Other Species / Isoforms
  PAK2 (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

 HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
S2
______MsDNGELED
Upstream
0 39
Treatment
  • angiotensin-(1-7)
  • dasatinib
  • LRRK2-IN-1
PAK2 (human) ______MsDNGELED S2
PAK2 (mouse) ______MsDNGELED S2
PAK2 (rat) ______MsDNGELED S2
PAK2 (rabbit) ______MSDNGELED S2
PAK2 (cow) ______MSDNGELED S2
S19
PAPPVRMsstIFstG
1 12
PAK2 (human) PAPPVRMsstIFstG S19
PAK2 (mouse) PAPPVRMSstIFSTG S19
PAK2 (rat) PAPPVRMSSTIFSTG S19
PAK2 (rabbit) PAPPVRMssTIFSTG S19
PAK2 (cow) PAPPVRMSSTIFSTG S19
S20
APPVRMsstIFstGG
Upstream
Downstream
8 111
PAK2 (human)
S20
PAK2 (rat)
S20
Effects on Biological Processes:
  • carcinogenesis, induced
  • cell growth, induced
Kinase, in vitro:
  • AMPKA2 (human)
Putative in vivo kinases:
  • AMPKA2 (human)
Regulatory protein:
  • CD44 (human)
Treatment
  • glucose_starvation
PAK2 (human) APPVRMsstIFstGG S20
PAK2 (mouse) APPVRMSstIFSTGG S20
PAK2 (rat) APPVRMSSTIFSTGG S20
PAK2 (rabbit) APPVRMssTIFSTGG S20
PAK2 (cow) APPVRMSSTIFSTGG S20
T21
PPVRMsstIFstGGK
0 13
PAK2 (human) PPVRMsstIFstGGK T21
PAK2 (mouse) PPVRMSstIFSTGGK T21
PAK2 (rat) PPVRMSSTIFSTGGK T21
PAK2 (rabbit) PPVRMssTIFSTGGK T21
PAK2 (cow) PPVRMSSTIFSTGGK T21
S24
RMsstIFstGGKDPL
0 1
PAK2 (human) RMsstIFstGGKDPL S24
PAK2 (mouse) RMSstIFSTGGKDPL S24
PAK2 (rat) RMSSTIFSTGGKDPL S24
PAK2 (rabbit) RMssTIFSTGGKDPL S24
PAK2 (cow) RMSSTIFSTGGKDPL S24
T25
MsstIFstGGKDPLs
0 1
PAK2 (human) MsstIFstGGKDPLs T25
PAK2 (mouse) MSstIFSTGGKDPLS T25
PAK2 (rat) MSSTIFSTGGKDPLS T25
PAK2 (rabbit) MssTIFSTGGKDPLS T25
PAK2 (cow) MSSTIFSTGGKDPLS T25
S32
tGGKDPLsANHsLKP
0 6
PAK2 (human) tGGKDPLsANHsLKP S32
PAK2 (mouse) TGGKDPLSANHsLKP S32
PAK2 (rat) TGGKDPLSANHSLKP S32
PAK2 (rabbit) TGGKDPLSANHSLKP S32
PAK2 (cow) TGGKDPLSANHSLKP S32
S36
DPLsANHsLKPLPsV
0 16
PAK2 (human) DPLsANHsLKPLPsV S36
PAK2 (mouse) DPLSANHsLKPLPsV S36
PAK2 (rat) DPLSANHSLKPLPSV S36
PAK2 (rabbit) DPLSANHSLKPLPSV S36
PAK2 (cow) DPLSANHSLKPLPSV S36
S42
HsLKPLPsVPEEKKP
0 27
PAK2 (human) HsLKPLPsVPEEKKP S42
PAK2 (mouse) HsLKPLPsVPEEKKP S42
PAK2 (rat) HSLKPLPSVPEEKKP S42
PAK2 (rabbit) HSLKPLPSVPEEKKP S42
PAK2 (cow) HSLKPLPSVPEEKKP S42
S55
KPRHKIIsIFsGtEK
2 15
PAK2 (human) KPRHKIIsIFsGtEK S55
PAK2 (mouse) KPRNKIIsIFsGtEK S55
PAK2 (rat) KPRNKIISIFSsTEK S55
PAK2 (rabbit) KPRNKIIsIFSGTEK S55
PAK2 (cow) KPRNKIISIFSSTEK S55
S58
HKIIsIFsGtEKGsK
Upstream
0 17
Treatment
  • antibody
  • ischemia
PAK2 (human) HKIIsIFsGtEKGsK S58
PAK2 (mouse) NKIIsIFsGtEKGsK S58
PAK2 (rat) NKIISIFSsTEKGSK S58
PAK2 (rabbit) NKIIsIFSGTEKGSK S58
PAK2 (cow) NKIISIFSSTEKGSK S58
G59
KIIsIFsGtEKGsKK
0 1
PAK2 (human) KIIsIFsGtEKGsKK G59
PAK2 (mouse) KIIsIFsGtEKGsKK G59
PAK2 (rat) KIISIFSsTEKGSKK S59
PAK2 (rabbit) KIIsIFSGTEKGSKK G59
PAK2 (cow) KIISIFSSTEKGSKK S59
T60
IIsIFsGtEKGsKKK
0 6
PAK2 (human) IIsIFsGtEKGsKKK T60
PAK2 (mouse) IIsIFsGtEKGsKKK T60
PAK2 (rat) IISIFSsTEKGSKKK T60
PAK2 (rabbit) IIsIFSGTEKGSKKK T60
PAK2 (cow) IISIFSSTEKGSKKK T60
S64
FsGtEKGsKKKEKER
Upstream
Downstream
1 9
Effects on Biological Processes:
  • carcinogenesis, inhibited
  • signaling pathway regulation
Regulatory protein:
  • CD28 (human)
  • CD3Z (human)
Treatment
  • LRRK2-IN-1
PAK2 (human) FsGtEKGsKKKEKER S64
PAK2 (mouse) FsGtEKGsKKKEKER S64
PAK2 (rat) FSsTEKGSKKKEKER S64
PAK2 (rabbit) FSGTEKGSKKKEKER S64
PAK2 (cow) FSSTEKGSKKKEKER S64
S75
EKERPEIsPPSDFEH
0 3
PAK2 (human) EKERPEIsPPSDFEH S75
PAK2 (mouse) EKERPEISPPsDFEH S75
PAK2 (rat) EKERPEISPPSDFEH S75
PAK2 (rabbit) EKERPEISPPSDFEH S75
PAK2 (cow) EKERPEISPPSDFEH S75
S78
RPEIsPPSDFEHTIH
0 1
PAK2 (human) RPEIsPPSDFEHTIH S78
PAK2 (mouse) RPEISPPsDFEHTIH S78
PAK2 (rat) RPEISPPSDFEHTIH S78
PAK2 (rabbit) RPEISPPSDFEHTIH S78
PAK2 (cow) RPEISPPSDFEHTIH S78
Y130
VLDVLKFyDsNtVKQ
Upstream
Downstream
2 128
Effects on Modified Protein
  • enzymatic activity, induced
Phosphatases, in vitro:
  • PTP1B (human)
Treatment
  • vanadate
PAK2 (human) VLDVLKFyDsNtVKQ Y130
PAK2 (mouse) VLDVLKFYDsNTVKQ Y130
PAK2 (rat) VLDVLKFYDsNTVKQ Y130
PAK2 (rabbit) VLDVLKFYDSNTVKQ Y130
PAK2 (cow) VLDVLKFYDSNTVKQ Y130
S132
DVLKFyDsNtVKQKy
0 19
PAK2 (human) DVLKFyDsNtVKQKy S132
PAK2 (mouse) DVLKFYDsNTVKQKy S132
PAK2 (rat) DVLKFYDsNTVKQKy S132
PAK2 (rabbit) DVLKFYDSNTVKQKY S132
PAK2 (cow) DVLKFYDSNTVKQKY S132
T134
LKFyDsNtVKQKyLs
Upstream
Downstream
1 13
Effects on Modified Protein
  • phosphorylation
Effects on Biological Processes:
  • carcinogenesis, induced
  • cell cycle regulation
  • cell growth, induced
  • signaling pathway regulation
Kinase, in vitro:
  • CDK12 (human)
Putative in vivo kinases:
  • CDK12 (human)
Treatment
  • siRNA
PAK2 (human) LKFyDsNtVKQKyLs T134
PAK2 (mouse) LKFYDsNTVKQKyLs T134
PAK2 (rat) LKFYDsNTVKQKyLs T134
PAK2 (rabbit) LKFYDSNTVKQKYLs T134
PAK2 (cow) LKFYDSNTVKQKYLS T134
Y139
sNtVKQKyLsFtPPE
Upstream
Downstream
2 41
Effects on Modified Protein
  • enzymatic activity, induced
Treatment
  • vanadate
PAK2 (human) sNtVKQKyLsFtPPE Y139
PAK2 (mouse) sNTVKQKyLsFtPPE Y139
PAK2 (rat) sNTVKQKyLsFtPPE Y139
PAK2 (rabbit) SNTVKQKYLsFTPPE Y139
PAK2 (cow) SNTVKQKYLSFTPPE Y139
S141
tVKQKyLsFtPPEKD
Upstream
Downstream
13 157
PAK2 (human)
S141
PAK2 (mouse)
S141
PAK2 (rat)
S141
Effects on Modified Protein
  • enzymatic activity, induced
Kinase, in vitro:
  • PAK2 (human)
Regulatory protein:
  • AFAP1L1 (human)
  • CSK (human)
  • PRP4 (human)
Treatment
  • dasatinib
  • EGF
  • faslodex
  • IPA-3
  • ischemia
  • nocodazole
  • saracatinib
  • tamoxifen
  • U0126
  • vanadate
PAK2 (human) tVKQKyLsFtPPEKD S141
PAK2 (mouse) TVKQKyLsFtPPEKD S141
PAK2 (rat) TVKQKyLsFtPPEKD S141
PAK2 (rabbit) TVKQKYLsFTPPEKD S141
PAK2 (cow) TVKQKYLSFTPPEKD S141
T143
KQKyLsFtPPEKDGF
Upstream
0 56
Treatment
  • antibody
  • ischemia
PAK2 (human) KQKyLsFtPPEKDGF T143
PAK2 (mouse) KQKyLsFtPPEKDGF T143
PAK2 (rat) KQKyLsFtPPEKDGF T143
PAK2 (rabbit) KQKYLsFTPPEKDGF T143
PAK2 (cow) KQKYLSFTPPEKDGF T143
S152
PEKDGFPsGtPALNA
0 21
PAK2 (human) PEKDGFPsGtPALNA S152
PAK2 (mouse) PEKDGFPsGtPALNt S152
PAK2 (rat) PEKDGFPsGtPALNT S152
PAK2 (rabbit) PEKDGFPSGAPALNT S152
PAK2 (cow) PEKDGFPSGTPALNT S152
T154
KDGFPsGtPALNAKG
Upstream
0 20
Treatment
  • antibody
PAK2 (human) KDGFPsGtPALNAKG T154
PAK2 (mouse) KDGFPsGtPALNtKG T154
PAK2 (rat) KDGFPsGtPALNTKG T154
PAK2 (rabbit) KDGFPSGAPALNTKV A154
PAK2 (cow) KDGFPSGTPALNTKG T154
A159
sGtPALNAKGTEAPA
0 4
PAK2 (human) sGtPALNAKGTEAPA A159
PAK2 (mouse) sGtPALNtKGsETSA T159
PAK2 (rat) sGtPALNTKGSETSA T159
PAK2 (rabbit) SGAPALNTKVSETsA T159
PAK2 (cow) SGTPALNTKGSETSA T159
T162
PALNAKGTEAPAVVt
0 1
PAK2 (human) PALNAKGTEAPAVVt T162
PAK2 (mouse) PALNtKGsETSAVVt S162
PAK2 (rat) PALNTKGSETSAVVT S162
PAK2 (rabbit) PALNTKVSETsAVVT S162
PAK2 (cow) PALNTKGSETSAVVT S162
P165
NAKGTEAPAVVtEEE
1 0
PAK2 (human) NAKGTEAPAVVtEEE P165
PAK2 (mouse) NtKGsETSAVVtEED S165
PAK2 (rat) NTKGSETSAVVTEED S165
PAK2 (rabbit) NTKVSETsAVVTEED S165
PAK2 (cow) NTKGSETSAVVTEED S165
T169
TEAPAVVtEEEDDDE
Upstream
Downstream
1 43
Effects on Modified Protein
  • phosphorylation
Effects on Biological Processes:
  • carcinogenesis, induced
  • cell cycle regulation
  • cell growth, induced
  • signaling pathway regulation
Kinase, in vitro:
  • CDK12 (human)
Putative in vivo kinases:
  • CDK12 (human)
Treatment
  • ischemia
  • SII_angiotensin_2
  • siRNA
PAK2 (human) TEAPAVVtEEEDDDE T169
PAK2 (mouse) sETSAVVtEEDDDDE T169
PAK2 (rat) SETSAVVTEEDDDDE T169
PAK2 (rabbit) SETsAVVTEEDDDDE T169
PAK2 (cow) SETSAVVTEEDDDDE T169
T190
IAPRPDHtKsIytRs
0 1
PAK2 (human) IAPRPDHtKsIytRs T190
PAK2 (mouse) IAPRPDHTKsIYtRs T190
PAK2 (rat) IAPRPDHTKSIYTRs T190
PAK2 (rabbit) IAPRPDHTKsIYTRs T190
PAK2 (cow) IAPRPDHTKSIYTRS T190
S192
PRPDHtKsIytRsVI
Upstream
6 1
PAK2 (human)
S192
PAK2 (mouse)
S192
PAK2 (rat)
S192
Kinase, in vitro:
  • PAK2 (human)
Treatment
  • CXCL12
PAK2 (human) PRPDHtKsIytRsVI S192
PAK2 (mouse) PRPDHTKsIYtRsVI S192
PAK2 (rat) PRPDHTKSIYTRsVI S192
PAK2 (rabbit) PRPDHTKsIYTRsVI S192
PAK2 (cow) PRPDHTKSIYTRSVI S192
Y194
PDHtKsIytRsVIDP
Upstream
Downstream
2 18
Effects on Modified Protein
  • enzymatic activity, induced
Treatment
  • vanadate
PAK2 (human) PDHtKsIytRsVIDP Y194
PAK2 (mouse) PDHTKsIYtRsVIDP Y194
PAK2 (rat) PDHTKSIYTRsVIDP Y194
PAK2 (rabbit) PDHTKsIYTRsVIDP Y194
PAK2 (cow) PDHTKSIYTRSVIDP Y194
T195
DHtKsIytRsVIDPV
0 5
PAK2 (human) DHtKsIytRsVIDPV T195
PAK2 (mouse) DHTKsIYtRsVIDPI T195
PAK2 (rat) DHTKSIYTRsVIDPI T195
PAK2 (rabbit) DHTKsIYTRsVIDPI T195
PAK2 (cow) DHTKSIYTRSVIDPI T195
S197
tKsIytRsVIDPVPA
Upstream
7 34
PAK2 (human)
S197
PAK2 (mouse)
S197
PAK2 (rat)
S197
Kinase, in vitro:
  • PAK2 (human)
Treatment
  • antibody
  • CXCL12
PAK2 (human) tKsIytRsVIDPVPA S197
PAK2 (mouse) TKsIYtRsVIDPIPA S197
PAK2 (rat) TKSIYTRsVIDPIPA S197
PAK2 (rabbit) TKsIYTRsVIDPIPA S197
PAK2 (cow) TKSIYTRSVIDPIPA S197
G213
VGDSHVDGAAKsLDK
0 1
PAK2 (human) VGDSHVDGAAKsLDK G213
PAK2 (mouse) VGDSNVDsGAKSSDK S213
PAK2 (rat) VGDSNVDSGAKSSDK S213
PAK2 (rabbit) VGDSHVDSGAKSSDK S213
PAK2 (cow) VGDSNVDGGAKTSDK G213
S217
HVDGAAKsLDKQKKK
0 2
PAK2 (human) HVDGAAKsLDKQKKK S217
PAK2 (mouse) NVDsGAKSSDKQKKK S217
PAK2 (rat) NVDSGAKSSDKQKKK S217
PAK2 (rabbit) HVDSGAKSSDKQKKK S217
PAK2 (cow) NVDGGAKTSDKQKKK T217
T228
QKKKTKMtDEEIMEK
0 1
PAK2 (human) QKKKTKMtDEEIMEK T228
PAK2 (mouse) QKKKAKMTDEEIMEK T228
PAK2 (rat) QKKKAKMTDEEIMEK T228
PAK2 (rabbit) QKKKTKMTDEEIMEK T228
PAK2 (cow) QKKKAKMTDEEIMEK T228
Y252
PKKKYTRYEKIGQGA
0 2
PAK2 (human) PKKKYTRYEKIGQGA Y252
PAK2 (mouse) PKKKYTRyEKIGQGA Y252
PAK2 (rat) PKKKYTRYEKIGQGA Y252
PAK2 (rabbit) PKKKYTRYEKIGQGA Y252
PAK2 (cow) PKKKYTRYEKIGQGA Y252
S381
VLLGMEGsVKLTDFG
0 1
PAK2 (human) VLLGMEGsVKLTDFG S381
PAK2 (mouse) VLLGMEGSVKLTDFG S381
PAK2 (rat) VLLGMEGSVKLTDFG S381
PAK2 (rabbit) VLLGMEGSVKLTDFG S381
PAK2 (cow) VLLGMEGSVKLTDFG S381
T394
FGFCAQItPEQSKRs
0 2
PAK2 (human) FGFCAQItPEQSKRs T394
PAK2 (mouse) FGFCAQITPEQSKRs T394
PAK2 (rat) FGFCAQITPEQSKRs T394
PAK2 (rabbit) FGFCAQITPEQSKRS T394
PAK2 (cow) FGFCAQITPEQSKRS T394
S401
tPEQSKRstMVGtPY
0 5
PAK2 (human) tPEQSKRstMVGtPY S401
PAK2 (mouse) TPEQSKRstMVGtPY S401
PAK2 (rat) TPEQSKRstMVGTPY S401
PAK2 (rabbit) TPEQSKRStMVGTPY S401
PAK2 (cow) TPEQSKRSTMVGTPY S401
T402
PEQSKRstMVGtPYW
Upstream
Downstream
14 12
PAK2 (human)
T402
PAK2 (mouse)
T402
PAK2 (rat)
T402
Effects on Modified Protein
  • activity, induced
  • enzymatic activity, induced
  • protein conformation
Effects on Biological Processes:
  • cell cycle regulation
Kinase, in vitro:
  • PAK2 (human)
Treatment
  • antibody
PAK2 (human) PEQSKRstMVGtPYW T402
PAK2 (mouse) PEQSKRstMVGtPYW T402
PAK2 (rat) PEQSKRstMVGTPYW T402
PAK2 (rabbit) PEQSKRStMVGTPYW T402
PAK2 (cow) PEQSKRSTMVGTPYW T402
T406
KRstMVGtPYWMAPE
0 4
PAK2 (human) KRstMVGtPYWMAPE T406
PAK2 (mouse) KRstMVGtPYWMAPE T406
PAK2 (rat) KRstMVGTPYWMAPE T406
PAK2 (rabbit) KRStMVGTPYWMAPE T406
PAK2 (cow) KRSTMVGTPYWMAPE T406
Y453
ENPLRALyLIATNGT
0 15
PAK2 (human) ENPLRALyLIATNGT Y453
PAK2 (mouse) ENPLRALYLIATNGT Y453
PAK2 (rat) ENPLRALYLIATNGT Y453
PAK2 (rabbit) ENPLRALYLIATNGT Y453
PAK2 (cow) ENPLRALYLIATNGT Y453
S490
MDVEKRGsAKELLQH
0 3
PAK2 (human) MDVEKRGsAKELLQH S490
PAK2 (mouse) MDVEKRGsAKELLQH S490
PAK2 (rat) MDVEKRGSAKELLQH S490
PAK2 (rabbit) MDVEKRGSAKELLQH S490
PAK2 (cow) MDVEKRGSARELLQH S490
S507
LKLAKPLsSLTPLIM
0 1
PAK2 (human) LKLAKPLsSLTPLIM S507
PAK2 (mouse) LKLAKPLSSLTPLIL S507
PAK2 (rat) LKLAKPLSSLTPLIL S507
PAK2 (rabbit) LKLAKPLSSLTPLIM S507
PAK2 (cow) LKLAKPLSSLTPLIM S507