Other Species / Isoforms
  LEO1 (human)      LTP 

LTP (Low Throughput Papers) : The number of records in which this modification site was determined using methods other than discovery mass spectrometry.

  HTP 

HTP (High Throughput Papers): The number of records in which this modification site was assigned using ONLY proteomic discovery mass spectrometry.

 
S10-p
DMEDLFGsDADsEAE
Upstream
0 18
Regulatory protein:
  • PLK1 (human)
LEO1 (human) DMEDLFGsDADsEAE S10-p
LEO1 (mouse) DMEDLFGsEAEsEAE S10-p
LEO1 (rat) DMEDLFGsEAEsEAE S10-p
S14-p
LFGsDADsEAERKDS
Upstream
0 19
Regulatory protein:
  • PLK1 (human)
Treatment
  • dasatinib
LEO1 (human) LFGsDADsEAERKDS S14-p
LEO1 (mouse) LFGsEAEsEAERKDS S14-p
LEO1 (rat) LFGsEAEsEAERKDS S14-p
S27-p
DSDSGSDsDsDQENA
0 1
LEO1 (human) DSDSGSDsDsDQENA S27-p
LEO1 (mouse) DSESESDSDSDQDNG S27
LEO1 (rat) DSDSGSDSDSDQDNG S27
S29-p
DSGSDsDsDQENAAS
0 1
LEO1 (human) DSGSDsDsDQENAAS S29-p
LEO1 (mouse) ESESDSDSDQDNGAS S29
LEO1 (rat) DSGSDSDSDQDNGAS S29
S66-p
KELFGDDsEDEGAsH
0 11
LEO1 (human) KELFGDDsEDEGAsH S66-p
LEO1 (mouse) KELFGDDsEEEGAsH S66-p
LEO1 (rat) KELFGDDSEEEGAPH S66
S72-p
DsEDEGAsHHsGsDN
0 3
LEO1 (human) DsEDEGAsHHsGsDN S72-p
LEO1 (mouse) DsEEEGAsHHsGsDN S72-p
LEO1 (rat) DSEEEGAPHHSGSDN P72
S75-p
DEGAsHHsGsDNHsE
0 3
LEO1 (human) DEGAsHHsGsDNHsE S75-p
LEO1 (mouse) EEGAsHHsGsDNHsE S75-p
LEO1 (rat) EEGAPHHSGSDNHSE S75
S77-p
GAsHHsGsDNHsERS
0 2
LEO1 (human) GAsHHsGsDNHsERS S77-p
LEO1 (mouse) GAsHHsGsDNHsERS S77-p
LEO1 (rat) GAPHHSGSDNHSEQS S77
S81-p
HsGsDNHsERSDNRs
0 2
LEO1 (human) HsGsDNHsERSDNRs S81-p
LEO1 (mouse) HsGsDNHsERSDNRS S81-p
LEO1 (rat) HSGSDNHSEQSDNRS S81
S88-p
sERSDNRsEAsERSD
Upstream
Downstream
1 2
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
Effects on Biological Processes:
  • apoptosis, induced
  • carcinogenesis, inhibited
  • cell growth, inhibited
  • signaling pathway regulation
  • transcription, inhibited
Phosphatases, in vitro:
  • PTP4A3 (human)
Putative upstream phosphatases:
  • PTP4A3 (human)
Treatment
  • siRNA
LEO1 (human) sERSDNRsEAsERSD S88-p
LEO1 (mouse) sERSDNRSEASERSD S88
LEO1 (rat) SEQSDNRSEASEERS S88
S91-p
SDNRsEAsERSDHED
Upstream
Downstream
1 1
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
Effects on Biological Processes:
  • apoptosis, induced
  • carcinogenesis, inhibited
  • cell growth, inhibited
  • signaling pathway regulation
  • transcription, inhibited
Phosphatases, in vitro:
  • PTP4A3 (human)
Putative upstream phosphatases:
  • PTP4A3 (human)
Treatment
  • siRNA
LEO1 (human) SDNRsEAsERSDHED S91-p
LEO1 (mouse) SDNRSEASERSDHED S91
LEO1 (rat) SDNRSEASEERSDHE S91
S102-p
DHEDNDPsDVDQHsG
0 1
LEO1 (human) DHEDNDPsDVDQHsG S102-p
LEO1 (mouse) DHEDNEPSDEDQHSG S102
LEO1 (rat) DHEDNEPSDVDQHSG S103
S108-p
PsDVDQHsGsEAPND
0 1
LEO1 (human) PsDVDQHsGsEAPND S108-p
LEO1 (mouse) PSDEDQHSGSEAHND S108
LEO1 (rat) PSDVDQHSGSEAHND S109
S110-p
DVDQHsGsEAPNDDE
Upstream
Downstream
1 2
Effects on Modified Protein
  • intracellular localization
  • molecular association, regulation
Effects on Biological Processes:
  • apoptosis, induced
  • carcinogenesis, inhibited
  • cell growth, inhibited
  • signaling pathway regulation
  • transcription, inhibited
Phosphatases, in vitro:
  • PTP4A3 (human)
Putative upstream phosphatases:
  • PTP4A3 (human)
Treatment
  • siRNA
LEO1 (human) DVDQHsGsEAPNDDE S110-p
LEO1 (mouse) DEDQHSGSEAHNDDD S110
LEO1 (rat) DVDQHSGSEAHNDDD S111
S123
DEDEGHRSDGGSHHS
0 1
LEO1 (human) DEDEGHRSDGGSHHS S123
LEO1 (mouse) DDDEGHRsDEGsRHs S123-p
LEO1 (rat) DDDEGHRSDEGSHHS S133
S127
GHRSDGGSHHSEAEG
0 1
LEO1 (human) GHRSDGGSHHSEAEG S127
LEO1 (mouse) GHRsDEGsRHsEAEG S127-p
LEO1 (rat) GHRSDEGSHHSEAEG S137
S130
SDGGSHHSEAEGSEK
0 1
LEO1 (human) SDGGSHHSEAEGSEK S130
LEO1 (mouse) sDEGsRHsEAEGsEK S130-p
LEO1 (rat) SDEGSHHSEAEGSEK S140
S135
HHSEAEGSEKAHsDD
0 1
LEO1 (human) HHSEAEGSEKAHsDD S135
LEO1 (mouse) RHsEAEGsEKAQsDD S135-p
LEO1 (rat) HHSEAEGSEKAQsDD S145
S140-p
EGSEKAHsDDEKWGR
0 8
LEO1 (human) EGSEKAHsDDEKWGR S140-p
LEO1 (mouse) EGsEKAQsDDEKWDG S140-p
LEO1 (rat) EGSEKAQsDDEKWDG S150-p
S151-p
KWGREDKsDQsDDEK
Upstream
0 23
Treatment
  • MLN8054
LEO1 (human) KWGREDKsDQsDDEK S151-p
LEO1 (mouse) KWDGEDKsDQsDDEK S151-p
LEO1 (rat) KWDGEDKsDQsDDDE S161-p
S154-p
REDKsDQsDDEKIQN
Upstream
0 24
Treatment
  • MLN8054
LEO1 (human) REDKsDQsDDEKIQN S154-p
LEO1 (mouse) GEDKsDQsDDEKLQN S154-p
LEO1 (rat) GEDKsDQsDDDEKLQ S164-p
S162-p
DDEKIQNsDDEERAQ
Upstream
0 31
Treatment
  • MLN8054
LEO1 (human) DDEKIQNsDDEERAQ S162-p
LEO1 (mouse) DDEKLQNsDDEDREQ S162-p
LEO1 (rat) DDEKLQNsDDEEREQ S173-p
S171-p
DEERAQGsDEDKLQN
0 33
LEO1 (human) DEERAQGsDEDKLQN S171-p
LEO1 (mouse) DEDREQGsDEDKLQN S171-p
LEO1 (rat) DEEREQGsDDEKLQN S182-p
S179-p
DEDKLQNsDDDEKMQ
0 38
LEO1 (human) DEDKLQNsDDDEKMQ S179-p
LEO1 (mouse) DEDKLQNsDDDEEKM S179-p
LEO1 (rat) DDEKLQNsADEEEKM S190-p
T188-p
DDEKMQNtDDEERPQ
Upstream
0 77
Treatment
  • dasatinib
  • lapatinib
LEO1 (human) DDEKMQNtDDEERPQ T188-p
LEO1 (mouse) DEEKMQNtDDEDRAQ T189-p
LEO1 (rat) EEEKMQNtDDEDRAQ T200-p
S197-p
DEERPQLsDDERQQL
Upstream
0 75
Treatment
  • lapatinib
LEO1 (human) DEERPQLsDDERQQL S197-p
LEO1 (mouse) DEDRAQIsDDDRQQL S198-p
LEO1 (rat) DEDRAQLsDDDRQQL S209-p
S205-p
DDERQQLsEEEKANs
Upstream
0 30
Treatment
  • lapatinib
LEO1 (human) DDERQQLsEEEKANs S205-p
LEO1 (mouse) DDDRQQLsEEEKGNs S206-p
LEO1 (rat) DDDRQQLsEEEKGNs S217-p
S212-p
sEEEKANsDDERPVA
Upstream
0 26
Treatment
  • EGF
LEO1 (human) sEEEKANsDDERPVA S212-p
LEO1 (mouse) sEEEKGNsDDEHPVA S213-p
LEO1 (rat) sEEEKGNsDDERPAA S224-p
S220-p
DDERPVAsDNDDEKQ
Upstream
0 25
Treatment
  • EGF
LEO1 (human) DDERPVAsDNDDEKQ S220-p
LEO1 (mouse) DDEHPVAsDNDEEKQ S221-p
LEO1 (rat) DDERPAAsDNDEEKQ S232-p
S229-p
NDDEKQNsDDEEQPQ
0 23
LEO1 (human) NDDEKQNsDDEEQPQ S229-p
LEO1 (mouse) NDEEKQNsDDEDQPQ S230-p
LEO1 (rat) NDEEKQNsDDEDRPQ S241-p
S238-p
DEEQPQLsDEEKMQN
0 24
LEO1 (human) DEEQPQLsDEEKMQN S238-p
LEO1 (mouse) DEDQPQVsDEEKMQN S239-p
LEO1 (rat) DEDRPQVsDEEKMQN S250-p
S246-p
DEEKMQNsDDERPQA
0 15
LEO1 (human) DEEKMQNsDDERPQA S246-p
LEO1 (mouse) DEEKMQNsDDERPQV S247-p
LEO1 (rat) DEEKMQNsDDERPQV S258-p
S254-p
DDERPQAsDEEHRHs
0 14
LEO1 (human) DDERPQAsDEEHRHs S254-p
LEO1 (mouse) DDERPQVsDEDGRRs S255-p
LEO1 (rat) DDERPQVsDEDRRHs S266-p
S261-p
sDEEHRHsDDEEEQD
0 6
LEO1 (human) sDEEHRHsDDEEEQD S261-p
LEO1 (mouse) sDEDGRRsDGEEEQD S262-p
LEO1 (rat) sDEDRRHsDDEEEQD S273-p
S271-p
EEEQDHKsEsARGsD
0 3
LEO1 (human) EEEQDHKsEsARGsD S271-p
LEO1 (mouse) EEEQDQKsEsARGsD S272-p
LEO1 (rat) EEEQDQKSEsARGsD S283
S273-p
EQDHKsEsARGsDsE
0 8
LEO1 (human) EQDHKsEsARGsDsE S273-p
LEO1 (mouse) EQDQKsEsARGsDsE S274-p
LEO1 (rat) EQDQKSEsARGsDsE S285-p
S277-p
KsEsARGsDsEDEVL
Upstream
0 18
Treatment
  • ZK-Thiazolidinone
LEO1 (human) KsEsARGsDsEDEVL S277-p
LEO1 (mouse) KsEsARGsDsEDEVL S278-p
LEO1 (rat) KSEsARGsDsEDEVL S289-p
S279-p
EsARGsDsEDEVLRM
Upstream
0 34
Treatment
  • ZK-Thiazolidinone
LEO1 (human) EsARGsDsEDEVLRM S279-p
LEO1 (mouse) EsARGsDsEDEVLRL S280-p
LEO1 (rat) EsARGsDsEDEVLRM S291-p
S294-p
KRKNAIAsDsEADsD
Upstream
0 37
Treatment
  • EGF
  • SB202190
LEO1 (human) KRKNAIAsDsEADsD S294-p
LEO1 (mouse) KRKNAIPsDsEADsD S295-p
LEO1 (rat) KRKNAIPsDsEVDsD S306-p
S296-p
KNAIAsDsEADsDtE
Upstream
0 32
Treatment
  • EGF
  • SB202190
LEO1 (human) KNAIAsDsEADsDtE S296-p
LEO1 (mouse) KNAIPsDsEADsDtE S297-p
LEO1 (rat) KNAIPsDsEVDsDTE S308-p
S300-p
AsDsEADsDtEVPKD
Upstream
0 35
Regulatory protein:
  • PLK1 (human)
Treatment
  • EGF
  • SB202190
LEO1 (human) AsDsEADsDtEVPKD S300-p
LEO1 (mouse) PsDsEADsDtEVPKD S301-p
LEO1 (rat) PsDsEVDsDTEVPKD S312-p
T302-p
DsEADsDtEVPKDNS
0 9
LEO1 (human) DsEADsDtEVPKDNS T302-p
LEO1 (mouse) DsEADsDtEVPKDNN T303-p
LEO1 (rat) DsEVDsDTEVPKDNN T314
T356-p
EEEPIPEtRIEVEIP
0 2
LEO1 (human) EEEPIPEtRIEVEIP T356-p
LEO1 (mouse) EEEPIPETRIEVEIP T357
LEO1 (rat) EEEPIPETRIEVEIP T368
K364-ub
RIEVEIPkVNTDLGN
0 2
LEO1 (human) RIEVEIPkVNTDLGN K364-ub
LEO1 (mouse) RIEVEIPkVNTDLGN K365-ub
LEO1 (rat) RIEVEIPKVNTDLGN K376
Y374-p
TDLGNDLyFVkLPNF
0 3
LEO1 (human) TDLGNDLyFVkLPNF Y374-p
LEO1 (mouse) TDLGNDLYFVkLPNF Y375
LEO1 (rat) TDLGNDLYFVKLPNF Y386
K377-ub
GNDLyFVkLPNFLSV
0 33
LEO1 (human) GNDLyFVkLPNFLSV K377-ub
LEO1 (mouse) GNDLYFVkLPNFLSV K378-ub
LEO1 (rat) GNDLYFVKLPNFLSV K389
Y393
PRPFDPQYYEDEFED
0 1
LEO1 (human) PRPFDPQYYEDEFED Y393
LEO1 (mouse) PRPFDPQYYEDEFED Y394
LEO1 (rat) PRPFDPQyyEDEFED Y405-p
Y394
RPFDPQYYEDEFEDE
0 1
LEO1 (human) RPFDPQYYEDEFEDE Y394
LEO1 (mouse) RPFDPQYYEDEFEDE Y395
LEO1 (rat) RPFDPQyyEDEFEDE Y406-p
K413-ub
EEGRTRLkLkVENTI
0 4
LEO1 (human) EEGRTRLkLkVENTI K413-ub
LEO1 (mouse) EEGRTRLKLkVENTI K414
LEO1 (rat) EEGRTRLKLKVENTI K425
K415-ub
GRTRLkLkVENTIRW
0 12
LEO1 (human) GRTRLkLkVENTIRW K415-ub
LEO1 (mouse) GRTRLKLkVENTIRW K416-ub
LEO1 (rat) GRTRLKLKVENTIRW K427
K434-ub
DEEGNEIkESNARIV
0 16
LEO1 (human) DEEGNEIkESNARIV K434-ub
LEO1 (mouse) DEEGNEIkESNARIV K435-ub
LEO1 (rat) DEEGNEIKESNARIV K446
K442-ub
ESNARIVkWSDGSMS
0 1
LEO1 (human) ESNARIVkWSDGSMS K442-ub
LEO1 (mouse) ESNARIVKWSDGSMS K443
LEO1 (rat) ESNARIVKWSDGSMS K454
K461-ub
NEVFDVYkAPLQGDH
0 1
LEO1 (human) NEVFDVYkAPLQGDH K461-ub
LEO1 (mouse) NEVFDVYKAPLQGDH K462
LEO1 (rat) NEVFDVYKAPLQGDH K473
K486-ub
LQGQAVFkTkLTFRP
0 18
LEO1 (human) LQGQAVFkTkLTFRP K486-ub
LEO1 (mouse) LQGQAVFkTKLTFRP K487-ub
LEO1 (rat) LQGQAVFKTKLTFRP K498
K486-m1
LQGQAVFkTkLTFRP
0 1
LEO1 (human) LQGQAVFkTkLTFRP K486-m1
LEO1 (mouse) LQGQAVFKTKLTFRP K487
LEO1 (rat) LQGQAVFKTKLTFRP K498
K488-ub
GQAVFkTkLTFRPHS
0 5
LEO1 (human) GQAVFkTkLTFRPHS K488-ub
LEO1 (mouse) GQAVFkTKLTFRPHS K489
LEO1 (rat) GQAVFKTKLTFRPHS K500
T496-p
LTFRPHStDSATHRk
0 1
LEO1 (human) LTFRPHStDSATHRk T496-p
LEO1 (mouse) LTFRPHStDSATHRk T497-p
LEO1 (rat) LTFRPHSTDSATHRK T508
K503-ub
tDSATHRkMTLSLAD
0 3
LEO1 (human) tDSATHRkMTLSLAD K503-ub
LEO1 (mouse) tDSATHRkMTLSLAD K504-ub
LEO1 (rat) TDSATHRKMTLSLAD K515
S546-p
EEERLRAsIRREsQQ
0 1
LEO1 (human) EEERLRAsIRREsQQ S546-p
LEO1 (mouse) EEERLRASIRREsQQ S547
LEO1 (rat) EEERLRASIRRESQQ S558
S551-p
RAsIRREsQQRRMRE
0 2
LEO1 (human) RAsIRREsQQRRMRE S551-p
LEO1 (mouse) RASIRREsQQRRMRE S552-p
LEO1 (rat) RASIRRESQQRRMRE S563
S566-p
KQHQRGLsAsYLEPD
0 2
LEO1 (human) KQHQRGLsAsYLEPD S566-p
LEO1 (mouse) KQHQRGLSASYLEPD S567
LEO1 (rat) KQHQRGLSASYLEPD S578
S568-p
HQRGLsAsYLEPDrY
0 2
LEO1 (human) HQRGLsAsYLEPDrY S568-p
LEO1 (mouse) HQRGLSASYLEPDRY S569
LEO1 (rat) HQRGLSASYLEPDRY S580
R574-m1
AsYLEPDrYDEEEEG
0 1
LEO1 (human) AsYLEPDrYDEEEEG R574-m1
LEO1 (mouse) ASYLEPDRYDEEEEG R575
LEO1 (rat) ASYLEPDRYDEEEEG R586
K591-ub
SISLAAIkNRYKGGI
0 3
LEO1 (human) SISLAAIkNRYKGGI K591-ub
LEO1 (mouse) SVSLAAIKNRYKGGI K592
LEO1 (rat) SVSLAAIKNRYKGGI K603
Y606-p
REERARIyssDsDEG
0 6
LEO1 (human) REERARIyssDsDEG Y606-p
LEO1 (mouse) REERARIyssDsDEG Y607-p
LEO1 (rat) REERARIyssDsDEG Y618-p
S607-p
EERARIyssDsDEGs
0 26
LEO1 (human) EERARIyssDsDEGs S607-p
LEO1 (mouse) EERARIyssDsDEGs S608-p
LEO1 (rat) EERARIyssDsDEGs S619-p
S608-p
ERARIyssDsDEGsE
0 30
LEO1 (human) ERARIyssDsDEGsE S608-p
LEO1 (mouse) ERARIyssDsDEGsE S609-p
LEO1 (rat) ERARIyssDsDEGsE S620-p
S610-p
ARIyssDsDEGsEED
Upstream
0 39
Treatment
  • EGF
  • ischemia
LEO1 (human) ARIyssDsDEGsEED S610-p
LEO1 (mouse) ARIyssDsDEGsEED S611-p
LEO1 (rat) ARIyssDsDEGsEED S622-p
S614-p
ssDsDEGsEEDKAQR
Upstream
0 40
Treatment
  • ischemia
LEO1 (human) ssDsDEGsEEDKAQR S614-p
LEO1 (mouse) ssDsDEGsEEDKAQR S615-p
LEO1 (rat) ssDsDEGsEEDKAQR S626-p
T629-p
LLKAKKLtsDEEGEP
0 20
LEO1 (human) LLKAKKLtsDEEGEP T629-p
LEO1 (mouse) LLKAKKLNsDEEGES N630
LEO1 (rat) LLKAKKLNsDEEGES N641
S630-p
LKAKKLtsDEEGEPs
Upstream
0 61
Treatment
  • EGF
  • quinalizarin
LEO1 (human) LKAKKLtsDEEGEPs S630-p
LEO1 (mouse) LKAKKLNsDEEGESS S631-p
LEO1 (rat) LKAKKLNsDEEGESS S642-p
S637-p
sDEEGEPsGKRKAED
0 1
LEO1 (human) sDEEGEPsGKRKAED S637-p
LEO1 (mouse) sDEEGESSGKRKAED S638
LEO1 (rat) sDEEGESSGkRKAED S649
K639
EEGEPsGKRKAEDDD
0 1
LEO1 (human) EEGEPsGKRKAEDDD K639
LEO1 (mouse) EEGESSGKRKAEDDD K640
LEO1 (rat) EEGESSGkRKAEDDD K651-ac
Y655
ANKKHKKYVIsDEEE
0 2
LEO1 (human) ANKKHKKYVIsDEEE Y655
LEO1 (mouse) ANKKHKKyVIsDEEE Y656-p
LEO1 (rat) ANKKHKKYVIsDEEE Y667
S658-p
KHKKYVIsDEEEEDD
Upstream
0 90
Treatment
  • nocodazole
LEO1 (human) KHKKYVIsDEEEEDD S658-p
LEO1 (mouse) KHKKyVIsDEEEEED S659-p
LEO1 (rat) KHKKYVIsDEEEEED S670-p