-sm
GKDEQINkGHCDSST
0 1
TOPORS (human) GKDEQINkGHCDSST K547-sm
TOPORS (mouse) GKDEQMSKSHCDSDT K548
TOPORS (rat) GKDEQMGKSHCDSDT K548
K557-ac
CDSSTRIkSkkEEKR
0 1
TOPORS (human) CDSSTRIkSkkEEKR K557-ac
TOPORS (mouse) CDSDTRISSKKEEKR S558
TOPORS (rat) CDSDTRINSKKEEKR N558
K559-ac
SSTRIkSkkEEKRST
0 1
TOPORS (human) SSTRIkSkkEEKRST K559-ac
TOPORS (mouse) SDTRISSKKEEKRST K560
TOPORS (rat) SDTRINSKKEEKRST K560
K560-ac
STRIkSkkEEKRSTs
0 1
TOPORS (human) STRIkSkkEEKRSTs K560-ac
TOPORS (mouse) DTRISSKKEEKRSTs K561
TOPORS (rat) DTRINSKKEEKRSTs K561
K560-sm
STRIkSkkEEKRSTs
1 0
TOPORS (human) STRIkSkkEEKRSTs K560-sm
TOPORS (mouse) DTRISSKKEEKRSTs K561
TOPORS (rat) DTRINSKKEEKRSTs K561
S567-p
kEEKRSTsLSsPrNL
0 6
TOPORS (human) kEEKRSTsLSsPrNL S567-p
TOPORS (mouse) KEEKRSTsLPAPRDS S568-p
TOPORS (rat) KEEKRSTsLSTPRDS S568-p
S570-p
KRSTsLSsPrNLNss
0 2
TOPORS (human) KRSTsLSsPrNLNss S570-p
TOPORS (mouse) KRSTsLPAPRDSsST A571
TOPORS (rat) KRSTsLSTPRDSSST T571
R572-m2
STsLSsPrNLNssVr
0 1
TOPORS (human) STsLSsPrNLNssVr R572-m2
TOPORS (mouse) STsLPAPRDSsSTRG R573
TOPORS (rat) STsLSTPRDSSSTRG R573
S576-p
SsPrNLNssVrGDrV
0 2
TOPORS (human) SsPrNLNssVrGDrV S576-p
TOPORS (mouse) LPAPRDSsSTRGDRV S576-p
TOPORS (rat) LSTPRDSSSTRGDRA S576
S577-p
sPrNLNssVrGDrVy
0 1
TOPORS (human) sPrNLNssVrGDrVy S577-p
TOPORS (mouse) PAPRDSsSTRGDRVC S577
TOPORS (rat) STPRDSSSTRGDRAC S577
R579-m2
rNLNssVrGDrVysP
0 1
TOPORS (human) rNLNssVrGDrVysP R579-m2
TOPORS (mouse) PRDSsSTRGDRVCsP R579
TOPORS (rat) PRDSSSTRGDRACSP R579
R582-m2
NssVrGDrVysPyNH
0 1
TOPORS (human) NssVrGDrVysPyNH R582-m2
TOPORS (mouse) SsSTRGDRVCsPYNH R582
TOPORS (rat) SSSTRGDRACSPYNH R582
Y584-p
sVrGDrVysPyNHRH
0 2
TOPORS (human) sVrGDrVysPyNHRH Y584-p
TOPORS (mouse) STRGDRVCsPYNHRH C584
TOPORS (rat) STRGDRACSPYNHRH C584
S585-p
VrGDrVysPyNHRHR
0 42
TOPORS (human) VrGDrVysPyNHRHR S585-p
TOPORS (mouse) TRGDRVCsPYNHRHR S585-p
TOPORS (rat) TRGDRACSPYNHRHR S585
Y587-p
GDrVysPyNHRHRKR
0 3
TOPORS (human) GDrVysPyNHRHRKR Y587-p
TOPORS (mouse) GDRVCsPYNHRHRKG Y587
TOPORS (rat) GDRACSPYNHRHRKG Y587
T667
LSLSSESTSRSRSRS
0 1
TOPORS (human) LSLSSESTSRSRSRS T667
TOPORS (mouse) LSLSSGStsRSrSRS T667-p
TOPORS (rat) LSLSSGSTSRSRSRS T668
S668
SLSSESTSRSRSRSS
0 1
TOPORS (human) SLSSESTSRSRSRSS S668
TOPORS (mouse) SLSSGStsRSrSRSS S668-p
TOPORS (rat) SLSSGSTSRSRSRSS S669
R671
SESTSRSRSRSSDHG
0 1
TOPORS (human) SESTSRSRSRSSDHG R671
TOPORS (mouse) SGStsRSrSRSSDHG R671-m1
TOPORS (rat) SGSTSRSRSRSSDHG R672
K679-ac
SRSSDHGkRRSRSRN
0 1
TOPORS (human) SRSSDHGkRRSRSRN K679-ac
TOPORS (mouse) SRSSDHGKRRSRSRN K679
TOPORS (rat) SRSSDHGKRRSRSRN K680
K701-sm
NNYGSRYkWEYTYys
0 1
TOPORS (human) NNYGSRYkWEYTYys K701-sm
TOPORS (mouse) NNYGSKYKWEYTYYS K701
TOPORS (rat) NNYGSKYKWEYTYYS K702
Y707-p
YkWEYTYysRNkDRD
0 1
TOPORS (human) YkWEYTYysRNkDRD Y707-p
TOPORS (mouse) YKWEYTYYSRNKDRD Y707
TOPORS (rat) YKWEYTYYSRNKDRD Y708
S708-p
kWEYTYysRNkDRDG
0 1
TOPORS (human) kWEYTYysRNkDRDG S708-p
TOPORS (mouse) KWEYTYYSRNKDRDG S708
TOPORS (rat) KWEYTYYSRNKDRDG S709
K711-ub
YTYysRNkDRDGYEs
0 3
TOPORS (human) YTYysRNkDRDGYEs K711-ub
TOPORS (mouse) YTYYSRNKDRDGYEs K711
TOPORS (rat) YTYYSRNKDRDGYES K712
K711-sm
YTYysRNkDRDGYEs
0 1
TOPORS (human) YTYysRNkDRDGYEs K711-sm
TOPORS (mouse) YTYYSRNKDRDGYEs K711
TOPORS (rat) YTYYSRNKDRDGYES K712
S718-p
kDRDGYEsSYRRRTL
Upstream
Downstream
3 2
Effects on Modified Protein
  • enzymatic activity, altered
  • protein degradation
  • sumoylation
  • ubiquitination
Effects on Biological Processes:
  • cell cycle regulation
Kinase, in vitro:
  • PLK1 (human)
Putative in vivo kinases:
  • PLK1 (human)
Treatment
  • BTO-1
  • siRNA
TOPORS (human) kDRDGYEsSYRRRTL S718-p
TOPORS (mouse) KDRDGYEsSYRRRTL S718-p
TOPORS (rat) KDRDGYESSYRRRTL S719
S731-p
TLSRAHYsRQsssPE
0 1
TOPORS (human) TLSRAHYsRQsssPE S731-p
TOPORS (mouse) TLSRAHYSRQsssPE S731
TOPORS (rat) TLSRAHYSRQSSSPE S732
S734-p
RAHYsRQsssPEFRV
0 11
TOPORS (human) RAHYsRQsssPEFRV S734-p
TOPORS (mouse) RAHYSRQsssPEFRI S734-p
TOPORS (rat) RAHYSRQSSSPEFRI S735
S735-p
AHYsRQsssPEFRVQ
0 13
TOPORS (human) AHYsRQsssPEFRVQ S735-p
TOPORS (mouse) AHYSRQsssPEFRIQ S735-p
TOPORS (rat) AHYSRQSSSPEFRIQ S736
S736-p
HYsRQsssPEFRVQS
0 13
TOPORS (human) HYsRQsssPEFRVQS S736-p
TOPORS (mouse) HYSRQsssPEFRIQS S736-p
TOPORS (rat) HYSRQSSSPEFRIQS S737
K760-ub
KNNHSERkYYYYERH
0 3
TOPORS (human) KNNHSERkYYYYERH K760-ub
TOPORS (mouse) KKNHSERkYYYYERR K759-ub
TOPORS (rat) RKNHSERKYYYYERH K760
S781-p
SNRSRTAsTGtDRVR
0 1
TOPORS (human) SNRSRTAsTGtDRVR S781-p
TOPORS (mouse) SNRSRTTSAGPDRVR S780
TOPORS (rat) SNRSRTTSAVPDRMR S781
T784-p
SRTAsTGtDRVRNEk
0 2
TOPORS (human) SRTAsTGtDRVRNEk T784-p
TOPORS (mouse) SRTTSAGPDRVRNEK P783
TOPORS (rat) SRTTSAVPDRMRNEK P784
K791-ub
tDRVRNEkPGGKRKY
0 1
TOPORS (human) tDRVRNEkPGGKRKY K791-ub
TOPORS (mouse) PDRVRNEKPGGKRKY K790
TOPORS (rat) PDRMRNEKPGGKRKY K791
K799-ub
PGGKRKYkTRHLEGT
0 1
TOPORS (human) PGGKRKYkTRHLEGT K799-ub
TOPORS (mouse) PGGKRKYKTRHLEGT K798
TOPORS (rat) PGGKRKYKTRHLEDT K799
K819-ub
PSREFASkAkDSHYQ
0 1
TOPORS (human) PSREFASkAkDSHYQ K819-ub
TOPORS (mouse) PAREFTSKGKDSHYQ K818
TOPORS (rat) PSRAFASRVKESHYQ R819
K821-ub
REFASkAkDSHYQkS
0 1
TOPORS (human) REFASkAkDSHYQkS K821-ub
TOPORS (mouse) REFTSKGKDSHYQKS K820
TOPORS (rat) RAFASRVKESHYQKP K821
K827-ub
AkDSHYQkSSSkLDG
0 1
TOPORS (human) AkDSHYQkSSSkLDG K827-ub
TOPORS (mouse) GKDSHYQKSKLDGSY K826
TOPORS (rat) VKESHYQKPSKLDGG K827
K831-ub
HYQkSSSkLDGNYKN
0 2
TOPORS (human) HYQkSSSkLDGNYKN K831-ub
TOPORS (mouse) DSHYQKSKLDGSYKN K828
TOPORS (rat) SHYQKPSKLDGGSKD K830
T862-p
HKRRKRKtRsLsVEI
0 6
TOPORS (human) HKRRKRKtRsLsVEI T862-p
TOPORS (mouse) HKRRRRRtRsLsVEI T859-p
TOPORS (rat) HKRRKRRARSLSVEI A861
S864-p
RRKRKtRsLsVEIVY
0 13
TOPORS (human) RRKRKtRsLsVEIVY S864-p
TOPORS (mouse) RRRRRtRsLsVEIVY S861-p
TOPORS (rat) RRKRRARSLSVEIVY S863
S866-p
KRKtRsLsVEIVYEG
0 13
TOPORS (human) KRKtRsLsVEIVYEG S866-p
TOPORS (mouse) RRRtRsLsVEIVYEG S863-p
TOPORS (rat) KRRARSLSVEIVYEG S865
S904
HGDNASRSPVVITID
0 3
TOPORS (human) HGDNASRSPVVITID S904
TOPORS (mouse) HGDNTSRsPVVITID S901-p
TOPORS (rat) HGDNTSRsPVVITID S903-p
S912-p
PVVITIDsDsDKDSE
0 10
TOPORS (human) PVVITIDsDsDKDSE S912-p
TOPORS (mouse) PVVITIDsDsDGESE S909-p
TOPORS (rat) PVVITIDsDsDGDAG S911-p
S914-p
VITIDsDsDKDSEVK
0 11
TOPORS (human) VITIDsDsDKDSEVK S914-p
TOPORS (mouse) VITIDsDsDGESEVK S911-p
TOPORS (rat) VITIDsDsDGDAGVK S913-p
N1010
TFVSDLENQPSNIVS
0 1
TOPORS (human) TFVSDLENQPSNIVS N1010
TOPORS (mouse) TFASDLEsQSSNVsI S999-p
TOPORS (rat) TFASDVESQSSNASI S1008
S1017
NQPSNIVSLQTEPSR
0 1
TOPORS (human) NQPSNIVSLQTEPSR S1017
TOPORS (mouse) EsQSSNVsIQAEPSR S1005-p
TOPORS (rat) ESQSSNASIPTEPSR S1014
S1028-p
EPSRQLPsPRTSLMS
0 8
TOPORS (human) EPSRQLPsPRTSLMS S1028-p
TOPORS (mouse) EPSRPVPsPRTSLSS S1016-p
TOPORS (rat) EPSRPLPsPRTSLSS S1025-p
C1037
RTSLMSVCLGRDCDM
0 11
TOPORS (human) RTSLMSVCLGRDCDM C1037
TOPORS (mouse) RTSLSSVsPGRDCDV S1025-p
TOPORS (rat) RTSLSSVSPGRDCDM S1034